• Journal of radiological science and technology
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• v.31 no.1
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• pp.33-39
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• 2008

Abdominal obesity, especially, visceral obesity is thought to be a risk factor of type 2 diabetes and cardiovascular disease such as hypertension, hyperlipidemia, coronary artery disease. Based on previous studies visceral fat accumulation is highly related to these diseases compared to subcutaneous fat accumulation. The purpose of this study was to see the relation between abdominal obesity and lipid profiles in adult women. The included subjects were 25 adult women(BMI > $23\;kg/m^2$), who visited the obesity clinic in a general hospital from April 2006 to September 2007. Blood pressure, fasting glucose and lipid profiles were measured. The abdominal fat distribution had been assessed by CT scan at the level of L4-L5. From bivariate analyses, the visceral fat accumulation showed negative correlations with TC and TC/HDL. The BMI, total abdominal fat and Visceral fat/Subcutaneous fat ratio showed significant correlations with visceral fat accumulation. From linear regression analyses of all the study subjects, TC, TG and HDL were found to be determinants of the visceral fat accumulation($R^2\;=\;0.474$).

• Korean Journal of Community Nutrition
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• v.2 no.3
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• pp.319-326
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• 1997

This study was to investigate the level of serum lipids and obesity in housewives in Mooan, and relationships between them. The average age, height and weight were 51.1 years, 154.3cm and 58.3kg respectively. The level of obesity of subjects was higher than that of housewives in other areas investigated in other studies. BMI and RBW underestimated in the obese compared to BIA. The amounts of lean body mass and total body water of subjects above 60 years old were smaller than those of forties and their BMI and RBW were lower than those of forties. However, their body fat percentage was nearly same as that of forties. Serum HDL-cholesterol(HDL-C) of subjects was lower than 55mg/㎗, the lower limit of normal range. Triglyceride of subjects above 60years old was higher than the 95th percentile of those of the same age with reference to Mayo clinic. The serum total cholesterol(TC) showed positive correlation with LDL-cholesterol(LDL-C) and TC/HDL-C(p<0.001). LDL-C showed positive correlation with TC(p<0.001), but negative correlation with HDL-C(p<0.05). HDL-C showed negative correlation with triglyceride(p<0.05). TC/HDL-C showed a positive correlation with triglyceride(p<0.05). HDL-C was the serum lipid which showed the highest correlation with obesity and body composition. It showed a negative correlation with the percentage of body fat(p<0.001), total body fat(p<0.001), BMI(p< 0.05) and RBW(p<0.05). TC/HDL-C showed positive correlation with the percentage of body fat(p<0.01) and total body fat(p<0.05). As the result of above, it is needed to make more researches to find out the proper method to estimate the obesity of subjects and educate subjects in Mooan about nutritional information for obesity.

• Journal of Sasang Constitutional Medicine
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• v.16 no.1
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• pp.100-111
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• 2004

Objectives To study on the relation between Sasang constitution and obesity and that of obese patient's clinical symptom. Methods The subjects were 129 female patients to visit to diet. The subjects were 129 female patients to diet who answered questionnaire QSCC II and were diagnosed by the Sasang constitution from May to December in 2001 at Nara oriental medical clinic. Results 1. Of obese patients 79.1% were Taeumin, 11.6% Soeumin, and 9.3% Soyangin. 2. A relation of a grade of obesity and Sasang constitution. 2-1) 45.8% of the obese patients were high level obesity who had over 35% of body fat. Out of these people, 91.5% were Taeumin. 2-2) 40.3% of the obese patients weight hip ratio was between 0.84 to 0.89 and 84.6% of these people were proved to be Taeumin. 2-3) 39.2% of the people who had a minimum weight hip ratio of 0.90 were significantly Taeumin, 6.7% Soeumin and 16.6% Soyangin. 2-4) 65.7% of Taeumin were obese patients. 3. Obesity treatment with constitution. 3-1) 59.8% of Taeumin were Pyo-zng patients. 3-2) As treatment periods tended to increase, Taeumin and Soeumin patients showed a large decling of body fat, whereas Soeumin patients showed the opposite reaction. 3-3) The weight hip ratio was led by Taeumin with 0.03 and then came Soeumin and Soyangin with a 0.02 ratio. As treatment was taken into process longer Taeumin patients showed a great progress in decreasing their weight hip ratios. 4. Costitutional related symptom with Obesity. 4-1) Taeumin was followed by Soyangin and then Soeumin in family history. 4-2) Soeumin was followed by Taeumin, then Soyangin when complain of physical fatigue was taken into consideration. 4-3) The ordinary exercise was led by Soyangin, Taeumin then Soeumin. 4-4) People who receive stress turned out to be 72.9% much higher than the people who don't. 4-5) Overeating due to stress was found in 83.3% of Soyangin.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.17 no.2
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• pp.112-121
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• 2013

