• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2012.05a
• /
• pp.722-725
• /
• 2012

In this paper, we design an 8-bit eSuse OTP (one-time programmable) memory based on a $0.35{\mu}m$ BCD process using differential paired eFuse cells which can sense BL data without a reference voltage and also have smaller sensing resistances of programmed eFuse links. The channel widths of a program transistor of the differential eFuse OTP cell are splitted into $45{\mu}m$ and $120{\mu}m$. Also, we implement a sensing margin test circuit with variable pull-up loads in consideration of variations of the programmed eFuse resistances. It is confirmed by measurement results that the designed 8-bit eFuse OTP memory IP gives a better yield when the channel width is $120{\mu}m$.

• CELLMED
• /
• v.10 no.2
• /
• pp.16.1-16.8
• /
• 2020

Standardization of drug deals with confirmation of drug identity and determination of drug quality and purity. Unani herbal formulations are used in traditional medicine for the treatment of various diseases. Cancer is a disease which causes abnormal, uncontrolled growth of body tissue or cells, which tend to proliferate in an uncontrolled way. Spread of cancer from site of origin to other organs of the body is called metastasis. It is a hyper proliferative disorder involving, transformation, dysregulation of apoptosis, invasion and angiogenesis. The present study aimed to standardize a classical Unani formulation (CUF) described as anticancer properties. The CUF has been used for anti-cancerous activity (Dāfi'-i-saraṭān) in human population by Unani physicians for centuries. The standardization parameters carried out for classical Unani formulation are pharmacognostical studies, physicochemical parameters, high-performance thin layer chromatography (HPTLC), microbial load, aflatoxins, and heavy metals revealing specific identities and to evaluate Pharmacopoeial standards. Experiment and the data obtained established the Pharmacopoeial standards for this formulation for identification and quality control purpose. The CUF has been successfully standardized and standard operating procedures (SOPs) for its preparation has been laid down which may serve as a standard reference in future. The standardization data of this formulation may be used as a standard guideline for preparation of the formulation in future.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.30 no.2
• /
• pp.1-11
• /
• 2002

In the present study, a parallel DSCM technique based on a cell-based data structure is developed for the efficient simulation of rarefied gas flows especially od PC clusters. Dynamic load balancing is archieved by decomposing the computational domain into several sub-domains and accounting for the number of particles and the number cells of each domain. Mesh adaptation algorithm is also applied to improve the resolution of the solution and to reduce the grid dependency. It was demonstrated that accurate solutions can be obtained after several levels of mesh adapation starting from a coars initial grid. The method was applied to a two-dimensioanal supersonic leading-edge flow and the axi-symmetric Rothe nozzle flow to validate the efficiency of the present method. It was found that the present method is a very effective tool for the efficient simulation of rarefied gas flow on PC-based parallel machines.

• 한국신재생에너지학회:학술대회논문집
• /
• 2005.06a
• /
• pp.339-344
• /
• 2005

A PEMFC system model for FCEV was constructed and simulated numerically to examine the heat/water flow of the system and air/fuel humidification process for various operation conditions (ambient pressure /temperature/humidity, operating temperature, power load). We modeled PEMFC stack which can generate maximum electricity of about 80 kW. This stack consists of 400 unit cells and each unit cell has $250cm^2$ reacting area. Uniform current density and uniform operating voltage per each cell was assumed. The results show the flow characteristics of heat and water at each component of PEMFC system in macro-scale. The capacity shortage of the radiator occurred when the ambient was hot $(over\;40^{\circ}C)$ and power level was high (over 50 kW). In spite of some heat release by evaporation of water in stack, heat unbalance reached to 20kW approximately in such a severe operating condition. This heat unbalance could be recovered by auxiliary radiators or high speed cooling fan with additional cost. In cold environment, the capacity of radiator exceeded the net heat generation to be released, which may cause a problem to drop the operating temperature of stack. We dealt with this problem by regulating mass flow rate of coolant and radiator fan speed. Finally, water balance was not easily broken when we retrieved condensed and/or unused water.

• Childhood Kidney Diseases
• /
• v.19 no.2
• /
• pp.176-179
• /
• 2015

Rituximab (RTX), a monoclonal antibody against the B-cell marker CD20, is commonly used as a treatment for antibody-mediated diseases or B-lymphocyte-mediated diseases. Destruction of B cells may reverse the disease course in many conditions; however, patients who are treated with RTX cannot respond appropriately to de novo infection due to lack of B lymphocytes. Here, we report one such case. A 7-year-old renal allograft recipient presented with severe anemia due to parvovirus infection after RTX treatment. The patient had focal segmental glomerulosclerosis and had received cadaveric kidney transplantation 6 months previously. She was treated with high-dose steroid for acute rejection and RTX for Epstein Barr Virus infection 3 months previously. At presentation, her hemoglobin level was 5.4 g/dL and leukocyte and platelet counts were normal. She had microcytic normochromic anemia and high viral load of parvovirus B19(70,578 copies/mL). Intravenous immunoglobulin ($200mg/kg{\cdot}d$) treatment controlled the progression of anemia and parvovirus infection. De novo parvovirus infection during the B lymphocyte-depletion period may have precipitated the severe anemia in this case. Close monitoring of infection is required after RTX therapy.

