• Herbal Formula Science
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• v.14 no.1
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• pp.11-29
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• 2006

This report describes 71 studies related to the use of Radix Saposhnikoviae main blended prescription from Donguibogam. The following conclusion were reached through investigations on the prescriptions that use Radix Saposhnikoviae as a main ingredient. Prescriptions that Radix Saposhnikoviae was taken as a monarch drug are utilized for 20 therapeutic purposes, for example, eye disease, wind disease, head disease and Sang Han syndromes. In particular, 28.1% of prescriptions appear in the chapter of eye, and 25.3% of those appear in the chapter of head. Prescriptions that utilize Radix Saposhnikoviae as the main ingredient are used in the treatment of eye disease. paralysis and tetanus. Radix Saposhnikoviae is used in pathogenic factors such as wind. wind with cold. and used in pathology related to liver system. The dosage of Radix Saposhnikoviae in prescriptions is 7 li(about 0.26 gram) to 2.5 jeon(about 9.38 gram), however 1 jeon(about 3.75 gram) has been taken the most for clinical application. Bangpungtang is the most useful base prescription which use the Radix Saposhnikoviae as the main ingredient.

• Herbal Formula Science
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• v.18 no.2
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• pp.93-108
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• 2010

This report was studied 72 cases studies related to the use of Pericarpium Citri Reticulatae Virdie mainly blended prescriptions from Dongeuibogam. The following conclusion were reached through investigations on the prescriptions that use Pericarpium Citri Reticulatae Virdie as a key ingredient. Prescriptions that Pericarpium Citri Reticulatae Virdie was taken as a monarch drug are utilized for 25 therapeutic purposes, for example, abdominal mass, children disease, malaria and abdominal dropsy. In particular, 13.9% of prescriptions appear in the chapter of abdominal mass, and 12.5% of those appear in the chapter of children. Prescriptions that utilize Pericarpium Citri Reticulatae Virdie as the main ingredient are used in the treatment of abdominal mass, abdominal dropsy, scrotal hernia and malaria. Pericarpium Citri Reticulatae Virdie is used in pathogenic factors such as cold and used in pathology related to the spleen system. The dosage of Pericarpium Citri Reticulatae Virdie is 1bun(about 0.375 gram) to 4jeon(about 15 gram), however 5bun(about 1.875 gram) to 8bun(about 3 gram) has been taken the most for clinical application. Yukmisamleunghwan and Hyungbongjeonwon are the most useful base prescriptions which use the Pericarpium Citri Reticulatae Virdie as the main ingredient.

• The Journal of Korean Medical History
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• v.34 no.2
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• pp.89-96
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• 2021

This research aims to find a way to utilize the literature to select the herbs to be added or subtracted according to the condition of the patient after determining the basic prescription to be used for the patient. The study is based on data concerning the herbal composition and application of prescriptions described in the Donguibogam. The composition herbs was expressed as a weight ratio, the standard deviation of the weight ratio was calculated for each prescription, and the case where the weight ratio was greater than the base value (highest weight ratio - standard deviation) was designated as a principal herb. The various expressions of applications were changed to representative terms by the researcher and used to calculate the frequency. Of the 4,373 prescriptions for Donguibogam, 3,307 were able to be expressed in terms of weight ratios with 640 prescriptions using Rehmannia glutinosa, Cnidium officinale, Angelica gigas and Paeonia lactiflora as the principle herb. Of the 640 prescriptions, 508 prescriptions included applied information. Rehmannia glutinosa can also be used for symptoms such as fetal leakage(胎漏), short ingestion(食少), fever(發熱), dazed expression(眼花). Cnidium officinale can also be used for symptoms such as migraine(偏頭痛), stroke(中風癱瘓), tetanus(破傷風). Angelica gigas can also be used for symptoms such as forgetfulness(健忘), incontinence of urination(小便不通), palpitations(驚悸). Paeonia lactiflora can also be used for symptoms such as heart pain and abdominal pain(心腹痛), cough(咳嗽).

• Herbal Formula Science
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• v.27 no.2
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• pp.167-178
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• 2019

Objectives : This report describes 45 studies related to the use of Rhizoma dioscoreae main blended prescription from Donguibogam. Methods : The following conclusion were reached through investigations on the prescriptions that use Rhizoma dioscoreae as a key ingredient. Prescriptions that Rhizoma dioscoreae was taken as a monarch drug are utilized for 18 therapeutic purposes, for example, internal injury, stool disease, pediatric disease. In paticular, 24% of prescriptions appear in the chapter of internal injury, and 18% of those appear in the chapter of stool. Results : Prescriptions that utilize Rhizoma dioscoreae as the main ingredient are used in the treatment of indigestion, diarrhea and paralysis. Rhizoma dioscoreae is used in pathogenic factors such as water, water with damp, and used in pathology related to stomach system. Conclusions : The dosage of Rhizoma dioscoreae is 8li(about 0.29 gram) to 3jeon(about 11.25 gram), however 1jeon(about 3.75 gram) has been taken the most for clinical application. Sagunjatang and Siljangsan is the most useful base prescription which use the Rhizoma dioscoreae as the main ingredient.