Objectives This study analyze the correlation between iris markings and the obesity level shown in body composition indices. And It quantitatively evaluates iris markings according to the level of obesity to improve a clinical application plan for the iris analysis. Methods This study analyzed the iris and body composition through the quantization of iris markings for 28 female patients. It calculated descriptive statistics by using SPSS 13.0 and investigated correlation coefficients of non-parametric Spearman in order to analyze the relation between iris markings and body composition indices. Results Considering the correlation between iris markings and body composition indices, an area of the pupil had a significant positive correlation with height and with fat-free amount such as body water, protein, and minerals. BMI showed significant positive correlations with the length of the autonomic nerve wreath and the ratio of the autonomic nerve wreath, and the area of the autonomic nerve wreath. Moreover, the number of lacunas in the pancrea area had a significant positive correlation with weight and BMI. Conclusions This study objectifies the quantification of iris markings to identify the correlation between iris markings and the level of obesity. The study results will be used as a basic data to make standards for the diagnosis of obesity, the treatment of related diseases, and the diagnosis of iris markings for prevention.

• Journal of Korean Medicine for Obesity Research
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• v.8 no.1
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• pp.53-61
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• 2008

Objectives We have investigated a questionnaire on syndrome differentiation pertaining to obesity. To calculate data from this questionnaire, we can simply sum up the degree of symptoms. However, this does not reflect the difference in contribution of syndrome differentiation. In order to improve the level of precision of this questionnaire, we gather the weight of each symptom from experts and apply them to overweight persons. Method Nine Experts from The Society of Korean Medicine for Obesity Research nominated weights for the symptoms. We created a program based on weight survey results and applied to 1487 overweight persons and 26 oriental medical doctors. The concordance rate between the result obtained from the oriental medical doctors and that obtained using three methods was analyzed. Results 1. The reliability of this questionnaire is very high (Cronbach' ${\alpha}$=0.963). 2. The concordance level between diagnosis by oriental medical doctors and the result of general calculation is 0.347, between diagnosis by oriental medical doctors and the result of weighted calculation by syndrome differentiation is 0.362, between diagnosis by oriental medical doctors and the result of weighted calculation by symptoms is 0.1. Conclusions Weighted calculation by syndrome differentiation is relative more appropriate among three methods studied.

• Toxicological Research
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• v.22 no.4
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• pp.339-348
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• 2006

Misaengtang (MST), a formula of Korean herbal medicines, has been used as a weight-controlling recipe. We have investigated two experiment of body weight regulation by MST In rats. i) The anti-obesity effect of MTS on a high fat diet-induced obesity, male Sprague-Dawley rats were fed with a high-fat diet containing 30% in the absence or presence of MST (0.3, 1 or 3%) or a reference orlistat (0.05%) for 6 weeks. ii) weight-decrease effect of MST on normal diet, same animal were fed with a normal diet in the absence or presence of MST (3%) for 6 weeks. And the body weights, daily feed and water consumptions, organ weights, fat weights serum biochemistry were measured. In both experiments, MST and orlistat did not affect the body weight gain. But orlistat significantly increased the feed and water consumptions, leading to low-feed efficiency, and orlistat markedly reduced abdominal, paratesticular and perirenal fat weights, although increased the kidney weights. In MST, low dose (0.3%) of MST decreased the perirenal fat and increased the kidney weights in rats fed HFD, and MST 3% decreased the abdominal fat weights in rats fed normal diet. In addition, Orlistat caused changes in parameters of hepatotoxicity (AST and glucose), nephrotoxicity (BUN and B/C ratio) and lipid metabolism (HDL and triglycerides). In comparison, MST decreased AST, ALP and ALT, the hepatotoxicity markers, and somewhat improved the hepatic fatty degeneration. Taken together, it is suggested that MST does not exert anti-obesity activity as well as remarkably direct effects, but MST may be potentially benefit for dietary cure and exercise-cure of obesity.

