• 제목/요약/키워드: Prospective Studies

검색결과 851건 처리시간 0.034초

The link between Helicobacter pylori infection and gallbladder and biliary tract diseases: A review

  • Klay Puay Khim Lim;Aaron Jia Loong Lee;Xiuting Jiang;Thomas Zheng Jie Teng;Vishal G. Shelat
    • 한국간담췌외과학회지
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    • 제27권3호
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    • pp.241-250
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    • 2023
  • Helicobacter pylori is a gram-negative pathogen commonly associated with peptic ulcer disease and gastric cancer. H. pylori infection has also been reported in cholelithiasis, cholecystitis, gallbladder polyps, and biliary tract cancers. However, the association between H. pylori and gallbladder and biliary tract pathologies remains unclear due to the paucity of literature. In response to the current literature gap, we aim to review and provide an updated summary of the association between H. pylori with gallbladder and biliary tract diseases and its impact on their clinical management. Relevant peer-reviewed studies were retrieved from Medline, PubMed, Embase, and Cochrane databases. We found that H. pylori infection was associated with cholelithiasis, chronic cholecystitis, biliary tract cancer, primary sclerosing cholangitis, and primary biliary cholangitis but not with gallbladder polyps. While causal links have been reported, prospective longitudinal studies are required to conclude the association between H. pylori and gallbladder pathologies. Clinicians should be aware of the implications that H. pylori infection has on the management of these diseases.

Preparations for the Assessment of COVID-19 Infection and Long-Term Cardiovascular Risk

  • Jaehun Jung
    • Korean Circulation Journal
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    • 제52권11호
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    • pp.808-813
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    • 2022
  • Studies showing that coronavirus disease 2019 (COVID-19) is associated with an increased risk of cardiovascular disease continue to be published. However, studies on how long the overall cardiovascular risk increases after COVID-19 and the magnitude of its long-term effects have only been confirmed recently. This is partly because the distinction between cardiovascular risk as an acute complication of COVID-19 or post-acute cardiovascular manifestations is ambiguous. Long-COVID has arisen as an important topic in the second half of the pandemic. This term indicates that symptoms persist for more than two 2 months; following three months of SARS-CoV-2 infection and cannot be explained by other medical conditions. Despite the agreement of these international organizations and experts, it is difficult to define whether there is sufficient medical evidence to prove the existence of long-COVID. However, the Korean government and Korea Disease Control and Prevention Agency (KDCA) are preparing a new platform to assess the long-term impact of COVID-19. Using this data, a prospective cohort of 10,000 confirmed COVID-19 cases will be established. This cohort will be linked with claims data from the National Health Insurance Services (NHIS) and it is expected that increased real-world evidence of long-COVID will be accumulated.

수격자점을 꼭지점으로 갖는 정육면체의 개수 -지오보드의 활용- (Cubes with lattics-point vertices)

  • 이만근
    • 대한수학교육학회지:수학교육학연구
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    • 제8권1호
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    • pp.137-144
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    • 1998
  • A common geoboard puzzel serves as the point of departure for an investigation that lends itself to whole-group discussion with a class of prospective secondary school teachers. Students are provided with opportunities to devise and carry out problem-solving strategies (called 'heuristics' by Polya); exploit inerrelationships among geometry, arithmetic and algebra; formulate generalizations and conjectures; plan and execute an computational project; construct mathematical arguments to establish theorems; and find counter-examples to dispose of a false conjecture. In recent tears, Eugene F. Krause wrote two papers having the same title except for the numeral In that papers he arrives at an theorem about the sizes of squares with lattice point vertices in the coordinate plane, In this paper we follow a different path genearlization to coordinate 3-space

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Applications on p-values of Chi-Square Distribution

  • Hong, Chong Sun;Hong, Sung Sick
    • Communications for Statistical Applications and Methods
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    • 제9권3호
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    • pp.877-887
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    • 2002
  • In this paper, behaviors and properties of p-values for goodness-of-fit test are investigated. With some findings on the p-values, we consider some applications to determine sample size of a survey research using the regression equation based on a pilot study data. Regression equations are obtained by the well-known least squared method, and we find that regression lines could be formulated with only two data points, alternatively. For further studies, this works might be extended to t distributions for testing hypotheses about population mean in order to determine sample size of a prospective study. Also similar arguments could be explored for F test statistics.

