• International conference on construction engineering and project management
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• 2005.10a
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• pp.527-532
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• 2005

The construction industries are facing problems of productivity, quality of work, safety, and the completion of projects in time. In construction industry a worker is exposed to hazardous environment, and has to do more physical work, effecting his health and also productivity. The automation and robotics can offer solution to many problems of the industry. In the past the major barrier to construction automation is the lack of electronic components and systems. This is solved now with the development of information technology, and the current obstacle is the high cost of automated systems, shortage of public money for R&D, and problems of acceptance. The robots employed in construction have followed the same concept as those employed in manufacturing. However, construction industry requires a different kind of robot compared to manufacturing Industry. The robots are stationery and product moves along the assembly line in manufacturing sector, but construction robots have to move about the site because buildings are stationary and of large size. The construction robots must function in adverse weather conditions, including variation in humidity, and temperature and increase the overall construction productivity rate. The major objective of the paper is to review the existing applications of building robots and to assess their implementation in building industry. A case study is considered for the implementation of robots for the painting work of the University Building at Saifabad PG College of Science, Hyderabad, India.

• Nuclear Engineering and Technology
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• v.55 no.9
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• pp.3493-3505
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• 2023

Reactor containment buildings serve as the last barrier to prevent radioactive leakage due to accidents and their safety is crucial in overpressurization conditions. Thus, the Regulatory Guide (RG) 1.216 has mentioned the global strain as one of failure criteria in the free-field for cylindrical prestressed concrete containment vessels (PCCV) subject to internal pressure. However, there is a limit that RG 1.216 shows the free-field without the specific locations of failure criteria and also the global strain corresponding to only azimuth 135° has been mentioned in NUREG/CR-6685, regardless of the elevations of the structure. Therefore, in order to reevaluate the failure criteria of the 1:4 scaled PCCV, the high fidelity simulation model based on the experimental test was significantly validated in this study, and it was interesting to find that the experimental and numerical result was very close to each other. In addition, for the consideration of the material uncertainties, the Latin hypercube method was used as a statistical approach. Consequently, it was revealed that the radial displacements of various azimuth area such as 120°, 135°, 150°, 180° and 210° at elevations 4680 mm and 6,200 mm can represent as the global deformation at the free-field, obtained from the statistical approach.

• Nuclear Engineering and Technology
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• v.54 no.12
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• pp.4474-4480
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• 2022

Deep geological disposal using a multibarrier system is a promising solution for treating high-level radioactive (HLRW) waste. The HLRW canister represents the first barrier for the migration of radionuclides into the biosphere, therefore, the corrosion behavior of canister materials is of significance. In this study, the electrochemical behaviors of SS316L, Ti-Gr.2, Alloy 22, and Cu in naturally aerated KAERI underground research tunnel (KURT) groundwater solutions were examined. The corrosion potential, current, and impedance spectra of the test materials were recorded using electrochemical methods. According to polarization and impedance measurements, Cu exhibits relatively higher corrosion rates and a lower corrosion resistance ability than those exhibited by the other materials in the given groundwater condition. In the anodic dissolution tests, SS316L exposed to the groundwater solution exhibited the most uniform corrosion, as indicated by its surface roughness. This phenomenon could be attributed to the extremely low concentration of chloride ions in KURT groundwater.

• Journal of Korean Neurosurgical Society
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• v.66 no.4
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• pp.356-381
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• 2023

