Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Feasibility Study of EEG-based Real-time Brain Activation Monitoring System

뇌파 기반 실시간 뇌활동 모니터링 시스템의 타당성 조사

  • Chae, Hui-Je (Department of Biomedical Engineering, Yonsei University) ;
  • Im, Chang-Hwan (Department of Biomedical Engineering, Yonsei University) ;
  • Lee, Seung-Hwan (Department of Neuropsychiatry, Inje University Ilsan-Paik Hospital)
  • 채희제 (연세대학교 의공학부) ;
  • 임창환 (연세대학교 의공학부) ;
  • 이승환 (인제대 일산백병원 신경정신과)
  • Published : 2007.04.30
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Abstract

Spatiotemporal changes of brain rhythmic activity at a certain frequency have been usually monitored in real time using scalp potential maps of multi-channel electroencephalography(EEG) or magnetic field maps of magnetoencephalography(MEG). In the present study, we investigate if it is possible to implement a real-time brain activity monitoring system which can monitor spatiotemporal changes of cortical rhythmic activity on a subject's cortical surface, neither on a sensor plane nor on a standard brain model, with a high temporal resolution. In the suggested system, a frequency domain inverse operator is preliminarily constructed, considering the individual subject's anatomical information, noise level, and sensor configurations. Spectral current power at each cortical vertex is then calculated for the Fourier transforms of successive sections of continuous data, when a single frequency or particular frequency band is given. An offline study which perfectly simulated the suggested system demonstrates that cortical rhythmic source changes can be monitored at the cortical level with a maximal delay time of about 200 ms, when 18 channel EEG data are analyzed under Pentium4 3.4GHz environment. Two sets of artifact-free, eye closed, resting EEG data acquired from a dementia patient and a normal male subject were used to show the feasibility of the suggested system. Factors influencing the computational delay are investigated and possible applications of the system are discussed as well.

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