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The Study on the Whitening Effect of Ephedra sinica Extract (마황추출물의 미백효과에 관한 연구)

  • Yoo Yung-Geun;Joung Min-Seok;Choi Song-Wan;Kim Joong-Hoi
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.2 s.51
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    • pp.153-159
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    • 2005
  • In this study, we investigated the application of an extract from Ephedra sinica which has been composed of traditional Korean medicine as a whitening ingredient. The extract of Ephedra sinica which was obtained from the mixture of methanol and water (1:1) the inhibitory effect of tyrosinase. Then, Ephedra sinica was extracted by two different solvents. One was water and the other was methylene chloride. Only, the water extract of Ephedra sinica showed the inhibitory effort of tyrosinase; the anti-tyrosinase activity with $0.2\%$ of the water extract was $60.6\%$. But the extract of Ephedra sinica in methylene chloride fraction showed little inhibitory effect on tyrosinase. The inhibitory effect of the concentrated water extract of Ephedra sinica was tested on L-DOPA auto-oxidation and melanin synthesis in B-16 melanoma. In L-DOPA auto-oxidation, $0.5\%$ of the concentrated water extract showed $87\%$ of inhibition of L-DOPA auto-oxidation and the $0.75\%$ concentrated Ephedra sinica extract in wafer fraction inhibited $98.8\%$ of that. In melanin synthesis of B-16 melanoma, the concentrated water effect of Ephedra sinica inhibited $70.2\%$ or $79.9\%$ of inhibitory effect on that at the concentration of $0.05\%$ or $0.075\%$, respectively. For verifying the skin whitening effect of the concentrated water extract of Ephedra sinica in vivo, we performed the clinical test of that. The research showed the significant skin whitening effect of a cream containing $0.5\%$ Ephedra sinica extract and the statistical analysis showed a significant difference (p < 0.05) between sample (containing $0.5\%$ Ephedra sinica extract) and placebo after 10 weeks.

The Validation of Standardized Nursing Care Plans Developed for Computerized Use in Clinical Practice (간호업무 전산화를 위해 개발된 표준화된 간호계획서의 타당성 검정)

  • 김용순
    • Journal of Korean Academy of Nursing
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    • v.21 no.3
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    • pp.349-364
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    • 1991
  • Recognition of the usefulness and the importance of the nursing diagnosis is increasing. There is a prevailing opinion that nursing diagnosis should be used to improve the quality of nursing care. Developing standardized nursing care palns based on nursing diagnoses is therefore considered one of the most essential projects for professional growth and improvement in the nursing world of Korea. Consequently, in the first stage of this research project, the ten nursing diagnses used most frequently with patients on medical and surgical wards were determined and related nursing care plans were developed, implemented and evaluated. The application of the standardized nursing care plans raised the nurses' confidence and proved to be effective in enhancing the quality of nursing care. This study was initiated as the next stage, to develop, test, and determine the validity of nursing care plans for the remaining nursing diagnoses. Nineteen medical and surgical wards were selected for the study ; the 176 staff nurses working on those wards and 1211 patients hospitalized there (603 patients during the nursing care plan use) took part in the project. The following summarizes the results of the study : 1. After listing all the nursing diagnoses up to the 20th in frequency from each ward except the ten used in the first study, 22 nursing diagnoses were selected. Two related to ‘self care deficit’, were combined into one. Standardized nursing care plans were established for these 21 nursing diagnoses. 2. The first page of each nursing care plan lists the related factors and defining characteristics as supporting data. The application rate distribution revealed that the majority were recorded less than 50% of the time. For each nursing diagnosis, only one to three related factors were recorded more than 50% of the time regardless of the number of suggested related factors, and similarly, only one to five defining characteristics were recorded more than 50% of the time regardless of the number of suggested defining characteristics. Therefore, these factors and defining characteristics were proposed as the common related factors and the typical signs and symptoms for each nursing diagnosis. 3. The application rate distribution for the expected outcomes, and the nursing orders that were the main data of each nursing care plan occurred more than 50% of the time, unlike the related factors and the characteristics that occurred less frequently. These findings supported the clinical validity. 4. In an effort to evaluate indirectly the effect of the use of the standardized nursing care plans, nurses' job satisfaction and perceptions of their ability in the use of the nursing process were measured and compared. Scores after the use of the plans were significantly higher than those before. The experience in actually using the standardized nursing care plans with patients increased the nurses' professional and emotional satisfaction and their confidence in using the nursing process. Also when the nurses who actually used the nursing care plans were asked to rate their effectiveness, the highest score was given to ‘the ease of establishing the nursing goal’, followed by ‘improved professional advice and care for patients’, ‘the efficiency and systemization of charting’, ‘the definite recognition of the nursing problem’, and ‘the selection of effective and appropriate nursing interventions’ in descending order. The results indicate the nurses were very positive about the effect of the real clinical application of standardized nursing care plans, and that the objective of this study to utilize the nursing diagnosis to strengthen the nursing process was attained.

