Journal of Periodontal and Implant Science
- Volume 29 Issue 4
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- Pages.913-928
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- 1999
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
"Histologic Examination of Histoacryl When Used in a Subcutaneous Sites.";An Experimental Study
조직접착제인 Histoacryl을 피하조직에 적용하였을 때의 조직학적 소견에 대한 연구
- Shin, Dong-Moung (Department of Periodontology College of Dentistry Dan-Kook University) ;
- Kim, Jong-Yoo (Department of Periodontology College of Dentistry Dan-Kook University) ;
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Lim, Sung-Bin
(Department of Periodontology College of Dentistry Dan-Kook University) ;
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Chung, Chin-Hyung
(Department of Periodontology College of Dentistry Dan-Kook University)
- 신동명 (단국대학교 치과대학 치주과학교실) ;
- 김종여 (단국대학교 치과대학 치주과학교실) ;
-
임성빈
(단국대학교 치과대학 치주과학교실) ;
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정진형
(단국대학교 치과대학 치주과학교실)
- Published : 1999.12.31
Abstract
Since their discovery in 1949, cyanoacrylates interest many people as possibly being the ideal "Tissue glue". Several different forms of these compounds have been developed in attempt to reduce or eliminate tissue toxicity. Butyl-2-cyanoacrylate(Histoacryl) appears to be the most ideal material as it induces low tissue reactivity & toxicity. In this study, the histotoxic response of histoacryl, when used in a subcutaneous site was compared to a controls which was conventionally sutured. This response was greater than the control that showed no inflammation. However, these findings may not corre-late in actual clinical settings, because most patients tolerate mild degrees of infla-mmation well. Majority of the studies evaluating the histotoxicity of histoacryl have been per-formed when applied superficially & not below the skin surface. This is why further studies are required to evaluate the his-totoxicity of histoacryl when used in a sub-cutaneous site or mucosa.
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