Although immunotherapy has been broadly successful in the treatment of hematologic malignancies and a subset of solid tumors, its clinical outcomes for glioblastoma are still inadequate. The results could be due to neuroanatomical structures such as the blood-brain-barrier, antigenic heterogeneity, and the highly immunosuppressive microenvironment of glioblastomas. The antitumor efficacy of endogenously activated effector cells induced by peptide or dendritic cell vaccines in particular has been insufficient to control tumors. Effector cells, such as T cells and natural killer (NK) cells can be expanded rapidly ex vivo and transferred to patients. The identification of neoantigens derived from tumor-specific mutations is expanding the list of tumor-specific antigens for glioblastoma. Moreover, recent advances in gene-editing technologies enable the effector cells to not only have multiple biological functionalities, such as cytokine production, multiple antigen recognition, and increased cell trafficking, but also relieve the immunosuppressive nature of the glioblastoma microenvironment by blocking immune inhibitory molecules, which together improve their cytotoxicity, persistence, and safety. Allogeneic chimeric antigen receptor (CAR) T cells edited to reduce graft-versus-host disease and allorejection, or induced pluripotent stem cell-derived NK cells expressing CARs that use NK-specific signaling domain can be a good candidate for off-the-shelf products of glioblastoma immunotherapy. We here discuss current progress and future directions for T cell and NK cell therapy in glioblastoma.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2021.04a
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• pp.4-4
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• 2021

전 세계는 covid 19의 pandemic 상황이 장기화되면서 화장품 분야의 trend 변화가 일어나고 있다. covid 19의 예방으로 마스크는 생활필수품이 되었고, 행정적으로도 사무공간에서도 마스크를 착용하지 않으면 과태료를 부과하는 상황에 이르렀다. 이로 인하여 장시간 마스크 착용은 필수 불가결한 상황이며, 이로 인하여 얼굴 피부의 장벽기능(barrier function)의 와해로 인하여 피부가 예민해지고 크고 작은 피부의 trouble이 많이 발생하고 있다. 이에 따라 소비자들은 화장품의 선택에 있어 피부 진정과 피부에 자극완화(anti-irritation) 및 안전성(safety)에 대한 것으로 점차적으로 변화하고 있다. Covid 19 이전의 화장품 소재 및 제품 개발의 트렌드는 국내의 기능성화장품 범주에 있는 미백 관련, 주름관련, 자외선 차단관련, 염모관련, 육모 탈모 관련, 여드름관련, 피부장벽관련, 튼살 관련 기능성 소재 및 제품 개발과 화장품 용도외의 고기능성 부여를 위한 코스메슈티컬(cosmeceutical)용 제품의 개발이 중요한 시기였다. 코스메슈티컬(cosmeceutical)은 화장품(cosmetic)과 의약품(pharmaceutical)의 합성어이다. 그러나 최근 Covid 19의 상황에 따라 화장품 업계는 포스트 코로나의 트렌드로 피부 장벽기능 강화, 피부노화 억제, 식물성, 자극완화, 비건, 안전성 확보에 대한 다양한 천연 소재의 연구와 제품을 개발 출시하고 있다. 따라서, 2020년 Covid 19의 상황에 따른 화장품 분야의 천연 신소재 및 화장품 개발 방향에 대하여 자원 식물의 활용성 및 개발 동향에 대하여 논의 하고자한다.

• Journal of Animal Science and Technology
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• v.65 no.6
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• pp.1205-1213
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• 2023

The goals of the present study were to develop a simple method for obtain highly purified pig sperm hyaluronidase (pHyase) and to assess its activity, function, and safety. In mammals, sperm-specific glycophosphatidylinositol (GPI)-anchored Hyase assists sperm penetration through the cumulus mass surrounding the egg and aids in the dispersal of the cumulus-oocyte complex. Recently, Purified bovine sperm hyaluronidase (bHyase) has been shown to enhance therapeutic drug transport by breaking down the hyaluronan barrier to the lymphatic and capillary vessels, thereby facilitating tissue absorption. Commercially available Hyase is typically isolated from bovine or ovine; which have several disadvantages, including the risk of bovine spongiform encephalopathy, low homology with human Hyase, and the requirement for relatively complex isolation procedures. This study successfully isolated highly purified pHyase in only two steps, using ammonium sulfate precipitation and fast protein liquid chromatography. The isolated Hyase had activity equal to that of commercial bHyase, facilitated in vitro fertilization, and effectively dissolved high molecule hyaluronic acid. This simple, effective isolation method could improve the availability of pHyase for research and clinical applications.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2023.11a
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• pp.235-236
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• 2023

