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Acute toxicity, Dermal and Ocular Irritation Studies of Taglisodog-eum ointment (탁리소독음 피부외용제형의 급성경피독성시험, 피부자극시험 및 안점막자극시험)

  • Lee, Jung Bok;Choi, Jae Hwan;Kim, Hee Taek;Kim, Yun Kyung;Yu, Young Beob
    • Herbal Formula Science
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    • v.24 no.4
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    • pp.289-300
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    • 2016
  • Objectives : Taglisodog-eum(TSE), a poly herbal formula, has been widely used to improve carbuncles by removing inflammation of the lymphatic channels in Traditional Korean Medicine. We previousely reported the action mechanism of TSE on experimental atopic dermatitis and the establishment of formulation for TSE ointment. In this study, we examined the toxicity test on skin and eye irritation by TSE ointment to prove the safety of Taglisodog-eum ointment in clinical use. Methods : Acute skin toxicity of the TSE ointment was evaluated in Sprague-Dawley(SD) rats. After dermal administration of TSE ointment(2,000mg/kg), body weight, mortality, and clinical signs of the rats were observed for 14days. Primary skin irritation and ocular irritation tests for TSE ointment were performed in male New Zealand White Rabbits. In dermal and ocular irritation test, body weight, mortality, clinical signs, Primary Irritation Index(P.I.I.), and The Index of Acute Ocular Irritaion(I.A.O.I.) of rabbit were observed after applying at abraded skin and eye balls with Taglisodog-eum ointment. Results : In the results of acute skin toxicity, no significant differences were found in body weight, the clinical sign and the mortality between control and TSE ointment treated group. In primary dermal irritation test, body weight, the clinical sign and the mortality were not significantly changed and Primary Irritation Index(P.I.I.) was 0.8, indicating TSE ointment as weak irritant material. In ocular irritation test, The Index of Acute Ocular Irritaion was 0.0, indicating TSE ointment as non-irritating to the eye of the rabbits. To evaluate toxicity of the TSE ointment in animal test, body weight, the clinical signs, the skin and eye irritation check were conducted; TSE ointment was considered to be weak dermal irritant in test animals. The no response of eye irritation test was observed in this experimental condition. Conclusions : According to the above toxicity test, We consider that this results is helpful for saying about the safety of TSE ointment in clinical use.

Study on Elements influencing on Job Satisfaction of Employees in Hospice and Palliative Care Organization (호스피스.완화의료기관 종사자의 직무만족도에 영향을 미치는 요인에 관한 연구)

  • Lee, Myoung-Hee;Choe, Wha-Sook
    • Korean Journal of Hospice Care
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    • v.7 no.1
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    • pp.15-28
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    • 2007
  • This study was focused on figure out what kinds of elements are influencing on job satisfaction with approach of the educational system. It was also to figure out how work characteristics and role conflicts of employees influence on job satisfaction. Objects of study were employeeswho had been working in Hospice and Palliative medical center at least for 6 months, and they were doctors, nurses, ministers, and welfare workers. Collected materials were analyzed by Frequency Analysis, One-way ANOVA, Correlation Analysis, and SimpleRegression Analysis. Results from study can be summarized like below. The first, job satisfaction of workers in Hospice and Palliative medical center were 3.36, and this numerical value is pretty high over all. For saying from the higher to the lower satisfaction level, there were satisfaction with job itself, satisfaction with co-workers, satisfaction with seniors (superiors), and satisfaction with organizations, on the other hands, satisfaction with salaries was turned out as the lowest level among those. The second, role conflict was 2.63, and it is considered as the medium level. after inquiring into it by elements of role conflict, they felt many environmental difficulties compared to other workers in different fields such as environmental difficulty, role ambiguity, insufficient ability, process obscurity, etc. The third, work environment influencing on job satisfaction are as follows. Professional environment among characteristics of work environment was significant statistically. Job satisfaction of ministers was the highest; others were in the order of doctors, welfare workers, and nurses. For employment history, job satisfaction was higher as they have more and longer job experience including whole professional experience both in hospice and palliative medical center. In addition, participating in hospice and palliative programs, intensive training regularly was significantly. Job Motivation was also significant statistically. Especially, job satisfaction was higher when people decided to work in hospice and palliative medical center because of individual desire (self-realization). Lastly, influence of role conflict on job satisfaction is as follows. Environmental difficulty, role ambiguity, insufficient ability, process obscurity, etc showed the significant meaning statistically, and the lower role conflict was related with the higher job satisfaction. Suggestions for next study based on such results are as follows in order to improve or increase job satisfaction of employees in hospice/palliative medical centers. The first, to expand education opportunity of employees is needed to increase job satisfactionof hospice/palliatives medical centers. Participating in intensive programs and seminars by types of occupation and acquiring professional knowledge are very important since employees are motivated by those activities. For that, developing and activating intensive education/programs by professional occupations are suggested. The second, dividing roles of employees and determining each job's limit clearly in hospice/palliative medical centers are required. For that, study developing standard job regulations is suggested for each professional job. Lastly, developing and providing reasonable salaries is needed because low salaries of hospice/palliative medical centers are the absolute reason lowering job satisfaction. Therefore, this paper suggests improving the salary level of employees of hospice/palliative medical centers and developing practical plan for it.

