• 전자공학회논문지B
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• 제30B권7호
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• pp.83-91
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• 1993

A ghost cancelling method using the multiplicationless adaptive multipath channel identification is proposed. The IIR filter and the LMS algorithm are used for ghost cancelling. The coefficients of IIR filter are obtained by multipath channel identification. The LMS algorithm which is simple relatively is used as the adaptive algorithm. An MPS is selected as the reference signal and it is used as the input of the adaptive algorithm for the multipath channel identification. If an MPS is not exist, the horizontal syne, and color burst signal can be used as the reference signal. Improving of accuracy of the ghost cancelling in the presence of the phase variation in the multipath channel, a complex processing are also performed.

• 한국해양공학회지
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• 제21권6호
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• pp.53-58
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• 2007

A particle method, recognized as one of gridless methods, has been developed to investigate non-linear free-surface motions interacting with structures. This method is more feasible and effective than conventional grid methods for solving flow fieldswith complicated boundary shapes. The method consists of particle interaction models representing pressure gradient, diffusion, incompressibility, and the free-surface boundary conditions without grids. In the present study, broken dam problems with various viscosity values are simulated to validate the developed method.

• 대한임상전기생리학회지
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• 제2권1호
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• pp.1-8
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• 2004

This study was conducted to assess the effect of transcutaneous electrical nerve stimulation(TENS) and interferential current(IFC) in the patients with myofascial pain syndrome(MPS) on upper trapezius. Twenty patients with MPS on upper trapezius was assigned randomly to TENS group(n=10), IFC group(n=10). In TENS group, TENS was applied to the trigger point. In IFC group, IFC was applied to the trigger point. Duration of treatment was 2 weeks. Effects were assessed before treatment, post treatment by visual analogue scale(VAS), and pain rating score(PRS). Significant change of VAS was noticed in TENS group and IFC group. Significant change of PRS was noticed in TENS group and IFC group. IFC groups were significantly higher than TENS group that of the VAS and PRS. These result showed that IFC is effective treatment method for pain control in patients with MPS.

• International Journal of Naval Architecture and Ocean Engineering
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• 제13권1호
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• pp.575-584
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• 2021

This study contains the process of developing a Mission Planning System (MPS) of an USV that can be applied in real situations and verifying them through HILS. In this study, we set the scenario of a single USV with limited operating time. Since the USV may not perform some missions due to the limited operating time, an objective function was defined to maximize the Mission Achievement Rate (MAR). We used a genetic algorithm to solve the problem model, and proposed a method using a 3-D population. The simulation showed that the probability of deriving the global optimal solution of the mission planning algorithm was 96.6% and the computation time was 1.6 s. Furthermore, USV showed it performs the mission according to the results of the MPS. We expect that the MPS developed in this study can be applied to the real environment where USV performs missions with limited time conditions.

• 한국수자원학회논문집
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• 제34권6호
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• pp.605-615
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• 2001

수치시뮬레이션 기법 중 하나인 SMAC법은 시간의 변화에 따른 유동의 현상을 해석하기 위해 MAC법을 수정 한 기법이다. 비압축 점성 흐름을 풀기 위해 Navier-Stokes 방정식을 사용하였으며, 유동을 가시화하기 위해 마커입자가 사용되었다. 본 연구에서는 SMAC법을 사용한 2차원 물기등 붕괴현상의 수치시뮬레이션을 수행하였으며, 시뮬레이션 결과는 Martin과 Moyce의 실험 결과 및 MPS법의 계산결과와 비교하였고, 좋은 결과가 얻어졌다. 또한, 이 수치시뮬이션은 댐 붕괴와 같은 수공구조물의 붕괴현상에 적용할 수 있겠다.

• 한국해양공학회지
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• 제22권2호
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• pp.20-27
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• 2008

A moon-pool is a vertical well in a floating barge, drilling ship, or offshore support vessel. In this study, numerical simulation of two-dimensional moon-pool flaw coupled with a ship's motion in waves is carried out using a particle method, the so-called MPS method. The particle method, which is recognized as one of the gridless methods, was developed to investigate nonlinear free-surface motions interacting with structures. The method is more feasible and effective than convectional grid methods in order to solve a flaw field with complicated boundary shapes.

• Clinics in Shoulder and Elbow
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• 제20권3호
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• pp.138-146
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• 2017

Background: Arthroscopic fixations for large and comminuted bony Bankart lesions are technically difficult. We developed an arthroscopic multiple pulled suture (MPS) technique to restore large and comminuted bony Bankart lesions. Methods: Ten patients (mean age, 49.8 years; range, 31-79 years) underwent bony Bankart repair using the illustrated MPS technique and were then followed for a mean of 27.3 months. A plain radiograph series and three-dimensional computed tomography scans were taken at the initial clinical evaluation and 3 months postoperatively. Outcome measurements included the American Shoulder and Elbow Surgeons (ASES) score, Rowe score, University of California at Los Angeles (UCLA) score, and subjective patient satisfaction, along with surgical complications. Results: Union of an osseous fragment with the glenoid rim was confirmed in all patients on a computed tomography scan 3 months after operation. The osseous fragment was restored to proper articular congruence and reduction. The affected shoulder was stable in nine of the 10 patients. One patient presented with a redislocation after a sports injury 3 years postoperatively. The ASES, Rowe, and UCLA scores improved at the final evaluation, and median patient satisfaction at the final follow-up was 9 of 10 points (range, 6-10 points). Conclusions: The arthroscopic MPS technique for bony Bankart lesions with large or comminuted osseous fragments was a relatively easy and safe method for stable fixation of the osseous fragment. Therefore, the arthroscopic MPS technique resulted in good restoration of stability with high patient satisfaction and low complication rates.

