• 제목/요약/키워드: Late response

검색결과 477건 처리시간 0.028초

조직접착제인 Histoacryl을 피하조직에 적용하였을 때의 조직학적 소견에 대한 연구 ("Histologic Examination of Histoacryl When Used in a Subcutaneous Sites.";An Experimental Study)

  • 신동명;김종여;임성빈;정진형
    • Journal of Periodontal and Implant Science
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    • 제29권4호
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    • pp.913-928
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    • 1999
  • Since their discovery in 1949, cyanoacrylates interest many people as possibly being the ideal "Tissue glue". Several different forms of these compounds have been developed in attempt to reduce or eliminate tissue toxicity. Butyl-2-cyanoacrylate(Histoacryl) appears to be the most ideal material as it induces low tissue reactivity & toxicity. In this study, the histotoxic response of histoacryl, when used in a subcutaneous site was compared to a controls which was conventionally sutured. This response was greater than the control that showed no inflammation. However, these findings may not corre-late in actual clinical settings, because most patients tolerate mild degrees of infla-mmation well. Majority of the studies evaluating the histotoxicity of histoacryl have been per-formed when applied superficially & not below the skin surface. This is why further studies are required to evaluate the his-totoxicity of histoacryl when used in a sub-cutaneous site or mucosa.

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유해화학물질 특성정보 데이터베이스 구축 연구 (A Study on Development of Database for the Characteristics of Hazardous Chemicals)

  • 한종엽;송기섭;강성현
    • 정보관리연구
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    • 제28권2호
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    • pp.1-19
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    • 1997
  • 본 연구의 목적은 효율적인 해양개발과 이용 및 해양오염방지를 위해서 해양환경보존과 해양오염 방지에 대한 정보를 이용자가 정확하고 쉽게 접근할 수 있도록 하기 위함이며, 날로 증가추세에 있는 유해화학물질 사고의 피해를 최소화하기 위하여 유해화학물질의 특성과 사고발생시 방재 대책 등을 수록한 유해화학물질 특성정보 1,000종을 데이터베이스화하여 연구전산망과 상용망을 통하여 제공하고 있다.

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신체이미지.신체왜곡 및 자아존중감이 의복행동에 미치는 영향 -태도적.지각적 신체이미지 측정을 중심으로- (The Effects of the Body Image.Body Distortion and the Self-esteem on the Clothing Behaviors)

  • 송경자;김재숙
    • 복식문화연구
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    • 제7권5호
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    • pp.68-79
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    • 1999
  • The purposes of the study, based on the social comparison theory, were 1) to examine the body image and the body distortion of the late adolescent through the attitudinal and perceptual measurement of the body image and to examine the self-esteem, 2) to examine the difference of the clothing behaviors depending on the level of the body image, the body distortion and the self-esteem, 3) to examine the difference in the clothing behavior, the body image and the self-esteem according to sex. The sampling method was a convenient sampling and the subjects were 137 undergraduate students in Chungnam national University. The results of this study were as follows : The results of analysing the factors to the response of attitudinal body image emerged three factors (appearance interest, weight concern, and body satisfaction). The results of analysing the response of the clothing behavior showed four factors (fashion interest, psychological dependence of clothing, conformity to clothing, and exhibitionism of clothing). The positive group to the body image showed more interest in the fashion and had the tendency of depending on the clothing psychologically, and also showed that the group revealed much exhibitive attitude by using the clothing. The group of perceiving the face rather correctly tends to do the conformity behaviors, but the group distorting the shoulder width wider than tends to reveal more conformity behaviors. The group with the higher self-esteem had little interested in the fashion and also did the conformity behaviors slightly.

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Relationship between Olfactory Preferences and Olfactory Event-Related Potentials

  • Lee, Gil-Hyun;Yoon, Hae-Gyung;Kim, Young-Sam;Hyun, Kyung-Yae
    • 대한의생명과학회지
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    • 제26권1호
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    • pp.14-21
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    • 2020
  • Quantitative evaluation of the sense of smell is done by the olfactory event-related potential (OERP) test. OERP consists of N1, P1, N2, P2, and P3, of which N1 and P1 latency are known to be affected by the concentration of odor stimuli associated with the pre-sensory phase and P2 and P3 are the stages at which odors are perceived and are known to change by subjective evaluation of the stimulus. The purpose of this study was to clarify the correlation between the expression of OERP and the subjective evaluation of the object on the fragrance stimulus using various fragrances. Therefore, the study examined the relative waveform power ratio, preference for each scent stimulus, and finally the amplitude and latency change of the components of OERP, N1 and P2. In contrast, it was found that the late P2 response waveform was an effective aroma stimulus recognition waveform in OERP compared to the initial response waveforms.