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Literatual Study on Pathology of Insomnia (불면증(不眠症)의 병인병리(病因病理)에 관한 문헌고찰)

  • Choi Jae-Hong;Lee Dong-Won
    • Journal of Oriental Neuropsychiatry
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    • v.12 no.1
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    • pp.81-95
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    • 2001
  • Though, these days there are increasing many patient of insomnia, there was not considered literatual study on insomnia. So, the result of consideration about cause and process of insomnia from thirty kinds of literatures, are as follows. 1. Early literature like Huangjaenankyung(黃帝內經), Sanghanron(傷寒論) reffered to insomnia as accompanying symptom. on the other hand, Myung(明), Chung(淸)'s literatures reffered to that as chief symptom or distinguished chief symptom from accompanying symptom. 2. There were tendency of deductive expanding of various masters and tendency of induction of simple theory that was based on Huangjaenankyung(黃帝內經). 3. Huangjaenankyung(黃帝內經) showed basic process of the sleep disorder that 'exhausting of Yin and excess of Yang (陰盡陽盛)', protecting energy does not invade Yin portion(陽氣不入於陰). And Huangjaenankyung(黃帝內經) showed cause of insomnia that deficiency of vital energy and blood, imbalanced of spleen and stomach, a fever as a invasion in the outside, lung system's disease. This became a basic cause and process of the sleep disorder in ancient period. 4. Sanghanron(傷寒論) occurred to insomnia as accompanying symptom in progress, remedy of a fever invaded outside, Kumkyeyoriak showed as origination in weakness, fatique, various diseases. Out of that, there is a significance in description of insomnia from some disease like histery or neurosis. 5. Jaebyungwonhuron(諸病源候論), Chunkumbang(千金方), Kukbangseo(局方書.) occured to a fire of heart(心慤) and a deficiency of heart and gall bladder(心膽虛) in defails. Insomnia is caused by agony of seven emotion, delivering of a child, are similar to insomnia is caused by psychologic disorders. Injaesanghanyusu(仁劑傷寒類書) occured to exhausting of Yin and excess of Yang (陰盡陽盛), imbalanced of stomach(胃不和) invasion of coldness(傷寒) are brought a conclusion of assumption of sap(津液耗損) brought about unreturn of yin energy. 6. Manbyunghuechum(萬病回春) in Myung period (明代) made much of portion of phlegm's influence about spiritual function. Kyungakjunsu(景岳全書) valued much of treatment divided according to excess and deficiency. Junginmaekchi(證因脈治) occurred to concept of pyorihesil(表裏虛實), Dongyibokam(東醫寶鑑) synthesised various theories. 7. Hyuljungron(血證論), Byunjungkimun(辨證奇聞), Suksilbirok(石室秘錄) made much of surprisemeni(驚恐) Consideration(思慮), liver's dryness(肝燥) is caused by liver's weakness(肝虛), imbalance of haert -kidney(心腎不交), seven emotion(七情). Especially, ftyujungchijae(類證治載) said that heart, liver, gall-bladder, kidney, surprisment, consideration baought to a conclusion of inbalance of Yang and Yin (陽不交陰). There is a tendency in literature mostly that literature showed separation of insomnia as a chief symptom. 8. These days there are increasing many patient of insomnia. So, it is needed to study about insomnia as a psychologic disease. Saying in conclusion, it is needed that we have to recognize in modern style based on ancient style of cause and process of insomnia. It is regarded to study about insomnia definitely and experimently.

