• Journal of Korean Academy of Nursing
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• v.46 no.3
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• pp.420-430
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• 2016

Purpose: The purpose of this study was to test a hypothetical model of chemotherapy-related cognitive impairment (CRCI) and depression in people with gastrointestinal cancer. Methods: A purposive sample of 198 patients undergoing chemotherapy was recruited from November 2014 to July 2015. The instruments were Everyday Cognition (ECog), Hospital Anxiety Depression Scale (HADS), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), and M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module. Data were analyzed using descriptive statistics, correlation, and path analysis. Results: CRCI was directly affected by cancer symptoms (${\beta}=.19$, p=.004) and fatigue (${\beta}=.56$, p<.001)($R^2=47.2%$). Depression was directly affected by fatigue (${\beta}=.48$, p<.001) and CRCI (${\beta}=.27$, p<.001). However, The impact of cancer symptoms on depression was confirmed through the mediating effect of CRCI. Conclusion: Results indicate that in patients with gastrointestinal cancer undergoing chemotherapy along with the direct physiologic effects (fatigue, symptoms) of cancer treatment may have altered cognitive function leading to depression.

• Journal of Korean Critical Care Nursing
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• v.10 no.1
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• pp.31-40
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• 2017

Purpose: The purpose of this study was to identify the factors influencing on burnout in operating room nurses. Methods: Using a cross-sectional design, a total of 109 operating room nurses working at 7 general hospitals with 300 beds or more in B city were analyzed. The instruments used for this study assessed job stress, resilience, professional identity, and burnout. Data was analyzed using descriptive statistics, a t-test, an ANOVA, a Pearson's correlation coefficient and a multiple regression analysis. Results: There was a statistically significant correlation between burnout and job stress (r=.53, p<.001), resilience (r=-.59, p<.001), and professional identity (r=-.47, p<.001). The factors influencing burnout include job stress (${\beta}=.27$, p<.001), resilience(${\beta}=-.37$, p<.001), dissatisfaction with the nursing job (${\beta}=.32$, p<.001), and moderate satisfaction with the nursing job (${\beta}=.19$, p=.014), and the explanatory power was 53.0%. Conclusions: The results suggest that intervention to reduce job stress and to improve resilience, which were the factors influencing burnout in operating room nurses, is necessary.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.5
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• pp.1339-1347
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• 2016

The purpose of this study was to identify factors of influencing cervical cancer and Human papilloma virus(HPV) infection preventive behavioral intention of nursing students. The research design for this study was a descriptive survey design. Data collection was done using self-report questionnaires with 218 nursing students in B city from November 30 to 15 December, 2015. Data were analyzed using percentage, mean, standard deviation, t-test, ANOVA, Pearson's correlation analysis and multiple regression with SPSS Win 21.0 program. The significant factors of cervical cancer and HPV infection preventive behavioral intention was cervical cancer knowledge(${\beta}=.246$, p<.001), health belief about HPV vaccination(${\beta}=-.223$, p<.001), HPV vaccination(${\beta}=.173$, p=.008), and Gynecological Disease History(${\beta}=.145$, p=.026). And these factors explained 15.4% of the variance in the cervical cancer and HPV Infection preventive behavioral intention. In conclusion, the results of this study indicated that it's a need to develop the effective education program in addition to knowledge improvement on HPV and cervical cancer for nursing students.

• YAKHAK HOEJI
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• v.35 no.5
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• pp.372-378
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• 1991

To increase the stability and bioavailability of Omeprazole(OMP), which is used newly as a proton-pump inhibitor, inclusion complex of OMP with $\beta$-cyclodextrin($\beta$-CD) was prepared by coprecipitation method and its characteristics were ascertained by means of solubility test, DSC, IR, and the accelerated stability analysis. The type of OMP inclusion complex is classified as Bs-type on phase solubility diagram, and the stoichiometric ratio of OMP: $\beta$-CD complex is 1:2 and formation constant is 80.82/mole. The solubility of the complex could be increased remarkably by complexation compare with OMP. Degradation process of both OMP and OMP complex followed apparent first-order kinetics, of which degradation rate constants and activation energies are k$_{25}$=8.1$\times$10$^{-4}$/day, E$_{a}$=22 Kcal/mole (OMP), and k$_{25}$=4.65$\times$10$^{-6}$/day, E$_{a}$=35 Kcal/mole (complex), respectively. These results show the increase of the stability and solubility of OMP markedly, therefore it is believed that the improvement of stabilization for OMP by inclusion complexation might be practically available.

• Journal of East-West Nursing Research
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• v.19 no.2
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• pp.121-127
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• 2013

Purpose: The purpose of this study was to determine the effects of knowledge and attitude on self efficacy of cardiopulmonary resuscitation (CPR) in the fifth and the sixth grade of elementary school students. Methods: The participants were 242 elementary school students from A city. Data were collected from August 26 to August 27, 2013 using a questionnaire. Data analysis was performed by SPSS/WIN 19.0 using ANOVA, t-test, Pearson correlation and stepwise multiple regression. Results: Factors affecting on self efficacy to CPR were attitude (${\beta}=.54$), religion (${\beta}=-.16$), recognition (${\beta}=.15$) and knowledge (${\beta}=.13$). These factors explain 47.0% of the variance in self efficacy. Conclusion: The results of this study show that attitude to CPR has the strongest influence on efficacy. Based on the results of this study, we suggest that customized programs and further research by using 2010 guideline are needed to develop for elementary school students.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.5
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• pp.419-425
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• 2007