Effects of sleep deprivation on coronary heart disease

  • Wei, Ran;Duan, Xiaoye;Guo, Lixin
    • The Korean Journal of Physiology and Pharmacology
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    • 제26권5호
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    • pp.297-305
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    • 2022
  • The presence of artificial light enables humans to be active 24 h a day. Many people across the globe live in a social culture that encourages staying up late to meet the demands of various activities, such as work and school. Sleep deprivation (SD) is a severe health problem in modern society. Meanwhile, as with cardiometabolic disease, there was an obvious tendency that coronary heart disease (CHD) to become a global epidemic chronic disease. Specifically, SD can significantly increase the morbidity and mortality of CHD. However, the underlying mechanisms responsible for the effects of SD on CHD are multilayered and complex. Inflammatory response, lipid metabolism, oxidative stress, and endothelial function all contribute to cardiovascular lesions. In this review, the effects of SD on CHD development are summarized, and SD-related pathogenesis of coronary artery lesions is discussed. In general, early assessment of SD played a vital role in preventing the harmful consequences of CHD.

혹명나방 개체군의 수원지역 발생 패턴 및 몇가지 약제에 대한 반응 (The Occurrence of Rice Leaf-folder, Cnaphalocrocis medinalis (Lepidoptera : Crambidae) in Suwon and its Responses to Insecticides)

  • 박홍현;조점래;박창규;김광호;고현관;이상계
    • 한국응용곤충학회지
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    • 제49권3호
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    • pp.219-226
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    • 2010
  • 연구는 2004년부터 2007년까지 수원지역에서 혹명나방 발생과 피해 특성들 및 우리나라와 베트남에서 채집한 개체군들이 몇 가지 약제에 대한 반응을 조사하였다. 포장에서 채집한 유충들의 발육단계는 본 연구의 실내사육충을 대상으로 측정한 두폭과 체장자료를 통해 구분이 가능하였다. 2004년부터 2007년까지 벼 포장에서 조사된 혹명나방은 발생이 많거나 적은 해로 패턴이 분명하게 구분되었다. 발생이 적은 해(2004년 및 2006년)에는 성충이 한 번의 발생 최성기(8월 하순)를 가졌고, 7월 하순의 피해주율이 10% 미만이었으며, 9월 동안에 피해엽률이 2% 수준이었다. 하지만 발생이 많은 해(2005년 및 2007년)에는 두 번의 성충 발생 최성기(8월 초순과 9월 중순)를 가졌고, 피해주율도 7월 하순에 약 30%에 달하였으며, 9월동안에 피해엽률이 15~30%로 경제적 피해수준을 넘었다. 특히 7월 하순과 8월 상순에 조사된 성충 밀도나 피해주율의 크기는 9월에 발생하는 피해규모와 밀접하게 정의 상관이 있었다. 따라서 본 연구결과로 볼 때 7월 하순과 8월 상순에 혹명나방 성충의 발생 및 벼 피해에 관한 예찰정보는 벼 생육후기의 피해예측 및 방제적기 선정에 활용할 수 있을 것으로 여겨진다. 또한 우리나라와 베트남에서 채집한 혹명나방에 대한 약제반응은 두 지역 채집계통에서 모두 IGR계인 tebufenozide, methoxyfenozide나 유기인계인 chlorpyrifos-methyl, pyridaphenthion에는 매우 높은 감수성을 보였으나, 칼탑계인 cartap에는 약제 감수성 정도가 다소 낮았다.