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A Study on Perceptions by College Students of Radiology about the Knowledge, Attitudes and Behaviors of Radiation Exposure Management (방사선과 대학생이 방사선피폭관리에 대한 지식, 태도, 행위에 관한 연구)

  • Yeo, Jindong;Ko, Inho;Kim, Hye-Sook
    • Journal of the Korean Society of Radiology
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    • v.9 no.2
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    • pp.79-99
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    • 2015
  • Participants of this study were students of radiology who were attending colleges or universities located in Daegu and Gyeongbuk. This researcher conducted a questionnaire survey of those students from Feb. 3rd to 21st, 2014. The findings of the study can be summarized as follows. 1. Concerning the knowledge of radiation exposure management, the respondents' scores were highest in two items, or 'Materials based on lead or concrete may shield X-rays' and 'The sexual gland is very sensitive to radiation' and lowest in the item which says' 'Occupational radiation exposure dose should not exceed 20mSv a year in average on a 5-year period basis'. 2. The participants' scores for the attitudes of radiation exposure management were higher in two items, or 'Health examination should be made regularly in relation to radiation exposure' and 'Those who work within the area of irradiation should wear protective clothes' and lowest in the item which says 'Radiation exposure dose should be regularly measured for the calibration of the radiation system'. 3. For the behaviors of radiation exposure management, the surveyed students showed highest scores in two items, or 'When irradiating the patient, the radiator should be behind the protective barrier(plate)' and 'It is needed to receive the education of radiation exposure management regularly' While, their score for a behavior described in the item saying 'Before using the radiation system, it is needed to check whether the machine works normally.

Rethinking Sustainable Development in East Asia : With a Special Reference to Environmental Policies in Korea (동아시아 국가들의 지속가능발전에 대한 재고찰: 한국의 환경정책에 대한 평가를 중심으로)

  • Chung, Hyun-Sik
    • Environmental and Resource Economics Review
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    • v.16 no.3
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    • pp.549-574
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    • 2007
  • This paper was intended to evaluate environmental policies of South Korea and compare its environmental sustainability with other Eastern Asian countries in terms of some sustainability measures. To meet the purpose, the paper is composed of three parts: a brief and critical review of Korea's current environmental policies, comparison of its sustainability with other Eastern Asian countries in terms of well-known environmental sustainability indices, and comparison in terms of a less well-known alternative measure. Korea's environmental policies as stipulated in "Green Vision 21", "Green Korea 2005" were evaluated in light of OECD EPRK 2006. Korea's environmental performance is then compared with other countries based on such environmental sustainability indices as EF, ESI, EPI and EVI. Unfortunately the well-publicized indices to measure sustainable development (SD) seem to fail in measunng SD and in providing comparability, because it does not base on the genuine concept of SD. Therefore, we tried to suggest an alternative measurement in terms of sustainability quantity (SQ), which is presented for South Korea and her major trading partners, such as USA, Japan and China.