AHP의 절대적 측정을 이용한 비대면 개인대출심사모형의 개발 (A Non Face-to-Face Private Loan Screening Model Employing the Ratings Approach of AHP : Development and Validation)

  • 민재형;김우섭
    • 경영과학
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    • 제33권3호
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    • pp.65-87
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    • 2016
  • Being the FinTech technologies rapidly developed, the non face-to-face private loan market is also growing dramatically. While the real-world interests in this market are keen, the empirical studies on the issue are few compared to its prospective impact on credit loan market. This paper suggests a credit scoring model for the non face-to-face private loan employing the ratings approach (the absolute measurement method) of AHP. Analyzing a sample of data consisting of 460,000 transaction records over an 8-year period in the United States, we develop a scoring model for the non face-to-face private loan screening, and validate the model for the practical usage. Conducting sensitivity analysis, we suggest customized cut-off points for the loan execution to suit each individual loan institution's need.

흉부식도암의 외과적 치료 (Surgical Treatment of Thoracic Esophageal Cancer)

  • 박창권
    • 대한기관식도과학회지
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    • 제9권1호
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    • pp.39-46
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    • 2003
  • Surgery remains the standard treatment for resectable thoracic esophageal cancer but that is justified only when acceptably low morbidity and mortality rates can be achieved even for advanced disease. The appropriate extent of resection to achieve the best outcome is the most controversial aspect of treating esopahgeal cancer and the optimal excent of lymphadenectomy also remains controversial. Until data from prospective randomized trials showing a clear benefit using a particular approach are available, surgeons should perform their better judgement in individualizing and selecting the most appropriate surgical approach to provide the best chance of cure or lasting palliation for this disease that challanges both patient and surgeon. Further studies are necessary to examine the utility and efficacy of each approach in treating thoracic esophageal cancer either alone or in combination with other modalities.

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Qi-therapy, chaotic characteristics of peripheral blood pressure and biochemical variables

  • Lee, Myeong-Soo;Rim, Young-Hoon
    • Advances in Traditional Medicine
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    • 제4권3호
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    • pp.215-218
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    • 2004
  • We investigated the effect of Qi therapy (QT) on peripheral blood pressure (PBP), glucose, lactate dehydrogenase (LDH) and cortisol concentrations. Fourteen college students participated in receiving QT and placebo treatment. There were significant differences in embedding dimension of PBP. Plasma cortisol concentrations during QT were significantly lower than during control sessions (P

Update of Sepsis: Recent Evidences about Early Goal Directed Therapy

  • Cho, Woo Hyun
    • Tuberculosis and Respiratory Diseases
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    • 제78권3호
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    • pp.156-160
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    • 2015
  • Severe sepsis and septic shock is a life-threatening disease. It is combined with multi-organ failure. In the past decade, early goal directed therapy has been proposed as an effective treatment strategy for better outcome. Recent epidemiologic studies showed that the outcome of sepsis has been improved with the introduction of early goal directed therapy. However, it is unclear which elements of early goal directed therapy contributed to the better outcome. Recent prospective and randomized trials suggested that some elements of early goal directed therapy did not have any effect on the outcome benefit. In this paper, recent articles about early goal directed therapy will be reviewed and the effectiveness of individual elements of early goal directed therapy will be discussed.

신생아의 급성신손상 (Acute Kidney Injury in the Newborn: Etiology, Pathophysiology and Diagnosis)

  • 김소영
    • Neonatal Medicine
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    • 제17권2호
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    • pp.161-167
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    • 2010
  • Acute kidney injury (AKI), formerly referred to as acute renal failure (ARF) is defined as the sudden impairment of kidney function (estimated from the glomerular filtration rate [GFR]) that results in the lack of excretion of waste products. More than 30 definitions of AKI exist in the literature, most of which are based on serum creatinine. Lack of a uniform and multidimensional AKI definition has led to failure to recognize significant renal injury, delays in treatment, and inability to generalize single-study results. The RIFLE criteria were developed to standardize the diagnosis of ARF and in the process the term AKI has been proposed to encompass the entire spectrum of the syndrome from minor changes in renal function to requirement for renal replacement therapy. Large prospective studies are needed to test definitions and to better understand risk factors, incidence, independent outcomes, and mechanisms that lead to poor short- and long-term outcomes. Early biomarkers of AKI need to be explored in critically ill neonates.

웨어러블 디바이스 기반의 게임콘텐츠 전망 연구 (A Prospective Study of Game Content based on Wearable Device)

  • 백재용;장효진;김영재
    • 디지털산업정보학회논문지
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    • 제11권1호
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    • pp.145-155
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    • 2015
  • The game industry has changed along with the advancement of device technology. The wearable, a recently appeared device will create new demand in this saturated age of the smart devices. The game industry's content targeted towards the wearable devices will play an important role as main driving source. For this reason, this research studies the development aspect and the current technical capabilities of games' platforms and contents by analyzing the contrast between the results of features and current situations of the wearable market. Consequently, we define the prospects of game content for wearable device. We also expect that the new style of the game content, combined with cloud game, augmented reality game and virtual reality game will appear in the next generation platforms gearing towards the wearable devices.