보리 파종기에 따른 유효분벽의 양상과 수량 (Effective Tillering Pattern and Grain Yield on Different Seeding Dates in Barley)

  • 신만균
    • 한국작물학회지
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    • 제40권4호
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    • pp.460-472
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    • 1995
  • 보리의 안전생산기술 체계개선을 위하여 파종기의 조만에 따른 분엽별 생태적인 변화, 유효경 비율, 분엽경별 수량 구성요소와 기여도에 관하여 검토한 바 다음과 같은 결과를 얻었다. 1. 간장은 파종기 간에 큰 차이가 없었으나 분엽차위별 차이는 있었고 주관엽수는 조파구 13.2, 적파구 12.5, 만파구 11. 1매로 조파나 적파구는 만파구보다 1.4~2.1매가 많았다. 2. 유효경발생율은 주간을 제외하고는 조파구 > 적파구 > 만파구의 순으로 파종기가 빠를수록 2, 3차분엽에서 높았다. 유효경 발생율이 100%인 엽자로는 1차분엽중 조파구 1, 2, 적파구와 만파구는 1이었으며 어느 분엽절위에서나 동일모경의 동차위분엽은 자엽소 및 전엽분벽보다 다음 절에서 발생한 분벽, 동지분벽중에는 11, 동신분벽중에는 주간엽위의 하위절분벽이 강대경으로 유효경율이 높았다. 3. 주당 유효경수는 조파구 > 적파구 > 만파구의 순위이나 유효수수는 조파보다 적파구가 많았다. 4. 1수위수는 분벽의 발생시기가 빠른 주간 기부의 저위, 저차위분벽에서 많았고 입수도 유효경발생율과 같이 자엽소나 전엽분벽보다 상위1절의 분벽, 동지분벽중 11, 동신분벽중 주간절위가 저위의 저차위분벽이 강세를 보였다. 5. 포괄적인 유효수의 간입중은 파종기가 빠를수록 무거웠으나 동신엽, 동신분벽간의 간입중 차이는 일양성이 없었다. 6. 1종 자실중도 자엽소 및 전엽분벽보다 다음 상위1절의 분벽경에서 무거웠고 동지분벽중에는 11이 최대이었으며 동신분벽중에는 주간절위에서 저위, 저차분벽이 고위, 고차분벽보다 우세하였다. 7. 분벽의 수량기여도 상위10위까지의 벽자에 있어 전체평균기여도는 1, 2, 0, 11, 3, C, 21, C1, 12, 1P의 순이었으나 파종기의 이동에 따라 다소의 순위의 차가 있었다. 분벽경의 자실중은 $\ulcorner$전생우세$\lrcorner$의 대원칙하에서 다소의 차이를 보였으나 자엽소 및 전엽분벽보다 다음 상위1절의 분벽 즉 $\ulcorner$후생우세$\lrcorner$의 현상을 보여 이른바 가령현상을 나타냈다.

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고등학생의 영양 관련 문제점 분석 및 영양 교육 프로그램 개발 ( I ) - 영양교육 목표 설정을 위한 식생활 문제점 분석 - (Problems Analysis Related to Nutrition and the Development of Nutrition Education Programs for High School Students( I ) - A Study Centered on Analyzing Problems of Dietary Life for Nutrition Education Goal Setting -)

  • 이은주;소혜경;최봉순
    • 동아시아식생활학회지
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    • 제17권3호
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    • pp.338-350
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    • 2007
  • The objectives of this study were to analyze nutrition-related problems and to develop the nutrition education programs for high school students A survey was conducted with 500 students in the second grade level at high schools in Daegu who differed in socio-economic characteristics. In addition, body composition analysis was accomplished by the Inbody 3.0. The developed questionnaires were distributed and 481 questionnaires were collected with a 96.2% of response rate. Statistical data analysis was completed using SPSS WIN(ver.12.0) for descriptive analysis, reliability analysis, factor analysis, t-tests and $X^2$-tests. We first analyzed students' problems related to nutrition and environmental factors. In a question addressing skipping breakfast, only 11.5% answered they "do not eat" breakfast. In regards to BMI, the male students' degree of obesity was higher. Second, we analyzed living environments, which greatly influence dietary behavior. For the snacks-related categories, most of the students liked bread, cake and other snacks. When they chose the snacks, they mainly considered taste. There were significant difference among the males and females(p<.01) in terms of snacks intake habits, where 43.1 % of the males answered they snack "occasionally" and 43.4% of the females answered they snack "according to how they feel". In the case of beverages, the males consumed significantly more(p<.001). Based on their regional groups, the area A group preferred milk and milk products, and the area B group preferred soft drinks. As for the time of beverage intake, 77.6% of the females answered "with snacks", which was significantly higher than 61.4% of the males(p<.001), 12.2% of the males drank beverages after exercise. For late snacking, 68.0% of the male students and 71.1 % of the female students consumed late snacks. Most of them preferred bread, cake and other snacks. The reasons for taking a late snack were "when I feel hungry" by 61.8% of the males which was higher than the females(p<.001), 23.6% of the females consumed late snacks "impulsively". Ideally, in order to improve the food habits of high school students effective and practical nutrition education programs that consider gender and regional school group, should be carried out.

