• Journal of the Optical Society of Korea
• /
• 제9권4호
• /
• pp.131-134
• /
• 2005

We have proposed a method to calculate the absorption coefficients for the bound-to-continuum transitions in a strong biased quantum-well infrared photodetector. We have applied this method to a manufactured sample of typical device parameters, and obtained good agreements with experiments. The absorption coefficients evaluated are up to 5,700/cm at some particular operating conditions. We have also been able to make a qualitative explanation for the bias dependence of response.

• Toxicological Research
• /
• 제35권4호
• /
• pp.331-341
• /
• 2019

Cancer is one of the common causes of death with a high degree of mortality, worldwide. In many types of cancers, if not all, sex-biased disparities have been observed. In these cancers, an individual's sex has been shown to be one of the crucial factors underlying the incidence and mortality of cancer. Accumulating evidence suggests that differentially expressed genes and proteins may contribute to sex-biased differences in male and female cancers. Therefore, identification of these molecular differences is important for early diagnosis of cancer, prediction of cancer prognosis, and determination of response to specific therapies. In the present review, we summarize the differentially expressed genes and proteins in several cancers including bladder, colorectal, liver, lung, and nonsmall cell lung cancers as well as renal clear cell carcinoma, and head and neck squamous cell carcinoma. The sex-biased molecular differences were identified via proteomics, genomics, and big data analysis. The identified molecules represent potential candidates as sex-specific cancer biomarkers. Our study provides molecular insights into the impact of sex on cancers, suggesting strategies for sex-biased therapy against certain types of cancers.

• 정신신체의학
• /
• 제30권2호
• /
• pp.55-65
• /
• 2022

공감적 존재인 Homo Empathicus로서의 인간들이 살아가는 세상임에도 불구하고, 실제로 우리 사회는 집단간의 분열과 갈등이 끊이지 않고 있다. 인간의 공감 반응은 타자의 정의로움에 민감하여, 타인의 정의로움 여부에 따라 타인의 고통에 공감 반응을 보이기도 하고 쾌감을 느끼기도 한다. 그러나, 타자에 대한 우리의 공감 반응은 항상 정의로운 것은 아니며, 내집단 편향성이라는 내재적 한계를 가지고 있다. 즉, 자신과 같은 집단이나 범주에 속하는 사람인지 아닌지에 따라, 우리는 스스로 의식하지도 못한 채 타인의 고통에 편향적으로 공감하기도 하고, 편향적으로 쾌감을 느끼기도 한다. 최근의 정보통신기술 발전은, 내집단 관련 SNS혹은 내집단 매체에 대한 편향적 접근을 용이하게 하며, 이를 통해 집단과 관련한 보다 편향된 의미론적 정보 네트워크의 구축을 심화시킨다. 이러한 현상들은 공감의 내재적 한계 속성들과 상호작용하여 더욱 편향된 내집단 공감 및 내집단 활동을 하게 하는 악순환의 고리를 형성함으로써 분열과 대립을 가속화할 수 있다. 저자는 공감의 신경 기전에 대한 이해를 통해 공감의 속성과 한계를 고찰해보고, 신경과학적 관점에서 공감과 정의의 관련성을 탐색해봄으로써, 분열과 갈등의 현대 사회를 기존의 사회과학적 시각과는 다른 차원에서 조명해보고자 하였다.

• Parasites, Hosts and Diseases
• /
• 제51권6호
• /
• pp.637-644
• /
• 2013

This study aimed to investigate the antibody responses in mice immunized with Gnathostoma spinigerum crude antigen (GsAg) incorporated with the combined adjuvant, a synthetic oligonucleotide containing unmethylated CpG motif (CpG ODN 1826) and a stable water in oil emulsion (Montanide ISA720). Mice immunized with GsAg and combined adjuvant produced all antibody classes and subclasses to GsAg except IgA. IgG2a/2b/3 but not IgG1 subclasses were enhanced by immunization with CpG ODN 1826 when compared with the control groups immunized with non-CpG ODN and Montanide ISA or only with Montanide ISA, suggesting a biased induction of a Th1-type response by CpG ODN. After challenge infection with live G. spinigerum larvae, the levels of IgG2a/2b/3 antibody subclasses decreased immediately and continuously, while the IgG1 subclass remained at high levels. This also corresponded to a continuous decrease of the IgG2a/IgG1 ratio after infection. Only IgM and IgG1 antibodies, but not IgG2a/2b/3, were significantly produced in adjuvant control groups after infection. These findings suggest that G. spinigerum infection potently induces a Th2-type biased response.

