• Title/Summary/Keyword: New directions

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Transarterial Therapies for Hepatocellular Carcinoma: a Comprehensive Review with Current Updates and Future Directions

  • Kumar, Yogesh;Sharma, Pranav;Bhatt, Neeraj;Hooda, Kusum
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.2
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    • pp.473-478
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    • 2016
  • Hepatocellular cancer is a very common cause of cancer related deaths worldwide. Only 30-40% of patients present with early-stage disease open to curative treatments, such as resection or transplantation, while others can only undergo local therapies or palliative care. Various trans-arterial approaches have been used for treatment of hepatocellular carcinoma in patients who need a down-staging to liver transplantation, and who are not candidates for transplantation or radiofrequency ablation. Transarterial chemoembolization (TACE), transarterial embolization (TAE), drug-eluting beads, and radioembolization have been used for locoregional control, and have been shown to prolong the overall survival when compared with supportive care. In this review, we discuss patient selection, pre- and post-procedure imaging, techniques, safety, and clinical outcomes related to these therapies. Newer advances with future directions in various fields related to trans-arterial therapies are also discussed.

The Future Direction of Home Economics (가정학의 방향)

  • 강혜원
    • Journal of the Korean Home Economics Association
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    • v.18 no.2
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    • pp.57-62
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    • 1980
  • This paper is a review of articles selected from Journal of Home economics (1973~1979) with the purpose of studying new direction of home economics in america. Regarding the future of home economics in America. Regarding the future of home economics, the following points were important : 1) Top priorities for future directions in home economics were developed at the 11th Lake Placid Conference and published in "Home Economics New Directions 11" (May 1975). 2) A new definition of home economics by University of Arizona students described the uniqueness of home economics clearly, and in easily understandable terms. 3) A human ecosystem model which depicts human beings existing I interaction with the total environment was found to be a new approch to the concept of home economics. 4) A proposal was made for offering home economics courses to students in professional human service fields. Some of the problems of home economics which need to be solved: 1) The emphasis on specialization in a major field has made home economics just a collection of specialities. 2) The change of the designation "home economics" to other lables by some institutions has brought confusion. 3) Inadequate supply of competent faculty is the cause of inactive home economics research. 4) Teaching sex defined roles is outdated. The above findings give insights to Korean home economics which is faced with a variety of problems in a rapidly changing society.

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Policy Directions for Human Resources Development in the New Growth Engine Industries Based on the Analysis of the U.S. Green Job Training Framework (미국의 그린직업훈련체계 분석을 통한 우리나라 신성장동력분야 인력양성 정책방향 도출)

  • Om, Kiyong;Lee, Moonsu;Kwon, Oh-Young;Rim, Kyung-Hwa
    • The Journal of Korean Institute for Practical Engineering Education
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    • v.4 no.1
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    • pp.119-131
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    • 2012
  • This study investigated the U.S. green job training framework and specific training programs designed to respond to diverse green skill needs of industry at the federal and state level, and looked for policy directions for improving governmental job training programs in the field of new growth engine industries of Korea. As with any training program, training programs for green jobs should be responsive to the particular economic growth potential, employer needs, and workforce realities in a given country or region. The findings of the study are expected to contribute to enhancing the effectiveness of the Korean job training programs in the new growth engine industries.

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A new model for T-shaped combined footings part I: Optimal dimensioning

  • Luevanos-Rojas, Arnulfo;Lopez-Chavarria, Sandra;Medina-Elizondo, Manuel
    • Geomechanics and Engineering
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    • v.14 no.1
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    • pp.51-60
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    • 2018
  • The foundations are classified into shallow and deep, which have important differences: in terms of geometry, the behavior of the soil, its structural functionality, and its constructive systems. The shallow foundations may be of various types according to their function; isolated footings, combined footings, strip footings, and slabs foundation. The isolated footings are of the type rectangular, square and circular. The combined footing may be rectangular, trapezoidal or T-shaped in plan. This paper presents a new model for T-shaped combined footings to obtain the most economical contact surface on the soil (optimal dimensioning) to support an axial load and moment in two directions to each column. The new model considers the soil real pressure, i.e., the pressure varies linearly. The classical model uses the technique of test and error, i.e., a dimension is proposed, and subsequently, the equation of the biaxial bending is used to obtain the stresses acting on each vertex of the T-shaped combined footing, which must meet the conditions following: The minimum stress should be equal or greater than zero, and maximum stress must be equal or less than the allowable capacity that can withstand the soil. To illustrate the validity of the new model, numerical examples are presented to obtain the minimum area of the contact surface on the soil for T-shaped combined footings subjected to an axial load and moments in two directions applied to each column.

