• Journal of Microbiology and Biotechnology
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• 제26권7호
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• pp.1216-1223
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• 2016

The aim of this study was to isolate antioxidant peptides from an enzymatic hydrolysate of Spirulina platensis. A novel antioxidant peptide was obtained by ultrafiltration, gel filtration chromatography, and reverse-phase high-performance liquid chromatography, with the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay used to measure the antioxidant activity, and the sequence was determined to be Pro-Asn-Asn (343.15 Da) by electrospray ionization tandem mass spectrometry. This peptide was synthesized to confirm its antioxidant properties, and it exhibited 81.44 ± 0.43% DPPH scavenging activity at 100 μg/ml, which was similar to that of glutathione (82.63 ± 0.56%). Furthermore, the superoxide anion and hydroxyl free-radical scavenging activities and the SOD activity of the peptide were 47.84 ± 0.49%, 54.01 ± 0.82%, and 12.55 ± 0.75%, respectively, at 10 mg/ml. These results indicate that S. platensis is a good source of antioxidant peptides, and that its hydrolysate may have important applications in the pharmaceutical and food industries.

• International Journal of Fluid Machinery and Systems
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• 제1권1호
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• pp.121-139
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• 2008

For mechanical drive steam turbines, the investigation results of corrosion fatigue phenomena in the transient zone are introduced, including basic phenomena on expansion line and actual design and damage experience. These results were analyzed from the standpoint of stress intensity during the start of cracking. In order to resolve such problems, preventive coating and blade design methods against fouling and corrosive environments are developed. Detailed evaluation test results are given for coating performance using a unique test procedure simulating fouling phenomena and washing conditions. Finally, the results of the successful modification of internals and on-line washing results on site are introduced.

• 디자인학연구
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• 16호
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• pp.149-158
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• 1996

장신구 디자인은 현대인의 생활과 문화, 그리고 관련산업 전반에 걸쳐 큰 영향을 미치고 있으나 현재 우리 나라 대학의 공예디자인 교육에서는 금속 공예의 일부분으로 인식되어 독창성 있는 교육 프로그램을 실시하지 못하고 있다. 대부분의 미술 대학에서 순수 예술성을 추구하는 일품 공예 위주의 장신구 교육을 시행함으로써 장신구 디자인 교육은 산업 생산과 경영 측면을 이해 할 수 없는 비현실적이라는 비판을 받고 있는 것이다. 본 연구에서는 획일적인 대학 장신구 디자인 교육의 문제점 및 개선 방향을 연구하여 장·단기적인 계획안을 제시하였으며, 이를, 토대로 각 대학별 특성을 살린 다양한 장신구 관련 교과과정을 개발, 시행한다면 교육 개방에 대비한 대학 경쟁력 강화와 대학의 산업 기여도 증진 및 관련 전공자들의 사회 활동의 폭을 넓히는 계기가 되리라는 것을 확인하였다.

• 품질경영학회지
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• 제33권2호
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• pp.51-63
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• 2005

The clear and mechanical definition of quality is the key success factor for its wide adoption across various industries and non-profit organizations and its popularity as a managerial goal. However, 'Quality of Life'(QOL) which is a common research subject for the various social science fields seems to require a quite different conceptualization of quality. The paper is a conceptual paper which identifies the compatibility and differences between a traditional quality concept and quality in QOL studies. Also, demonstrating from the social systems perspective how quality is conceptualized in measuring the social dimensions of consumption environmental quality, the paper argues the necessity of a broadened concept regarding quality.

• Fisheries and Aquatic Sciences
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• 제25권7호
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• pp.357-379
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• 2022

Increased fisheries products have raised by-products that are discarded due to low economic value. In addition, marine by-products are still rich in protein and nutritional value that have biological activities and give benefits to human health. Meanwhile, there is raised pressure for sustainability practices in marine industries to reduce waste and minimize the detrimental effect on the environment. Thus, valorization by-products through bioactive peptide mining are crucial. This review focus on various ways to obtain bioactive peptides from marine by-products through protein hydrolysis, for instance chemical hydrolysis (acid and based), biochemical hydrolysis (autolysis and enzymatic hydrolysis), microbial fermentation, and subcritical water hydrolysis. Nevertheless, these processes have benefits and drawbacks which need to be considered. This review also addresses various biological activities that are favorable in pharmaceutical industries, including antioxidant, antihypertensive, anticancer, anti-obesity, and other beneficial bioactivities. In addition, some potential marine resources of Indonesia for the marine biopeptide from their by-product or undesired marine commodities would be addressed as well.

