• 한국염색가공학회지
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• 제26권2호
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• pp.143-149
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• 2014

The designed dye material, namely 2-(4-(9H-carbazol-9-yl)benzylidene) compound, was synthesized. After the reaction, the solid was filtered and purified by recrystalization with acetone/water. To confirm and analyze its synthesis and structural formation, the single crystal was prepared and its measurement was carried out. A yellow needle crystal of $C_{22}H_{13}N_3$ were made on a Rigaku R-AXIS RAPID diffractometer using graphite monochromated CuK${\alpha}$ radiation. All details were suggested and introduced to support and communicate this study.

• 약학회지
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• 제12권3_4호
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• pp.72-75
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• 1968

It has been believed that "Kup kee" (Chloranthus japonica) is good for boils, or dermatopathia, and enteric fever by the Korean folks. However, there is no scientific report on its chemical ingredients and its antibacterial activities so far. The roots of Chloranthus japonica were dried and pulverized. The pulverized powder was then extracted with methanol. Then an extract was obtained by following Stas Otto's method. finally a crystal fraction was obtained through Column Chromatography. Recrystalization from methanol gave white needle crystals, m.p. $198^{\circ}C.$ Generally this compound has shown strong antibacterial effects on Gram negative bacteria. It exerts most powerful effect on Salmonella typhi. on the other hand it shows weak effect on Inaba cholera.

• 한국식품영양과학회지
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• 제22권5호
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• pp.617-620
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• 1993

한국산 초피나무의 물고기에 대한 독성력을 확인하기 위하여 물질을 용매추출, silica gel column chromatography와 재결정을 통하여 분리 정제하였다. 추출물의 물고기에 대한 독성실험 결과, methanol 추출물에서 가장 강한 독성이 나타났으며, 그 다음으로는 물추출물, 초피의 건조분말 그리고 chloroform추출물 순서로 독성을 보였다. 이 추출물의 구조를 기기분석을 통해 해석한 결과 L-asarinin 임을 확인하였다.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2005년도 춘계학술대회 논문집
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• pp.69-72
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• 2005

The crystal structure of magnesium is hexagonal close-packed (HCP), so its formability is poor at room temperature. But formability is improved in high temperature with increasing of the slip planes. Purpose of this paper is to know about the mechanical properties of magnesium alloy (AZ31B), before warm and hot forming process. The mechanical properties were defined by the tension and compression tests in various temperature and strain-rate. As the temperature is increased, yield${\cdot}$ultimate strength, K-value, work hardening exponent (n) and anisotropy factor (R) are decreased. But strain rate sensitivity (m) is increased. As strain-rate increased, yield${\cdot}$ultimate strength, K-value, and work hardening exponent (n) are increased. Also, microstructures of grains fine away at high strain-rate. These results will be used in simulations and manufacturing factor for warm and hot forming process.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.223.3-224
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• 2003

Chiral discrimination of ibuprofen by $^1$H-NMR using several chiral solvating agents such as (-)-brucine, (-)-cinchonidine, (1R, 2S)-(-)-ephedrine, (S)-(-)-${\alpha}$- methylbenzylamine, (-)-strychnine and L-(-)-tryptophane was investigated. Racemic ibuprofen treated with one equivalent of chiral solvating agent was preferentially crystallized. Chiral purity of each precipitates was measured by chiral HPLC and chemical shift differences(ΔΔ$\delta$) was calculated. Eventhough (S)-(-)-${\alpha}$-methylbenzylamine was most effective for the preferential recrystalization of (S)-(+)-ibuprofen, chemical shift differentiation ability was weak. (omitted)

• 약학회지
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• 제43권2호
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• pp.143-149
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• 1999

The phytochemical studies of the leaves of Caragana chamlagu were carried out as a sieries of the investigation of medicinal resources. The roots of Caragana chamlagu have been used as neuralgia, arthritis and migraine in the folk medicines of Korea. The methanolic extract of the leaves of Caragana chamlagu was suspended with water and then separated with chloroform. Compound I was isolated from precipitates of these water fraction by recrystalization. The aqueous fraction of MeOH extract was performed to column chromatography on Amberlite XAD-4 and Sephadex LH-20, and three compounds, compound II, compound III, and compound IV were isolated. The structures of the four compounds were elucidated by spectroscopic data of $^1H-NMR$, ^{13}C-NMR$, IR, and FAB-MS. Compound I-IV were tilianine ($acacetin-7-O-{\beta}-D-glycopyranoside$), rutin($quercetin-3-O-{\alpha}-L-rhamnopyranosy(1{\rightarrow}6)-{\beta}-D-glu-copyranoside$), $kaempferol-3-O-{\alpha}-L-rhamnopyranosyl(1{\rightarrow}6)-{\beta}-D-galactopyranoside$, and apigetrin, ($apigenin-7-O-{\beta}-D-glycopyranoside$), respectively.