• International journal of advanced smart convergence
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• v.12 no.4
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• pp.434-442
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• 2023

The relationship between acute kidney injury (AKI) prediction and nephrotoxic drugs, or drugs that adversely affect kidney function, is one that has yet to be explored in the critical care setting. One contributing factor to this gap in research is the limited investigation of drug modalities in the intensive care unit (ICU) context, due to the challenges of processing prescription data into the corresponding drug representations and a lack in the comprehensive understanding of these drug representations. This study addresses this gap by proposing a novel approach that leverages patient prescription data as a modality to improve existing models for AKI prediction. We base our research on Electronic Health Record (EHR) data, extracting the relevant patient prescription information and converting it into the selected drug representation for our research, the extended-connectivity fingerprint (ECFP). Furthermore, we adopt a unique multimodal approach, developing machine learning models and 1D Convolutional Neural Networks (CNN) applied to clinical drug representations, establishing a procedure which has not been used by any previous studies predicting AKI. The findings showcase a notable improvement in AKI prediction through the integration of drug embeddings and other patient cohort features. By using drug features represented as ECFP molecular fingerprints along with common cohort features such as demographics and lab test values, we achieved a considerable improvement in model performance for the AKI prediction task over the baseline model which does not include the drug representations as features, indicating that our distinct approach enhances existing baseline techniques and highlights the relevance of drug data in predicting AKI in the ICU setting.

• Herbal Formula Science
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• v.19 no.2
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• pp.161-178
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• 2011

Objectives : The aim of this study is to find the therapeutic meaning of Rhizoma Cyperi in herbal medication. Methodes : In this study, we investigate 85 prescriptions related to the use of Rhizoma Cyperi main blended from Dongeuibogam. we research about field of therapy, symtoms of a disease, the chief virtue of a medicine, the cause of a disease, the pathology of a disease, dosage, contents of composition. Results : The following conclusions were reached through investigations on the prescriptions that use Rhizoma Cyperi as the main ingredient. Prescriptions that Rhizoma Cyperi was taken as a monarch drug are utilized for 24 therapeutic purpose, for example, woman disease, uterine disease, vitality and abdominal mass. In particular, 16.4% of prescriptions appear in the chapter of woman, and 15.2% of those appear in the chapter of uterus. Prescriptions that utilize Rhizoma Cyperi as the main ingredient are used in the treatment of menstrual disorder, pain due to disorder of Gi, infertility, irregular menstruation and abdominal mass. Rhizoma Cyperi is used in pathogenic factors such as seven modes of emotions and used in pathology related to the stagnation of blood system. The dosage of Rhizoma Cyperi is 6li(about 0.23g) to 6don(about 22.5g), however 1don(about 3.75g) has been taken the most for clinical application. Gyogamdan and Yukmisamleunghwan are the most useful base prescriptions which use the Rhizoma Cyperi as the main component. Conclusions : This information provide the rationale for establishing Basic evidance in the oriental medical prescription.

• Herbal Formula Science
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• v.22 no.1
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• pp.13-32
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• 2014

Objectives : Until now the study of Cnidii Rhizoma, hemorrhage, brain waves, such as ischemic brain injury, analgesic, effect overcome of the stress from pregnancy melanin formation and inhibiting effects skin whitening have been published regarding this article. Cnidii Rhizoma demonstrates its different abilities depending on the characteristics. This paper reported that effect of Cnidii Rhizoma in Dongeuibogam blended prescriptions as main medicine. In addition, by analyzing data, we studied about utilizing of Cnidii Rhizoma. Methods : Cnidii Rhizoma in Dongeuibogam Prescriptions as the main ingredient was built with database of 202 prescriptions. Thus analyzed data was summarized in detail.(Table-1) If there is no difference in the title of the prescription but in other case the configuration information is different, formulations 1 and 2 were divided by the table. Results : The following results were reached through investigations on the prescriptions usikng Cnidii Rhizoma as a key component. 1. Prescriptions taking Cnidii Rhizoma as a monarch drug are utilized for 40 therapeutic purposes. In particular, 12.3% of prescriptions appear in the chapter of head, and 10.8% of those appear in the chapter of women, and 9.4% of eye, 8.9% of child, 6.4% of wind disease respectively. 2. Prescriptions utilizing Cnidii Rhizoma as the main ingredient are used in the treatment of headache, dizziness and pregnancy hemorrhage fetal movement, premature birth and they are also used for treating 131 different types of disease. 3. The dosage of Cnidii Rhizoma in formulas is from 2pun(about 0.75g) to 5don(nearly 18.75g), however 1don(nearly 3.75g) has been taken the most for clinical application. 4. We find out that according to herbs or prescriptions, Cnidii Rhizoma has a variety of functions such as ascending & descending of energy. Samultang is the most useful base prescription which used the Cnidii Rhizoma as the main component. Conclusion : These results suggest that, Cnidii Rhizoma once-amount use (don nearly 3.75g) 4g in head, gynecology, ophthalmology, pediatrics and paralysis disease associated with oriental medicine resource development can be considered to be widely used These results suggest that Cnidii Rhizoma was used most with 1 don(4g) and can be widely used for the resource development to the disease such as brain, gynecology, ophthalmologhy, pediatrics and wind-associated symptoms.

