• Title/Summary/Keyword: Yuan-hong

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Salt Processed Food and Gastric Cancer in a Chinese Population

  • Lin, Si-Hao;Li, Yuan-Hang;Leung, Kayee;Huang, Cheng-Yu;Wang, Xiao-Rong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.13
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    • pp.5293-5298
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    • 2014
  • To investigate the association between salt processed food and gastric cancer, a hospital based case-control study was conducted in a high risk area of China. One hundred and seven newly diagnosed cases with histological confirmation of gastric cancer and 209 controls were recruited. Information on dietary intake was collected with a validated food frequency questionnaire. Unconditional logistic regression was applied to estimate the odds ratios with adjustment for other potential confounders. Comparing the high intake group with never consumption of salt processed foods, salted meat, pickled vegetables and preserved vegetables were significantly associated with increased risk of gastric cancer. Meanwhile, salt taste preference in diet showed a dose-response relationship with gastric cancer. Our results suggest that consumption of salted meat, pickled and preserved vegetables, are positively associated with gastric cancer. Reduction of salt and salt processed food in diets might be one practical measure to preventing gastric cancer.

Online railway wheel defect detection under varying running-speed conditions by multi-kernel relevance vector machine

  • Wei, Yuan-Hao;Wang, You-Wu;Ni, Yi-Qing
    • Smart Structures and Systems
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    • v.30 no.3
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    • pp.303-315
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    • 2022
  • The degradation of wheel tread may result in serious hazards in the railway operation system. Therefore, timely wheel defect diagnosis of in-service trains to avoid tragic events is of particular importance. The focus of this study is to develop a novel wheel defect detection approach based on the relevance vector machine (RVM) which enables online detection of potentially defective wheels with trackside monitoring data acquired under different running-speed conditions. With the dynamic strain responses collected by a trackside monitoring system, the cumulative Fourier amplitudes (CFA) characterizing the effect of individual wheels are extracted to formulate multiple probabilistic regression models (MPRMs) in terms of multi-kernel RVM, which accommodate both variables of vibration frequency and running speed. Compared with the general single-kernel RVM-based model, the proposed multi-kernel MPRM approach bears better local and global representation ability and generalization performance, which are prerequisite for reliable wheel defect detection by means of data acquired under different running-speed conditions. After formulating the MPRMs, we adopt a Bayesian null hypothesis indicator for wheel defect identification and quantification, and the proposed method is demonstrated by utilizing real-world monitoring data acquired by an FBG-based trackside monitoring system deployed on a high-speed trial railway. The results testify the validity of the proposed method for wheel defect detection under different running-speed conditions.

A Study on the System of Official Uniforms Established by Emperor Hong-wu(洪武) of the Ming(明) Dynasty (명 홍무제의 관복제정에 관한 연구)

  • Chun Hea-Sook;Ryoo Jae-Woon
    • Journal of the Korean Society of Costume
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    • v.55 no.2 s.92
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    • pp.70-81
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    • 2005
  • This paper researches the system of official uniforms and characteristics of the system based on Ming-Shi(明史), Da-Ming-Hui-Dian(大明會典) and Hong-Wu-Li-Zhi(洪武禮制) in the emperor Hong-wu(洪武帝) of Ming dynasty(明). The system could be divided in to three terms, i.e., the early (initial), the middle and the end (last) terms. In the first(1368) & the third year of the emperor's reign (1370) the system of official uniforms was simple f9r his people not to be luxurious and for revived the system of official uniforms of the Han dynasty(漢) and annulled the system of the Yuan dynasty(元), be-cause the country was not stable yet. During the middle term of Hong-wu, the 14th (1381) to 16th (1383) year of his reign, people attained luxurious lives and developed a strong sense of rank as the country became more stable. As a result, the system became more complicated when the emperor used the costumes to represent political and social ranking. In the end of the emperor's age, the 23rd (1390) to 26th (1393), it reveals his strong intention to establish a system of costumes that separated the ruler from the ruled. He wanted to strengthen the power of Emperor for his little grandson, Jian-wen(建文帝), who would succeed to the throne and would have absolute power. These changes became fundamental to the Ming dynasty's costume system and the Ming dynasty kept them for long time.

