• Nano
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• 제13권12호
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• pp.1850140.1-1850140.9
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• 2018

An electrochemical sensor ($Cu^{2+}$-IIPs/GCE) was developed for detection of $Cu^{2+}$ in water. $Cu^{2+}$-IIPs/GCE was prepared by dispersing $Cu^{2+}$ imprinted polymers ($Cu^{2+}$-IIPs) on a preprocessed glassy carbon electrode. $Cu^{2+}$-IIPs were synthesized on the surface of modified carbon spheres by ion imprinting technology. The electrochemical performance of $Cu^{2+}$-IIPs/GCE was evaluated by differential pulse voltammetry method. The response of $Cu^{2+}$-IIPs/GCE to $Cu^{2+}$ was linear in $1.0{\times}10^{-5}mol/L$ to $1.0{\times}10^{-3}mol/L$. The detection limit was $5.99{\times}10^{-6}mol/L$ (S=N = 3). The current response value of $Cu^{2+}$-IIPs/GCE was 2.14 times that of the nonimprinted electrode. These results suggest that $Cu^{2+}$-IIPs/GCE can detect the concentration of $Cu^{2+}$ in water, providing a new way for heavy metal ions adsorption and testing.

• BMB Reports
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• 제52권6호
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• pp.379-384
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• 2019

Epithelial-mesenchymal transition (EMT) is widely-considered to be a modulating factor of anoikis and cancer metastasis. We found that, in MDA-MB-231 cells, TP53I11 (tumor protein P53 inducible protein 11) suppressed EMT and migration in vitro, and inhibited metastasis in vivo. Our findings showed that hypoxic treatment upregulated the expression of $HIF1{\alpha}$, but reduced TP53I11 protein levels and TP53I11 overexpression reduced $HIF1{\alpha}$ expression under normal culture and hypoxicconditions, and in xenografts of MDA-MB-231 cells. Considering $HIF1{\alpha}$ is a master regulator of the hypoxic response and that hypoxia is a crucial trigger of cancer metastasis, our study suggests that TP53I11 may suppress EMT and metastasis by reducing $HIF1{\alpha}$ protein levels in breast cancer cells.

• 한국국방경영분석학회지
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• 제35권3호
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• pp.61-79
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• 2009

국방 복합체계(system of systems: SoS, Family of Systems: FoS)의 상호운용성 확보가 정보우위를 제공하며, 정보우위가 전장의 우위를 결정짓는 중요한 요소 중의 하나로 인식되고 있다. 본 연구는 국방 복합체계의 상호운용성 향상을 위해 국방 KIP(Key Interface Profile) 프로세스를 제안한다. 국방 KIP 프로세스는 아키텍처 분석을 통해 핵심 인터페이스를 식별하고, 식별된 핵심 인터페이스 정보를 바탕으로 핵심 인터페이스 프로파일을 개발한다. 개발된 핵심 인터페이스 프로파일은 복합체계의 상호운용성을 관리하기 위해 사용 될 수 있다. 제안 프로세스의 효용성과 실용성을 확인하기 위해 대화력전 수행체계(전구급 타격절차)에 국방 KIP 프로세스를 적용하고, 도출된 시사점을 제시한다.

• Bulletin of the Korean Chemical Society
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• 제29권12호
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• pp.2368-2372
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• 2008

• 한국실내디자인학회논문집
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• 제30호
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• pp.86-91
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• 2002

HCI (Human Computer Interface)is important key of software design. Effectiveness and productivity of CAD software is creation is not study actively in architectural part. The results of this study \circled1 HCI of architectural modeling is demanded effective design of keypad and short key. \circled2 It is require that system reactions to be united in one interface in order to hold in check confusion of the information. \circled3 Intelligent interface for continuous update of 3D information is required.

• Nuclear Engineering and Technology
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• 제52권6호
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• pp.1172-1179
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• 2020

As a Lagrangian particle method, Moving Particle Semi-implicit (MPS) method has great capability to capture interface/surface. In recent years, the multiphase flow simulation using MPS method has become one of the important directions of its developments. In this study, some key methods for multiphase flow have been introduced. The interface tension model in multiphase flow is modified to maintain the smooth of the interface and suitable for the three-phase flow. The mass transfer at immiscible liquid interface entrained by single bubble which could occur in Molten Core-Concrete Interaction (MCCI) has been investigated using this particle method. With the increase of bubble size, the height of entrainment column also increases, but the time of film rupture is slightly different. With the increase of density ratio between the two liquids, the height of entrained column decreases significantly due to the decreasing buoyancy of the denser liquid in the lighter liquid. In addition, the larger the interface tension coefficient is, the more rapidly the entrained denser liquid falls. This study validates that the MPS method has shown great performance for multiphase flow simulation. Besides, the influence of physical parameters on the mass transfer at immiscible interface has also been investigated in this study.