• The Journal of Dong Guk Oriental Medicine
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• v.3
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• pp.151-162
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• 1994

Studying documents & papers on the cure of male sterility led to conclusion as follows. 1. The methodes of cure were applied Onbosinyang, Jaeumbosin, Soganheul, Joseubhwadam, Boickgihyul, Hwalhyeolhwaua, Boickbisin, etc. And the causes of disease were applied Sinyanghue, Sineumhue, Ganulgiche, Damseubneon, Gihwelyanghue, Gichehyeolul, Bisinyanghue, etc. 2. Prescription were applied Chanyukdan Ojayuenjonghwan on Sinyanghue, Yukmi.iihwanghwan Jibekjihwanghwan on Sinuemhue, Sihosogansan Soyosan on Ganulgiche, Changchuldodamtang Bihebunchungeum on Damseubneon, Sibjyundaebotang Paljintang on Gihyeolyanghue, Sobokchukuatang Gueasengjungtang on Gichehyeolul, Sibjayukguntang Bisinssangbohwan on Bisinyanghue, etc, and Ojayunjonghwan being added on the base to cure another causes of disease as well as Sinhue. 3. The causes of disease were presented to be Sin hue mostly ; Sinyanghue particularly. And there were usually 25~42years old, married lives of 3~8years, cure periods of 2~5months, general effectiveness(approximately 76%), pregnancies(approximately 47%). 4. The methodes of cure in oriental medical prepared with the causes of disease in western one are showed in below ; The cause of semen formation disorder is considered the methodes of cure in Onbosinyang, Jaeumbosin, Boickbisin and the cause of functional ejaculation disorder in mind is considered the method of cure in Sogangegwu on the base in Bosin.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2003.10a
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• pp.219-223
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• 2003

현대사회는 정치, 경제, 행정, 문화 등 인류가 더불어 살아가면서 형성된 모든 영역이 정보통신 시스템을 통해 생성되고 유포되는 지식정보 기반의 사회구조로 급속히 진행되고 있고 정보화 시대가 현실화되면서 인터넷의 사용빈도도 급속히 증가하여 개인의 사생활이나 개인정보는 중요한 이슈가 되고 있는 실정이다. 네트워크와 인터넷의 발달로 많은 분야가 오프라인에서 온라인과 전자처리 방식으로 바뀌어 가고 있다. 이러한 정보통신의 변화와 개인정보의 중요성은 의료 환경에도 많은 변화를 가져오고 있다. 현재 의약분업이후 병원과 약국간의 종이 처방전 시스템에 대한 문제점이 발생되고 있다. 또한 전자처방전 시스템이 개발되어 있으나 아직 필수적인 인증 및 보안을 비롯한 각종 정보위협에 대한 대책 수립이 완전하지 않은 실정이다. 따라서 이러한 정보보호 서비스 유지 및 신뢰성을 보장해 줄 수 있는 PKI를 이용한 전자처방전 시스템을 연구하고자 한다.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06b
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• pp.73-75
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• 2006

운동 처방을 목적으로 보급되고 있는 많은 시스템들이 단순한 처방식과 외국의 통계데이터를 기반으로 구현되어 있어, 많은 경우 운동 처방사의 주관이나 경험에 의존하여 개인에게 맞는 정확한 운동 처방을 제공하지 못하고 있다. 본 연구에서는 전문화된 운동 능력 평가 및 처방 지식에 대한 데이터베이스를 구축하고, 이를 기반으로 개개인의 특성에 맞는 체계적인 운동 처방을 도출할 수 있는 운동 처방 전문가 시스템을 개발하였다. 개발된 시스템은 현재 시범 운영중이며, 운동 처방에 관한 전문인력이 부족한 중소규모의 체육 시설에서도 객관적이고 전문적인 운동 처방 서비스 제공이 가능할 것으로 기대한다.