A novel computer vision-based vibration measurement and coarse-to-fine damage assessment method for truss bridges

  • Wen-Qiang Liu;En-Ze Rui;Lei Yuan;Si-Yi Chen;You-Liang Zheng;Yi-Qing Ni
    • Smart Structures and Systems
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    • v.31 no.4
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    • pp.393-407
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    • 2023
  • To assess structural condition in a non-destructive manner, computer vision-based structural health monitoring (SHM) has become a focus. Compared to traditional contact-type sensors, the advantages of computer vision-based measurement systems include lower installation costs and broader measurement areas. In this study, we propose a novel computer vision-based vibration measurement and coarse-to-fine damage assessment method for truss bridges. First, a deep learning model FairMOT is introduced to track the regions of interest (ROIs) that include joints to enhance the automation performance compared with traditional target tracking algorithms. To calculate the displacement of the tracked ROIs accurately, a normalized cross-correlation method is adopted to fine-tune the offset, while the Harris corner matching is utilized to correct the vibration displacement errors caused by the non-parallel between the truss plane and the image plane. Then, based on the advantages of the stochastic damage locating vector (SDLV) and Bayesian inference-based stochastic model updating (BI-SMU), they are combined to achieve the coarse-to-fine localization of the truss bridge's damaged elements. Finally, the severity quantification of the damaged components is performed by the BI-SMU. The experiment results show that the proposed method can accurately recognize the vibration displacement and evaluate the structural damage.

In vitro Arsanilic Acid Induction of Apoptosis in Rat Hepatocytes

  • Yuan, Hui;Gong, Zhi;Yuan, li-Yun;Han, Bo;Han, Hong-Ryul
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.9
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    • pp.1328-1334
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    • 2006
  • This paper aimed to study the toxicity of arsanilic acid on rat primary hepatocytes in vitro by a modification of the perfusion method. The conditions included concentrations of 0, 1.085, 10.85, 108.5, 1,085 and 10,850 mg/kg arsanilic acid in RPMI 1,640 medium at rat hepatocytes plates respectively, each group had five repeats at $37^{\circ}C$ for 48 h. The rat primary hepatocytes survival ratio, DNA Ladder, activities of glutathione peroxidase (GSH-px), superoxide dismutase (SOD) and catalase (CAT) in hepatocytes, activity of SOD in the medium and the expression of gene bax in hepatocytes were measured at 12 h, 24 h and 48 h respectively. The results showed that arsanilic acid decreased the activities of GSH-px and SOD, and increased the activity of CAT in all dosages, and affected as positive DNA ladder. Although the SOD activities of both hepatocytes and medium in 1.085 mg/L arsanilic acid were significantly lower than the base line at 12 h, CAT activity in 10.85 mg/L arsanilic acid was significantly higher than the base line at 48 h, and all of the DNA ladders were positive, which means 1.085 mg/L arsanilic acid induced apoptosis at 24 h. The gene expression of bax was significantly upregulated in 1.085 mg/L arsanilic acid or higher for 24 h.The parameters in 1,085 mg/L and 10,850 mg/L arsanilic acid had more severe changes than the others at any time indicating that these levels of arsanilic acid were toxic hazards for hepatocyte survival. It was concluded that arsanilic acid induced a dosage- and time-dependent gene expression of bax, 1.085 mg/L arsanilic acid could be involved in rat liver cell apoptosis at 24 h. Arsanilic acid as additives in livestock feed could present potential toxic implications for farm animals.

No association Between Calcium Channel Blockers and Survival in Patients with Cancer: A systematic Review and Meta-analysis

  • Sun, Hong;Zhuang, Rong-Yuan;Li, Tao;Zheng, Yuan-Ting;Cai, Wei-Min
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.3917-3921
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    • 2016
  • Background: The association between calcium channel blockers (CCBs) and survival in cancer patients remains unclear and the results of related studies are conflicting. The objective of the study was to investigate the association between calcium channel blockers (CCBs) use and survival in cancer patients. Materials and Methods: We searched PubMed, EMBASE, Web of Science and Cochrane Library for studies published before January 2016 with the terms related to CCBs and survival in cancer patients. The information was reviewed and extracted by two evaluators independently. Data of publications was extracted and calculated into hazard ratios (HRs) for overall survival (OS). Statistical analysis was performed by using Review Manager 5.3. Results: There were 11 studies included in our meta-analysis. Analysis of all studies showed that CCBs use was not associated with survival in cancer patients (HR=1.07; 95% CI: 0.91-1.25; P=0.42). No association between CCBs use and overall survival in cancer patients was existed whether in Asian (HR=1.18, 95% CI: 0.72-1.93; P=0.52) or Caucasian population (HR=1.03, 95% CI: 0.89-1.20; P=0.66). Conclusions: There is no evidence that CCBs use is associated with a better or worse outcome of survival in cancer patients.

