• 제목/요약/키워드: Medical informatics

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Study on the Five Tastes in the Yellow Emperor's Canon of Internal Medicine

  • 문영옥;안민섭;박진수;김훈영;이시형;금경수;박민철;조은희
    • 동의생리병리학회지
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    • 제23권6호
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    • pp.1247-1260
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    • 2009
  • This dissertation aims to study the five tastes in the Yellow Emperor's Canon of Internal Medicine. Medicinals as well as Foods are classified by the five tastes: sweet, sour, bitter, salty and pungent, which can be tasted by the tongue. With the development of the theory dealing with the medicinal properties, some flavors are summarized out of clinical actions of medicinals, therefore, there is a little difference between the flavors of medicinal herbs and the tastes got by tongue. Each taste acts on or has direct influence on a specific vital organ, and each of which has different physiologic actions. Taste also has a long-term or post digestive effect on the body and its metabolism. When each taste is consumed in moderation, it benefits the corresponding organ. Over-indulgence in any taste harms the organ and creates imbalance among the five vital organ systems. The Korean medicinal herbs with same flavor mostly possess similar actions while the medicinal herbs with different flavors show different actions in the treatment, which are shown as follows. Sour has absorbing, consolidating and astringent actions and acts on the liver. Bitter has the actions of drying or resolving dampness, purging and lowering and acts on the heart. Sweet has the nourishing, harmonizing and moistening actions and acts on the spleen. Pungent has an action of dispersing and promoting circulation of gi and blood and acts on the lungs. Salty has the effects of softening hard nodes or masses and promoting defecation, etc and acts on the kidneys. The five organ systems control and support each other. Proper coordination only exists when there is no one organ stronger or weaker than the rest. Since the five tastes have direct influences on the five organs, the diet we take should have a good combination of the five tastes in order to promote internal balance and harmony. They control our well-being and create dietary balance. Excessive consumption of any of these could result in adverse effects. In a word, when the properties of the five tastes respectively are distinguished, their natures and flavors cannot be separately considered. I think the harmonization of food and medicinals should be stressed on good nutritional diet to maintain good health. The traditional belief that food and medicine share the same origin is a part of Korean medicine tradition.

Peroxisome Proliferator-Activated Receptor-Gamma Agonist 4-O-Methylhonokiol Induces Apoptosis by Triggering the Intrinsic Apoptosis Pathway and Inhibiting the PI3K/Akt Survival Pathway in SiHa Human Cervical Cancer Cells

  • Hyun, Seungyeon;Kim, Man Sub;Song, Yong Seok;Bak, Yesol;Ham, Sun Young;Lee, Dong Hun;Hong, Jintae;Yoon, Do Young
    • Journal of Microbiology and Biotechnology
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    • 제25권3호
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    • pp.334-342
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    • 2015
  • 4-O-Methylhonokiol (MH), a bioactive compound derived from Magnolia officinalis, is known to exhibit antitumor effects in various cancer cells. However, the precise mechanism of its anticancer activity in cervical cancer cells has not yet been studied. In this study, we demonstrated that MH induces apoptosis in SiHa cervical cancer cells by enhancing peroxisome proliferator-activated receptor-gamma (PPARγ) activation, followed by inhibition of the PI3K/Akt pathway and intrinsic pathway induction. MH upregulated PPARγ and PTEN expression levels while it decreased p-Akt in the MH-induced apoptotic process, thereby supporting the fact that MH is a PPARγ activator. Additionally, MH decreased the expression of Bcl-2 and Bcl-XL, inducing the intrinsic pathway in MH-treated SiHa cells. Furthermore, MH treatment led to the activation of caspase-3/caspase-9 and proteolytic cleavage of polyADP ribose polymerase. The expression levels of Fas (CD95) and E6/E7 oncogenes were not altered by MH treatment. Taken together, MH activates PPARγ/PTEN expression and induces apoptosis via suppression of the PI3K/Akt pathway and mitochondria-dependent pathways in SiHa cells. These findings suggest that MH has potential for development as a therapeutic agent for human cervical cancer.

Conceptual Retrieval of Chinese Frequently Asked Healthcare Questions

  • Liu, Rey-Long;Lin, Shu-Ling
    • International Journal of Knowledge Content Development & Technology
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    • 제5권1호
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    • pp.49-68
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    • 2015
  • Given a query (a health question), retrieval of relevant frequently asked questions (FAQs) is essential as the FAQs provide both reliable and readable information to healthcare consumers. The retrieval requires the estimation of the semantic similarity between the query and each FAQ. The similarity estimation is challenging as semantic structures of Chinese healthcare FAQs are quite different from those of the FAQs in other domains. In this paper, we propose a conceptual model for Chinese healthcare FAQs, and based on the conceptual model, present a technique ECA that estimates conceptual similarities between FAQs. Empirical evaluation shows that ECA can help various kinds of retrievers to rank relevant FAQs significantly higher. We also make ECA online to provide services for FAQ retrievers.