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Studies on the Indirect Measuring Method of the Maximum Voluntary Ventilation (최대환기능의 간접측정법에 관한 연구)

  • Park, Hae-Kun;Kim, Kwang-Jin;Sung, Hae-Sook;Jeon, Byung-Sook
    • The Korean Journal of Physiology
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    • v.11 no.2
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    • pp.45-50
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    • 1977
  • The maximum voluntary ventilation (MVV) is one of the most widely used pulmonary function test, but its measuring method was very difficult and unreliable. However, it is need to get more easy and simple measuring method of MVV. Therefore, this study was attempted to get more easy and simple measuring method of MVV by means of the forced expiratory volume $(FEV_{T})$. The young and healthy 1,000 Korean students(592 male and 408 female) were cheesed for this purpose and whose ages were from 8 to 20 years. A spirometer (9L, Collins Co.) was used for the MVV and FEV, and they were measured 3 times at standing position, and the highest value was used. In the measurements, the subjects for MVV were asked for the breath as fast and deeply as possible for 12 seconds, and for FEV were asked for the rapid and forceful exhalation after a maximal inhalation (forced expiratory curve). In the FEV measurements toward the end of the expiration, the subjects were exhaused to continue the effort until no further gas was expired. During these measurements, the investigator stood by the subject to give a constant encouragement. FEV were calculated in the volume exhaled during the one-half $(FEV_{0{\cdot}5,}\;ml)$, the first second $(FEV_{1{\cdot}0,}\;ml)$ and the percentage of the total vital capacity exhaled during the one-half second $(FEV_{0{\cdot}5,}\;%)$. The results are summarized as follows: 1) The values of MVV were increased linearly with ages until 20 in both sexes. The values of male at the age of 20 was $168.2{\pm}2.5L/min$, and female at the age of 17 was $112.3{\pm}3.0L/min$, respectively. 2) The values of FEV (ml) were increased linearly with ages until 20 in both sexes. The values of $FEV_{0{\cdot}5}$ were $2,797{\pm}65.7ml$ in the male of 20 years and were $2,088{\pm}54.6ml$ in the female of 17 years, and of $FEV_{1{\cdot}0$ were $4,119{\pm}68.2ml$ in the male of 20 years and were $2,897{\pm}65.9ml$ in the female of 17 years, respectively. 3) The correlation coefficients between MVV and $FEV_{0{\cdot}5}\;or\;FEV_{1{\cdot}0$ (ml) were 0.82 or 0.85 in the male, and 0.77 or 0.79 in the female, respectively. 4) The prediction formulae for MVV to be derived from above results were: For male: MVV (L/min) =7.19+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=11.25+$0.04{\times}FEV_{1\cdot0}(ml)$ For female: MVV (L/min)=16.03+$0.05{\times}FEV_{0\cdot5}(ml)$, MVV (L/min)=9.47+$0.03{\times}FEV_{1\cdot0}(ml)$.

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Social Support and Quality of Life for the Elderly in Rural Areas (일 농촌지역 노인의 사회적 지지와 삶의 질)

