• Journal of Convergence for Information Technology
• /
• v.10 no.3
• /
• pp.76-91
• /
• 2020

Whole genome sequence of Abeliophyllum distichum Nakai (Oleaceae) cultivar Ok Hwang 1 Ho, which is Korean endemic species, was recently sequenced to understand its characteristics. Acteoside is one of major useful compounds presenting various activities, and its several proposed biochemical pathways were reviewed and integrated to make precise biochemical pathway. Utilizing MetaPre-AI^TM which was developed for predicting secondary metabolites based on whole genome with the precise biochemical pathway of acteoside and the InfoBoss Pathway Database, we successfully rescued all enzymes involved in this pathway from the genome sequences, presenting that A. distichum cultivar Ok Hwang 1 Ho may produce acteoside. High-performance liquid chromatography result displayed that callus of A. distichum cultivar Ok Hwang 1 Ho contained acteoside as well as isoacteoside which may be derived from acteoside. Taken together, we successfully showed that MetaPre-AI^TM can predict secondary metabolite from plant whole genomes. In addition, this method will be efficient to predict secondary metabolites of many plant species because DNA can be analyzed more stability than chemical compounds.

• Child Health Nursing Research
• /
• v.29 no.3
• /
• pp.161-165
• /
• 2023

• Korea Trade Review
• /
• v.46 no.2
• /
• pp.371-387
• /
• 2021

This paper analyzed 110 papers related to the field of trade settlement published in the Korea Trade Review for 40 years from 1980 to 2019. This study tried to provide an insight on research topics and to suggest future research directions. The papers were analyzed according to the detailed topics of trade settlement. Research trends were identified every ten years by investigating the most frequently used titles and keywords. The analysis found that the direction of the research changed in line with the changes in trade settlement practices. Future research lies in the field of electronicization of traditional settlement methods, search for alternative settlement methods, individual international microtransaction and trade fraud.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.5
• /
• pp.2415-2421
• /
• 2016

E-cadherin (CDH1) genetic variations alter gene transcriptional activity of epithelial cells in vitro and may cause susceptibility to various cancers. Associations of CDH1 -160C>A polymorphism with various cancers have been widely reported. However, the results are controversial and inconsistent. To derive a more accurate estimation of the relationship, a meta-analysis was performed with regard to gastrointestinal (GI) cancer risk. Eligible studies were identified through a search of PubMed database until December 2015. Associations between the CDH1 -160C>A polymorphism and GI cancer risk was considered by odds ratios (ORs) together with their 95% confidence intervals (CIs). A total of 31 studies including 11,606 cases and 12,655 controls were involved in this meta-analysis. Overall, this meta-analysis showed no association between CDH1 -160C>A polymorphism and GI cancer risk (A vs. C: OR = 1.08, 95%CI = 0.98-1.18, P = 0.086;CA vs. CC: OR = 1.09, 95%CI = 0.97-1.22, P = 0.118; AA vs. CC: OR = 1.10, 95%CI = 0.89-1.35, P = 0.356; AA vs. CC + CA: OR = 1.06, 95%CI = 0.96-1.18, P = 0.207; CA+AA vs. CC: OR = 1.01, 95%CI = 0.84-1.22, P = 0.89). In subgroup analysis, similar results were found. In conclusion, this meta-analysis has demonstrated that there is a lack of association of the CDH1-160C>A polymorphism with GI cancer susceptibility.

• Journal of the Korean Ceramic Society
• /
• v.47 no.3
• /
• pp.223-231
• /
• 2010

The serious issue of tall building is to ensure the fire-resistance of high strength concrete. The fire resistant finishing method is necessarily essential in order to satisfy the fire resistance time of 3 h required by the law. The fire resistant finishing method is installed by applying a fire resistant material as a method of shotcrete or a fire resistant board to high strength concrete surface. This method can reduce the temperature increase of the reinforcement embedded in high strength concrete at high temperature due to the installation thickness control. This study is interested in identifying the effectiveness of inorganic alumino-silicate compounds including the inorganic admixture such as fly ash and meta-kaolin as the fire resistant finishing materials through the analysis of fire resistance and components properties at high temperature. The study results show that the fire resistant finishing material composed of fly ash and meta-kaolin has the thermal stability of the slight decrease of compressive strength at high temperature. These thermal stability is caused by the ceramic binding capacity induced by alkali activation reaction by the reason of the thermal analysis result not showing the decomposition of calcium hydrate. Inorganic compounds composed of fly ash and meta-kaolin is evaluated to be very effective as the fire resistance material for finishing to protect the concrete substrate by the reason of those simplicity in both application and manufacture. The additional study about the adhesion in the interface with concrete substrate is necessary for the purpose of the practical application.

• Journal of the Korean Society for Library and Information Science
• /
• v.43 no.4
• /
• pp.117-137
• /
• 2009

This study aims to grasp how to understand the difference in return on investment (ROI) or the cost-benefit ratio in forty-two domestic and overseas studies of library valuation, using a meta-analytical review method. Meta-analysis, a quantitative analysis on the findings of previous studies, was conducted to gather the general findings and lessons from prior empirical research. The results of meta-regression analysis indicate that the pattern of findings is consistent with our expectations regarding the effect of benefit scope and per capita GDP included in the ROI figure. This study appears to be the first meta-analytical review conducted on library valuations and the findings provide strong implications for the policy-making process.