We have found out the relationship of nanoemulsion containing nano vitamin C, E and propolis and gingival disease. We've confirmed effect of nanoemulsion through the experiment of in vivo and in vitro. We tested cell viability of gingival fibroblast cells by MTT assay and mRNA appearance of interleukin-$1{\beta}$, using mouse that was guided inflammation. Anti-microbacterial activity for Antibacterial effect's experiment was carried out by using S.aureus and E.coli. In addition, inflammation tissue has been observed with scanning electrical microscopy. In this study, expression of interleukin-$1{\beta}$ was decreased after adding nanoemulsion containing nanovitamin C, E and propolis. We've also obtained good results from the test of Antibacterial effect against S.aureus and E.coli. Also, swelling of inflammation tissues observed by scanning electrical microscopy has gone down. In conclusion, we have gained confidence that nanoemulsion containing nano vitamin C, E and propolis has very high Antibacterial effect against bacteria in oral. And it made us guess that inflammation of gingival reduces after decreasing interleukin-$1{\beta}$. Thus, we expect that nanoemulsion containing nano vitamin C, E and propolis gives good effects to patient having gingival disease.

• Korean Journal of Health Education and Promotion
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• v.25 no.4
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• pp.67-82
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• 2008

Purpose: The objective of this study were to examine the determinants of self-rated health, specially focused on the effect of functional capacity of community dwelling sedentary older adults on self-rated health. Method: The data has been collected from 654 community-dwelling sedentary older adults (mean age: 75 years) during the period from April to June in 2007. The data were collected by the in-person interview and direct measurement of functional capacity. The data were analyzed using chi-square test and multiple regression analysis with the SPSS 9.1 program. Result: The elderly rated their health as very good (3%), good (28%), fair (38%), poor (29%0, and very poor (2%). The higher average daily walk minutes ($\beta$=0.12, p<.01), number of chair stand ($\beta$=0.10, p<.05), scores of self-efficacy ($\beta$=0.16, p<.001) and the lower number of disease ($\beta$=-0.44, p<.001) show better self-rated health. Conclusion: Self-rated health is the most commonly used indicators in social epidemiology and geriatric research because it has been known as the good predictor of mortality and reflects health related disability. The finding suggested that daily walking habits, lower body strength, physical self-efficacy should be considered to improve the senior's self-perception of health. The community-based intervention associate increase these factors should be considered.

• Journal of Korean Academy of Psychiatric and Mental Health Nursing
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• v.27 no.4
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• pp.332-341
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• 2018

Purpose: The purpose of this study was to determine the impacts of vocational calling, emotional intelligence, and major commitment on nursing college students' happiness. This study also was conducted to explore major commitment's mediating effect on the relationship between vocational calling, emotional intelligence, and major commitment among nursing college students. Methods: Participants were 346 nursing college students. Data were collected in November, 2017 with self-report questionnaires and were analyzed using t-test, one-way ANOVA, Pearson's correlation coefficients, and regression analysis with IBM SPSS 19.0. Results: The regression model explained 33.0% of variance in nursing college students' happiness (F=41.44, p<.001). Significant factors were emotional intelligence (${\beta}=.30$, p<.001), grade (${\beta}=.20$, p<.001), major commitment (${\beta}=.18$, p=.002), and vocational calling (${\beta}=.11$, p=.035). Moreover, major commitment showed partial mediating effects on vocational calling and happiness. Major commitment also showed partial mediating effects on emotional intelligence and happiness. Conclusion: The results suggest that nursing college students' happiness can be increased through strategies aimed at increasing vocational calling, emotional intelligence, and major commitment.

• Women's Health Nursing
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• v.25 no.1
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• pp.73-85
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• 2019

Purpose: To determine whether maternal attitude toward sex during pregnancy and health-related quality of life could influence sexual function of pregnant women. Methods: In this study, 138 second and third trimester pregnant women completed self-report questionnaires during their visits to women's hospitals or community health centers to assess their general characteristics, attitude toward sex during pregnancy (PIES-M), health-related quality of life (EQ-5D), and sexual function (FSFI-6K). Multiple regression analysis was performed to test the research model with SPSS version 23. Results: Pregnant women who had discontinued their sexual life after recognizing their pregnancy accounted for 27.5% of women questioned. The average sexual function score of pregnant women was higher in the second trimester than the third trimester. Attitude toward sex during pregnancy (${\beta}=-.38$, p<.001), maintaining sexual life (${\beta}=.20$, p=.028), health-related quality of life (${\beta}=.18$, p=.030), and adverse symptoms during sex (${\beta}=.18$, p=.042) were determinants of sexual function during pregnancy. Conclusion: Nurses in antenatal care units need to help pregnant women maintain a positive attitude toward sexual activity during pregnancy and manage their health-related quality of life to maintain their sexual life during pregnancy.

• Journal of Korean Public Health Nursing
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• v.32 no.3
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• pp.468-481
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• 2018

Purpose: The purpose of this study was to identify the factors influencing the reproductive health behavior of married immigrant women (MIW). Methods: A cross-sectional based survey was conducted. The data were collected using a self-reporting questionnaire of MIW who lived in cities and provinces. The data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation, and multiple regression analysis. Results: A total of 141 subjects participated in the study (mean age, $34.23{\pm}6.53$). Of the participants, 45.4% were Vietnamese. The reproductive health behavior score of the subjects was $4.09{\pm}0.51$. The reproductive health behavior showed positive correlations with attitude (r=.37, p<.001), perceived behavioral control (r=.35, p<.001) and intent (r=.33, p<.001). The factors influencing the reproductive health behavior were attitude toward the reproductive health behavior (${\beta}=.24$, p=.005), perceived behavioral control (${\beta}=.18$ p=.046), experience of breast feeding (${\beta}=.20$, p=.014), and the self-evaluated Korean listening ability (${\beta}=.18$, p=.019). These variables explained 29% of the variance in the reproductive health behavior. Conclusion: According to the above results, a specific educational program for MIW is needed to increase their reproductive health behavior.