• Journal of Ginseng Research
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• v.24 no.1
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• pp.8-17
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• 2000

Estrogen can influence on the expression of behaviors not associated directly with reproduction, including learning and memory. Recently estrogen has received considerable attention for its effects on neuroprotection and neural circuits in brain areas associated with cognition. Although estrogen replacement therapy may be helpful to postmenopausal women, it also results in a number of harmful side effects. Ginseng also has steroidal qualities and contains several ginsenoside components which have similar backbone structure to estrogen. The objectives of this experiment were 1) to examine the effects of estrogen and 2) to investigate the effects of ginsenosides as estrogenic agent on learning and memory using the Morris water maze, a traditional experimental task for spatial memory. In the experiments designed here, ovariectomized mice were implanted subcutaneously with Sila, itic capsules containing 17${\beta}$-estradiol (100∼250 $\mu\textrm{g}$/$m\ell$), panaxadiol (PD) and panaxatriol (PT) saponins (15∼100 $\mu\textrm{g}$/$m\ell$) diluted with sesame oil. In the first set of experiment, the effects of estradiol on learning and memory during the Morris water maze was examined. When estradiol was delivered via Silastic capsules following training improved spatial memory performance in ovariectomized female mice. In the second set of experiment, three different PD and PT saponin concentrations were delivered via Silastic implants to ovariectomized female mice and their effects were compared with estrogenic effects. Results of three separate experiments demonstrated that estradiol, PD and PT administrated by Silastic implants for 2 weeks prior to water maze training significantly improved spatial memory performance compared to ovariectomized (OVX) mice, as indicated by lower escape latency over trial. The positive effect of estradiol suggests that estrogen can affect performance on learning and memory. In addition, the positive effect of PD and PT saponins suggest that ginsenosides have an estrogen-like effects in mediating learning and memory related behavior action.

• Journal of the Korean Institute of Landscape Architecture
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• v.47 no.3
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• pp.60-70
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• 2019

Today, Deoksugung Doldam-gil, which is a well-known area in Seoul, has become a mixed place as many places reaching a critical age have been converted into parks. However, the previous research on the Deoksugung Doldam-gil was deficient in that the user, an essential variable, was not considered when assessing the place. Based on that, this study aims to analyze and interpret the perception of the places in Deoksugung Doldam-gil and to analyze factors to further enrich the place to visitors. According to the research, the representative idea of Deoksugung Doldam-gil is "the distance you want to go" and that has influencing factors, such as vehicle restrictions and the improvement of the walking environment. The analysis of classifying the variables that make up the perception of the place, physical environments, activities and meanings showed high awareness in, "streets of green (3.95)" and "stone walls of curves (3.88)." In the category of activities, "walking activities in the inner city (4.01)" and "love and romance (3.57)" were high. These results seem to reflect the spatial characteristics of the streets and the familiar image of the place were important. Five factors were extracted from the factor analysis to provide a more detailed understanding of the place perception, the correlation between each factor, and the place atmosphere of Deoksugung Doldam-gil. These factors confirmed a high correlation between 'green landscape' and 'historicity.' This can be attributed to the fact that the analysis reflects vital space, visual experience, and free walking conditions to be important, and these variables are present in urban parks. It also indicates the long-accumulated image and behavior near the site of Deoksugung Palace, including the historical and cultural heritage. It was confirmed that the factors related to the cognitive perception of Deoksugung Doldam-gil and the formation of the atmosphere of the place were strongly recognized. It found that there was a need to reflect the value and importance of 'green' in the future as culture or in the use of preservation and management related to heritage. This study presented a direction to be noted from the perspective of a user's place awareness, but considered only a fraction of the variables that affect the multidimensional sense of place and location recognition, and thus must be supplemented in the future.

• The Journal of the Korea Contents Association
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• v.14 no.7
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• pp.529-540
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• 2014

Korea's baby boomers constitute a quarter of the population structure, and they are now faced with super-aged era represented by the life expectancy of 100 years. Since this generation who played a leading role in economic growth of the country has needs for active participation in society and continuous economic activities based on the healthy bodies, sufficient wealth and desires for cultural consumption, it is called 'active seniors' as a new demographic class differentiated from the conventional elder generation. This study was intended to investigate housing needs of baby boomers as preliminary seniors in Seoul with the highest residential density of the baby boomers through a bottom-up process from the perspective of consumers, and to select the findings as criteria for residential complex plans. The analysis results showed that 'social accessibility' was most highly valued among baby boomers in Seoul, and 'medical accessibility' was determined to be the second most important factor. Other items such as 'convenience of living' and 'spatial cognition' were ranked as the least important factors. These findings suggest that the life style of baby boomers in Seoul is very similar to that pursued by active seniors in terms of life cycle, and it is determined to be a characteristic as a niche for housing needs different from the one found in conventional elder generation.