• Journal of Sasang Constitutional Medicine
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• v.23 no.2
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• pp.263-274
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• 2011

1. Objectives: We report a series of 4 obesity cases who responded well to the weight-loss therapy based on the Taeeum Sasang constitutional therapy. 2. Methods: In treating 4 obese patients who were constitutionally typed as the Taeeum type, Case 1 and Case 2 fell into the category of the Lung Dry-Cold symptomatology, Case 3 into the Dry-Heat symptomatology, and Case 4 into the Exterior-Interior Combined symptomatology. Each patient was given Sasang medication according to protocol: Taeeumjowi-tang (Taiyintiaowei-tang) to Case 1 and Case 2, Cheongpyesagan-tang (Qingfeixiegan-tang) to Case 3, and Seunggijowi-tang (Chengqitiaowei-tang) to Case 4. On each visit to the clinic (7-21 times in total), the patients were checked on their general condition and change in body weight. 3. Results and Conclusions: All patients showed improvements in their general condition and a satisfactory decrease in weight (Case 1 showed a decrease of 12.7 kg in 84 days, Case 2 a decrease of 8.9 kg in 39 days, Case 3 a decrease of 33 kg in 250 days, and Case 4 a decrease of 29.3 kg in 155 days). Treating obesity based on Taeeum constitutional therapy was found to be effective for weight loss and general improvement of health. The sustained effects of the therapy should be checked during the following visits. The obesity treatment protocol suggested in this investigation should be explored and verified in future studies.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.2
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• pp.107-114
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• 2014

Objectives The purpose of this study is analyzing internal research trends of oriental obesity pattern identification in korean literature based on obesity pattern identification questionnaires, development and application of Pattern Identification System to help solve problems of future researches. Methods 6 Korean databases were searched for articles of oriental obesity pattern identification, irrespective of publication year and 13 studies were reviewed. An analytical method such as descriptive statistics and an actual number and percentage was used. Results We collected 13 studies. 4 studies were published in 2012 and 2008, the highest number of studies. 7 Clinical studies were the major research method. The Studies were classified according to the characteristics and design. 5 studies were about research of analysis and improvement of oriental obesity pattern identification questionnaire, the most number of studies. 4 studies were about research of observational studies in clinical on obesity pattern identification. 3 studies were about research of intervention studies in clinical on obesity pattern identification and 1 study was about clinical practice recommendation. Conclusions Establishment of obesity pattern identification system and its clinical application could lead to standardizing obesity pattern identification and clinical practice guideline. Applied on other diseases, obesity pattern identification system could also lead to improving treatment rate, contributing to the development of clinical practice guidelines and academic field of research.

• The Journal of Korean Medicine
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• v.19 no.2
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• pp.125-136
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• 1998

