• Journal of Digital Convergence
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• v.17 no.3
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• pp.221-226
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• 2019

The characteristic of the beta wave among the EEG waves corresponds to the stress area of human perception. The over-bandwidth of the stress is extracted by analyzing the beta-wave correlation between the low-bandwidth and high-bandwidth. We present a KMeans clustering analysis model for unsupervised machine learning to construct an analytical model for analyzing and extracting the beta-wave correlation. The proposed model classifies the beta wave region into clusters of similar regions and identifies anomalous waveforms in the corresponding clustering category. The abnormal group of waveform clusters and the normal category leaving region are discriminated from the stress risk group. Using this model, it is possible to discriminate the degree of stress of the cognitive state through the EEG waveform, and it is possible to manage and apply the cognitive state of the individual.

• 한국디지털정책학회:학술대회논문집
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• 2005.06a
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• pp.605-615
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• 2005

This paper represent a method of U-Learning based on advanced e-Learning. Ubiquitous computing configuration and advanced Information technology. As we know well, the 21th century is called knowledge based informational society. Many scholar stress that the improved 21th century's educational paradigm be able to success based on advanced educational paradigm. Therefore, we discuss the material for e-Learning fields including with necessity, vision, law, quality authorization etc. Also, we discuss the relational technologies including with meta data, standardization, identification etc. Finally, we propose a method for constructing the U-Learning based on advanced e-Learning and Ubiquitous computing configuration.

• Korean Journal of Medicinal Crop Science
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• v.25 no.6
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• pp.353-360
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• 2017

Background: A critical features of Alzheimer's disease (AD) is cognitive dysfunction, which partly arises from decreased in acetylcholine levels. AD afftected brains are characterized by extensive oxidative stress, which is thought to be primarily induced by the amyloid beta ($A{\beta}$) peptide. In a previous study, Cinnamomum loureiroi tincture inhibited acetylcholinesterase (AchE) activity. That study identified AChE inhibitor in the C. loureiroi extract. Furthermore, the C. loureiroi extract enhanced memory in a trimethyltin (TMT)-induced model of cognitive dysfunction, as assessed via two behavioral tests. Rosa laevigata extract protected against oxidative stress-induced cytotoxicity. Administrating R. laevigata extracts to mice significantly reversed $A{\beta}$-induced learning and memory impairment, as shown in behavioral tests. Methods and Results: We conducted behavioral to examine the synergistic effects of C. loureiroi and R. laevigata extracts in inhibiting AChE and counteracting TMT-induced learning and memory losses. We also performed biochemical assays. The biochemical results showed a relationship between increased oxidative stress and cholinergic neurons damage in TMT-treated mice. Conclusions: A diet containing C. loureiroi and R. laevigata extracts ameliorated learning and memory impairments in the Y-maze and passive avoidance tests, and exerted synergistic inhibitory effect against AChE and lipid peroxidation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.5
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• pp.876-880
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• 2011

Gammakdaejo-Tang (GMT) is a traditional oriental medicinal formula, a mixture of 3 crude drugs, and it has been clinically used for treating mild depressive disorders. The purpose of the study was to examine the effect of Gammakdaejo-Tang (GMT) on repeated stress-induced alterations of learning and memory on a passive avoidance test (PAT) test and also the anxiety-related behavior on the elevated pulse maze (EPM) in ovariectomized female rats. We assessed the changes in the reactivity of the cholinergic system by measuring the immunoreactive neurons of choline acetyltransferase (ChAT) in the hippocampus after behavioral testing. The rats were exposed to the immobilization (IMO) stress for 14 days (2hours/day), and Gammakdaejo-Tang (400 mg/kg, p.o.) was administered 30 min before IMO stress. Treatments with GMT caused significant reversals of the stress-induced deficits in learning and memory on a working memory test, and it also produced an anxiolytic-like effect on the EPM, and increased the ChAT reactivities (p<0.001, respectively). These results suggest that Gammakdaejo-Tang might prove to be an effective antidepressant agent.

• Electrical & Electronic Materials
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• v.10 no.8
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• pp.783-793
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• 1997

A VLSI implementation of a self-learning neural network integrated circuits using a linearity synapse transistor is investigated. The thickness dependence of oxide current density stress current transient current and channel current has been measured in oxides with thicknesses between 41 and 112 $\AA$, which have the channel width $\times$ length 10 $\times$1${\mu}{\textrm}{m}$, 10 $\times$ 0.3${\mu}{\textrm}{m}$ respectively. The transient current will affect data retention in synapse transistors and the stress current is used to estimate to fundamental limitations on oxide thicknesses. The synapse transistor has represented the neural states and the manipulation which gaves unipolar weights. The weight value of synapse transistor was caused by the bias conditions. Excitatory state and inhitory state according to weighted values affected the drain source current.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2000.07a
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• pp.59-62
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• 2000

A VLSI implementation of a self-learning neural network integrated circuits using a linearity synapse transistor is investigated. The thickness dependence of oxide current density, stress current, transient current and channel current has been measured in oxides with thicknesses between 41 and 112 $\AA$, which have the channel width$\times$length 10$\times$1${\mu}{\textrm}{m}$ respectively. The transient current will affect data retention in synapse transistors and the stress current is used to estimate to fundamental limitations on oxide thicknesses. The synapse transistor has represented the neural states and the manipulation which gave unipolar weights. The weight value of synapse transistor was caused by the bias conditions. Excitatory state and inhitory state according to weighted values affected the drain source current.

