• Communications for Statistical Applications and Methods
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• v.31 no.5
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• pp.571-584
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• 2024

To identify differentially expressed genes (DEGs), researchers use a testing method for each gene. However, microarray data are often characterized by large dimensionality and a small sample size, which lead to problems such as reduced analytical power and increased number of tests. Therefore, we propose a clustering method. In this method, genes with similar expression patterns are clustered, and tests are conducted for each cluster. This method increased the sample size for each test and reduced the number of tests. In this case, we used a nonparametric permutation test in the proposed method because independence between samples cannot be assumed if there is a relationship between genes. We compared the accuracy of the proposed method with that of conventional methods. In the simulations, each method was applied to the data generated under a positive correlation between genes, and the area under the curve, power, and type-one error were calculated. The results show that the proposed method outperforms the conventional method in all cases under the simulated conditions. We also found that when independence between samples cannot be assumed, the non-parametric permutation test controls the type-one error better than the t-test.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.100-103
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• 2010

Purpose: $^{18}F$-FDG wholebody PET is to evaluate the tumor using glucose metabolism. The blood glucose level is important factor that affects on a result of examination. High glucose levels may interfere with tumor targeting due to competitive inhibition of FDG uptake by D-glucose. The blood glucose level measurement test strips used in the blood glucose measurement are classified into the capillary blood measurement test strips and general purpose measurement test strips that can measure the venous blood and capillary blood altogether depends on cases. The purpose of the study was to compare the blood glucose measurements between simultaneously obtained capillary and venous blood samples using the capillary blood measurement test strips, general purpose measurement test strips. Materials and Methods: A total of 46 subjects (32 males, 14 females) with a mean age of $57.3{\pm}12.3$ years were enrolled. The blood glucose estimation was performed with a Optium Xceed Glucometer (Abbott). Simultaneous capillary and venous blood samples were obtained from each subject. The blood glucose levels were measured using the capillary blood measurement test strips and general purpose measurement test strips. The capillary and venous measurements were compared using a pared t-test. Results: The mean capillary and venous glucose values using the general purpose measurement test strips were $95.2{\pm}12.4$ mg/dL and $104.1{\pm}14.4$ mg/dL, giving a statistically significant difference (p<0.001) between the mean values for the capillary and venous glucose samples (9.0 mg/dL; 95% confidence interval (CI) -11.2 to -6.7). The mean capillary and venous glucose values using the capillary blood measurement test strips were $91.5{\pm}13.6$ mg/dL and $108.6{\pm}16.2$ mg/dL, giving a statistically significant difference (p<0.001) between the mean values for the capillary and venous glucose samples (16.6 mg/dL; 95% CI -20.2 to -13.0). Conclusion: When measuring the blood glucose level before $^{18}F$-FDG PET examination, since the incorrect blood glucose level can be measured, it should note to measure the blood glucose level of the venous blood by the capillary blood measurement test strips. Therefore the measurement variation can be reduced to fulfill the standardized measurement procedure with the suitable measurement test strips, the preparation of the PET examination will be able to be clearly confirmed. In addition, the standardized procedure of the following measurement on the area which is same at all times the blood area in the blood glucose measurement among a capillary or a vein will be needed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.3
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• pp.80-94
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• 2009

Objective : The purpose of this clinical research is the investigation of the effects between acupuncture group(control group) and NURIEYE-1 group (experimental group) in myopia Methods : Comparison clinical study was conducted with the randomly arranged 32 patients for acupuncture group(control group) and NURIEYE-1 group(experimental group). For effectiveness evaluation, eye sight test, MQOL and DITI were tested three times with visits for every 4 weeks. With SAS, Statistical analysis was performed by using paired t-test and two sample t-test. Statistical significance was achieved with less than 5% probability (p<0.05). Result : 1. There was no significant effect from the eye sight comparison between the two group. We had improved results in average with MQOL, however, there was no statistical significance. Though there was also no significant result with DITI average comparison between two group, we witnessed significant effect in some part of MQOL. 2. Nevertheless Periodical comparison test showed weak significance with eye sight and DITI, significant effect was found in some part of MQOL. 3. With periodical comparison tests, there were significant effects in eye sight, MQOL and DITI with the experimental groups and control groups, respectively. Conclusion : There was no significant eye sight improvement. However, with acupuncture point stimulation, we think there are some positive effects for the relaxation of excessive stress in eyes.

• Journal of Convergence for Information Technology
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• v.10 no.9
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• pp.62-70
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• 2020

The purpose of this study was to investigate the degree of social support, career decision-making self-efficacy, and Job-Seeking Stress of nursing students, and identify influencing factors of Job-Seeking Stress. A convenience sample of 228 nursing students was conducted from in three departments of nursing. Data were analyzed through descriptive statistics, t-test, ANOVA, Scheffe test, Pearson's correlation coefficient, and multiple regression analysis using IBM SPSS 21.0 program. The higher the social support and career decision self-efficacy, the lower the Job-Seeking Stress. The factors influencing Job-Seeking Stress were social support, first hope career, job readiness, career decision-making self-efficacy, and the explanatory power of these variables for Job-Seeking Stress was 19%. Therefore, in order to prevent, cope with, and mitigate the Job-Seeking Stress of nursing students, it is necessary to develop and apply differentiated Career education programs to increase social support and career decision-making self-efficacy.

