The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Comparisons of Effects of Biman-tang according to Administration Period in Childhood Obesity

비만환아에서 복약기간에 따른 비만탕의 치료효과 비교연구

  • Lim, Youngkwern (Dept. of Herbology, College of Korean Medicine, Kyung Hee University) ;
  • Min, Seorim (Dept. of Acupuncture and Moxibustion, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Heeman (Dept. of Herbology, College of Korean Medicine, Kyung Hee University) ;
  • Hur, Kwang-Wook (Dept. of Herbology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Hoon (Gangnam Inuri Korean Medical Clinic) ;
  • Lee, Jinsoo (Dept. of Korean Internal Medicine, Dongseo Yunghap Hospital) ;
  • Kim, Hocheol (Dept. of Herbology, College of Korean Medicine, Kyung Hee University) ;
  • Park, Jae-Woo (Dept. of Internal Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Park, Hi-Joon (Dept. of Acupuncture and Moxibustion, College of Korean Medicine, Kyung Hee University)
  • 임영권 (경희대학교 한의과대학 본초학교실) ;
  • 민서림 (경희대학교 한의과대학 경혈학교실) ;
  • 김희만 (경희대학교 한의과대학 본초학교실) ;
  • 허광욱 (경희대학교 한의과대학 본초학교실) ;
  • 이훈 (강남 아이누리 한의원) ;
  • 이진수 (동서융합병원 한방내과) ;
  • 김호철 (경희대학교 한의과대학 본초학교실) ;
  • 박재우 (경희대학교 한의과대학 내과학교실) ;
  • 박히준 (경희대학교 한의과대학 경혈학교실)
  • Received : 2013.10.25
  • Accepted : 2013.11.14
  • Published : 2013.11.30
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Abstract

Objectives The purpose of this study is to investigate the safety and effect of Biman-tang (BMT) on two different administration periods in the treatment of childhood overweight and obesity. Methods In retrospective study, 39 overweight and obese ($85^{th}$ percentile ${\leq}$ Body Mass Index (BMI)) children were treated with BMT from January 2006 to April 2013 at Korean Medical Clinic in Suwon, Korea. The primary outcomes were the changes in BMI and Obesity Index (OI) from baseline to the treatment groups. Secondary outcomes included the changes in height, weight and safety of the medicine. Comparisons of BMI, OI, height and weight between the short-period (SP) treatment group and the long-period (LP) treatment group were done by using ANCOVA. Results The change of the mean of BMI ($-0.5{\pm}0.6kg/m^2$ vs $-1.4{\pm}0.8kg/m^2$, respectively; p=0.003) and OI ($-3.6{\pm}3.9%$ vs $-9.7{\pm}4.7%$, respectively; p<0.001) showed significant reduction both in SP (n=16) and LP treatment group (n=23). The mean height showed no significant difference in both groups. The mean weight of LP treatment group showed significant reduction compared to SP treatment group ($-0.2{\pm}1.3kg$ vs $-1.6{\pm}1.6kg$, respectively; p=0.006). Most of the children were compliant to the medication and no serious adverse events were found in two groups. Conclusions These findings emphasize that BMT is effective in the treatment of childhood obesity and it requires at least 45 days of treatment for the best result.

Keywords

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