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A Survey on the Perception of Agricultural Food Accreditation and Traditional Food Quality Certification (농식품 인증 및 전통식품 품질인증에 관한 인식조사)

  • Huh, Jung-In;Jin, So-Yeon
    • Journal of the Korean Society of Food Culture
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    • v.26 no.3
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    • pp.220-229
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    • 2011
  • This study attempted to understand the perception and the degree of trust that consumers had in the national agricultural food accreditation system, to inquire into and examine the consumers' perception of traditional food quality certification performed for the protection of excellent traditional food, and to propose the right direction for the policies on the traditional food quality certification system and the plans to improve consumers' perception of the system. According to the results of this survey performed in married women, based on the 'the recognition of accreditation system' and 'the recognition of certification marks' of 'the seventh national agricultural food accreditation system' presently being used by the Ministry for Food, Agriculture, Forestry and Fisheries, the household food purchasers showed high recognition for eco-friendly agricultural product accreditation, processed food KS certification, and organically processed food certification in that order. Meanwhile, it was shown that they indicated low recognition for the traditional food-related accreditation systems such as 'traditional food quality certification' and 'food grand master'. It was found that reliability of the certification mark provided by the agricultural food accreditation system gained 3.54 points (on a 5-point scale), and 68.1% of the study subjects referred to the certification marks while purchasing agricultural foods. And most of them answered to the question of 'why they referred to the certification marks' saying that it was done 'to choose safe food'. The most frequent answer to question of 'the means to recognize the traditional food quality certification system' was 'broadcasting, advertising'. 57.3% of the subjects had a previous experience of buying a product certified by the traditional food quality certification system, and 93.2% of all the subjects had the intention to buy a product certified by the traditional food quality certification system later. And most of them answered that 'strengthening government policies' would be the most ideal way to inform the public of the traditional food quality certification system. According to the results of this study, while 'relying on the traditional food quality certification system in general' was relatively high among the consumers, 'intention to buy quality certified products by visiting a distantly located store' was low; thus, from this analysis, it can be seen that there is a need for diversification of places selling these quality certified products and to establish a distribution network for these products.

Optimum N Topdressing for Tillering in Ridge Direct Seeding on Dry Paddy of Rice as an Irrigation Water-Saving Cultural System (벼 휴립건답직파 절수재배에 알맞은 질소 분얼비 시비량)

  • 최원영;김상수;송동석;최선영
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.3 no.2
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    • pp.75-80
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    • 2001
  • This study was conducted to identify the optimum proper nitrogen (N) application rate for tillering in ridge direct seeding on dry paddy of rice culture. During 1998, a series of experiments was carried out at paddy field (Chonbuk series) of the National Honam Agricultural Experiment Station, RDA using Dongjinbyeo. Leaf area index and top dry weight increased with higher N levels, especially in the 100 kg/ha seeding rate compared with the 60 kg/ha seeding rate. N use efficiency increased at increased by 50~75% of the N topdressing rate at tillering. Heading date, ripened grain rate, and 1,000-grain weight of brown rice did not vary among the rate of topdressing for tillering and seeding rates. The highest grain number per unit area was at the level of increased by 75% in N topdressing at tillering stage. Milled rice yield increased 5% at the 60 kg/ha seeding rate and increased 16~17% at the 100 kg/ha seeding rate at increased by 50~75% of topdressing N compared with 48 kg/ha topdressed N of 60 kg/ha seeding rate.

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Research on Sex Education of Young Children's Mothers (유아 어머니의 자녀 성교육 실천정도)