  • Kang, Kyung-Sook
    • Research in Community and Public Health Nursing
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    • v.14 no.3
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    • pp.375-384
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    • 2003
  • The purpose of this study is to identify the amount of social support and quality of life perceived by elderly people in rural areas and to examine the relationship between social support and quality of life in an effort to provide the basic data for effective nursing intervention to enhance quality of life among elderly people. Data were collected from a sample of 220 elderly people aged over 60 from a stratified probability method from one rural area in South Jeolla province from Aug. 15 to Sep. 15, 2002. For data collection, pre-educated researchers visited the participants' homes and surveyed them face-to-face. The statistical analysis was performed using the SAS program along with t-test, ANOVA, and Pearson Correlation. The findings were as follows: 1. The most socially supportive people they answered were Spouses (57.28%), followed by children, friends/neighbors, in descending order. In terms of satisfaction about social support, the subjects felt the most satisfaction from spouses, followed by friends/neighbors, children, in descending order. 2. The participants' perceived social support was 26.0 and the highest score was 108.0 out of 125. Also, the average score and average grade point was 81.7 and 3.35, respectively. A comparison of the average grade points per items within sub-areas of social support revealed financial aid(3.56), informative support(3.34), emotional support (3.27), and evaluation support(3.22). 3. Their perceived social support had statistically significant differences in terms of how much they earned (F=18.56, p= .00001) and whether they had family members living together (F=2.68, p= .0512), quality of life had statistically significant differences in terms of how much they earned (F=35.34, p= 0.00001). 4. The quality of life they perceived was the lowest score 47.0, the highest score 196.0, average score 145.7, and average grade points 3.28. A comparison of the average grade points per items within sub-areas of quality of life revealed neighbor relationships(3.97), self-esteem(3.49), family relationships(3.35), economic conditions 3.12), physical health (2.98), and psychological health(2.74). 5. The relationship between the amount of the subjects' social support and quality of life was significantly correlated (r=.696, p< .001). The findings revealed that social support for elderly people in rural areas was a greatly effective factor on their quality, of life. Also, it was shown that the larger the social support for the elderly, the greater the quality of life for them. Therefore, it is necessary to foster geriatric nurse specialists and develop nursing intervention programs connected with health care and social wellbeing in order to enhance the quality of life of elderly people in rural areas. Also, it is necessary to develop effective models for community and its applications, which will playa leading role for elderly people.

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The Relationship of Job Satisfaction and Quality of Life on the Dental Technicians (치과기공사의 직무만족도와 삶의 질의 관련성)

  • Kwon, Eun-Ja;Han, Min-Soo
    • Journal of Technologic Dentistry
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    • v.34 no.3
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    • pp.249-261
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    • 2012
  • Purpose: This study was carried out in order to examine the relationship of job satisfaction and quality of life on the dental technicians and to analyze its influence. Methods: A self-reported questionnaire survey was carried out by having convenience sampling as 220 dental technicians who work in Seoul Metropolis, Gyeonggi-do Province, Daejeon and Chungnam Province from March 12, 2012 to April 13. A research tool was used questionnaire that was proved reliability and validity. It was prepared with totally 50 questions such as 12 items for subjects' general characteristics, 18 items for job satisfaction measurement, and 20 items for life quality measurement. An analysis of the collected data was computationally processed by using SPSS Win 17.0 program. An analytical technique was made by using statistical techniques such as frequency & percentage, T-test or One-way ANOVA analysis. The following are the analytical results of the collected materials. Results: As a result of analyzing research subjects' job satisfaction level, there was significant difference(P<0.05) in items of religion, hobby life, working environment, and rest time out of daily work. The whole mean in job satisfaction was indicated to be relatively high with 3.13. However, job satisfaction with social recognition, salary, and safety was indicated lowly. As a result of analyzing research subjects' life quality level, there was significant difference(P<0.05) in items of religion, hobby life, working environment, and rest time out of daily work. The whole mean in quality of life was indicated to be relatively high with 3.10. However, the satisfaction was indicated lowly in the whole life quality and the life environment sphere. As a result of analyzing correlation between job satisfaction and life quality, all variables were indicated to be positive correlation in high significance level, thereby having been indicated that the higher job satisfaction leads to the higher life quality. Conclusion: As a result of research, the dental technicians' job satisfaction was indicated to have high correlation with quality of life. An effort is judged to be necessary for establishing fair compensation system, improving welfare policy and enhancing social recognition and position in order to promote dental technicians' quality of life.

