• 대한물리의학회지
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• 제13권2호
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• pp.137-145
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• 2018

PURPOSE: The purpose of this study was to investigate the effect of action observational physical training with rhythmic auditory stimulation on muscle activity and gait ability in patients with stroke. METHODS: Twenty-six chronic stroke patients participated in this study were assigned into three groups, experimental group 1 (10% faster tempo rhythmic auditory stimulation with action observation training) n=8, experimental group 2 (average tempo rhythmic auditory stimulation with action observation training) n=9, and control group (action observation training) n=9. In this experiment, the corresponding exercise were applied into the subjects of three group for 30 minute a day, 3 time a week during 4 weeks. All participants were measured to muscle activity of lower limb, 10 meter walking test, Figure of 8 walk test, Dynamic gait Index. The collected data were analyzed by using SPSS (version 18.0 for window) and verified that each data was a normal distribution based on Shapiro-Wilk test. Between-group and within-group comparison was analyzed by using One-way ANOVA test, Paired t-test respectively. In all statistical analyses, significance level, ${\alpha}$ was set by .05. RESULTS: The above results revealed that the all experimental group 1 and experimental group 2 and control group were all effective to improve the lower limb muscle activities, gait ability. However more positive effects shown action observational physical training with rhythmic auditory stimulation experimental group. CONCLUSION: This study suggest that action observation physical training with rhythmic auditory stimulation is effective intervention for improvement of muscle activity and walking ability in chronic stroke patients.

• 한국간호교육학회지
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• 제12권1호
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• pp.28-35
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• 2006

Purpose: This study was performed to verify the effect of rhythmic activity program on the elderly particularly their level of instrumental activities of daily living(IADL), depression and sleep. Method: The design of this study is one-group pretest-post test design. Three self-reported questionnaires were used as follows: first, the IADL Scale developed by Lawton and Brody(1969) and revised by Suh(1996) for measuring IADL, second, the Geriatric Depression Scale developed by Sheikh and Yesavage(1986) and revised by Song(1991) for measuring depression, third, Korean Sleep Scale developed by Oh, Song, & Kim(1998) for measuring sleep aspects; fourth, the applied version of Facial Pain Scale developed by Wong & Baker(1988) and revised by Song(2004) for measuring sleep quality. Twenty-seven elderlies carried out 50 minutes of rhythmic activity program for 4 weeks. Before and after the experiment, they were tested for IADL, depression and sleep. Collected data were processed using the SPSS/WIN 12.0 program analyzed by the frequency, percentage, mean and paired t-test. Results: The improvement in IADL of the elderly was not enhanced significantly but depression and sleep disorders significantly decreased. Conclusion: Rhythmic activity program is an effective nursing intervention for the elderly.

• 인간행동과 음악연구
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• 제6권2호
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• pp.25-41
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• 2009

본 연구는 30~50개월 사이의 발달지체 유아 3명을 대상으로 그룹리듬연주활동을 실시하여 모방 능력의 변화를 살펴 본 실험연구로 회당 20~25분씩 주3회, 총 20회기 동안 실시하였다. 프로그램은 총 네 단계로 나누어 사회적 음악 놀이(1-3회기), 유아의 악기 연주를 치료사가 모방하기(4-7회기), 치료사의 악기 연주를 유아가 모방하기(8-18회기), 활동의 복습 및 그룹원이 함께 연주하기(19-20)로 진행되었고 각 회기는 비디오로 녹화돼 연구의 조작적 정의에 따라 연구자 외 두 명의 음악치료사가 검토하였다. 그 결과 첫째, 그룹리듬연주에 따라 유아의 모방능력이 점차 향상되었고, 둘째, 그룹리듬연주의 난이도에 따라 유아들은 1박 모방에서 가장 많은 변화를 보였으며, 셋째, 치료사가 유아의 동작과 연주를 모방했던 3-7회기에 대부분의 유아들은 모방능력에 급진적인 변화가 나타나 타인인지능력의 향상과 더불어 모방 능력이 증진하였음을 알 수 있었다. 이러한 결과로 볼 때 그룹리듬연주활동은 유아의 모방능력을 향상시키며, 차후 복잡한 모방능력의 발달 가능성을 시사하고 있다.

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.258-264
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• 2007

Spatiotemporal changes of brain rhythmic activity at a certain frequency have been usually monitored in real time using scalp potential maps of multi-channel electroencephalography(EEG) or magnetic field maps of magnetoencephalography(MEG). In the present study, we investigate if it is possible to implement a real-time brain activity monitoring system which can monitor spatiotemporal changes of cortical rhythmic activity on a subject's cortical surface, neither on a sensor plane nor on a standard brain model, with a high temporal resolution. In the suggested system, a frequency domain inverse operator is preliminarily constructed, considering the individual subject's anatomical information, noise level, and sensor configurations. Spectral current power at each cortical vertex is then calculated for the Fourier transforms of successive sections of continuous data, when a single frequency or particular frequency band is given. An offline study which perfectly simulated the suggested system demonstrates that cortical rhythmic source changes can be monitored at the cortical level with a maximal delay time of about 200 ms, when 18 channel EEG data are analyzed under Pentium4 3.4GHz environment. Two sets of artifact-free, eye closed, resting EEG data acquired from a dementia patient and a normal male subject were used to show the feasibility of the suggested system. Factors influencing the computational delay are investigated and possible applications of the system are discussed as well.