• Magazine of the Korea Concrete Institute
• /
• v.6 no.1
• /
• pp.89-100
• /
• 1994

The current test procedure for transfer length, which determine transfer length by measuring concrete strain, has an actual bond stress state in the prestressed pretensioned member : however, it is difficult to determine the bond properties of maximum bond stress and bond stiffness with this method. It is also difficult for design engineer to understand and select a correct safety criterion from the widely distributed results of such a ransfer test alone. An alternative testing procedure is provided here to determine the bond properties without measuring the concrete strain. In this test the bond stress is measured directly by creating a similar boundary condition within the transfer length in a real beam during the transfer of prestressing force. The prestressing force was released step by step by step from the unloading side. The release of force induces a swelling of the strand at the unloading side of concrete block, bonding force in the block, and a bond slip of the strand toward the other side of the block. Two center-hole load cells are used to record the end loads until the point of general bond slip(maximum bond stress). It is suggested that this test procedure be performed with the ordinary transfer test when determining the transfer length in a prestressed, pretensioned concrete beam.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.31 no.2
• /
• pp.1-9
• /
• 2003

In the present study, a 3-D Parallel DSMC method in developed on unstructured meshes for the efficient simulation of rarefied gas flows. Particle tracing between cells in achieved based on a linear shape function extended to three dimensions. For high parallel efficiency, successive domain decomposition is applied to achieve load balancing between processors by accounting for the number of particles. A particle weighting technique is also adopted to handle flows containing gases of significantly dirrerent number densities in the same flow domain. Application is made for flow past a 3-D delta wing and the result is compared with that from experiment and other calculation. Flow around a rocket payload at 100km altitude is also solved and the effect of plume back flow from the nozzle in studied.

• Journal of Ginseng Research
• /
• v.28 no.4
• /
• pp.173-182
• /
• 2004

We have shown that long-term intake of Korean red ginseng (KRG) delays disease progression in HIV-I infected patients. In the present study to investigate whether this slow progression was associated with protective human leukocyte antigen (HLA) alleles as well as with KRG-intake, we have performed clinical analysis of 31 HIV-1 infected patients who have been living for more than 10 years without any antiretroviral therapy. Average amount of KRG-intake over $130\;{\pm}16$ months was $4,797\;{\pm}4,921\;g$ and the annual decrease in CD4 T cell (AD) was $30\;{\pm}29{\mu}L$. We observed significant correlations among amount of KRG-intake, AD(r=-0.53, P < 0.01), and plasma HIV-1 RNA copy (r=-0.35, P < 0.05), along with a significant correlation between KRG-intake and HLA score AD(r=-0.49, P < 0.01), whereas there was no significant correlation between HLA score and AD or viral load. When the 31 patients were divided into 2 groups based on the amount of KRG-intake, the $AD(14/{\mu}L)$ in the 16 patients who had taken higher amounts of KRG was significantly less than that $(49/{\mu}L)$ in the 15 patients with a little or no KRG-intake (P < 0.01). These data indicate that KRG-intake sig­nificantly slows CD4 T cell depletion in HIV-1 infected patients.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.44 no.1
• /
• pp.28-35
• /
• 2007

In this paper, an ultra low voltage SRAM design method based on dual-boosted cell bias technique is described. For each read/write cycle, the wordline and cell power node of the selected SRAM cells are boosted into two different voltage levels. This enhances SNM(Static Noise Margin) to a sufficient amount without an increase of the cell size, even at sub 1-V supply voltage. It also improves the SRAM circuit speed owing to increase of the cell read-out current. The proposed design technique has been demonstrated through 0.8-V, 32K-byte SRAM macro design in a $0.18-{\mu}m$ CMOS technology. Compared to the conventional cell bias technique, the simulation confirms an 135 % enhancement of the cell SNM and a 31 % faster speed at 0.8-V supply voltage. This prototype chip shows an access time of 23 ns and a power dissipation of $125\;{\mu}W/Hz$.

• Journal of Navigation and Port Research
• /
• v.38 no.2
• /
• pp.97-103
• /
• 2014

In these days, the world has been increasing navy forces such as aircraft carriers and high-tech destroyers etc. and the importance of submarines is being emphasized. Therefore, accurate values of the derivatives in equations of motion are required to control motion of the submarines. Hydrodynamic derivatives were measured by the vertical planar motion mechanism(VPMM) model test. VPMM equipment gave pure heave and pitch motion respectively to the submarine model and the forces and moments were acquired by load cells. As a result, the hydrodynamic derivatives of the submarine are provided through the Fourier analysis of the forces and moments in this paper.