• 한국건설관리학회논문집
• /
• 제16권2호
• /
• pp.38-45
• /
• 2015

건설위험관리 프로세스의 위험분석단계는 정성적 및 정량적 위험분석단계로 세분화되는데, 정성적 위험분석이 주된 역할을 하고 정량적 위험분석은 보조적인 역할을 담당한다. 그런데 이제까지 정성적 위험분석단계에서 위험도를 계량화하는 방법으로 적용되어온 위험도 산정 공식은 발생확률과 영향을 단순히 곱하는 식으로서 결과 값들은 저위험도에 편중된 분포를 나타낸다. 이에 대한 대안으로 고위험도에 편중되는 산정 공식이 제안되었으나, 위험도 분포가 저위험도 또는 고위험도에 편중하게 될 경우 대부분의 자연현상이 정상분포에 가깝다는 통계학적인 일반논리에 부합되지 않는다. 본 연구에서는 위험도의 분포가 중앙에 집중되는 새로운 위험도 산정방법을 제안하고자 한다. 이를 통해 위험도 분포가 자연현상의 정상분포와 유사한 형식으로 표현됨으로써 위험에 대응하는 수준이 고위험도 또는 저위험도에 치우지지 않고 중간위험도에서 합리적으로 선택될 수 있게 하고자 한다. 나아가 위험도 산정방법에 대한 추가적인 선택사항을 제공함으로써 위험분석 방법의 융통성과 합리성을 향상시키는데도 일조하고자 한다.

• 대한전기학회논문지:전기물성ㆍ응용부문C
• /
• 제48권10호
• /
• pp.687-692
• /
• 1999

A new technique to measure low level capacitance variations of the gyroscope is proposed and verified by computer simulation. It is based on the new CV(capacitance-voltage) converter circuit biased by dc current source and the peak detector without low pass filter. The CV converter biased by dc current source provides good signal-to-noise ratio and this setup of the detection circuitry without low pass filter makes it possible to provide short settling time, that is, higher speed of measurement and wide operation range if only a few parameters are adjusted. The key parameters that affect the performance of the detection circuitry are illustrated and computer simulation results are presented. The demonstrated detection circuitry shows linear response from 10 fF to 130 fF at 10 kHz and shows good linearity.

• 센서학회지
• /
• 제23권1호
• /
• pp.1-6
• /
• 2014

In many medical image devices, dc noise often prevents normal diagnosis. In wireless capsule endoscopy systems, multipath fading through indoor wireless links induces inter-symbol interference (ISI) and indoor electric devices generate impulsive noise in the received signal. Moreover, dc noise, ISI, and impulsive noise are also found in optical fiber communication that can be used in remote medical diagnosis. In this paper, a blind signal processing method based on the biased probability density functions of constant modulus error that is robust to those problems that can cause error propagation in decision feedback (DF) methods is presented. Based on this property of robustness to error propagation, a DF version of the method is proposed. In the simulation for the impulse response of optical fiber channels having slowly varying dc noise and impulsive noise, the proposed DF method yields a performance enhancement of approximately 10 dB in mean squared error over its linear counterpart.

• 대한기계학회논문집A
• /
• 제28권11호
• /
• pp.1733-1740
• /
• 2004

In the transverse flux linear induction motor(TFLIM) with the general secondary composed of conductor and back-yoke, there exists a magnetized force into the normal direction or the air-gap direction of the thrust motion as well as the thrust force. Therefore, the various methodologies have been tried to use the normal force by the two independent control variables of the multi-phase input. But, as the force depends inevitably and strongly on the thrust force, it is essential to decouple both forces for two control index. In this paper, we suggest a novel approach capable of compensating the couple between both forces and the control index by using the DC-biased multi-phase input, and then realizing the independent control of TFLIM.

• 전자공학회논문지B
• /
• 제33B권6호
• /
• pp.45-53
• /
• 1996

In this paper, the convergence behavior of timing phase when an adaptive partial response equalizer and decision-directed type of a PLL work together in a digital recording channel is described. The phenomena of getting biased in timing phase when the convergence parameter of an adaptive partial response equalizer and timing recovery constant of a PLL are not selected properly is introduced. The phenomena, occurring due to perturbation of timing phase, are analyzed, by computer simulation and the region of ocnvergence for timing phase is discussed. Also, a method to overcome the phenomena using a variable step-size parameter is described.

• 한국항공운항학회지
• /
• 제26권4호
• /
• pp.64-75
• /
• 2018

A status of air traffic controller is a government officer and air traffic controllers who work at airport are divided by duty rating and work experience. Abiding by law, rules and regulation, air traffic controllers are working together based on mutual trust. This paper's theoretical background is based on cultural bias theory. The theory divide people group into four groups according to cultural bias such as fatalism, hierarchy, individualism and egalitarianism. A research model was designed how such four cultural bias could affect air traffic controller's risk response in case of emergency or abnormal situation during their work. Depend on empirical research, it was found that air traffic controllers perceived they had been more biased to fatalism than hierarchy. The characteristics of fatalism group are as follows: first of all, they follow rigid rules and regulation. However, they have less self-efficacy compared to other government officers. According to structural equation model, air traffic controller's fatalism had a significant negative effect on organizational royalty. Their royalty, however, had a very significant positive effect on planning response and immediate response.