• Molecules and Cells
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• 제28권5호
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• pp.417-422
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• 2009

Mitogen activated protein kinase (MAPK) are known to get activated during various stress signals and transduce the message from the cell membrane to the nucleus for appropriate cellular reorganization. Though, a certain basal activity of MAPK is often observed in the control plants. Prolonged exposure of rice plants to lowered or elevated temperature exhibited a rhythm in the activation of MAPKs. We analyzed existence of a possible endogenous rhythm in the activity of MAPKs in rice plants. The plants growing at constant temperature entrained in 16/8 h day-night cycle showed diurnal rhythm in activity. When the activation of MAPK was tested under continuous conditions by shifting plants to continuous darkness for a period of 72 h, the periodic rhythm persisted and followed a circadian pattern. Analysis of the transcripts of group A, B and C members of MAPKs under above conditions by quantitative real time PCR revealed that the members of group C exhibit periodic rhythm. Our data indicates that the MAP kinase activity in rice follows rhythmic expression in a circadian manner.

• 한국주거학회논문집
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• 제25권4호
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• pp.83-91
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• 2014

The purpose of this study is to clarify the characteristics between the type of daily routine and spatial configuration of activity areas in classroom and provide alternatives for space planning of activity areas in classroom of child-care centers. This study used the content analysis on daily activity plan and floor plans through field survey. Analysis on floor plans was conducted for 35 classrooms in 9 child-care centers which allowed field survey. The results of this study were as follows; There was no significant difference for classroom size according to the type of daily routine in 3 to 5-year-old classrooms. The average size of classrooms was $61.6m^2$ for care oriented type, $41.4m^2$ for indoor activity oriented type and $48.8m^2$ for group activity oriented type. There was no significant difference in composition of activity areas in classrooms according to the type of daily routine. In case of 0 to 2-year-old classrooms, they were composed of 6 activity areas including gross-motor, role play, block building, language, creative expression, exploration/manipulation. Activity area of the most low frequency was gross-motor area. In case of 3 to 5-year-old classrooms, most classrooms were composed of all the 7 activity areas including art, tone and rhythmic, block building, role play, language, math and science. Most accessible and central areas in 0 to 2-year-old classrooms were gross-motor and role play. Also, most separate areas were exploration/manipulation and block building. Most accessible and central areas in 3 to 5-year-old classroom were art and math. Also, most separate areas were tone and rhythmic and science.

• 자원환경지질
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• 제34권6호
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• pp.627-648
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• 2001

Skaergaard 암체의 중대에는 사장석 우세대와 휘석 우세대가 교대하는 macro-rhythmic layers와 modally-graded, rhythmic lace론 비롯한 최소 두 가지 종류 이상의 layering 발견된다 Macro-rhythmic layers는 LS의 중대에서만 빈번히 발견된다. 두게는 0.3에서 3.3m에 이르고 명확한 상하부 경계를 가지며 노두에서 2km 이상 휭으로 연장된다. 자기 macro-rhythmic layer에서는 내부적인 점이층리 구조를 보이지는 않으나 소규모 modally-graded layer 빈번히 발견된다. Modally-graded, rhythmic layer는 LS의 흔히 발견되나 UBS나 MBS에서는 드물게 관찰된다. 두에는 떼서 50cm에 이르고 노두에서 최대 100m 까지 횡으로 연속된다. 횡적으로 갑자기 혹은 서서히 사라지며 종종 기칠 메우기 구조나 사층리 구조를 수반한다. 명확한 하부 경계와 점이적인 상부 경계와 함께 강한 층간 modal grading이나 size grading이 특징이다. 중대 modally-graded layering중 사장석 우세와 휘석 우세 macro-rhythmic layer두개를 상세하게 조사하였다. 일반적으로 사장석 내의 $K_2$O와 Ba, 휘석, 티탄철석, 그리고 자철석 내의 MgO와 FeO*를 제외한 광물성분변이는 보이지 않는다. 티탄철석과 자철석이 풍부한 layer기저에 산출되는 휘석, 티탄철석, 그리고 자철석의 성분은 MgO가 더 많고 FeO*는 더 적은 경향을 보여준다. 이와 같은 성분변이는 기존의 결정과 Fe가 많은 melt의 상호반응의 결과로 생각되며 Layer 기저에서는 상부보다 적은 re-equilibration를 겪은 것으로 생각된다. 개개 상이나 휘석과 oxide의 비와 reequilibration의 정도 간에는 직접적인 상관관계는 보이지 않는다 휘석 우세 layer거 사장석에 비해 사장석 우세 layer 의 사장석은 UBS의 사장석과 유사하게 상대적으로 적은 $K_2$O와 Eu/Sm를 보이며 이는 사장석 우세 layer는 암체 상부에서 유래한 과외의 사장석에 기인함을 시사한다. 사장석 우세 layer는 대류기에 휘석 우세 layer는 비대류기에 형성되었음을 시사한다. $K_2$O가 적은 사장석 우세 layer의 사장석은 layer내로 통과하는 $K_2$O가 풍부한 liquid와의 reequilibration 에 기인한 것으로 생각된다.

