• 한국노년학
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• v.32 no.4
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• pp.993-1011
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• 2012

The purpose of this study is to investigate the factors associated with the incidence and the transition of disability among Korean older adults. Samples consist of 1,454(42.7%) men and 2,032(58.3%) women aged 65 and over who participated in the 1st and 2nd wave of the Korea Longitudinal Study of Aging: KLOSA. To estimate the level of disability, ADL and IADL disability indexes are used. As the results, major risk factors for ADL/IADL disability incidence include injury, vision problem, cognitive function, depression, health behavior, socioeconomic characteristics and age. Among the normal older adults, the odds ratio of having dementia symptoms at 2nd wave(2008) are 2.0 times greater for the older adults who have less cognitive function than those who don't have at 1st wave(2006). Among the older adults with chronic diseases, the odds ratio of having disability at 2nd wave are 1.8 times greater for the older persons who have depression than those who don't have at 1st wave. Secondly, concerning the predictors affecting the disability transition among the disabled older adults at 1st wave, the likelihood of remaining at the same level or deteriorating the level of IADL disability, as compared with improving the level, is associated with having less instrumental support or being older. These results indicate that it is necessary to prefer multilevel intervention in order not only to prevent the incidence of disability, but also to prolong the deterioration of disability in the older adults.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.1
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• pp.119-123
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• 2019

Obstructive sleep apnea (OSA) is a sleep disorder with no breathing symptoms due to repetitive upper airway resistance. OSA is a disease that can have significant effects on the cerebral cardiovascular system. Active treatment is needed to prevent these complications. The use of continuous positive airway pressure (CPAP), the standard therapy of OSA, has comparative therapeutic effects. On the other hand, there is no comparison report of the polysomnography (PSG) results before and after CPAP therapy without using a mask. This paper reports a patient who was diagnosed as OSA and used CPAP every night for more than 2 years. The patient showed a decrease in the apnea-hypopnea index from 64.7/h to 12.9/h. In addition, other sleep-related indicators improved significantly. The daily use of CPAP as a treatment for OSA for more than 2 years may improve the PSG results. Constant follow up of PSG will be needed to adjust the appropriate CPAP pressure to patients because there might be a change in the Apnea-Hypopnea Index and other sleep-related indicators for constant CPAP users for at least 2 years.

• Journal of the Korea Convergence Society
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• v.10 no.7
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• pp.317-323
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• 2019

Amid the recent growing social demand for wellness culture and healing tourism, I, through a literature survey and case study, reviewed the conditions of healing tourism in Gangwon-do as a destination of healing tourism, and examined the development project of Gangwon-do type healing tourism and commercialization of the wellness perspective. According to the survey, it was found that the Yeongdong area in Gangwon Province had excellent healing-based conditions in virtue of abundant natural resources, but it was found that it was necessary for local governments to cooperate in order to prevent overlapping investments and create synergy effects by connecting with one another as development contents or business items of healing tourism projects overlap or remain in the planning stage. In the case of Goseong-gun, which was reviewed as the main site, it has high potential as a silver-healing tour and if the County seeks a wellness merchandising strategy for each healing tourism target based on a therapy program linked with local specialized resources, and effectively links and specializes regional strengths in Gangwon-do's Yeongdong region, it is expected to become a regional success story of operating the development of the local tourism for silver and health-oriented tourists.

• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.7
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• pp.858-868
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• 2017

Korea's shipbuilding industry has led the world in the technical area over the last century. Despite this commendable performance, around 2,000 workers experience accidents almost every year with 40 being killed. This raises a question of whether the safety level of our shipbuilding industry, in particular the safety of workers, is actually at the world-class level. Accordingly, this research has analyzed several types of safety training currently provided in the field through investigating statistical data of serious accidents occurring from 2006 to 2015 in the domestic shipbuilding industry, analyzing its occurrence and causes, and conducting a survey targeting employees in the shipbuilding industry. Based on this, it has investigated problems of safety training in the shipbuilding industry and suggested improvements. First, it is essential to create a standard system for safety training in the shipbuilding industry to address problems of different kinds and levels of safety training provided by each shipyard and low quality of training, and operate more organized and systemized training. Second, safety training curriculum specializing in the shipbuilding industry should continue to be developed and standardized based on a standard system for safe training to prevent serious accidents and improve safety awareness of workers. Lastly, both employers and employees should actively provide and participate in safety training to secure safety of workers through preventing serious accidents and ultimately create safety-first culture in workplace.