An Operating Scheme for the Course-based Qualification System at the Four-Year University Level: Focused on the KOREATECH Case (4년제 대학 과정평가형 자격과정 운영방안: 코리아텍 사례를 중심으로)

  • Oh, Chang-Heon;Kang, Seung-Chan;Min, Dong-Kyun;Om, Kiyong
    • Journal of Practical Engineering Education
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    • v.8 no.1
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    • pp.39-47
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    • 2016
  • Owing to increasing concern that jobseekers are wasting too much time and effort building up so-called "spec" skills to get a decent job, many companies including state-run enterprises are now hiring rookies based on their job competency rather than test scores unrelated to the job. However, universities which are mainly responsible for training professional personnel needed for various kinds of companies and factories are reluctant to adopt NCS-based educational courses. The NCS defines how much knowledge and skill are required to work in a certain industry and then evaluates them. Although the Korean government and several junior colleges have been tentatively operating the course-based qualification system at the "industrial technician" level since 2014, the results are falling far short of diverse stakeholders' expectations. Therefore, there are urgent needs to study how to develop NCS-based curriculum at the university level, and how to strengthen the linkage between work, training, and qualification.

Development of PBL Package - focusing on dental hygienist roles - (치과위생사 역할중심의 문제중심학습 패키지 개발)

  • Jung, Young-Ran;Hwang, Yoon-Sook
    • Journal of Korean society of Dental Hygiene
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    • v.4 no.1
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    • pp.119-132
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    • 2004
  • The purpose of this study was to introduce PBL to dental hygienist education in an effort to raise a question about the inauthentic and inappropriate curriculum. PBL is one of learning methods to enhance the problem-solving ability of learners, and it's attempted to develop a PBL package focusing on dental hygienist roles to lay the foundation for producing competent and expert dental hygienists with a good problem- solving ability. The literature concerned was reviewed from November 2002 through January 2003 to determine whether or not PBL was applicable to dental-hygienist course, and that turned out to be effective for dental hygienist education. And then a PBL package was developed to train students to be knowledgeable and have a knowhow and excellent problem-solving skills. The characteristics of the PBL package could be described as follows: First, that focused on dental hygienist roles to serve the purpose of this study to remedy the current unrealistic and improper curriculum and improve the problem-solving skills of learners. Second, time factor was taken into account. In this four-week course for two credits, there are four classes a week, and it's required to take six or eight weeks to apply the PBL package, which is expected to demotivate students. Therefore, it's planned to conduct more weekly classes to make a proper progress. Third, a wide variety of teaching aids were put to use, and learner would be encouraged to be more interactive and utilize teaching aids properly, and eventually, they could have an opportunity to better express themselves. Fourth, online real-time learner discussion would be attended by this researcher. Learners would have a discussion in real time in the Internet cafe chat room, and different discussion time would be allocated to each team. This researcher would take part in each team's discussion once or more. Fifth, learners would prepare one or more journal(s) about four-hour Internet cafe learning. They have to make it twice a week at least, and it would be a good opportunity for learners to look back on themselves and their teams, and their learning effect would be greater. Specific rules were presented to help them make a successful self-examination. Sixth, there are some spaces in the lower part of objective test sheets to have students describe why they make a particular answer choice. They would be asked to depict the reason of their prior evaluation and lecture assessment especially because their responses would be important for more successful discussion and feedback. Seventh, problem-solving approach was designed to attain learning objectives, stimulate the creative thinking of learners and help them share a more systematic discussion. That would serve as a secondhand guide not to make them digress when they discuss by using information they acquire from a scenario presented in class.

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The Effect of Delayed Compaction on Unconfined Compressive Strength of Soil-Cement Mixtures (지연다짐이 Soil-Cement의 압축강도에 미치는 영향)

  • 정일웅;김문기;도덕현
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.28 no.4
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    • pp.66-76
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    • 1986
  • This study was attempted to investigate the effects of delayed compaction on the unconfined compressive strengh and dry density of Soil-cement mixtures. Soil-cement construction is a time-consuming procedure. Time-delay is known as a detrimental factor to lower the quality of soil-cement layer. A laboratory test was performed using coarse and fine weathered granite soils. The soils were mixed with 7% cement at optimum moisture content and excess moisture content in part. Socondary additives such as lime, gypsum-plaster, flyash and sugar were tried to counteract the detri-mental effect of delayed compaction. The specimens were compacted by Harvard Miniature Compaction Apparatus at 0,1,2,4,6 hors after mixing. Two kinds of compactive efforts(9 kgf and 18 kgf tamper) were applied. The results were summarized as follows: 1.With the increase of time delay, the decrease rate of dry density of the specimen compacted by 9 kgf tamper was steeper than that of the specimen compacted by 18kgf tamper. In the same manner, soil-B had steeper decreasing rate of dry density than soil-A. 2.Based on the results of delayed compaction tests, the dry density and unconfined compressive sterngth were rapidly decreased in the early 2 hours delay, while those were slowly decreased during the time delay of 2 to 6 hours. 3.The dry density and unconfined compressive strength were increased by addition of 3% excess water to the optimum moisture content during the time delay of 2 to 6 hours. 4.Without time delay in compaction, the dry densities of soil-A were increased by adding secondary additives such as lime, gypsum-plaster, flyash and sugar, on the other hand, those of soil-B were decreased except for the case of sugar. 5.The use of secondary additives like lime, gypsum-plaster, flyash and sugar could reduce the decrease of unconfined compressive strength due to delayed compaction. Among them, lime was the most effective. 6.From the above mentioned results, several recommendations could be suggested in order to compensate for losses of unconfined compressive strenght and densit v due to delayed compaction. They are a) to use coarse-grained granite soil rather than fined-grained one, b) to add about 3% excess compaction moisture content, c) to increase compactive effort to a certain degree, and d) to use secondary additives like line gypsum-plaster, flyash, and sugar in proper quantity depending on the soil types.

