• 한국의학물리학회지:의학물리
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• 제4권1호
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• pp.23-28
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• 1993

치료계획을 수행하는데 수반되는 isodose planning system 과 isodose calculation system, data set, equipment 등에 관한 치료계획의 성능관리에 대한 고찰을 시도하여 치료 오차의 한계를 최소화하여 치료행위의 정확성을 기하고자 한다.

• Radiation Oncology Journal
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• 제11권2호
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• pp.421-430
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• 1993

The calculation of dose distribution in multiple arc stereotactic radiotherapy is a three-dimensional problem and, therefore, the three-dimensional dose calculation algorithm is important and the algorithm's accuracy and reliability should be confirmed experimentally. The aim of this study is to verify the dose distribution of stereotactic radiosurgery experimentally and to investigate the effect of the beam quality, the number of arcs of radiation, and the tertiary collimation on the resulting dose distribution. Film dosimetry with phantom measurements was done to get the three-dimensional orthogonal isodose distribution. All experiments were carried out with a 6 MV X-ray, except for the study of the effects of beam energy on dose distribution, which was done for X-ray energies of 6 and 15 MV. The irradiation technique was from 4 to 11 arcs at intervals of from 15 to 45 degrees between each arc with various field sizes with additional circular collimator. The dose distributions of square field with linear accelerator collimator compared with the dose distributions obtained using circular field with tertiary collimator. The parameters used for comparing the results were the shape of the isodose curve, dose fall-offs fom $90\%$ to $50\%$ and from $90\%\;to\;20\%$ isodose line for the steepest and shallowest profile, and $A=\frac{90\%\;isodose\;area}{50\%\;isodose\;area-90\%\;isodose\;area}$(modified from Chierego). This ratio may be considered as being proportional to the sparing of normal tissue around the target volume. The effect of beam energy in 6 and 15 MV X-ray indicated that the shapes of isodose curves were the same. The value of ratio A and the steepest and shallowest dose fall-offs for 6 MV X-ray was minimally better than that for 15 MV X-ray. These data illustrated that an increase in the dimensions of the field from 10 to 28 mm in diameter did not significantly change the isodose distribution. There was no significant difference in dose gradient and the shape of isodose curve regardless of the number of arcs for field sizes of 10, 21, and 32 mm in diameter. The shape of isodose curves was more circular in circular field and square in square field. And the dose gradient for the circular field was slightly better than that for the square field.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.260-262
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• 2002

An accurate measurement of dose distribution is indispensable to perform radiation therapy planning. A measurement technique using a radiographic film, which is called a film dosimetry, is widely used because it is easy to obtain a dose distribution with a good special resolution. In this study, we tried to develop an analyzing system for the film dosimetry using usual office automation equipments such as a personal computer and an image scanner. A film was sandwiched between two solid water phantom blocks (30 ${\times}$ 30 ${\times}$ 15cm). The film was exposed with Cobalt-60 ${\gamma}$-ray whose beam axis was parallel to the film surface. The density distribution on the exposed film was stored in a personal computer through an image scanner (8bits) and the film density was shown as the digital value with NIH-image software. Isodose curves were obtained from the relationship between the digital value and the absorbed dose calculated from percentage depth dose and absorbed dose at the reference point. The isodose curves were also obtained using an Isodose plotter, for reference. The measurements were carried out for 31cGy (exposure time: 120seconds) and 80cGy (exposure time: 300seconds) at the reference point. While the isodose curves obtained with our system were drawn up to 60% dose range for the case of 80cGy, the isodose curves could be drawn up to 80% dose range for the case of 31cGy. Furthermore, the isodose curves almost agreed with that obtained with the isodose plotter in low dose range. However, further improvement of our system is necessary in high dose range.

• 한국의학물리학회지:의학물리
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• 제3권1호
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• pp.35-44
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• 1992

치료 계획에 필요한 선량분포의 2차원 및 3차원 그래픽 알고리즘을 개발하여 근접 치료 계획에 적용하였다. 상의 전개는 먼저, 원하는 선량치에 대한 등선량 입체 곡면을 그물망 형태(wire frame)로 전시하고 이를 임의의 방향에서 관찰할 수 있도록 회전 가능하게 하였다. 또한, 주요 세방향의 임의 단면에 대한 등선량 분포 곡선들을 전시 가능케 하므로써 전체적인 선량 분포에 대한 이해를 도왔다. 그 결과, 보다 확실하게 근접 치료시의 공간적인 선량분포를 이해할 수 있었다.

• Journal of Radiation Protection and Research
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• 제37권3호
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• pp.146-148
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• 2012

The use of GEANT4 simulation toolkit has increased in the radiation medical field for the design of treatment system and the calibration or validation of treatment plans. Moreover, it is used especially on calculating dose simulation using medical data for radiation therapy. However, using internal visualization tool of GEANT4 detector constructions on expressing dose result has deficiencies because it cannot display isodose line. No one has attempted to use this code to a real patient's data. Therefore, to complement this problem, using the result of gMocren that is a three-dimensional volume-visualizing tool, we tried to display a simulated dose distribution and isodose line on medical image. In addition, we have compared cross-validation on the result of gMocren and GEANT4 simulation with commercial radiation treatment planning system. We have extracted the analyzed data of dose distribution, using real patient's medical image data with a program based on Monte Carlo simulation and visualization tool for radiation isodose mapping.

