• Journal of Fisheries and Marine Sciences Education
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• v.20 no.1
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• pp.107-120
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• 2008

Building a competency of pre-service school teachers is one of the critical factors to decide right direction of k-12 computer & information education. In this context, we can realize of the importance of computer & information curriculum for pre-service school teachers. The purpose of this study is to explore the case of the CEL(Computer Educator License) program in Indiana University and to find the developmental direction of technology education for pre-service school teachers. To achieve the purpose of study, the methods and procedures involved the following steps: The literature reviews of technology education were performed. The analysis framework based on case study method was designed for collecting data. Data were composed of related documents, web resources, and interview resources. And collected data were analyzed. The finding and recommendation of this study were the importance of following factors: (a) technology integration in the curriculum for pre-service school teachers, (b) differentiated management with skill-based technology education, (c) leadership for using and diffusing technology in the school, and (d) connected curriculum with the national standard indicator.

• Biomedical Science Letters
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• v.24 no.4
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• pp.426-429
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• 2018

Chronic eosinophilic leukemia (CEL) is characterized by eosinophilia and organ damage. Imatinib is widely used for treating CEL, chronic myeloid leukemia (CML) and acute myeloid leukemia (AML). Unfortunately, the cancer cells gain resistance against the drug after prolonged molecular-targeted therapies. Imatinib-resistant EoL-1 (EoL-1-IR) cells were produced from chronic eosinophilic leukemia cells (EoL-1) after treatment with imatinib for a long duration. Two-dimensional electrophoresis (2-DE) analysis revealed numerous protein variations in the EoL-1 and EoL-1-IR sub-types. Compared to the EoL-1 cells, expression levels of TIP49, RBBP7, ${\alpha}$-enolase, adenosine deaminase, C protein, galactokinase, eukaryotic translation initiation factor, $IFN-{\gamma}$, and human protein homologous to DROER were increased, whereas core I protein, proteasome subunit p42, heterogeneous ribonuclear particle protein, chain B, and nucleoside diphosphate were decreased in the EoL-1-IR cells. Taken together, these results contribute to understanding the pathogenic mechanism of drug-resistant diseases.

• Asian-Australasian Journal of Animal Sciences
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• v.6 no.2
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• pp.291-300
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• 1993

The agronomic, morphologic and nutritive measurements were determined for ten varieties of the early-, medium- and late- maturing rice from five types of soil in south of China. The results are shown that (1) The higher contents of neutral detergent fibre (NDF), cellulose (CEL), hemicellulose (HC) and lignin (LIG), but lower crude protein (CP) and neutral detergent solubles (NDS) contents were noted for the whole plant of rice straw during maturation; (2) As far as the feed nutritive value, segments (S) is highest, then leaf blades (LB), leaf sheaths (LS) lowest. However, LB and LS are constituted about 75% of whole plant, the nutritive value of rice straw is depended upon the nutritive quality of LB and LS; (3) The dry matter disappearances (DMD) values of different spots of rice straw are different, the eary-maturing highest, then the medium; the late- lowest; (4) The DMD value of different fractions is different, S highest, then LB, LS lowest; (5) The different retention time in rumen, the DMD value of rice straw is different. As time following, the DMD value increased gradually, during 48-72 h, the DMD value achieves close to highest; (6) The grain yield (r = -0.91), plant height (r = -0.87) and full-filling grain percent (r = -0.75) are correlated negatively with DMD value, but the leaf/stem (r = 0.59) and the proportion of stem (r = 0.58) are correlated positively with DMD value. The relations between chemical compositions and DMD value are: Early-: DMD = 7.372 + 0.055 DM - 0.532 CP - 2.487 NDF + 1.143 ADF + 0.214 CEL + 1.456 HC + 0.718 LIG (r = 0.61). Medium-: DMD = 333.927 + 2.026 DM - 0.224 CP - 4.602 NDF + 4.524 ADF + 0.149 CEL + 2.923 HC + 0.035 LIG (r = 0.79). Late-: DMD = 133.284 + 0.282 DM - 3.455 CP - 22.185 NDF + 24.267 ADF + 0.316 CEL - 23.288 HC + 0.945 LIG (r = 0.79). Therefore, it is possible to predict the nutritive value of rice straw on the basis of the agronomic, morphologic measurements and chemical compositions and the relationship with DMD value.