Mitogen-Activated Protein Kinase Signal Transduction in Solid Tumors

  • Lei, Yuan-Yuan;Wang, Wei-Jia;Mei, Jin-Hong;Wang, Chun-Liang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8539-8548
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    • 2014
  • Mitogen-activated protein kinase (MAPK) is an important signaling pathway in living beings in response to extracellular stimuli. There are 5 main subgroups manipulating by a set of sequential actions: ERK(ERK1/ERK2), c-Jun N(JNK/SAPK), p38 MAPK($p38{\alpha}$, $p38{\beta}$, $p38{\gamma}$ and $p38{\delta}$), and ERK3/ERK4/ERK5. When stimulated, factors of upstream or downstream change, and by interacting with each other, these groups have long been recognized to be related to multiple biologic processes such as cell proliferation, differentiation, death, migration, invasion and inflammation. However, once abnormally activated, cancer may occur. Several components of the MAPK network have already been proposed as targets in cancer therapy, such as p38, JNK, ERK, MEK, RAF, RAS, and DUSP1. Among them, alteration of the RAS-RAF-MEK-ERK-MAPK(RAS-MAPK) pathway has frequently been reported in human cancer as a result of abnormal activation of receptor tyrosine kinases or gain-of-function mutations in genes. The reported roles of MAPK signaling in apoptotic cell death are controversial, so that further in-depth investigations are needed to address these controversies. Based on an extensive analysis of published data, the goal of this review is to provide an overview on recent studies about the mechanism of MAP kinases, and how it generates certain tumors, as well as related treatments.

Liu Yi and Hong Jung Ha's Kai Fang Shu (유익(劉益)과 홍정하(洪正夏)의 개방술(開方術))

  • Hong, Sung-Sa;Hong, Young-Hee;Kim, Young-Wook
    • Journal for History of Mathematics
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    • v.24 no.1
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    • pp.1-13
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    • 2011
  • In Tian mu bi lei cheng chu jie fa(田畝比類乘除捷法) of Yang Hui suan fa(楊輝算法)), Yang Hui annotated detailed comments on the method to find roots of quadratic equations given by Liu Yi in his Yi gu gen yuan(議古根源) which gave a great influence on Chosun Mathematics. In this paper, we show that 'Zeng cheng kai fang fa'(增乘開方法) evolved from a process of binomial expansions of $(y+{\alpha})^n$ which is independent from the synthetic divisions. We also show that extending the results given by Liu Yi-Yang Hui and those in Suan xue qi meng(算學啓蒙), Chosun mathematican Hong Jung Ha(洪正夏) elucidated perfectly the 'Zeng cheng kai fang fa' as the present synthetic divisions in his Gu il jib(九一集).

Mathematical Structures and SuanXue QiMeng (수학적(數學的) 구조(構造)와 산학계몽(算學啓蒙))

  • Hong, Sung Sa;Hong, Young Hee;Lee, Seung On
    • Journal for History of Mathematics
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    • v.26 no.2_3
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    • pp.123-130
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    • 2013
  • It is well known that SuanXue QiMeng has given the greatest contribution to the development of Chosun mathematics and that the topics and their presentation including TianYuanShu in the book have been one of the most important backbones in the developement. The purpose of this paper is to reveal that Zhu ShiJie emphasized decidedly mathematical structures in his SuanXue QiMeng, which in turn had a great influence to Chosun mathematicians' structural approaches to mathematics. Investigating structural approaches in Chinese mathematics books before SuanXue QiMeng, we conclude that Zhu's attitude to mathematical structures is much more developed than his precedent ones and that his mathematical structures are very close to the present ones.

Siyuan Yujian in the Joseon Mathematics (조선(朝鮮) 산학(算學)의 사원옥감(四元玉鑑))

  • Hong, Sung Sa;Hong, Young Hee;Lee, Seung On
    • Journal for History of Mathematics
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    • v.30 no.4
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    • pp.203-219
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    • 2017
  • As is well known, the most important development in the history of Chinese mathematics is materialized in Song-Yuan era through tianyuanshu up to siyuanshu for constructing equations and zengcheng kaifangfa for solving them. There are only two authors in the period, Li Ye and Zhu Shijie who left works dealing with them. They were almost forgotten until the late 18th century in China but Zhu's Suanxue Qimeng(1299) had been a main reference for the Joseon mathematics. Commentary by Luo Shilin on Zhu's Siyuan Yujian(1303) was brought into Joseon in the mid-19th century which induced a great attention to Joseon mathematicians with a thorough understanding of Zhu's tianyuanshu. We discuss the history that Joseon mathematicians succeeded to obtain the mathematical structures of Siyuan Yujian based on the Zhu's tianyuanshu.