• Korean Journal of Microbiology
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• v.55 no.3
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• pp.226-233
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• 2019

Ochratoxin A (OTA) that is one of mycotoxins produced mainly by Aspergillus spp. is a common contaminant of stored grains and poses health hazards to human and livestock. The aim of this study is to explore the ability of isolated bacteria Bacillus subtilis AF13 and Streptomyces shenzhenensis YR226 to inhibit growth and OTA production of 3 ochratoxigenic Aspergillus strains. The antifungal activity against mycelial growth and sporulation of Aspergillus strains was examined by coculture with AF13 and YR226 on potato dextrose agar plate. AF13 and YR226 reduced 77.58 and 78.48% of fungal colony radius, respectively, and both strains inhibited fungal sporulation up to 99% in 10 days of incubation. YR226 also reduced more than 91% of spore germination of 3 fungal strains. When Aspergillus strains were cocultured with AF13 or YR226 in yeast extract sucrose medium, mycelial growth and OTA production decreased in all three fungal strains. In particular, AF13 completely inhibited the mycelial growth of A. alutaceus and inhibited its OTA production by 99%, and YR226 also reduced mycelial growth and toxin production up to 99%, respectively. Antimicrobial substances produced by AF13 and YR226 included siderophore, chitinase, protease, ${\beta}$-1,3-glucanase and biosurfactant. These results suggest that AF13 and YR226 can be used in a biological method to prevent valuable crops against mycotoxigenic fungi, and therefore decrease economic damage in agriculture and feed industry.

• Journal of Industrial Convergence
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• v.16 no.4
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• pp.1-8
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• 2018

This study aimed to provide basic data on health promotion programs to prevent cardiocerebrovascular Disease by identifying knowledge, attitude and self-efficacy. Data were collected from 198 middle-aged adults in S-city. The data analysis was analyzed with technical statistics and t-test, ANOVA, Pearson's correlation coefficient. There were significant differences in knowledge depending on the age, education level, monthly income and there were significant differences in attitude depending on the education level and monthly income. There were also significant differences in self-efficacy between gender. The correlation analysis also showed a significant correlation between knowledge of cardiovascular disease and attitudes toward prevention(t=.45, p<.001). In other words, the higher your knowledge of cardiovascular disease, the more positive you are about preventing it. Therefore, it is necessary to develop education and mediation programs that can form a positive attitude toward preventing cardiocerebrovascular disease and to develop programs that enhance the self-efficacy of middle-aged men.

• Journal of the Korea Institute of Building Construction
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• v.19 no.2
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• pp.185-192
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• 2019

Construction has been well known as the industry in which accidents occur more often than other industries. The efforts to eliminate the accidents at construction sites need to be continuously conducted because they tend to cause the social problems such as massive loss of life and property. According to the Korea Occupational Safety and Health Agency (KOSHA), 26,570 (29.3 percent) out of 90,656 workers in total industrial accidents have been occurred in the construction industry in 2016. Particularly, the falling victims are the largest number, which is about 8,699. This number is increasing due to the increase of the large scale, high-rise, and complex construction structures and the various construction methods. In reality, there is a lack of analysis on the risk factors of safety accidents and preventive measures. Therefore, in this study, we have selected risk factors by analyzing the accident cases at construction sites. Based on the results, we conducted a safety practitioner-focused survey and had an interview with safety managers. In analyzing the cases, we have categorized them into three groups such as upper, middle, and lower and compared their statistical results. This study are expected to provide safety management guidelines with workers and safety managers to prevent previously fall accidents at construction site.