• Horticultural Science & Technology
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• v.19 no.4
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• pp.505-510
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• 2001

To improve germinability of carrot seeds of 'Inari', 'Mansan', 'Mussang', and 'Hongsim' cultivars, various levels of solid matrix priming (SMP) and the physiological changes of seeds associated with SMP were examined. As the ratio of water in a seed-Micro Cel E-water mix and priming duration increased, seed germinability enhanced. However, there was radicle protrusion during SMP in some cultivars, indicating the existence of cultivar different variations of the optimum conditions. The optimum ratio for a seed-Micro Cel E-water mix was 5 : 3 : 10.5. In this mix, the optimum durations for the treatment were 3 days for 'Mansan' and 5 days for other cultivars. SMP at $20^{\circ}C$ to $25^{\circ}C$ resulted in a higher germination percentage and a shorter $T_{50}$. Seeds absorbed water quickly within an hour and the percentage of moisture was stable at 43 to 49 after 24 hours of the treatment. Conductivity of the mix declined for the first 6 hours to $100{\mu}S{\cdot}cm^{-1}$ with little changes thereafter. On the other hand, the pH of the mixed increased slightly during the early phase, and then returned to the initial level as the treatment proceeded.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.30 no.2
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• pp.13-23
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• 1998

Two major cellulase components purified with sephadex G-75 and DEAE sepharose were applied to bleached kraft pulp to inverstigate the change of fiber properties. Cellulose viscosity was very sensitive to $C_x$ component treatment (more than 15% drop was observed) while being little influenced by $C_1$, component (only 2% drop). Fiber fraction longer than 2mm was reduced by $C_x$ treatment while short fiber fraction was increased greatly by more than 15%. There was little change in fiber length distribution by combined treatment of $C_1$ 1 and $C_x$ at equal. In this case, fine contents increased by more than 2.5% at equivalent refining time. WRV and Density were increased as the amount of $C_1$ or $C_x$ treatment was increased. $C_{x}$ was main cause for increasing them. But the effect fell as enzyme dosage.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.34C no.2
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• pp.50-60
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• 1997

Reconfiguration of a memory array using spare rows and columns has been known to be a useful technique to improve the yield. When the numbers of spare rows and scolumns are limited, respectively, the repair problem is known to be NP-complete. In this paper, we propose the reconfiguration algorithm for an array of memory cells using faulty cel clustering, which removes rows and columns algrithm is the simplest reconfiguration method with the time complexity of $O(n^2)$, where n is the number of faulty cells, however the repair rate is very low. Whereas the exhaustive search algorithm has a high repair rate, but the time complexity is $O(2^n)$. The proposed algorithm provides the same repair rate as the exhaustive search algorithm for almost all cases and runs as fast as the greedy method. It has the time complexity of $O(n^3)$ in the worst case. We show that the propsed algorithm provides more efficient solutions than other algorithms using simulations.

• Preventive Nutrition and Food Science
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• v.3 no.2
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• pp.163-168
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• 1998

Inhibitory effect of indole oligomers induced from indole-3-carbinol(I3C) on the growth of breast cancer cells was studied. We gernerated the reaction mixtures (RXM) at ambient temperature by treating a stirred aqueous solution of I3C (typeically 0.25ml) at a concentration of 12 $\mu$mol/ml) with hydrochloric acid (typically 28$\mu$l of a 1 mmol/ml solution). RXM was fractionated by the column chromatography. The fractions with similar UV-pattern were further fractionated by HPLC and 3.3'-diindoylmethane (DIM) and other indole oligomers were identified. I3C, RXM, and it derived indole compounds were added to MCF-7 cells and cultured in the presence of 10-7M estradiol for 7 days. the growth-inhibitory effect of I3C and DIM on the growth of MCF-7 cell was very strong. The synthetic DIM also revealed antiproliferative effect on MCF-7 cel. The fractions containing high DIM content (77%), were most effective in inhibiting MCF-7 cell growth induced by estradiol. With these results, we suggest that I3C and DIM might have anticarcinogenic effect on the breast cancer.