• Journal of Digital Convergence
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• v.16 no.9
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• pp.219-228
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• 2018

The purpose of this study was to examine the influence of ethical values and ethical sensitivity on character in junior and senior nursing students. A total of 356 surveys were analyzed using SPSS version 20. T-test, ANOVA/Kruskal-Wallis test, Pearson correlation coefficients, and stepwise multiple regression analysis were used. The results of the study showed that the main factors influencing character was patient oriented care in ethical sensitivity (${\beta}=0.258$), followed by nurse-colleague relationship among ethical values (${\beta}=0.153$), religion (${\beta}=0.131$), professional responsibility in the ethical sensitivities (${\beta}=0.101$), and the above variables accounted for 43.3% of character (F=44.960, p<.001). This study confirmed that ethical values and ethical sensitivity are important variables affecting character and convergence course integrating above factors needs to be provided for nursing students.

• Journal of the Korea Convergence Society
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• v.7 no.6
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• pp.275-285
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• 2016

The purpose of this study is to identify the factors influencing on the burden on the family caregivers of patient with more than second degree burn. The participants of this study were 120 family caregivers sampled for convenience from 4 Burn hospitals in D, S, B, P cities in South Korea. Data analysis was performed by t-test, ANOVA, Scheffe' test, Multiple linear regression. According to the result, the burden of assess & mean of care and the future of the patient was the highest score for family caregivers. Factors that affect the burden of family caregiver with burn patients were marital status, time, care, skin transplants, body surface area (%) and these factors explained 25.9%. This study concludes that intervention program is developed to reduce physical and emotional burden and nursing care services is required to adjust the amount time to care for the family caregivers with burn patients for a long time.

• Journal of Digital Convergence
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• v.16 no.8
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• pp.401-411
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• 2018

The purpose of this study was to investigate appearance concern, attitude toward cosmetic surgery, self-esteem, quality of life, and to identify affecting factors of quality of life on elderly women. The subjects consisted of 162 elderly women in the G city. The variables were measured using questionnaires, analyzed using descriptive statistic, ${\chi}^2-test$, t-test, ANOVA, Pearson correlation coefficient, and multiple regression analysis. The appearance concern, attitude toward cosmetic surgery were not significant difference in 60s and 70s. Quality of life was significant difference in 60s and 70s. Factors influencing quality of life in 60s were self-esteem, perceived health status, and explanation of quality of life is 39.1%. In 70s were self-esteem, level of education, and explanation of quality of life is 41.7%. These results suggest that it is necessary for aging preparation education included appearance concern and should be made to develop program to improve quality of life.

• Journal of Digital Convergence
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• v.13 no.12
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• pp.347-357
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• 2015

The purpose of this study was to identify the relationship between nurses' spirituality and attitude toward terminal and to provide basic data for enhancement of the quality of terminal care in geriatric hospitals. Data analysis was done with SPSS/WIN 18.0 program and included t-test, ANOVA, scheffe test, Pearson's Correlation Coefficient. Results: The subjects' spirituality was significantly correlated with attitude toward terminal care in geriatric hospital. Conclusion: This study suggests the need for nursing education program and development of a variety of intervention strategies to help them to achieve a positive attitude toward terminal care in terms of geriatric hospital by familiarizing themselves with the concept of spirituality.

• Convergence Security Journal
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• v.16 no.3_1
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• pp.69-75
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• 2016

This study a Empirical research to examine the relationships among Coaching leadership, Directive leadership, Self-Efficacy and Cohesion, On the focus of Marine Corps Soldiers. The data was collected from 370 Soldiers located at Pohang, January 18 to 25, 2016. Descriptive statistics, frequency, t-test, ANOVA, scheffe test, and Pearson correlation analysis were performed using SPSS/WIN 22.0 program. In Cohesiveness, there were significants differences in Age, Branch of Service and Rank. As the result of Pearson' correlation, the relationships between leadership style, Self-efficacy and Cohesion were positive significants. The implications of these findings for effective leradership of Platoon Leader and future research on develop leradership program and curriculum were then discussed.

• Journal of Sensor Science and Technology
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• v.16 no.1
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• pp.17-23
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• 2007

This paper presents a miniaturized turn-counting sensor (TCS) where the geomagnetism and high-rpm rotation of ammunition are used to detect the turn number of ammunition for applications to small-caliber turn-counting fuzes. The TCS, composed of cores and a coil, has a robust structure with no moving part for increasing the shock survivability in the gunfire environments of ${\sim}30,000$ g's. The TCS is designed on the basis of the simulation results of an electromagnetic analysis tool, $Maxwell^{(R)}$3D. In experimental study, the static TCS test using a solenoid-coil apparatus and the dynamic TCS test (firing test) have been made. The presented TCS has shown that the induction voltage of $6.5{\;}mV_{P-P}$ is generated at the magnetic flux density of 0.05 mT and the rotational velocity of 30,000 rpm. From the measured signal, the TCS has shown the SNR of 44.0 dB, the nonlinearity of 0.59 % and the frequency-normalized sensitivity of $0.26{\pm}0.01{\;}V/T{\cdot}Hz$ in the temperature range of $-30{\sim}+43^{\circ}C$. Firing test has shown that the TCS can be used as a turn-counting sensor for small-caliber ammunition, verifying the shock survivability of TCS in high-g environments.