• Title/Summary/Keyword: Long term effect

검색결과 3,402건 처리시간 0.031초

Fully Implantable Deep Brain Stimulation System with Wireless Power Transmission for Long-term Use in Rodent Models of Parkinson's Disease

  • Heo, Man Seung;Moon, Hyun Seok;Kim, Hee Chan;Park, Hyung Woo;Lim, Young Hoon;Paek, Sun Ha
    • Journal of Korean Neurosurgical Society
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    • 제57권3호
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    • pp.152-158
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    • 2015
  • Objective : The purpose of this study to develop new deep-brain stimulation system for long-term use in animals, in order to develop a variety of neural prostheses. Methods : Our system has two distinguished features, which are the fully implanted system having wearable wireless power transfer and ability to change the parameter of stimulus parameter. It is useful for obtaining a variety of data from a long-term experiment. Results : To validate our system, we performed pre-clinical test in Parkinson's disease-rat models for 4 weeks. Through the in vivo test, we observed the possibility of not only long-term implantation and stability, but also free movement of animals. We confirmed that the electrical stimulation neither caused any side effect nor damaged the electrodes. Conclusion : We proved possibility of our system to conduct the long-term pre-clinical test in variety of parameter, which is available for development of neural prostheses.

장기현장실습 프로그램의 만족도 영향요인 탐색: K대학 IPP 프로그램을 중심으로 (An exploration of factors affecting the Satisfaction of long-term on-site training: Focusing on IPP of K University)

  • 이지영;이상곤
    • 공학교육연구
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    • 제21권5호
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    • pp.40-53
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    • 2018
  • The purpose of this study was to investigate the factors affecting the satisfaction of the program for the quality improvement of the long-term on-site training operated by the university. The survey questionnaire data of 393 students who participated in the IPP program of K university were used to analyze the data and the results were as follows: First, factors affecting the satisfaction of long-term on-site training were corporation factors and university factors. Specifically, job contents, coaching, job scope, center support were found to have a significant effect in that order. Second, the factors affecting the satisfaction of long-term on-site training were different according to group characteristics(IPP participation types, major types, corporation types). It is necessary to intensively manage the common and important corporation factors, and it is necessary to closely examine each factor derived from group characteristics, and to support and strive at university level according to group characteristics in student counseling and matching.

요양병원 간호사의 임종간호수행 구조모형 (A Structural Equation Model of Terminal Care Performance for Long-term Care Hospital Nurses)

  • 임귀연;최소영
    • 한국보건간호학회지
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    • 제37권2호
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    • pp.275-289
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    • 2023
  • Purpose: This study developed a structural model for explaining and predicting terminal care performance in long-term care hospital nurses. The model was based on the stress integration model of Ivancevich and Matteson(1980) and the results of previous studies. Method: Data was obtained from August to September 2022 from 267 nurses in 13 long-term care hospitals in G-do. Results: Results of model verification for this study, revealed that factors directly affecting the terminal care performance of long-term care hospital nurses were nursing work environment(β=0.43, p<0.001), death anxiety(β=-0.29, p<0.001), and terminal care stress(β=0.22, p=0.003). However, the attitude toward nursing care of dying(β=0.07, p=0.287) had no effect on the terminal care performance. Conclusion: The results of this study, confirmed the necessity of improving an individual's perceived nursing work environment, continuous education related to terminal care to reduce death anxiety, and an interventional approach for enhancing terminal care performance.

환자 및 시설 특성이 장기요양서비스 이용 노인의 자원소모량에 미치는 영향 (The Effects of Patient and Facility Characteristics On the Resource Use by the Elderly in Long-term Care Services)

  • 권순만;김홍수;김선민
    • 보건행정학회지
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    • 제12권1호
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    • pp.21-53
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    • 2002
  • The purpose of this study is to measure the resource use of the elderly in long-term care services and to examine the effects of patient and facility characteristics on their use of resources. The data were collected from 510 old people over sixty years of age, residing in five long-term care hospitals and two skilled nursing homes during the period between December 1, 2000 and February 28, 2001. For a full sample, when the first level of RUG(Resource Use Group)-III categories were employed as the proxy of patient severity, facility characteristics, such as location, size and ownership, have large effects on the resource use measured by service intensity, whereas patient characteristics such as severity have little or no effect. The resource use is significantly high if the facility: (1) is located in rural areas (gun): (2) has mare than 200 beds; (3) is a long-term care hospital; (4) is private; and (5) has a low percentage of medical aid patients. The analysis of the resource use in each RUG-III categories, for which ADL(Ability of Daily Living) were employed as the prosy of patient severity, shows a similar result. The loose relationship between the needs of residents and the resource use seems to be closely associated with the ineffective reimbursement system for providers. The current reimbursement system has no provision for quality improvement and reimburses facilities simply according to their types: fee-for-service for long-term care hospitals, and monthly-flat-rate or full-coverage-national-aid for skilled nursing facilities. It will be necessary to develop a more reasonable reimbursement system that takes patient's severity into account and gives incentives for long-term care providers to offer cost-effective services.