• Natural Product Sciences
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• 제17권3호
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• pp.230-233
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• 2011

To evaluate the potential of naturally occurring aldose reductase (AR) inhibitors from food material, MeOH extract and stepwise polarity fractions from tartary buckwheat and two common Korean buckwheat cultivars, yangjul-maemil and daesan-maemil, were tested on AR inhibition in rat lens in vitro. The EtOAc fraction from tartary buckwheat exhibited good AR inhibitory activity ($IC_{50}$ value, $8.19\;{\mu}g$/ml). A portion of the EtOAc fraction from tartary buckwheat led to the isolation of rutin by MeOH recrystalization. Rutin exhibited good AR inhibitory activity ($IC_{50}$ value, $9.28\;{\mu}M$). These results suggest that tartary buckwheat could be a useful food material in the development of a novel AR inhibitory agent against diabetic complications.

• 한국약용작물학회지
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• 제9권4호
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• pp.269-274
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• 2001

쑥갓(Chrysanthemum coronarium L.) 꽃으로부터 암 예방활성 성분을 가진 2종의 화합물을 분리하여 다양한 spectral data를 종합한 결과, sesquiterpene lactone계인 eudesmanolide의 일종으로 밝혀졌으며 , compound 1과 2는 각각 douglanine과 reynosin인 것으로 동정되었다. 이 화합물들은 쓱갓에서는 처음으로 분리 보고되는 화합물이며, 세포독성을 측정한 결과, 두 화합물 모두 3종의 인체암 세포주에 대하여 비교적 강한 활성을 나타내었다.

• 대한화장품학회지
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• 제24권3호
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• pp.45-50
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• 1998

13 develop an active agent for skin whitening, we examined the inhibitory effects of 285 plant extracts on tyrosinase activity and found some plant extracts have an ability to inhibit tyrosinase activity. Of these plant extracts, ramulus mori extracts showed the highest inhibiting activity on enzyme activity. From these results, we selected ramulus mori as a new active agent for skin whitening. $IC_{50}$/ of this extracts on tyrosinase activity is 12.48$\mu\textrm{g}$/m1. Also, ramulus mori extracts showed inhibitory activity on melanin synthesis in B-16 melanoma cells. We isolated active compound from ramulus mori extracts using various column chromatography and recrystalization and identified its chemical structure using Mass spectroscopy, IR and NMR analysis. So, it is identified as Mulberrin, a maior compound of ramutus mori and turned out that it has potent ability on tyrosinase inhibition. $IC_{50}$/ of this compound for tyrosinase activity is 0.5$\mu\textrm{g}$/ml. Also, this compound showed potent inhibitory activity on melanin synthesis in B-16 melanoma cells. This extracts was turned out to be safe in many safety tests.

• The International Journal of Costume Culture
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• 제4권1호
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• pp.18-24
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• 2001

Agricultural drainage salt generated during irrigation of crops in San Joaquin Valley, California, exceeds 600,000 tons annually and cumulates in the field in a rapid rate. As a result, the waste is taking out more farmlands for salt storage and disposal, imposing serious concerns to environment and local agricultural industry. In searching for a potential solution to reduce or eliminate the waste, this research explored feasibility of producing a value -added product, sodium sulfate, from the waste and utilizing the product in textile dyeing. The results indicated that sodium sulfate could be produced from the salt and could be purified by a recrystalization method in a temperature range within the highest and lowest daily temperatures in summer in the alley. The recovered sodium sulfate samples, with purities ranging from 67% to 99.91, were compared with commercially available sodium sulfate in direct dyeing of cotton fabrics. The salt samples recovered from Mendata, California (〉98.8% sodium sulfate) cause little color difference in the dyeing with selected direct dyes, and the purified salt (Ⅲ) (99.91% sodium sulfate) is more applicable for direct dyeing of cotton fabrics if it has no other toxic effects. The recovered sodium sulfate from certain areas in the valley could not be employed in direct dyeing due to the high level of impurities in it.