개인정보 보호에 대한 의료기관 종사자들의 지식, 인식과 실천 (Hospital Employees' Knowledge, Recognition and Practice on the Protection of Personal Information)

  • 정지나;문인오
    • 대한한의정보학회지
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    • 제21권1호
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    • pp.1-13
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    • 2015
  • The aim of this study was to investigate hospital employees' knowledge, recognition and practice on the protection of personal information. A total of 250 hospital employees were selected using convenient sampling in J province. The data were collected using self-reported questionnaire and were analyzed using SPSS 18.0 program and descriptive statistics, Chi-squire test, t-test, ANOVA, and Pearson correlation coefficients. Average score for knowledge, recognition and practice were significantly associated with gender, education, hospital size and there was a correlation among knowledge, recognition and practice. The results of this study will help to develop education program on the protection of personal information for hospital employees.

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"영추경(靈樞經)" 의 사혈요법(瀉血療法)에 대한 고찰(考察) (A Study on the Blood-Letting Therapy of "Lingshu")

  • 전학수;권해경;이시형
    • 대한한의정보학회지
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    • 제16권1호
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    • pp.75-103
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    • 2010
  • Lingshu, discusses acupuncture therapy in great detail. And there are many aspects in the book devoted to acupuncture, especially acupuncture description is rather and more organized. The book establishes the theory of meridians which explains the roots of meridians in details, and points out the location of acupoints and describes the standard of how to locates acupoints, sets forth nine kinds of needles and their uses. It lays thetheoretical foundation of Korean Medicine. This article could help improve the understanding of the blood-letting therapy in "Lingshu" and also paves the way for applying the therapy to treatment of the various diseases.

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"동의보감(東醫寶鑑)" "외형편(外形篇)" 골문(骨門) 인용문(引用文)에 대(對)한 고찰(考察) (A Review on quotations in chapter of bone, Wehyungpyun, Dongeuibogam)

  • 권해경;송지청;조은희
    • 대한한의정보학회지
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    • 제16권1호
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    • pp.135-139
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    • 2010
  • Quotations in "Dongeuibogam" are originated from books of Oriental Medicine. Those are exactly same with original books. However, some quotations are not in same comparing to original books. Authors are in concerns that the original sentences which are quoted in "Dongeuibogam" are how different and how similar or same, with comparing methods between them. As a result, we could find out original sentences in original books and we could make comparison between those and quotations of chapter of bone in "Wehyungpyun", "Dongeuibogam". Also we could get explanations of qoutations' accuracies.

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피로 호소 환자의 전신 체열 특성 (Thermographic analysis of body surface temperature of patient with fatigue)

  • 윤탁현;이호영;주종천
    • 대한한의정보학회지
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    • 제19권1호
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    • pp.36-42
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    • 2013
  • Background : The aim of this study is assessing the adaption of thermography for fatigue. Method : Thermography was accomplished in three group classified fatigue group with disease, fatigue group without disease, non-fitigue group without disease. Results : Temperatures of fatigue group with disease was lower than those of the other groups. Conclusion : Thermography can be used to diagnosing and assessing the fatigue patients.

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Brain Hologram Visualization for Diagnosis of Tumors using Graphic Imaging

  • Nam, Jenie;Kim, Young Jae;Lee, Seung Hyun;Kim, Kwang Gi
    • Journal of Multimedia Information System
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    • 제3권3호
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    • pp.47-52
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    • 2016
  • This research paper examines the usage of graphic imaging in Holographic Projections to further advance the medical field. It highlights the importance and necessity of this technology as well as avant-garde techniques applied in the process of displaying images in digital holography. This paper also discusses the different types of applications for holograms in society today. Different tools were utilized to transfer a set of a cancer patient's brain tumor data into data used to produce a 3D holographic image. This image was produced through the transfer of data from one program to another. Through the use of semi-automatic segmentation through the seed region method, we were able to create a 3D visualization from Computed Tomography (CT) data.

목통의 기원 및 사상의학적 효능 고찰 (Consideration on Origin and Efficiency in Sasang Constitutional Medicine of Mu tong)

  • 김명;유승엽;주종천
    • 대한한의정보학회지
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    • 제20권1호
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    • pp.1-8
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    • 2014
  • Objectives: This study aimed to find out the origin, efficiency in sasang constitutional medicine and dosage of Mu tong. Methods: Investigation and analysis was been done through 15 literatures like the pharmacopoeia of the five countries in east Asia, the literatures about sasang constitutional medicine and so on. Results and conclusion: The species of Mu tong in Korea is identical with the Mu tong in China, but different from Chuan mu tong and Guan mu tong in China. Mu tong is a kind of medicine using by kidney can be use at most 12 qian (about 45g) a day when treating heat closing in small intestine, edema, headache, dysentery and difficult urination on Soyangin(SY).

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불안을 동반한 수면 장애 환자 치험 1례 (A Case Report of Sleep Disorder with Anxiety)

  • 홍남중;금창준;박현민;이제균
    • 대한한의정보학회지
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    • 제19권2호
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    • pp.29-37
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    • 2013
  • Objectives: This case report presents a 29-years-old male patient. His chief complaint was insomnia, anxiety and chest discomfort. We diagnosed him with sleep disorder. During the therapeutic period, he experienced temporary improvement. Methods: We treated him with emotional freedom techniques(EFT), giungoren-therapy. Also, acupuncture and chuna therapy were accessorily practiced. The effects of treatment were measured by Beck depression inventory(BDI), state-trait anxiety inventory(STAI), insomnia severity index(ISI). Results: After treatment, the chief complaint have been subsided and improved. But, BDI, STAI, ISI score were not remarkably decreased. Conclusions: This result suggests that EFT and giungoren-therapy might be effective for sleep disorder patient with anxiety.

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