• Title/Summary/Keyword: Synthetic population

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Anticonvulsant potential of some medicinal plants and their beneficial properties

  • Asif, Mohammad
    • CELLMED
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    • v.3 no.4
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    • pp.27.1-27.13
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    • 2013
  • Epilepsy has now become the most serious brain disorder. A number of synthetic antiepileptic drugs are available in practice, however their effectiveness does not grip true with the entire population suffering from epilepsy. Traditional systems of medicine are popular in developing countries and most of the population relies on traditional medicines for their primary health care need. Medicinal plants to be an important source of traditional medicines. Various plants are used for the treatment of epilepsy in traditional system of medicines and various plants are yet to be scientifically investigated. Phytoconstituents have been the basis of treatment of human diseases including epilepsy. Herbal products are extensively used for the treatment of many diseases worldwide and where allopathic fails or has severe side effects. Psycho neural drugs are also have very serious side effects like physical dependence, tolerance, deterioration of cognitive function and effect on respiratory, digestive and immune system. So the treatments through herbal medicines are widely used across the world due to their wide applicability and therapeutic efficacy with least side effects, which in turn has accelerated the research regarding natural therapy. In this review we have summarized some herbal antiepileptics.

Star formation history of infrared luminous galaxies in the SDSS

  • Lee, Jong-Chul;Lee, Myung-Gyoon;Hwang, Ho-Seong
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.1
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    • pp.60.1-60.1
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    • 2011
  • We present preliminary results of a statistical study on star formation history of infrared luminous galaxies selected from a IRAS-SDSS matched sample. We derive their star formation histories by comparing observed optical spectra and stellar population synthetic model templates. We find that young population fraction (<500 Myr) increases with infrared luminosity, while AGN-host (based on optical line ratios) galaxies show an enhancement of star formation at intermediate age (around 1 Gyr) compared with starburst galaxies. These results support that infrared luminosity is dominated by starburst activity and that there is an evolutionary connection from starburst to AGN.

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Genomic Barcode-Based Analysis of Exoelectrogens in Wastewater Biofilms Grown on Anode Surfaces

  • Dolch, Kerstin;Wuske, Jessica;Gescher, Johannes
    • Journal of Microbiology and Biotechnology
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    • v.26 no.3
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    • pp.511-520
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    • 2016
  • The most energy-demanding step of wastewater treatment is the aeration-dependent elimination of organic carbon. Microbial fuel cells (MFCs) offer an alternative strategy in which carbon elimination is conducted by anaerobic microorganisms that transport respiratory electrons originating from carbon oxidation to an anode. Hence, chemical energy is directly transformed into electrical energy. In this study, the use and stability of barcode-containing exoelectrogenic model biofilms under non-axenic wastewater treatment conditions are described. Genomic barcodes were integrated in Shewanella oneidensis, Geobacter sulfurreducens, and G. metallireducens. These barcodes are unique for each strain and allow distinction between those cells and naturally occurring wild types as well as quantification of the amount of cells in a biofilm via multiplex qPCR. MFCs were pre-incubated with these three strains, and after 6 days the anodes were transferred into MFCs containing synthetic wastewater with 1% wastewater sludge. Over time, the system stabilized and the coulomb efficiency was constant. Overall, the initial synthetic biofilm community represented half of the anodic population at the end of the experimental timeline. The part of the community that contained a barcode was dominated by G. sulfurreducens cells (61.5%), while S. oneidensis and G. metallireducens cells comprised 10.5% and 17.9%, respectively. To the best of our knowledge, this is the first study to describe the stability of a synthetic exoelectrogenic consortium under non-axenic conditions. The observed stability offers new possibilities for the application of synthetic biofilms and synthetically engineered organisms fed with non-sterile waste streams.