• Korean Journal of Occupational Health Nursing
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• v.22 no.1
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• pp.57-65
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• 2013

Purpose: The purpose of this study was to evaluate the factors that affected self efficacy, social support and learning achievement in the web-based learning of graduate school students. Methods: The data were collected from 79 nurses in a web-based learning. A self-reported questionnaire was used to assess the level of self-efficacy, social support and learning achievement. Results: The learning achievement was significantly improved to 4.05 points after web-based learning compared to 2.69 points before web-based learning, and all other items were also improved. Self-efficacy was improved to 3.91 points from 3.66 points after web-based learning and so was social support to 4.18 points from 3.94 points. Fatigue and stress among health behavior characteristics were significantly decreased after web-based learning. Conclusion: This study shows that the web-based learning improved self-efficacy and social support of the students. And self-efficacy was an important factor in learning achievement. It is necessary to develop a strategy to improve self-efficacy as well as to manage social support for increasing interactions among the nurses in a web-based learning.

• Journal of Oriental Neuropsychiatry
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• v.18 no.1
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• pp.1-14
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• 2007

Objective : The purpose of this study was to investigate the protective effects of Cheongsimondam-tang(COT) on the animal model of depression induced immobilization stress. Method 1) Male rats were used for this experiment. The subject were divided into 4 groups(1. normal 2. saline solution administered during immobilization stress treatment 3. COT of 100mg/kg administered 4. COT of 400mg/kg administered). 2) Immobilization stress was treated for 1 hours on day. During 2 days of immobilization stress treatment, they were executed forced swimming test, passive avoidance test, elevated plus maze test. Corticosterone in blood were measured Results 1) In EPM test, stress group showed significantly increased anxiety, COT groups showed significantly decreased anxiety. 2) In forced swimming test, COT groups did not show significantly decreased immobilization. 3) In passive avoidance test, stress group showed significantly decreased learning execution, COT groups showed significantly increased learning execution. 4) Stress group showed significantly increase in serum level of corticosterone, COT of 400mg/kg group showed significantly decreased serum level of corticosterone. Conclusion : These results suggest that Cheongsimondam-tang(COT) is effective in the treatment of depression.

• Journal of Korean Academy of Nursing
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• v.17 no.2
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• pp.153-161
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• 1987

This descriptive-correlational study was conducted to recognize the relational between the Perceived social support and stress in pregnant women. The subject were comprised of 154 patients who were at 24 weeks over, and data were collected by way of questionnairs at K-university hospital in Seoul during 23 days (November 21, 1986 to December 13, 1986). The result of this study may be summerized as follows. 1) The degrees of the support from situation perceived by pregnant women were: the minimal 20 feints, the maximal 61 points and the mean 40.42 feints. 2) The degrees of stress perceived by pregnant women were: the minimal 32 points, the maximal 109 points and the mean 65.49 points. 3) The results of hypotheses were: the first hypothesis was not supported that the higher the degree of social support from situation perceived by pregnant women, the lower that of stress(r= -0.01129, p=0.8895) the second was supported that the higher the degree if support perceived indirectly by pregnant women, the lower that of stress(r= -0.23832, p=0.0029). the third was supported that the higher the degree of support perceived directly by pregnant women, the lower that of stress. (r= -0.36019, p=0.0001) 4) The fourth shows that in the relationships between the characteristics of socio-popualtion and obstetrics and the degree of social support, there was significant difference; i) the support from situation differs in learning (t= -2.178, p<.05), and satisfaction of marriage (F=5.06, p<.01) ii) the support perceived indirectly differs in learning (t= -3.065, p<.01), month of pregnant(F= 2.78, p <.05), satisfaction of marriage (F=20.08, p<.001) and forms of family (t=2.11, p<.05) iii) the support perceived directly differs in satisfaction of marriage (F=21.00, p <.001) and forms of family (t=2.11, p<.05) 5) the fifth shows that in the relationship between the characteristics of sociopopulation and obstetrics and stress, the degree of satisfaction of marriage only shows the significant statistical difference(F= 0.40, p<.01) 6) The sixth shows that the factor affecting the stress of pregnant women was the support perceived directly and its explanatory power was 12.9%.

• Journal of Oriental Neuropsychiatry
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• v.18 no.2
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• pp.45-55
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• 2007

Objective : The purpose of this study was to investigate the protective effects of Radix Curcumae on the animal model of depression induced immobilization stress. Method : 1) Male rats were used for this experiment. The subject were divided into 4 groups(1. normal 2. saline solution administered during immobilization stress treatment 3. Radix Curcumae of l00mg/kg administered 4. Radix Curcumae of 400mg/kg administered). 2) Immobilization stress was treated for 1 hours on day. During 2 days of immobilization stress treatment, they were executed forced swimming test, passive avoidance test, elevated plus maze test. Corticosterone in blood were measured. Results : 1) In EPM test, stress group showed significantly increased anxiety, Radix Curcumae of 400mg/kg group showed significantly decreased anxiety. 2) In forced swimming test, Radix Curcumae of 400mg/kg group showed significantly decreased immobilization. 3) In passive avoidance test, stress group showed significantly decreased learning execution, Radix Curcumae groups showed significantly increased learning execution. 4) Stress group showed significantly increase in serum level of corticosterone, Radix Curcumae of 400mg/kg group showed significantly decreased serum level of corticosterone. Conclusion : These results suggest that Radix Curcumae is effective in the treatment of depression.