• Journal of Korean Medical Science
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• 제33권52호
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• pp.337.1-337.14
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• 2018

Background: Mitochondrial heteroplasmy, the co-existence of different mitochondrial polymorphisms within an individual, has various forensic and clinical implications. But there is still no guideline on the application of massively parallel sequencing (MPS) in heteroplasmy detection. We present here some critical issues that should be considered in heteroplasmy studies using MPS. Methods: Among five samples with known innate heteroplasmies, two pairs of mixture were generated for artificial heteroplasmies with target minor allele frequencies (MAFs) ranging from 50% to 1%. Each sample was amplified by two-amplicon method and sequenced by Ion Torrent system. The outcomes of two different analysis tools, Torrent Suite Variant Caller (TVC) and mtDNA-Server (mDS), were compared. Results: All the innate heteroplasmies were detected correctly by both analysis tools. Average MAFs of artificial heteroplasmies correlated well to the target values. The detection rates were almost 90% for high-level heteroplasmies, but decreased for low-level heteroplasmies. TVC generally showed lower detection rates than mDS, which seems to be due to their own computation algorithms which drop out some reference-dominant heteroplasmies. Meanwhile, mDS reported several unintended low-level heteroplasmies which were suggested as nuclear mitochondrial DNA sequences. The average coverage depth of each sample placed on the same chip showed considerable variation. The increase of coverage depth had no effect on the detection rates. Conclusion: In addition to the general accuracy of the MPS application on detecting heteroplasmy, our study indicates that the understanding of the nature of mitochondrial DNA and analysis algorithm would be crucial for appropriate interpretation of MPS results.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7935-7941
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• 2015

The aim of this study was to implement massive parallel sequencing (MPS) technology in clinical genetics testing. We developed and tested an amplicon-based method for resequencing the BRCA1 and BRCA2 genes on an Illumina MiSeq to identify disease-causing mutations in patients with hereditary breast or ovarian cancer (HBOC). The coding regions of BRCA1 and BRCA2 were resequenced in 96 HBOC patient DNA samples obtained from different sample types: peripheral blood leukocytes, whole blood drops dried on paper, and buccal wash epithelia. A total of 16 random DNA samples were characterized using standard Sanger sequencing and applied to optimize the variant calling process and evaluate the accuracy of the MPS-method. The best bioinformatics workflow included the filtration of variants using GATK with the following cut-offs: variant frequency >14%, coverage ($>25{\times}$) and presence in both the forward and reverse reads. The MPS method had 100% sensitivity and 94.4% specificity. Similar accuracy levels were achieved for DNA obtained from the different sample types. The workflow presented herein requires low amounts of DNA samples (170 ng) and is cost-effective due to the elimination of DNA and PCR product normalization steps.

• 분석과학
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• 제32권6호
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• pp.243-251
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• 2019

미세플라스틱이 해양에서 대량으로 발견되어 생태계에 큰 위협이 되고 있다. 국내에서도 우리가 실생활에서 직접 섭취하거나 음식에 많이 사용되는 천일염에서 미세플라스틱이 검출되었다는 보고가 있었다. 미세플라스틱을 분석하기 위하여는 성분, 크기, 모양 등에 대한 정보가 필요하며 이를 위하여 20 ㎛ 크기까지는 FT-IR 현미경이 가장 많이 사용되고 있다. 그러나 최근에는 20 ㎛ 이하의 초 미세 플라스틱 분석이 가능한 라만 현미경법이 함께 많이 연구되고 있다. 본 연구에서는 시판 천일염 10.0 g을 녹인 후 25.4 mm × 25.4 mm 크기의 45 ㎛ mesh 필터로 여과한 후 필터 시료를 각각 FT-IR 현미경과 라만 현미경을 사용하여 미세플라스틱을 분석하였다. FT-IR 현미경의 경우 70 ㎛에서 100 ㎛까지의 3개의 폴리에틸렌(PE)와 170 ㎛의 폴리프로필렌(PP)가 검출되었다. 라만현미경에서는 45 ㎛ 필터를 사용하였음에도 불구하고 필터의 일부에 걸쳐서 여과되지 않고 존재하던 10 ㎛, 30 ㎛의 PE를 포함하여 50 ㎛에서 120 ㎛까지 총 9 개의 PE와 1 개의 40 ㎛ 크기의 폴리스티렌(PS) 1 개가 검출되었다. 검출된 PE 중에는 PE와 Al₂O₃가 함께 결합한 70 ㎛ 미세플라스틱과 원형이 아닌 200 ㎛ × 30 ㎛, 150 ㎛ × 20 ㎛의 비정형 PE도 함께 측정되었다. 미세플라스틱 외에도 총 100 개 이상의 입자들이 측정되었으며 이들의 조성을 보면 5 개의 셀룰로오스, 16 개의 유리류, 35 개의 탄소, 28 개의 미네랄등과 확인이 되지 못한 19 개의 입자들이 측정되었다. 따라서 라만현미경은 적외선현미경에 비하여 20 ㎛ 이하의 미세플라스틱도 측정이 가능하기 때문에 시료의 량도 10배이상 적게 사용할 수 있어 시료 전처리 및 크기에 따른 분석오차를 줄일 수 있다.