Evaluation of Crossbreeding Effects for Wool Traits in Sheep

  • Malik, B.S.;Singh, R.P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.11
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    • pp.1536-1540
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    • 2006
  • Crossbreeding effects for wool quality traits viz. greasy fleece weight (kg), staple length (cm), average fibre diameter (${\mu}$) and medulation percentage were estimated using the Dickerson's and Kinghorn's models. The data analyzed involved 15 genetic groups including Nali purebred, $F_1$'s of two and three breeds, $F_2$'s and reciprocal crossbred obtained from the crossing of Nali (N), Merino (M) and Corriedale (C) breeds during 1980-96. Nali and Corriedale breeds had non-significant negative additive genetic effects (Dickerson's model) on greasy fleece weight, while effects of Corriedale were negative for staple length only from both models. In general additive genetic effects of all three breeds were non-significant for all the wool traits except medulation percentage. Non significant heterotic and recombination effects (epistatic loss) were estimated from both models. However, the estimates of crossbreeding effects varied between the models both in magnitude as well as in direction barring few exceptions. Undesirable positive heterosis was found on medulation percentage for all types of combinations involving three breeds. Comparison of least squares means of various genetic groups revealed that both two breed and three breed crosses were superior to the Nali breed for all wool quality traits. Fibre diameter of MN crossbreds was significantly less than CN crossbreds. Results also indicated that as the inheritance of Nali breed in a cross is decreased, the medulation percentage decreases which is desirable. Inter se mating of crossbreds (two breed, three breed) has not resulted in a decline in the wool quality traits. These results indicate that the synthetic population derived from three breeds can be stabilized easily for wool traits as there may not be epistatic loss on subsequent inter se mating of crossbreds.

Control of Green Peach Aphid (Myzus Persicae) by Combination of Plant Oil Formulations and Low-dosed Imidacloprid

  • Yang, You Ri;Kim, Seon-Hwa;Park, Myung-Ryeol;Kim, Ik-Soo;Kim, In-Seon
    • Korean Journal of Environmental Agriculture
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    • v.29 no.3
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    • pp.239-246
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    • 2010
  • Aphids are one of the major pests in agricultural crops. A number of synthetic pesticides have been used for control of aphids in agriculture, but increasing public concerns over their adverse effects on the environment have required more environmentally-friendly methods for pest management. In this study, we examined plant oil formulations for the control of green peach aphid (Myzus persicae). Oil formulations were prepared by hydrolyzing the plant oils in ethanolic KOH solution and diluted at the rate of 1:500 for aphid control. The oil formulations showed aphid mortalities ranging from 24.44 to 43.33% in vitro. Significantly increased aphid mortalities were observed by the treatment of oil formulations combined with low-dosed imidacloprid. No significant difference in the aphid mortality was observed between the oil formulations. Mass spectrometry analyses of aphids treated with the low dosedimidacloprid plus the plant oil formulations detected similar concentrations of imidacloprid between the treatments. In field trial bioassays against aphids, significantly decreased aphid population were observed in the pepper plants treated with soybean oil formulation combined with the low-dosed imidacloprid, while aphid population dramatically increased in the pepper plants treated with the low-dosed imidacloprid alone. These results suggested that the plant oil formulations can be used as an environmentally-friendly method for enhancing the insecticidal effectiveness, which may play a role in reducing the use of synthetic pesticide in agriculture.

Design-Based Small Area Estimation for the Korean Economically Active Population Survey (시군구 실업자 총계 추정을 위한 설계기반 간접추정법)

  • 정연수;이계오;이우일
    • The Korean Journal of Applied Statistics
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    • v.16 no.1
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    • pp.1-14
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    • 2003
  • In this study, we suggest the method of small area estimation based on the Economically Active Population Survey (EAPS) data in producing unemployment statistics for the local self-government areas (LSGAs) within large areas. The small area estimators considered are design-based indirect estimators such as the synthetic and composite estimators. The jackknife mean square error was used as a measure of accuracy of such small area estimators. The total unemployed and jackknife mean square errors of the 10 LSGAs within the large area of ChoongBuk region are derived from the estimation procedure suggested in this study, using EAPS data of December 2000. The reliability of small area estimators was assessed using the relative bias values and relative root mean square errors of these estimators. We find that under the current Korean EAPS system, the composite estimator turns out to be much more stable than other estimators.

Entity Embeddings for Enhancing Feasible and Diverse Population Synthesis in a Deep Generative Models (심층 생성모델 기반 합성인구 생성 성능 향상을 위한 개체 임베딩 분석연구)

  • Donghyun Kwon;Taeho Oh;Seungmo Yoo;Heechan Kang
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.22 no.6
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    • pp.17-31
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    • 2023
  • An activity-based model requires detailed population information to model individual travel behavior in a disaggregated manner. The recent innovative approach developed deep generative models with novel regularization terms that improves fidelity and diversity for population synthesis. Since the method relies on measuring the distance between distribution boundaries of the sample data and the generated sample, it is crucial to obtain well-defined continuous representation from the discretized dataset. Therefore, we propose an improved entity embedding models to enhance the performance of the regularization terms, which indirectly supports the synthesis in terms of feasible and diverse populations. Our results show a 28.87% improvement in the F1 score compared to the baseline method.