• Cartoon and Animation Studies
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• s.43
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• pp.1-22
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• 2016

So far, the Studio Ghibli's major masterpieces, and have been studied extensively from mythical and psychological perspectives due to the films' intrinsic symbolism within their characters and events. However, there have been insufficient in-depth research on the types of love the two works have. Therefore, this study will focus on how the types of love in the two animations mirror the concept of love in Plato's theory of Eros through the analysis of two films' characters. The desire for memory and recovery can be seen in , and glimpses of each phase of aim towards changes in physical appearance can be shown in . These describe the function and the purpose of Eros that Plato states in Socrates' terms in Phaedrus and Symposium. Plato ultimately defined Eros as a spirit that leads to the world of Ideas and suggested the five stages of love that are divided in accordance with the ultimate purpose and attitude of mankind towards Eros. The cognition area, changes in appearance of the characters and spatial ranks in and critically reveal such core concepts of the theory of Eros. It is noteworthy that the two works show the origin of the most universal ideology of the West. These two animation films are particularly significant in terms of that they reflect the western epistemology while covering exclusive and covert ethnic emotions.

• Education of Primary School Mathematics
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• v.14 no.3
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• pp.237-259
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• 2011

Mathematics learning disabilities is a specific learning disorder affecting the normal acquisition of arithmetic and spatial skills. Reported prevalence rates range from 5 to 10 percent and show high rates of comorbid disabilities, such as dyslexia and ADHD. In this study, the characteristics and the causes of this disorder has been examined. The core cause of mathematics learning disabilities is not clear yet: it can come from general cognitive problems, or disorder of innate intuitive number module could be the cause. Recently, researchers try to subdivide mathematics learning disabilities as (1) semantic/memory type, (2) procedural/skill type, (3) visuospatial type, and (4) reasoning type. Each subtype is related to specific brain areas subserving mathematical cognition. Based on these findings, the author has performed a basic research to develop grade specific diagnostic tests: number processing test and math word problems for lower grades and comprehensive math knowledge tests for the upper grades. The results should help teachers to find out prior knowledge, specific weaknesses of students, and plan personalized intervention program. The author suggest diagnostic tests are organized into 6 components. They are number sense, conceptual knowledge, arithmetic facts retrieval, procedural skills, mathematical reasoning/word problem solving, and visuospatial perception tests. This grouping will also help the examiner to figure out the processing time for each component.

• Journal of the Korean association of regional geographers
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• v.21 no.2
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• pp.286-303
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• 2015

This paper aims at analyzing the role of Korean ethnic network in the settlement process of Korean immigrants, and elucidating their utilization measures, through the case Study of Korean Immigrants in LA. The main results of this study are as follows. Firstly, the majority of respondents used Korean ethnic networks and Korean town in the immigration process. According to the results of ANOVA test, Korean ethnic network are more importantly considered by the groups such as elderly, livers in Korean town, and people who the first settlement was LA. Secondly, respondents more frequently use Korean ethnic network in the activities such as church, shopping and business. Especially, the groups such as short immigration term, elderly, poor English ability are more frequently use Korean ethnic network. Thirdly, Viewing the cognition of respondents about the necessity of Korean ethnic networks, respondents want to use them for strengthening the ties of domination society. Finally, utilization of Korean ethnic churches, Korean ethnic business organizations and Korean ethnic web-site portal are proposed for activating Korean ethnic networks.

• Journal of the Economic Geographical Society of Korea
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• v.12 no.4
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• pp.364-387
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• 2009

Female marriage immigrants have increased since the mid-1990s in Korea. Thus, their adaptation to Korean society has been a big social issue in Korea. There are a lot of academic researches on their adaptation to Korean society so far. We cannot sufficiently understand general main factors of their adaptation to Korean society because of methodological problems in the studies on the female marriage immigrants. Particularly, there are very few studies on female marriage immigrants' adaptation to their communities. This study analyzes determinants of female marriage immigrants' adaptation to their communities, using stepwise multi-regression. Data are collected from questionary survey on female marriage immigrants in Seoul, Gyeong-gi, Daegu, Gyeong-buk, Gwangju, Jeon-nam. Dependent variables are community life, spatial cognition and activities, and neighborhood relationship. Each dependent variable is analyzed with 30 independent variables through stepwise multi-regression. As a result, 16 positive determinants and 2 negative ones are selected. Positive determinants are resident identity, age, adaptation to home, number of Korean friends and same nationals' friends in Korea and so on. But, Korean language fluence is not selected as a significant factor. This is different from a general recognition. As exiting researches, the importance of social network and adaptation variables is also identified in this study.