  • Guem, Sun-Hee;Kim, Myung-Hee;Kang, In-Soon
    • Korean Parent-Child Health Journal
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    • v.8 no.1
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    • pp.49-63
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    • 2005
  • Purpose: The present study is a descriptive research on the content of sex education conducted at home by the mothers of young children who are attending five kindergartens located in Busan, Korea. This study aims to provide basic materials for systematic sex education at home and in the school. Method: Based on the literature review and prior researches, the writer made a questionnaire consisting of 30 items regarding necessities, contents and difficulties of sex education. The 307 questionnaires were collected out of 480 which were distributed by the kindergarten teachers. Data was analysed with frequency and percentage using the SPSS Win 10.0 Program. The main subjects of the study were mothers in their thirties, who understood the necessity of sex education. However, they were lack of enough sexual knowledge in accordance with the transforming sexual culture and lack of suitable materials. They did not plan to educate their children according to their developmental stages, but just taught them verbally rather than using common materials for the situation. Result Regarding the origin of life that children often asks, mothers did not give a scientific and correct response to satisfy their curiosity about sex, saying that a baby was created after marrying a loved one. While more mothers than the prior research responded correctly to the queries of the path of delivery, some mothers did not. It may cause some children to suppress the questions, which may result a distorted sexual knowledge. That is because mothers understood that sex education was to deliver sexual knowledge, but not realized that sex education was a human education carried out throughout life. Mothers fell short of sexual knowledge, capability, and confidence, comparing with swift social changes and children's capacity. As a result, it is necessary to inspire sexual awareness into mothers and educate them through training. It is also needed to secure a training program similar to a teacher training program. Conclusion: It is essential to develop and to provide evaluation tools as well as proper materials in accordance with the children's developmental stage, so that organic management system among home, education institute and society must lead sex education Further, it is necessary to provide teaching methods and materials to mothers regularly, so that the school and home may conduct sex education together to cope with difficulties.

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A Study on the Seller's Errors in Internet Shopping Mall Transactions (인터넷쇼핑몰 거래에 있어서 매도인의 착오에 관한 고찰)

  • Yoon, Chang-Sul
    • Journal of Digital Convergence
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    • v.8 no.2
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    • pp.147-160
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    • 2010
  • Internet shopping mall business has taken its place as a major form of e-commerce and is evolving constantly. At the same time, disputes of various kinds are also arising in proportion to the evolution. A typical example is when a consumer purchased a product from an internet shopping mall and the seller wants to cancel or withdraw the sales contract saying that he miswrote the price or other important information when posting the product on the internet. It's about the error on the seller's part. Civil Law Chapter 109, legal principles on errors, appears to assume the case of natural declaration of intention. It was observed that legal principles on errors defined by the Civil Law are also applied in internet shopping malls, where declaration of intention is made electronically. In transactions involving internet shopping malls, where the seller's indication and advertisement constitutes an inducement to offer, the seller may cancel a contract concluded by the consumer's offer and the seller's acceptance if the seller finds errors on his part, and adequacy of the cancellation should be judged depending on specific cases. That is, the judgment of the important ground that comprises prerequisites for cancellation and presence of negligence may depend on how much difference there is between the normal price and the posted price on a specific case. Also, considering the cases where negligence was not perceived on the seller's miswriting of the price, the seller may cancel the transaction in a similar situation.

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Microscopic DVS based Optimization Technique of Multimedia Algorithm (Microscopic DVS 기반의 멀티미디어 알고리즘 최적화 기법)

  • Lee Eun-Seo;Kim Byung-Il;Chang Tae-Gye
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.4 s.304
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    • pp.167-176
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    • 2005
  • This paper proposes a new power minimization technique for the frame-based multimedia signal processing. The derivation of the technique is based on the newly proposed microscopic DVS(Dynamic Voltage Scaling) method, where, the operating frequency and the supply voltage levels are dynamically controlled according to the processing requirement for each frame of multimedia data. The multimedia signal processing algorithms are also redesigned and optimized to maximize the power saving efficiency of the microscopic DVS technology. The characterization of the mean/variance distribution of the processing load in the frame-based multimedia signal processing provides the major basis not only for the optimized application of the microscopic DVS technology but also for the optimization of the multimedia algorithms. The power saying efficiency of the proposed DVS approach is experimentally tested with the algorithms of MPEG-2 video decoder and MPEG-2 AAC audio encoder on the ARM9 RISC processor. The experimental results with the diverse MPEG-2 video and audio files show The average power saving efficiencies of 50$\%$ and 30$\%$, respectively. The results also agree very well with those of the analytic derivations.