노인요양 시설내 학대경험이 이용 노인의 삶의 만족도에 미치는 영향 (The Effect of Experience of Abuse on Life Satisfaction of the elderly in Long-term Care Facilities)

  • 배진희;정미순
    • 한국콘텐츠학회논문지
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    • 제17권6호
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    • pp.591-599
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    • 2017
  • 노인장기요양보험제도 도입으로 노인요양시설과 요양시설 이용자가 급증하고 있다. 그럼에도 불구하고 노인 요양시설내 학대 발생 현황과 그로 인해 이용노인의 삶에 어떠한 영향을 미치는지에 대한 관심과 연구는 부족한 실정이었다. 이에 본 연구는 2개 지역에 소재한 44개 요양시설 이용노인 278명을 대상으로 자료를 수집하여 분석하였다. 학대경험과 서비스 품질 인식, 서비스 만족도, 삶의 만족도간의 관계를 분석하기 위해 SPSS 20프로그램과 AMOS 18프로그램을 이용해 분석하였다. 분석결과 요양시설 이용 노인의 학대 피해 경험을 확인할 수 있었는데 특히 성학대 피해 경험이 가장 많이 보고되었다. 학대 피해 경험은 이용노인의 서비스품질에 대한 인식, 서비스 만족도, 삶의 만족도에 유의미한 영향을 미치는 것으로 나타났다. 즉 학대를 경험한 노인은 기관의 서비스 품질과 서비스 만족도에 대해 낮게 평가하였고, 삶의 만족도 또한 낮게 나타났다. 학대 경험은 이용 노인의 삶의 만족도에 직접적 영향을 미칠 뿐만 아니라 서비스 만족도를 매개로 간접적으로도 영향을 미치는 것으로 나타났다. 이러한 연구 결과를 바탕으로 노인 요양시설내 노인 학대 예방을 위한 방안을 제시하였다.

Effect of Korean red ginseng extract on liver damage induced by shortterm and long-term ethanol treatment in rats

  • Seo, Su-Jeong;Cho, Jae Youl;Jeong, Yeon Ho;Choi, Yong-Soon
    • Journal of Ginseng Research
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    • 제37권2호
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    • pp.194-200
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    • 2013
  • Korean red ginseng (KRG) is prepared by the process of steaming the roots of Panax ginseng. In this study, the feeding effects of KRG-water extract (KRGE) on ethanol-induced liver damage were elucidated by measuring serum biomarkers in rats. Serum ${\gamma}$-glutamyltranspeptidase (g-GT) activity and the concentration of malondialdehyde (MDA) were significantly increased by short-term and long-term ethanol treatment in rats, whereas the activities of serum glutamate pyruvate transaminase (GPT) and glutamate oxaloacetate transaminase (GOT) did not respond. Pretreatment with KRGE maintained the activity of serum GPT, and the MDA concentration induced by short-term ethanol ingestion remained within the normal range. However, co-feeding of KRGE to rats decreased the concentration of MDA but failed to modulate the serum ${\gamma}$-GT activity induced by long-term ethanol treatment. Our studies suggest that in rats, it appears that KRGE does not sufficiently reverse the physiological response evoked by long-term ethanol ingestion to maintain normal conditions, in view of the serum biomarker ${\gamma}$-GT, regardless of KRGE's favorable antioxidant activity.

서울과 부산에서 관측된 일조 시간 및 강수 강도의 장기 변동 분석 (Analysis of Long-term Variations of Sunshine Duration and Precipitation Intensity Using Surface Meteorological Data Observed in Seoul and Busan in Korea)

  • 이효정;김철희
    • 대기
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    • 제19권3호
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    • pp.243-253
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    • 2009
  • In other to interpret the long-term variations of sunshine duration, cloud lifetime, and precipitation intensity observed in and around Seoul and Busan for the period from 1986 to 2005, aerosol indirect effect was employed and applied. For the identification of long-term trend of aerosol concentration, observed visibility and AOT of AERONET sunphotometer data were also used over the same regions. The result showed that the time series of visibility was decreased and those of AOT increased, especially trends were remarkable in 2000s. In both regions, occurrence frequencies of observed cloudiness (cloud amount ${\leq}6/10$) and strong precipitation (rain rate > $0.5mmhour^{-1}$) have been steadily increased while those of cloudiness (cloud amount > 7/10) and weak precipitation (rain rate ${\leq}0.2mmhour^{-1}$) decreased. These results are corresponding to the trend of both visibility and AERONET data, implying the aerosol indirect effect that makes size of cloud droplet reduce, cloud life-time longer and precipitation efficiency decreased. Our findings demonstrate that, although these phenomena are not highly significant, weather and climate system over Korean urban area have been changed toward longer lifetime of small cloudiness and increasing precipitation intensity as a result of increased aerosol indirect effect.