• Journal of Applied Biological Chemistry
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• v.64 no.3
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• pp.299-307
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• 2021

Accumulation of amyloid beta (Aβ) and oxidative stress are the most common reason of Alzheimer's disease (AD). In the present study, we investigated the cognitive improvement effects of butanol (BuOH) fraction from Momordica charantia in Aβ_25-35-induced AD mouse model. To develop an AD mouse model, mice were received injection of Aβ_25-35, and then orally administered BuOH fraction from M. charantia at doses of 100 and 200 mg/kg/day during 14 days. In the T-maze and novel object recognition test, administration of BuOH fraction from M. charantia L. at doses of 100 and 200 mg/kg/day improved spatial ability and novel object recognition by increased explorations of novel route and new object. In addition, BuOH fraction of M. charantia-administered groups improved learning and memory abilities by decreased time to reach hidden platform in Morris water maze test. Oral administration of BuOH fraction from M. charantia significantly inhibited lipid peroxidation and nitric oxide levels in the brain, liver, and kidney compared with Aβ_25-35-induced control group. These results indicated that BuOH fraction of M. charantia improved Aβ_25-35-induced cognitive impairment by attenuating oxidative stress. Therefore, M. charantia could be useful for protection from Aβ_25-35-induced cognitive impairment.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.36 no.6
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• pp.469-481
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• 2018

DL (Deep Learning) is getting popular in various fields to implement artificial intelligence that resembles human learning and cognition. DL based on complicate structure of the ANN (Artificial Neural Network) requires computing power and computation cost. Variety of DL models with improved performance have been developed with powerful computer specification. The main purpose of this paper is to detect buildings from aerial images and evaluate performance of Mask R-CNN (Region-based Convolutional Neural Network) developed by FAIR (Facebook AI Research) team recently. Mask R-CNN is a R-CNN that is evaluated to be one of the best ANN models in terms of performance for semantic segmentation with pixel-level accuracy. The performance of the DL models is determined by training ability as well as architecture of the ANN. In this paper, we characteristics of the Mask R-CNN with various types of the images and evaluate possibility of the generalization which is the ultimate goal of the DL. As for future study, it is expected that reliability and generalization of DL will be improved by using a variety of spatial information data for training of the DL models.

• Sleep Medicine and Psychophysiology
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• v.12 no.2
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• pp.122-132
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• 2005

Objectives: The objective of this study is to assess cognitive functions and their relationship with sleep symptoms in young narcoleptic patients. Methods: Eighteen young narcolepsy patients and 18 normal controls (age: 17-35 years old) were recruited. All narcolepsy patients had HLA $DQB_1$ *0602 allele and cataplexy. Several important areas of cognition were assessed by a battery of neuropsychological tests consisting of 13 tests: executive functions (e.g. cognitive set shifting, inhibition, and selective attention) through Wisconsin card sorting test, Trail Making A/B, Stroop test, Ruff test, Digit Symbol, Controlled Oral Word Association and Boston Naming Test; alertness and sustained attention through paced auditory serial addition test; verbal/nonverbal short-term memory and working memory through Digit Span and Spatial Span; visuospatial memory through Rey-Osterrieth complex figure test; verbal learning and memory through California verbal learning test; and fine motor activity through grooved pegboard test. Sleep symptoms in narcolepsy patients were assessed with Epworth sleepiness scale, Ullanlinna narcolepsy scale, multiple sleep latency test, and nocturnal polysomnography. Relationship between cognitive functions and sleep symptoms in narcolepsy patients was also explored. Results: Compared with normal controls, narcolepsy patients showed poor performance in paced auditory serial addition (2.0 s and 2.4 s), digit symbol tests, and spatial span (forward)(t=3.86, p<0.01; t=-2.47, p=0.02; t=-3.95, p<0.01; t=-2.22, p=0.03, respectively). There were no significant between-group differences in other neuropsychological tests. In addition, results of neuropsychological test in narcolepsy patients were not correlated with Epworth sleepiness scale score, Ullanlinna narcolepsy scale score and sleep variables in multiple sleep latency test or nocturnal polysomnography. Conclusion: The current findings suggest that young narcolepsy patients have impaired attention. In addition, impairment of attention in narcolepsy might not be solely due to sleep symptoms such as excessive daytime sleepiness.