• ALGAE
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• 제25권1호
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• pp.45-56
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• 2010

In this study, we assessed the antioxidant properties of tidal pool microalgae, Halochlorococcum porphyrae and Oltamannsiellopsis unicellularis, from Jeju Island, Korea. Specifically, the antioxidant activity of fractions isolated from 80% methanol extract, and digests produced from five proteases and carbohydrases, were investigated. Almost all the fractions and the 80% methanol extract exhibited higher effects on 1,1-Diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging. The ethyl acetate fraction showed the highest superoxide anion scavenging activity, while both n-hexane and chloroform fractions exhibited higher $H_2O_2$ scavenging activity. Among the enzymatic digests from H. porphyrae and O. unicellularis, all the digests exhibited remarkable DPPH scavenging activities. In nitric oxide inhibition, all the digests recorded significantly higher effects than those of the commercial antioxidants (p < 0.05). Flavozyme and Neutrase digests from H. porphyrae, and Termamyl and Alcalase digests from O. unicellularis, showed significant effects in metal chelating. Lipid peroxidation was significantly inhibited in the ethyl acetate fraction, in the Celluclast and Protamex digests from H. porphyrae, and in the chloroform fraction from O. unicellularis. These findings suggest that the two tidal pool microalgae tested in this study are rich in potential antioxidative compounds, the specific properties of which can be considered for use in the food and pharmaceutical industries.

• 한국해양바이오학회지
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• 제11권1호
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• pp.29-35
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• 2019

In the present study, the alcoholic and enzymatic extracts of Ecklonia maxima were prepared and their antioxidant activities were evaluated via the free radical scavenging activities. The lyophilized seaweed powder was extracted by 70% ethanol and the resultant extract was obtained, named as the alcoholic extract of E. maxima stem (EMSE) obtained. The residue after EMSE preparation was continuously by Celluclast-assistant extraction and then the obtained enzymatic extract was identified as polysaccharides-rich extract of E. maxima stem (EMSP). The results indicated that the extraction yields of EMSE and EMSP were 2.18% and 5.43%, respectively. In addition, the free radical scavenging activities of EMSE and EMSP were determined using an electron spin resonance (ESR) spectrometer. EMSE containing 5.36% of polyphenol and 1.56% of polysaccharide scavenged DPPH and alkyl radicals at the $IC_{50}$ values of 0.48 and 0.63 mg/mL, respectively. EMSP containing 0.33% of polyphenol and 41.58% of polysaccharide showed at the $IC_{50}$ values of 0.33 and 0.55 mg/mL, respectively. These results demonstrate that EMSP containing a high amount of polysaccharides possesses a strong free radical scavenging activity which might be a potential ingredient in pharmacological and cosmeceutical industries.

• ALGAE
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• 제38권4호
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• pp.217-240
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• 2023

Sulfated polysaccharides (SPs) isolated from seaweed have emerged as remarkable bioactive compounds with a wide spectrum of biological activities and have substantial value in the scientific and industrial domains. The current study explores the diverse biological activities of SPs and their relationship with their structures. This aids in an in-depth examination of the multifaceted biological activities of SPs, including anticoagulant, anti-inflammatory, antiviral, antioxidant, and immunomodulatory properties, which underpin their potential health benefits. Furthermore, the current study explores the complicated properties of SPs, with their extraction methodologies and techniques for precise characterization. Elucidation of the commercial significance of SPs derived from brown, red, and green seaweed by highlighting their potential applications has emphasized their importance in human well-being. Further, this review emphasizes the challenges needed to overcome research and industrial innovations for SPs. Collaboration among researchers, industry stakeholders, and regulatory authorities can overcome these challenges and elevate the potential of SPs to revolutionize industries such as pharmaceuticals, cosmeceuticals, food, and biotechnology.