• Journal of the Korea Convergence Society
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• v.12 no.3
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• pp.389-399
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• 2021

This study is the quasi-experimental research of nonequivalent groups and is designed to investigate the effects of an aquatic exercise program with diabetes self management education on the self care efficacy, self care behaviors in diabetic patients in community. The subjects of this study were 26 patients in the experimental group who participated in the aquatic exercise program and 25 patients in the control group who did not paricipated in. And they were registered at the W Health Clinic in D city. The aquatic exercise program was conducted twice a week for 80 minutes, and consisted of a 30 minutes diabetes self management education and a 50 minutes aquatic exercise. After this program, there were significant differences in FBS(p=.047), HbA1c(p<.001), diabetes self efficacy(p<.001), and self care behaviors(p<.001). In order to reduce the prevalence of diabetes and prevent complications in the community, it is believed that the constant operation of aquatic exercise programs including self management education is necessary.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.413-419
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• 2021

The purpose of this study was to investigate the ability to treat and prevent infection by multiple Gram-negative bacterial pathogens as a last choice option in the treatment of serious infections in clinical settings. The global spread of extended-spectrum 𝛽-lactamases (ESBLs) and/or carbapenemases in microorganisms are of enormous concern to health services because they are often associated with multi-drug resistance which significantly restricts the antibiotic treatment options. In this study, the antimicrobial resistance profiles of bacteria isolated from South Korean market-derived meat samples were determined by the disc diffusion method. PCR was used to detect the presence of antibiotic resistance genes and ESBL producing genes. In total, we tested 181 isolated colonies from 36 market-derived meat samples. Single PCR and DNA sequencing results revealed that genes blaVIM, blaBIC, blaKPC, and blaSIM were present in the bacteria isolated from retail meat. The bacteria in the meat were separately sequenced and based on alignment, four different bacteria were identified. These findings suggest that bacteria found in retail meats are a reservoir for the spreading of ESBL blaVIM, blaBIC, blaKPC, and blaSIM resistance genes and bacteria strains.

• Natural Product Sciences
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• v.27 no.2
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• pp.86-98
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• 2021

This study was designed to characterize the effect of ginsenoside-Rg2 (Rg2), one of panaxatriol saponins isolated from Korean ginseng root, on the release of catecholamines (CA) in the perfused model of the rat adrenal medulla, and also to establish its mechanism of action. Rg2 (3~30 µM), administered into an adrenal vein for 90 min, depressed acetylcholine (ACh)-induced CA secretion in a dose- and time-dependent manner. Rg2 also time-dependently inhibited the CA secretion induced by 3-(m-chloro-phenyl-carbamoyl-oxy)-2-butynyltrimethyl ammonium chloride (McN-A-343), 1.1-dimethyl-4-phenyl piperazinium iodide (DMPP), and angiotensin II (Ang II). Also, during perfusion of Rg2, the CA secretion induced by high K⁺, veratridine, cyclopiazonic acid, methyl-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoro-methyl-phenyl)-pyridine-5-carboxylate (Bay-K-8644) depressed, respectively. In the simultaneous presence of Rg2 and N^ω-nitro-L-arginine methyl ester hydrochloride ʟ-NAME), the CA secretion induced by ACh, Ang II, Bay-K-8644 and veratridine was restored nearly to the extent of their corresponding control level, respectively, compared to those of inhibitory effects of Rg2-treatment alone. Virtually, NO release in adrenal medulla following perfusion of Rg2 was significantly enhanced in comparison to the corresponding spontaneous release. Also, in the coexistence of Rg2 and fimasartan, ACh-induced CA secretion was markedly diminished compared to the inhibitory effect of fimasartan-treated alone. Collectively, these results demonstrated that Rg2 suppressed the CA secretion induced by activation of cholinergic as well as angiotensinergic receptors from the perfused model of the rat adrenal gland. This Rg2-induced inhibitory effect seems to be exerted by reducing both influx of Na⁺ and Ca²⁺ through their ionic channels into the adrenomedullary cells as well as by suppressing Ca²⁺ release from the cytoplasmic calcium store, at least through the elevated NO release by activation of NO synthase, which is associated to the blockade of neuronal cholinergic and AT₁-receptors. Based on these results, the ingestion of Rg2 may be helpful to alleviate or prevent the cardiovascular diseases, via reduction of CA release in adrenal medulla and consequent decreased CA level in circulation.