• Geomechanics and Engineering
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• v.23 no.3
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• pp.245-259
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• 2020

Tunnels have become an indispensable part of metro cities. Blast resistance design of tunnel has attracted the attention of researchers due to numerous implosion event. Present paper deals with the non-linear finite element analysis of rock tunnel having shear zone subjected to internal blast loading. Abaqus Explicit schemes in finite element has been used for the simulation of internal blast event. Structural discontinuity i.e., shear zone has been assumed passing the tunnel cross-section in the vertical direction and consist of Highly Weathered Granite medium surrounding the tunnel. Mohr-Coulomb constitutive material model has been considered for modelling the Highly Weathered Granite and the shear zone material. Concrete Damage Plasticity (CDP), Johnson-Cook (J-C), Jones-Wilkins-Lee (JWL) equation of state models are used for concrete, steel reinforcement and Trinitrotoluene (TNT) simulation respectively. The Coupled-Eulerian-Lagrangian (CEL) method of modelling for TNT explosive and air inside the tunnel has been adopted in this study. The CEL method incorporates the large deformations for which the traditional finite element analysis cannot be used. Shear zone orientations of 0°, 15°, 30°, 45°, 60°, 75° and 90°, with respect to the tunnel axis are considered to see their effect. It has been concluded that 60° orientation of shear zone presents the most critical situation.

• BMB Reports
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• v.28 no.5
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• pp.387-391
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• 1995

In order to investigate whether phospholipase C (PLC) activity in oat celIs is regulated by Gprotein, we have characterized PLC in plasma membranes of oat tissues. To identify the purified plasma membrane, $K^+$-stimulated, $Mg^{2+}$-dependent ATPase activity was measured. The activity of ATPase was shown to be proportional to the concentration of membrane protein. To examine the PLC activity regulated by G-protein, we used the inside-out and outside-out plasma membrane mixture isolated from the oat cells. The plasma membrane mixture showed higher PLC activity than the one of the outside-out plasma membrane. This suggests that PLC activity is located at the cytoplasmic surface of plasma membrane. PLC activity in plasma membrane mixture was dependent on $Ca^{2+}$ with maximum activity at 100 ${\mu}m$ $Ca^{2+}$ and it was inhibited by 1 mM EGTA. Using Sep-pak $Accell^{TM}$ Plus QMA chromatography, we found that inositol 1,4,5-trisphosphate ($IP_3$) was produced in the presence of 10 ${\mu}m$ $Ca^{2+}$. The PLC activity in the membrane was enhanced by an activator of G-protein ($GTP{\gamma}S$) and not by an inhibitor ($GDP{\beta}S$). This indicates that a G-protein is involved in the activation of PLC in the plasma membrane of oat cells.

• Asian-Australasian Journal of Animal Sciences
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• v.9 no.1
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• pp.51-56
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• 1996

In this Experiment three wether male Matou goats (♂), all fitted with permanent rumen fistulae, were used to study the rumen degradabilities (incubation time 48h) of dry matter (DM), neutral detergent fibre (NDF), acid detergent fibre (ADF), acid detergent ligin (ADL), cellulose (CEL) and hemicellulose (HC) and their contents of wheat and rice straws were determined for the different morphological fractions and segments. The results showed that the variation of different fractions for wheat and rice straw is the true resources of their nutritive value variation and the cell wall contents of wheat and rice straw are also obviously different. The rumen degradabilities of different straw fibre are significantly different (p<0.01), mean while the effect of straw variety is also significant (p<0.05). The aim was to set up a foundation for studying the rumen degradation of the roughage resources.