A comparison between the real and synthetic cohort of mortality for Korea (가상코호트와 실제코호트 사망력 비교)

  • Oh, Jinho
    • The Korean Journal of Applied Statistics
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    • v.31 no.4
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    • pp.427-446
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    • 2018
  • Korea will have a super-aged society within only 30 years according to the United Nations' definition of an aging society and the statistics on Korea's Population projections (2016), indicates that Korea has the fastest ageing speed in the world. There is a lack of data on long-term time-series data on death as related to pension and welfare policies compared to the rapid rate of aging. This paper estimates life expectancy over 245 years (from 1955 to 2200) through past and future forecasts as well as compares the expected life expectancy of the synthetic cohort and the real cohort. In addition, an international comparisons were made to understand the level of aging in Korea. Estimates of the back-projection period were compared with previous studies and the LC model to improve accuracy and objectivity. In addition, the predictions after 2016 reflected the declined mortality rate effect of Korea using the LC-ER model. The results showed an increase in life expectancy of about 30 years over 60 years (1955-2015) with an expected life expectancy of the real cohort over the second century (1955-2155) higher than the synthetic cohort. The comparative advantage of life expectancy of real cohorts was confirmed to be a common trend among comparative countries. In addition, Japan and Korea have a higher life expectancy and starting from 85 to 90 years old, all comparative countries show that the growth rate for the life expectancy of synthetic and real cohorts is less than previous years.

Globular clusters with multiple red giant branches: Population synthesis models

  • Joo, Seok-Joo;Lee, Young-Wook;Na, Chongsam;Han, Sang-Il
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.75-75
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    • 2013
  • Recent observations have shown that some massive globular clusters (GCs) host multiple stellar populations having different heavy element abundances enriched by supernovae. They usually accompany multiple red giant branches (RGBs) in the color-magnitude diagrams (CMDs), and are distinguished from most of the other GCs which display variations only in light element abundances. In order to investigate the star formation histories of these peculiar GCs, we have constructed synthetic CMDs based on the updated versions of Yonsei.Yale ($Y^2$) isochrones and horizontal branch evolutionary tracks which include the cases of enhancements in both helium and the total CNO abundances. To estimate ages and helium abundances of subpopulations in each GC, we have compared our models with the observations on the Hess diagram by employing a ${\chi}^2$ minimization technique. In this talk, we will present our progress in the population modeling for these GCs with multiple RGBs.

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Biological Control Strategy of Uzi Fly in Sericulture

  • Singh, R.N.;Saratchandra, Beera
    • International Journal of Industrial Entomology and Biomaterials
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    • v.6 no.2
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    • pp.125-132
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    • 2003
  • Uzi fly (Exorista bombycis Louis) is one of the major larval endo-parasitoid of silkworm (Bombyx mori). It causes extensive damage to sericulture industry. The application of synthetic organic pesticides has tremendous impact on minimizing pest population but their overuse and frequent misuse and high sensitivity towards the silkworms, has forced the entomologists to search for alternatives to chemical control, which is safe to silkworm, environment and farm workers. Biological control continues to offer exciting possibilities for the control of fly pest population. It is environmentally safe alternative to chemical control and offering a long-term protection. Several potential hymenopteran parasitoids have been screened. Among successful natural enemies, Nesolynx thymus, Trichomalopsis apanteloctena, Trichopria sp., Brachymeria lasus, Pediobius sp., Spalangia sp., Spilomicrus karnatakensis and Dhirhinus sp. are important. It is essential to predict accurately the efficacy of these natural enemies in a new habitat prior to its introduction. The important desirable attributes of these potential parasitoids viz., host searching capacity, specificity, power of increase and fitness and adaptability of the parasitoid in new environment has been recorded. Results of the host parasitoid interaction indicate that the aging of the host function as a factor that influence the host finding efficiency of the parasitoid. It is highly scored with 15-20 hrs old pupa of the host. However, aging of the parasitoid does not significantly affect it. The sex ratio is female biased which is advantageous from biological control point of view, Biological suppression methods involving conservation and utilization of natural enemies have been discussed in detail.