• Geomechanics and Engineering
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• 제24권1호
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• pp.81-89
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• 2021

Uniaxial compression tests were conducted on sandstone-CGFB composite samples with different interface angles, and their strength, acoustic emission (AE), and failure characteristics were investigated. Three macro-failure patterns were identified: the splitting failure accompanied by local spalling failure in CGFB (Type-I), the mixed failure with small sliding failure along with the interface and Type-I failure (Type-II), and the sliding failure along with the interface (Type-III). With an increase of interface angle β measured horizontally, the macro-failure pattern changed from Type-I to Type-II, and then to Type-III, and the uniaxial compressive strength and elastic modulus generally decreased. Due to the small sliding failure along with the interface in the composite sample with β of 45°, AE events underwent fluctuations in peak values at the later post-peak failure stage. The composite samples with β of 60° occurred Type-III failure before the completion of initial compaction stage, and the post-peak stress-time curve initially exhibited a slow decrease, followed by a steep linear drop with peaks in AE events.

• Journal of Advanced Research in Ocean Engineering
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• 제1권1호
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• pp.36-43
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• 2015

Since the crack generation and its propagation caused by welding defects is one of the main hull damage patterns, the simulation of crack propagation process has an important significance for ship safety. Based on interface element method, a finite element model to simulate crack propagation is studied in the paper. A Lennard-Jones type potential function is employed to define potential energy of the interface element. Tensile tests of steel flat plates with initial central crack are carried out. Surface energy density and spring critical stress that are suitable for the simulation of crack propagation are determined by comparing numerical calculation and tests results. Based on a large number of simulation results, the curve of simulation correction parameter plotted against the crack length is calculated.

• Geomechanics and Engineering
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• 제11권3호
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• pp.361-372
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• 2016

The soil-concrete interface shear strength, although has been extensively studied, is still difficult to predict as a result of the dependence on many factors such as normal stresses, surface roughness, particle sizes, moisture contents, dilation angles of soils, etc. In this study, a well-known rigorous statistical learning approach, namely the least squares support vector machine (LS-SVM) realized in a ubiquitous spreadsheet platform is firstly used in estimating the soil-structure interface shear strength. Instead of studying the complicated mechanism, LS-SVM enables to explore the possible link between the fundamental factors and the interface shear strengths, via a sophisticated statistic approach. As a preliminary investigation, the authors study the expansive soils that are found extensively in most countries. To reduce the complexity, three major influential factors, e.g., initial moisture contents, initial dry densities and normal stresses of soils are taken into account in developing the LS-SVM models for the soil-concrete interface shear strengths. The predicted results by LS-SVM show reasonably good agreement with experimental data from direct shear tests.

• Bulletin of the Korean Chemical Society
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• 제31권9호
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• pp.2547-2552
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• 2010

CdS nano-particulate films were prepared at the air/water interface under Langmuir monolayers of arachidic acid (AA) via interfacial reaction between $Cd^{2+}$ ions in the subphase and $H_2S$ molecules in the gaseous phase. The films were made up of fine CdS nanoparticles with hexagonal Wurtzite crystal structure after reaction. It was revealed that the formation of CdS nano-particulate films depends largely on the experimental conditions. When the films were ripened at room temperature or an increased temperature ($60^{\circ}C$) for one day, numerous holes were appeared due to the dissolution of smaller nanoparticles and the growth of bigger nanoparticles with an improved crystallinity. When the films were ripened further, CdS rodlike nanoparticles with cubic zinc blende crystal structure appeared due to the re-nucleation and growth of CdS nanoparticles at the stacking faults and defect structures of the hexagonal CdS grains. These structures were characterized by transmission electron microscopy (TEM), high-resolution TEM (HRTEM), and X-ray diffraction (XRD). These results declare that CdS semiconductor nanoparticles formed at the air/water interface change their morphologies and crystal structures during the ripening process due to dissolution and recrystallization of the particles.