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The effect of nutrition and body condition of triplet-bearing ewes during late pregnancy on the behaviour of ewes and lambs

  • Gronqvist, Gabriella V.;Corner-Thomas, Rene A.;Kenyon, Paul R.;Stafford, Kevin J.;Morris, Stephen T.;Hickson, Rebecca E.
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권12호
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    • pp.1991-2000
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    • 2018
  • Objective: Triplet-born lambs are less likely to survive to weaning than twin-born or single-born lambs. Appropriate ewe-lamb bonding behaviours and lamb vigour behaviours are necessary for survival of lambs. The aim of this experiment was to determine whether maternal nutrition during late pregnancy influenced behaviour of the ewe and her lambs soon after birth, and to determine whether mid-pregnancy body condition score (BCS) influenced any behavioural response. Methods: The experiments included ewes that were in BCS 2.0, 2.5, or 3.0 in mid-pregnancy and were fed either ad libitum or to pregnancy-maintenance requirements in late-pregnancy (day 115 until 136 in experiment one, and day 128 until 141 in experiment two). The time taken for lambs to stand, contact dam, suck from dam and follow dam was recorded three to 18 h after birth. The number of high- and low-pitched bleats emitted by the ewe and lambs was recorded, along with maternal behaviour score (MBS) of the ewe. Lambs in experiment two underwent a maternal-recognition test at 12 or 24 h. Results: There were significant effects of feeding treatment on bleating behaviour of ewes and lambs, but these were inconsistent among BCS groups and between experiments. Lamb vigour behaviours were not affected by feeding treatment. In experiment one, there was no effect of feeding treatment or BCS on MBS, but in experiment two, ewes in BCS3 in mid-pregnancy had greater MBS than ewes in BCS2 in mid-pregnancy (MBS 3.1/5 vs MBS 2.1/5; p<0.05). Conclusion: Given there were no repeatable effects on behaviour of ewes and lambs, ad libitum feeding rather than feeding for pregnancy-maintenance requirements cannot be used to improve behaviours soon after birth of triplet-bearing ewes in BCS 2-3 and their lambs in extensive pastoral conditions.

반지련 약침 추출물의 RBL-2H3 세포 탈과립과 염증매개물질 분비 억제 효과 (Effect of Scutellaria barbata Pharmacopuncture Extract on Degranulation and Inflammatory Mediator Release in RBL-2H3 Cells)

  • 권혁상;송춘호
    • Korean Journal of Acupuncture
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    • 제29권3호
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    • pp.406-420
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    • 2012
  • Objectives : Scutellaria barbata has been widely used in oriental medicine used for treatment of acute and chronic inflammatory diseases. In this study, to investigate the protective effect of Scutellaria barbata on type I allergic response, we determined whether Scutellaria barbata inhibits early or late allergic responses. Methods : To assess the effect of Scutellaria barbata Pharmacopuncture Extract(SB) in RBL-2H3 cells, we investigated the levels of the markers of degranulation such as ${\beta}$-hexosaminidase and histamine, inflammatory mediator such as IL-4, TNF-${\alpha}$, PGE2 and cysLT, and mRNA expression of cytokines and enzymes. In addition, we determined the levels of intracellular ROS by DCFH-DA assay and the free radical scavenging activity by DPPH method. Results : We found that SB suppressed the release of ${\beta}$-hexosaminidase and histamine and the production of IL-4, TNF-${\alpha}$, PGE2 and cysLT in RBL-2H3 by the antigen stimulation. SB also significantly inhibited the enzyme mRNA expressions, such as HDC2, COX-1, COX-2, 5-LOX and iNOS2, along with reduced cytokine mRNA expressions, such as IL-$1{\beta}$, IL-2, IL-3, IL-4, IL-5, IL-6, IL-13, TNF-${\alpha}$ and GM-CSF in RBL-2H3. In addition, SB suppressed the levels of intracellular ROS. Conclusions : Our results indicate that SB protects against type I allergic response and exert an anti-inflammatory effect through the inhibition of degranulation, inflammatory mediator release and mRNA expression of cytokines and enzymes.