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Automatic Detection of Usability Issues on Mobile Applications (모바일 앱에서의 사용자 행동 모델 기반 GUI 사용성 저해요소 검출 기법)

  • Ma, Kyeong Wook;Park, Sooyong;Park, Soojin
    • KIPS Transactions on Software and Data Engineering
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    • v.5 no.7
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    • pp.319-326
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    • 2016
  • Given the attributes of mobile apps that shorten the time to make purchase decisions while enabling easy purchase cancellations, usability can be regarded to be a highly prioritized quality attribute among the diverse quality attributes that must be provided by mobile apps. With that backdrop, mobile app developers have been making great effort to minimize usability hampering elements that degrade the merchantability of apps in many ways. Most elements that hamper the convenience in use of mobile apps stem from those potential errors that occur when GUIs are designed. In our previous study, we have proposed a technique to analyze the usability of mobile apps using user behavior logs. We proposes a technique to detect usability hampering elements lying dormant in mobile apps' GUI models by expressing user behavior logs with finite state models, combining user behavior models extracted from multiple users, and comparing the combined user behavior model with the expected behavior model on which the designer's intention is reflected. In addition, to reduce the burden of the repeated test operations that have been conducted by existing developers to detect usability errors, the present paper also proposes a mobile usability error detection automation tool that enables automatic application of the proposed technique. The utility of the proposed technique and tool is being discussed through comparison between the GUI issue reports presented by actual open source app developers and the symptoms detected by the proposed technique.

Determination of Dynamic Modulus of cold In-place Recycling Mixtures with Foamed Asphalt (폼드아스팔트를 이용한 현장 상온 재생 아스팔트 혼합물의 동탄성계수 결정)

  • Kim, Yong-Joo Thomas;Lee, Ho-Sin David
    • International Journal of Highway Engineering
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    • v.11 no.1
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    • pp.1-12
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    • 2009
  • A new mix design procedure for cold in-place recycling using foamed asphalt (CIR-foam) has been developed for Iowa Department of Transportation. Some strengths and weaknesses of the new mix design parameters were considered and modified to improve the laboratory test procedure. Based on the critical mixture parameters identified, a new mix design procedure was developed and validated to establish the properties of the CIR-foam mixtures. As part of the validation effort to evaluate a new CIR-foam mix design procedure, dynamic moduli of CIR-foam mixtures made of seven different reclaimed asphalt pavement (RAP) materials collected throughout the state of Iowa were measured and their master curves were constructed. The main objectives of this study are to provide: 1) standardized testing procedure for measuring the dynamic modulus of CIR-foam mixtures using new simple performance testing (SPT) equipment; 2) analysis procedure for constructing the master curves for a wide range of RAP materials; and 3) impacts of RAP material characteristics on the dynamic modulus. Dynamic moduli were measured at three different temperatures and six different loading frequencies and they were consistent among different RAP sources. Master curves were then constructed for the CIR-foam mixtures using seven different RAP materials. Based upon the observation of the constructed master curves, dynamic moduli of CIR-foam mixtures were less sensitive to the loading frequencies than HMA mixtures. It can be concluded that at the low temperature, the dynamic modulus is affected by the amount of fines in the RAP materials whereas, at the high temperature, the dynamic modulus is influenced by the residual binder characteristics.

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