The process of construction site supervision plays a crucial role in ensuring safety and quality assurance in construction projects. However, traditional methods of supervision largely depend on human vision and individual experience, posing limitations in quickly detecting and preventing all defects. In particular, the thorough supervision of expansive sites is time-consuming and makes it challenging to identify all defects. This study proposes a new construction supervision system that utilizes vision processing technology and Artificial Intelligence(AI) to automatically detect and analyze defects as a solution to these issues. The system we developed is provided in the form of an application that operates on portable devices, designed to a lower technical barrier so that even non-experts can easily aid construction site supervision. The developed system swiftly and accurately identifies various potential defects at the construction site. As such, the introduction of this system is expected to significantly enhance the speed and accuracy of the construction supervision process.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.11 no.4
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• pp.311-324
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• 2013

To ensure the reliability of computer programs used for the post-closure safety assessment in the Wolsong LILW Center, the results from MASCOT, SAFE-ROCK and GOLDSIM programs are compared with a problem for degradation. Advantages and disadvantages of each computer programs are individually analyzed. Effects on the individual dose are assessed with each computer programs. MASCOT and SAFE-ROCK showed similar results for $^{129}I$ and $^3H$. However, GOLDSIM represented different results for $^{129}I$ and $^3H$. It is analyzed further and compared with the fluxes in each barrier of the disposal system. Througout the benchmarking testing of the computer program, the limitation of computer program can be continuously found out for the mature post-closure safety of Korean radwaste disposal system.

• Journal of the Korean Society of Marine Environment & Safety
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• v.26 no.5
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• pp.483-492
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• 2020

In this study, we compared and analyzed the Revealed Comparative Advantage (RCA) and Trade Specialization Index (TSI) based on ballast water management systems (BWMS) trade data, which are related to the International Maritime Organization (IMO) Ballast Water Management Convention to suggest the current status of Korea's industrial competitiveness and suggest future development directions for the BWMS industry. As international interest in eco-friendly vessels is expanding, the IMO is engaged in dramatic discussions and agreement-making related to marine emissions of pollutants from ships. IMO member states that must implement this convention are striving to develop technology and secure industrial competitiveness as major industries in the eco-friendly shipping sector, with the BWMS industry experiencing a high market entry barrier and the possibility of the leading market entrants gaining leadership. The Republic of Korea accounts for 17 (approximately 38 %) of the 45 BWMS that received final approval as of October 2019. Based on trade data relating to product codes HS842219, HS84212, and HS89, the RCA index and TSI were calculated and compared. The findings revealed that the Republic of Korea has relative inferiority compared to countries such as Germany and Denmark. Despite this, Korea's favorable industrial environment, which includes several IMO-approved BWMS technologies and the possession of domestic certification institutions, is likely to strengthen its competitiveness in the BWMS market.

• Polymer(Korea)
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• v.38 no.2
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• pp.180-187
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• 2014

Nanocomposites including graphene oxide (GO) and conducting polymers (PPy, PANI and PEDOT) were prepared via an in-situ chemical polymerization process, and their characteristic properties depending upon the change of conducting polymer (CP) content were analyzed. A confirmation was made on not only the functional groups formed in GO but also the presence of CP existent in the nanocomposites. The molecular interaction between GO and poly(4-styrene sulfonic acid) (PSSA) or CP in the nanocomposites was proposed. With the increase of PEDOT content in the GOPSS/PEDOT nanocomposite, the estimated value of $I_D/I_G$ regarding the Raman analysis of them was decreased and a major change of their Raman spectra characteristic peaks was observed. In the GO-PSS/PEDOT nanocomposite, PEDOT molecules made an exfoliation of GO-PSSA layers and thus they were intercalated among layers. Such a unique molecular morphology induced the highest electrical conductivity for the GO-PSS/PEDOT nanocomposite among three kinds of nanocomposites prepared in this study. It is also noted that the uniform morphology confirmed in this study helped a thermal stability improvement in the nanocomposite due to the presence of GO or GO-PSSA acting as a thermal barrier.