A Survey of Security and Privacy Challenges in Cloud Computing: Solutions and Future Directions

  • Liu, Yuhong;Sun, Yan Lindsay;Ryoo, Jungwoo;Rizvi, Syed;Vasilakos, Athanasios V.
    • Journal of Computing Science and Engineering
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    • v.9 no.3
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    • pp.119-133
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    • 2015
  • While cloud computing is gaining popularity, diverse security and privacy issues are emerging that hinder the rapid adoption of this new computing paradigm. And the development of defensive solutions is lagging behind. To ensure a secure and trustworthy cloud environment it is essential to identify the limitations of existing solutions and envision directions for future research. In this paper, we have surveyed critical security and privacy challenges in cloud computing, categorized diverse existing solutions, compared their strengths and limitations, and envisioned future research directions.

Direct Search Methods for Nonlinear Optimization Problem used ART Theory

  • Son, Jun-Hyeok;Seo, Bo-Hyeok
    • Proceedings of the KIEE Conference
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    • 2006.07d
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    • pp.1830-1831
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    • 2006
  • In this paper, the search is conducted along each of the coordinate directions for finding the minimum. If $e_i$ is the unit vector along the coordinate direction i, we determine the value a, minimizing f(a)= $f(x+ae_i)$, where a is a real number. A move is made to the new point $x+a_ie_i$ at the end of the search along the direction i. In an n dimensional problem, we define the search along all the directions as one stage. The function value at the end of the stage is compared to the value at the beginning of the stage in establishing the convergence. The gradient appears to be zero at point. We can safeguard this by introducing an acceleration step of one additional step along the pattern direction developed by moves along the coordinate directions.

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RECONSTRUCTION OF LIMITED-ANGLE CT IMAGES BY AN ADAPTIVE RESILIENT BACK-PROPAGATION ALGORITHM

  • Kazunori Matsuo;Zensho Nakao;Chen, Yen-Wei;Fath El Alem F. Ah
    • Proceedings of the IEEK Conference
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    • 2000.07b
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    • pp.839-842
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    • 2000
  • A new and modified neural network model Is proposed for CT image reconstruction from four projection directions only. The model uses the Resilient Back-Propagation (Rprop) algorithm, which is derived from the original Back-Propagation, for adaptation of its weights. In addition to the error in projection directions of the image being reconstructed, the proposed network makes use of errors in pixels between an image which passed the median filter and the reconstructed one. Improved reconstruction was obtained, and the proposed method was found to be very effective in CT image reconstruction when the given number of projection directions is very limited.

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A Basic Study on the Formation of Digital Korean Studies Center (디지털 한국학센터 구축에 관한 기초 연구)

  • Kim, Sung-Hyuk;Lee, Hye-Jin
    • Journal of the Korean Society for Library and Information Science
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    • v.35 no.3
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    • pp.135-150
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    • 2001
  • This paper is proposed a construction directions of digital Korean study center for Korean cultural and historical materials. It was reviewed and analyzed for findings construction directions in domestic and abroad Web sites such as The Academy of Korean Studies, National History Compilation Committee, Seoul National University and Tufts University in the USA. The paper was recommended and guided new research directions for the construction of the digital Korean study center, and suggested some findings through comparative analysis for the center.

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Problems of Employment of the Population and Directions of Their Regulation in the Conditions of War

  • Zakharchyn, Galyna;Antonov, Andriі;Voityk, Oleksandra;Plotka, Lyubov;Mirko, Nataliia
    • International Journal of Computer Science & Network Security
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    • v.22 no.11
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    • pp.303-307
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    • 2022
  • The purpose of the study is to determine the key aspects of the problems of employment of the population and the directions of their state regulation in war conditions. Employment policy involves a system of measures to create conditions for a more complete use of the potential of labor and business activity of the able-bodied population, linking this activity through taking into account the specifics of group interests with the tasks and guidelines for socio-economic development. But in the conditions of war, this problem acquires a new relevance. For the study, a number of theoretical methods of analysis were used. Based on the results of the study, the key aspects of the problems of employment of the population and the directions of their state regulation in war conditions were identified.

Cancer Gene Therapy. History and Major Developments (암 유전자 치료제의 개발 현황)

  • 정인재
    • Toxicological Research
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    • v.19 no.3
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    • pp.247-257
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    • 2003
  • Medicine is undergoing a revolution in the understanding of the mechanisms through which disease processes develop. The advent of genetics and molecular biology to oncology not only is providing surrogate predictors of therapy response and survival which are forming the basis for selection among established treatment options, but is providing targets for new directions in therapy as well. Molecular modification of somatic cells for the purposes of protecting the normal cells from the toxicity of cancer chemotherapy, for the sensitization of the tumor cells to therapy and use of conditionally replicating viral vector have been new directions of cancer treatment which have reached the clinical arena. Advances in molecular pharmacology and vector design summarized in this paper may provide solutions to some of the existing problems in the technology of gene transfer therapy. Continued basic research into the biological basis of human disease, systemic studies of the application of these discoveries to therapy and the improvement of vector for gene delivery all combined may result in advances in this important field of therapy over the next few years.