• The KIPS Transactions:PartA
• /
• v.13A no.6 s.103
• /
• pp.533-540
• /
• 2006

This paper describes the design and implementation of a grid system META (Metacomputing Environment using Test-run of Application) which facilitates the execution of a CFD (Computational Fluid Dynamics) analysis program on distributed environment. The grid system META allows the CFD program developers can access the computing resources distributed over the network just like one computer system. The research issues involved in the grid computing include fault-tolerance, computing resource selection, and user-interface design. In this paper, we exploits an automatic resource selection scheme for executing the parallel SPMD (Single Program Multiple Data) application written in MPI (Message Passing Interface). The proposed resource selection scheme is informed from the network latency time and the elapsed time of the kernel loop attained from test-run. The network latency time highly influences the executional performance when a parallel program is distributed and executed over several systems. The elapsed time of the kernel loop can be used as an estimator of the whole execution time of the CFD Program due to a common characteristic of CFD programs. The kernel loop consumes over 90% of the whole execution time of a CFD program.

• Journal of Korean Clinical Nursing Research
• /
• v.25 no.3
• /
• pp.221-236
• /
• 2019

Purpose: The purpose of this study was to systematically review and identify factors relevant to the positive psychological capital of clinical nurses. Methods: These was no limit on year of publication. Articles related to Korean clinical nurses were retrieved from computerized database using a manual search. A systematic review was conducted based on the PRISMA flow. The total correlational effect size (ESr) for each related factor was calculated from Fisher's Zr. Funnel plots, fail-safe numbers, and Egger regression tests were used to evaluate publication bias in meta-analysis studies. The correlational effect size of 25 studies was analyzed through meta-analysis using Comprehensive Meta-Analysis software 3.0 (CMA). Results: The review included 25 studies. In the systematic review, 14 demographic factors and 46 organizational factors were found to be influential. Eleven factors (6 demographic factors and 5 organizational factors) were appropriate for meta-analysis. The overall effect size was .26. The demographic total correlation effect size of related factors was .20 and the total effect size of organization was .46. Organizational commitment (ESr=.38) and job satisfaction (ESr=.54) were statistically positively related variables. Negative variables were burnout (ESr=-.61), turnover intention (ESr=-.41) and workplace bullying (ESr=-.33). The total effect size of the organizational factors was larger than the demographic total effect size. There was no publication bias except for demographic variables. Conclusion: Organizational factors and adjustable variables have a significant impact on positive psychological capital. The results of this study support the need for development of interventions focusing on organizational factors.

• The Journal of Internal Korean Medicine
• /
• v.42 no.4
• /
• pp.672-686
• /
• 2021

Objectives: The purpose of this study is to assess the efficacy and safety of Baekhogainsam-tang for type 2 diabetes without complications by systemic review and meta-analysis of randomized controlled trials (RCTs). Methods: For a systematic review and meta-analysis, we set a key question in accordance with PICOT-SD. We searched the following up to March 31. 2021: PubMed, EMBASE, The Cochrane Library, CNKI, CiNii, KISS, KMBASE, OASIS, and ScienceON. A meta-analysis was conducted by synthesizing the results, including fasting plasma glucose level, postprandial 2-hour plasma glucose level, and Glycated Hemoglobin (HbA1c). Results: A total of five trials are included in this systemic review. The treatment group (Baekhogainsam-tang plus conventional treatment) showed more statistically significant effect than did the control group (conventional treatment only) in fasting plasma glucose level, postprandial 2-hour plasma glucose level, and glycated hemoglobin (HbA1c). Conclusions: Baekhogainsam-tang showed statistically significant effects in hypoglycemic effect and in improving insulin resistance. However, the number of studies included in the meta-analysis was insufficient, and the BIT used in the included studies was not standardized. This topic requires further attention and more clinical research.

• Nutrition Research and Practice
• /
• v.15 no.3
• /
• pp.329-345
• /
• 2021

BACKGROUD/OBJECTIVES: Evidence has suggested an association between serum vitamin D and metabolic syndrome (MetS), but prospective studies are very limited. The objective was to assess the dose-response association between serum vitamin D concentration and MetS risk using a systematic review and meta-analysis of updated observational studies. MATERIALS/METHODS: Using MEDLINE, PubMed, and Embase, a systematic literature search was conducted through February 2020 and the references of relevant articles were reviewed. A random-effects model was used to estimate the summary odds ratio/relative risk and 95% confidence interval (CI). Heterogeneity among studies was evaluated with I² statistic. In total, 23 observational studies (19 cross-sectional studies, and four cohort studies) were included in the meta-analysis. RESULTS: The pooled estimates (95% CI) for MetS per 25-nmol/L increment in serum vitamin D concentration were 0.80 (95% CI, 0.76-0.84; I² = 53.5) in cross-sectional studies, and 0.85 (95% CI, 0.72-0.98; I² = 85.8) in cohort studies. Similar results were observed, irrespectively of age of study population, study location, MetS criteria, and adjustment factors. There was no publication bias for the dose-response meta-analysis of serum vitamin D concentrations and MetS. CONCLUSIONS: Dose-response meta-analysis demonstrated that a 25-nmol/L increment in the serum vitamin D concentration was associated with 20% and 15% lower risks of MetS in cross-sectional studies and cohort studies, respectively.