• 한국산학기술학회논문지
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• 제20권7호
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• pp.520-527
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• 2019

본 연구에서는 충북지역 제조업체의 기술 수준과 역량을 진단하여 지역 대학과의 산학협력 효율화에 대한 시사점을 도출하였고 그 결과는 다음과 같다. 첫째 충북지역 산업체들은 중숙련, 고숙련 기업이 75%이며 생산제품의 수명주기는 중 장년기에 접어들은 것으로 조사되었다. 또한 산업체는 마케팅판매기술과 경영 및 관리기술 등의 역량을 과도하게 평가하고 있었다. 따라서 지역 대학들은 산업체의 신산업 육성을 위해 기술이전 및 사업화를 지원하고, 교육과 세미나를 통해 현실 이해와 미래예측 능력을 증진시켜야 할 것이다. 둘째, 충북지역 대학들은 평생교육과정과 같은 일반 교육 프로그램을 우선 제공하여 산업체의 실제적 요구에 부응하지 못했다. 산업체들은 필요인력 배출과 기술교육 등 실무 교육 프로그램을 필요로 했으며, 이외에도 시험, 분석 등의 지식과 인프라 제공, 공동연구 등 기술개발 참여를 기대하고 있었다. 따라서 대학은 수요조사를 통해 맞춤형 협력 프로그램을 준비하고 산업체와 다양한 연결점을 마련해야 할 것이다. 셋째, 충북지역 산업체들의 보유기술은 지역전략산업과 관련성이 매우 낮은 것으로 조사되었다. 이는 산업체와 지자체 간 비전이 공유되지 않은 것으로 대학은 다양한 지역사회 주체들을 조직화할 수 있는 플랫폼 역할을 수행해야 할 것이다.

• 유통과학연구
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• 제11권10호
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• pp.107-116
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• 2013

Purpose - Eggs are nutritionally complete and one of the most popular natural foods. Moreover, the poultry industry is one of the important food industries. However, early industrialization of the poultry industry on its own did not lead to further development compared to other livestock industries. In this study, we investigate what factors influence consumers' behavior and how consumers' understanding of retail business affects their propensity to consume. This study is different from other studies as it analyzes how the brand names of manufacturers and distribution companies affect the purchasing characteristics or actual purchase behavior of consumers in order to suggest how these manufacturers and distribution companies can increase their competitiveness. Research design, data, methodology - This study conducted a survey of 250 randomly selected egg purchasers in discount stores from January to April 2013. Consumers' purchase tendencies were calculated through frequency analysis. This result was then utilized using cluster analysis to draw a conclusion about which purchase tendency influenced consumers buying three different brands of eggs or whether this tendency really affected consumers. As a result, the outcomes of Hypotheses 2 and 3 were not clear so we drew a conclusion with our analysis of Hypothesis 1. Results - While the outcomes of Hypotheses 2 and 3 did not clearly indicate whether purchasing tendencies affected consumers when buying eggs, our analysis of Hypothesis 1 indicated that consumers were affected by the quality of the eggs rather than exterior factors such as the brand name. Thus, we concluded that it is important to promote the excellence of the quality of the eggs. Usually firms buy eggs from farms and repackage them in order to sell them. In this sense, if consumers were aware of this egg production process, and eggs were fairly distributed to retailers, large retail PB businesses would also be able to enhance their competitiveness. Conclusions - The brand, packaging, retail outlet, and other external features influenced the purchase of eggs to a certain degree, while shelf life, grade of the eggs, cleanliness, and other intrinsic characteristics had more influence. In particular, shelf life was the most important factor influencing purchase. Consumers were influenced not only by intrinsic characteristics of the eggs but also by large-scale producers' brands. Consumers relied upon the brand despite reduced competition because they found it difficult to identify shelf life and/or cleanliness. Small businesses and/or large-scale retailers can remain competitive by maintaining the freshness and cleanliness of the eggs. Further studies need to investigate areas in which consumers' cognition of the product is poor and/or the purchase inclination with regard to less developed industries such as eggs. In this study, the greatest problem was that consumers did not consume in accordance with the current situation as consumers have preferred fresh and clean eggs for a long time compared to purchase decisions based on external brands and/or packaging.