This study is on the etiological factors of the obesity, symptoms of a disease caused by the etiological factors and the method of medical treatment resulted from symptoms of a disease, it is based on Dong-Yi Bo Gam. The conclusion of this study is as follows. 1. The final metabolic of fat is depend on the defensive energy. The shape of fatty layer is changed by the point where the defensive energy is replenish or not. So 'Goin(暠人)' 'Bein(肥人)' and 'Yuckin(肉人)' is made a discriminated and there is defferent between 'Besudaeso(肥瘦大小)' and 'Herlqidaso(血氣多少)'. 2. Etiological factors of obesity is ; essential substance from cereals overcome the primodial energy, spleen and stomach are strong at once, spleen and stomach are weak at once, spleen is disturbed by evil energy, retention of phlegm and fluid, muscle is weak, blood is excess but energy (qi)is weak, hua-sid(華食) eating the sweat food very often, a rich fatty diet. 3. To investigate each syndrome as etiological factons, essential substance from cereals overcome primodial energy is divided into two case: one is the food increase itself because of the weakness of stomach energy (qi), the other is not to digest the food because liver overact spleen by seven emotion. The obesity because of strengthen of the spleen and stomach at once do not feel hungry very well and spleen and stomach do not damaged easily by overacting. The obesity because of weakness of spleen and stomach at once, and disturbace in spleen cause by evil energy, gain the weight even if they eat food a little. Also it is hard to move four limbs. Weakness of muscle is weakness of spleen and stomach. Weakness of muscle is caused by weakness of spleen and stomach. That is the case of faining the weight because of eating food with an empty stomach. The obsity caused by retention of fluid has intestine rumbling and gain the weight suddenly. 4. The method of medical treatment fallowing to the etiological factors: The food is inclined to increase itself caused by weakness of stomach energy, In case of the obseity caused by this phenomenon. We can use Decoction for Reinforcing Middle wanner and Replenishing Qi(補中益氣湯), five tastes il-going-san(左味異功散) and so on. The method of medical treatment on obsity caused by strengthen of spleen and stomach is not referred yet. But we must investigate about using peptic powder(平胃散), ji-chul-huan(枳朮丸) for strengthen of stomach qi (胃氣). If the obesity appear caused by weakness of spleen and stomach and disturbance in spleen as to evil energy, and in the same time stomach qi is weak, we can use li-gong san(異功散). If not only obesity but also indigestion, we can use Decoction for naurishing the stomach and promotion eating(養胃進食湯). If not only obesity but also weakness of spleen and stomach, we can use Decoction for Reinforcing Middle warmer and replenishing Qi(補中益氣湯). The energy being weak, we can use Decoction for six noble drugs(六君子湯). If the obesity appear because of retention of fluid, we can use sin-chul-huan(神朮丸). On the obesit, caused by excess of blood and weakness of qi(血管氣虛), there is not method of mectical treatment yet, but the method of medical treatment that we count of first important maybe to invigorate the spleen and the lung qi and to disperse and recitify the depressed liver energy(疏肝利氣). The method of medical treament about the obesity caused by a rich fatty diet is not mentioned yet, but it is important to improve the lifestyle of food and we think that invigorate the spleen, and the lung-qi(補疏肝氣) and disperse and recitify the depressed liver-energy (??肝利機) amy count of first important. 5.There is useful medicine for weight down for example Herb tea(茶), red bean, wax gourd, etc. 6.The etiological factors of the obesity that revive frequently is weakness of qi(氣虛), from 形成氣衰, deficiency of yang, hasty of qi, damp and so on. The symptoms and sign of a disease that revive frequently to the obesity is appoplexia(中風), leucorrhea, reddish and whitish turbid, feeling of fullness in the upper abdomen, diabetes and so on.

• The Journal of Pediatrics of Korean Medicine
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• v.27 no.4
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• pp.57-67
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• 2013

Objectives The purpose of this study is to investigate the safety and effect of Biman-tang (BMT) on two different administration periods in the treatment of childhood overweight and obesity. Methods In retrospective study, 39 overweight and obese ($85^{th}$ percentile ${\leq}$ Body Mass Index (BMI)) children were treated with BMT from January 2006 to April 2013 at Korean Medical Clinic in Suwon, Korea. The primary outcomes were the changes in BMI and Obesity Index (OI) from baseline to the treatment groups. Secondary outcomes included the changes in height, weight and safety of the medicine. Comparisons of BMI, OI, height and weight between the short-period (SP) treatment group and the long-period (LP) treatment group were done by using ANCOVA. Results The change of the mean of BMI ($-0.5{\pm}0.6kg/m^2$ vs $-1.4{\pm}0.8kg/m^2$, respectively; p=0.003) and OI ($-3.6{\pm}3.9%$ vs $-9.7{\pm}4.7%$, respectively; p<0.001) showed significant reduction both in SP (n=16) and LP treatment group (n=23). The mean height showed no significant difference in both groups. The mean weight of LP treatment group showed significant reduction compared to SP treatment group ($-0.2{\pm}1.3kg$ vs $-1.6{\pm}1.6kg$, respectively; p=0.006). Most of the children were compliant to the medication and no serious adverse events were found in two groups. Conclusions These findings emphasize that BMT is effective in the treatment of childhood obesity and it requires at least 45 days of treatment for the best result.