TV뉴스의 카메라워크와 수용자의 관여도가 뉴스 기억에 미치는 영향 (Effect of TV news camerawork and viewers' involvement on memory of news)

  • 박덕춘
    • 디지털융복합연구
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    • 제11권7호
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    • pp.297-304
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    • 2013
  • 본 연구는 텔레비전 뉴스의 카메라워크와 수용자의 관여도가 뉴스에 대한 장단기 기억에 어떠한 영향을 미치는지 실험을 통해 살펴보았다. 본 연구를 위해 카메라워크의 유무에 따라 2가지 종류의 TV뉴스를 제작하여 관여도를 조작한 2개의 대학생 집단에게 시청하게 하고, 이들의 장단기 기억을 측정, 분석하였다. 분석결과 TV뉴스 영상의 카메라워크는 수용자의 단기기억에는 영향을 미치지 못하지만, 장기기억에는 영향을 미치는 것으로 나타났다. 또한 관여도가 높은 수용자들은 뉴스 내용에 대한 장단기 기억이 높은 것으로 나타났다. 그러나 카메라워크는 주변단서로서 고관여도 수용자보다 저관여도 수용자의 기억에 더 큰 영향을 미칠 것으로 예측한 가설은 지지되지 못하였다.

한국인 우울 장애 환자에서 5-HTTLPR과 항우울제의 장기 치료 반응 (5-HTTLPR and Long-term Effect of Antidepressant Treatment in Korean Depressive Patients)

  • 이화영;함병주;이민수
    • 생물정신의학
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    • 제9권1호
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    • pp.34-41
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    • 2002
  • Background:Since serotonin neurotrasnmission plays an important role in the pathophysiology of depression, the drug that acts on serotonin transporter can be an effective antidepressant. The aim of this study was to investigate the relationship between serotonin transporter polymorphisms(5-HTTLPR) and the long-term effect of the antidepressant treatment. Method:The 175 depressive patients, who met DSM-IV criteria for major depressive disorder or dysthymic disorder were enrolled into three year study. The genotypes of the patients were investigated by polymerase chain reaction of genomic DNA with promoter regions of the serotonin transporter gene. The patients were assessed by the Clinical Global Impression Scale, at the 1st visit, 8th week, 16th week, 1st year, 2nd and 3rd year after the antidepressant treatment. Result:The genotypes of 138 patients were investigated and 128 of them finished this 1st year study and 107 remained in the study after 2-year treatment, and, 97 completed this 3-year study. The therapeutic response of each subset was not different at 8th, 16th week, but the subset with homozygote(l/l) of long variant showed a better antidepressant therapeutic response than heterozygote(l/s). The heterozygote(l/s) showed a better response than the subset with homozygote(s/s) of short variant at 1st, 2nd and 3rd year after the antidepressant treatment in CGI-global improvement score. Conclusion:This result shows that the serotonin transporter polymorphism may be related to the long-term effect of antidepressant treatment and there may be also ethnic difference.

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Long-Term Monitoring of the Barrier Effect of the Wild Boar Fence

  • Lim, Sang Jin;Kwon, Ji Hyun;Namgung, Hun;Park, Joong Yeol;Kim, Eui Kyeong;Park, Yung Chul
    • Journal of Forest and Environmental Science
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    • 제38권2호
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    • pp.128-132
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    • 2022
  • Wild boars (Sus scrofa) not only cause crop damage and human casualties, but also facilitate the spread of many infectious diseases in domestic animals and humans. To determine the efficiency of a fencing system in blocking the movement of wild boars, long-term monitoring was performed in a fenced area in Bukhansan National Park using camera traps. Upon monitoring for a period of 46 months, there was a 72.6% reduction in the number of wild boar appearances in the fence-enclosed area, compared to that in the unenclosed area. For 20 months after the fence installation, the blocking effect of the fence was effective enough to reduce the appearance of wild boars by 92.6% in the fence-enclosed area, compared to that in the unenclosed area. The blocking effect of the fence remained effective for 20 months after its installation, after which its effectiveness decreased. Maintaining a fence for a long time is likely to lead to habitat fragmentation. It can also block the movement of other wild animals, including the endangered species - the long-tailed goral. This study suggests a 20-month retention period for the fences installed to inhibit the movement of wild boars in wide forests such as Gangwon-do in South Korea. To identify how long the blocking effect of the fences lasts, further studies are needed focusing on the length and height of the fence, and the conditions of the ground surface.