• The Korean Journal of Physiology and Pharmacology
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• 제15권6호
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• pp.415-422
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• 2011

Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ~10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The more recently identified rd10 mice have a later onset and slower rate of photoreceptor degeneration than the rd1 mice, providing more therapeutic potential. In this study, before adapting rd10 mice as a new animal model for our electrical stimulation study, we investigated electrical characteristics of rd10 mice. From the raw waveform of recording using $8{\times}8$ microelectrode array (MEA) from in vitro-whole mount retina, RGC spikes and LFP were isolated by using different filter setting. Fourier transform was performed for detection of frequency of bursting RGC spikes and oscillatory field potential (OFP). In rd1 mice, ~10 Hz rhythmic burst of spontaneous RGC spikes is always phase-locked with the OFP and this phase-locking property is preserved regardless of postnatal ages. However, in rd10 mice, there is a strong phase-locking tendency between the spectral peak of bursting RGC spikes (~5 Hz) and the first peak of OFP (~5 Hz) across different age groups. But this phase-locking property is not robust as in rd1 retina, but maintains for a few seconds. Since rd1 and rd10 retina show phase-locking property at different frequency (~10 Hz vs. ~5 Hz), we expect different response patterns to electrical stimulus between rd1 and rd10 retina. Therefore, to extract optimal stimulation parameters in rd10 retina, first we might define selection criteria for responding rd10 ganglion cells to electrical stimulus.

• 대한임상검사과학회지
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• 제42권2호
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• pp.97-102
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• 2010

The two new female cases of Angelman syndrome (AS) were described, which diagnosed on the basis of clinical features (dysmorphic facial features, severe mental retardation with absent speech, peculiar jerky movements, ataxic gait and paroxysms of inappropriate laughter) and neurophysiological findings. Failure to detect the deletion of the long arm of chromosome 15 or the absence of epileptic seizure were not considered sufficient to exclude a diagnosis of AS. Feeding problems, developmental delay and early signs of ataxia, especially tremor on handling objects and unstable posture when seated, proved effective as the clinical markers for early diagnosis of AS. Most of the authors agreed about the existence of three main EEG patterns in AS which may appear in isolation or in various combinations in the same patient. The most frequently observed pattern in children has prolonged runs of high amplitude rhythmic 2-3 Hz activity predominantly over the frontal region with superimposed interictal epileptiform discharges. High amplitude rhythmic 4-6 Hz activity, prominent in the occipital regions, with spikes, which can be facilitated by eye closure, is often seen in children under the age of 12 years. The EEG findings are characteristic of AS when seen in the appropriate clinical context and can be helpful to identify AS patients at an early age when genetic counselling may be particularly important.

• 한국산학기술학회논문지
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• 제11권9호
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• pp.3353-3357
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• 2010

본 연구는 만성 뇌졸중 환자를 대상으로 시각리듬자극(rhythmic visual stimulation, RVS)을 이용한 보행 운동을 적용하여 보행과 고유수용성감각에 미치는 효과를 알아보고자 하였다. 뇌졸중으로 6개월 이상 장애를 가진 21명이 연구에 참여하였고 실험군 10명과 대조군 11명으로 나누었다. 대조군은 14m의 보행로가 확보된 공간에서 준비운동 5분, 보행운동 20분, 정리운동 5분 씩 주 3회, 4주간 12회를 실시하였고, 실험군은 대조군의 운동프로그램과 같은 조건에서 보행운동시 시각리듬자극(RVS)을 추가적으로 적용하였다. 운동 전 후에 보행과 고유수용성감각을 측정하여 효과를 비교하였다. 통계처리 방법으로 실험 전?후 차이를 검증하기 위하여 Wilcoxon 부호 순위 검정을 실시하였고 대조군과의 차이 검증을 위하여 공분산분석 검정을 실시하였다. 모든 통계적 유의수준은 p<0.05로 하였다. 본 연구의 결과 시각리듬자극(RVS)이 적용된 실험군에서 보행속도와 분속수, Timed up and go test(TUG) 시간이 유의하게 증가하였고(p<.05), 고유수용성감각이 유의하게 증가하였다(p<.05). 결론적으로 시각리듬자극(RVS)을 이용한 보행운동이 만성 뇌졸중 환자의 보행과 고유수용성감각에 효과가 있는 것으로 나타났다. 향후 만성 뇌졸중 환자에게 음악적 요소인 시각리듬자극(RVS)이 정신적 육체적 기능을 상실한 뇌졸중 환자의 재활치료 프로그램에 적용하는 연구가 필요할 것으로 기대된다.