• 대한디지털의료영상학회논문지
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• 제13권1호
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• pp.7-11
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• 2011

As applications of radiation grow wider from use in the early detection of lesions and preventive diagnosis purposes to the treatment of diseases, the possibilities for patients and working professionals to be exposed to radiation are becoming greater than ever. This can not only directly bring about an increase in patient's individual radiation exposure, but also brings about an increase in the annual radiation dose of working professionals. Therefore, research and countermeasures to reduce radiation dosage are required. In this study, space dosimetry has been divided into two separate measuments with an understanding of the increasing number of angiography procedures: front perspective and side perspective. According to the results of the isodose curve, a way to minimize radiation exposure in working professionals has been suggested. This was made possible by workers through awareness of suitable working positions.

• 대한방사선치료학회:학술대회논문집
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• 대한방사선치료학회 2005년도 춘계학술대회 초록집
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• pp.27-32
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• 2005

임상에서 일반적으로 행하여지는 전자선은 피부암과 유방암, 두 경부 등의 다양한 부위의 치료에 사용되어진다. 본 연구에서는 6 MeV에서 bolus 사용 시 source surface distance (SSD) setup과 source bolus distance (SBD) setup에 따른 선량분포를 비교하였고 electron field 내에 nipple이 존재하는 경우의 전자선 dose 분포, 그리고 광자선과 전자선을 같이 사용할 경우 junction 부위에서의 dose 분포를 비교하였다. 이러한 모든 실험은 파라핀 phantom과 acryl, film을 이용하여 dosimetry 를 시행하였고 임상에서와 같은 조건으로 setup 한 후 전자선 선량 분포를 확인하였다. Bolus 사용시의 SSD setup과 SBD setup의 경우 $8\%$의 선량분포 차이를 보였다. Nipple이 존재하는 field 내에서는 nipple 만큼 bolus를 제거하여야 균일한 선량 분포를 얻을 수 있음을 확인하였다. 또한 광자선과 전자선을 동시에 사용하는 경우에서는 전자선 field 전체에 bolus를 사용할 때 hot spot과 cold spot을 줄이는 효과를 얻을 수 있었다.

• Radiation Oncology Journal
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• 제2권1호
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• pp.101-106
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• 1984

Various methods are available for determination of exposure time in intracavitary radiotherapy of the carcinoma of the uterine cervix. To determine the accuracy of dose calculation with isodose curve for TAO applicator, comparison with results calculated by computer for radiotherapy treatment Planning was done in 24 procedures done in 12 consecutive patients with the carcinoma of the uterine cervix from May to December, 1983. The results are as follows: 1. The average dose rate Per hour of Point A was 87.70 rad, being 89.91 rad ana 85.49 rad in left and right, respectively. 2. The average percentage of dose rate of point A calculated by isodose curve method over that by computer was $101.28\%$ and the difference was less than $5\%$ in 17 Procedures and over $10\%$ in only 3 procedures. 3. The average percentage in case of point B was $108.67\%$. In conclusion, in most cases the difference was less than 200 rad for point A and less than 100 rad for point B during 2 courses of intracavitary radiotherapy. And so the dose rate calculation with isodose curve for TAO applicator is comparatively accurate.

• Nuclear Engineering and Technology
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• 제55권8호
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• pp.2734-2741
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• 2023

Brachytherapy is a special case of radiotherapy. It should be arranged according to some principles in medical radiation applications and radiation physics. The primary principle is to use as low as reasonably achievable dose in all ionizing radiation applications for diagnostic and therapeutic treatments. Dosimetric distributions are dependent on radioactive source properties and radiation-matter interactions in an absorber medium such as phantom or tissue. In this consideration, the geometrical structure and material of the seed capsule, which surrounds a radioactive material, are directly responsible for isodose profiles and dosimetric functions. In this study, the radiometric properties of capsule material were investigated on dose distribution in a water phantom by changing its nuclear properties using the EGSnrc Monte Carlo (MC) simulation code. Effective atomic numbers of hypothetic mixtures were calculated by using different elements with several fractions for capsule material. Model 6711 brachytherapy seed was modeled by EGSnrc/Dosrcnrc Code and dosimetric functions were calculated. As a result, dosimetric parameters of hypothetic sources have been acquired in large-scale atomic number. Dosimetric deviations between the data of hypothetic seeds and the original one were analyzed. Unit dose (Gy/Particle) distributions belonging to different types of material in seed capsule have remarkably differed from the original capsule's data. Capsule type is major variable to manage the expected dose profile and isodose distribution around a seed. This study shows us systematically varied scale of material type (cross section or effective atomic number dependent) offers selective material usage in production of seed capsules for the expected isodose profile of a specific source.

• Radiation Oncology Journal
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• 제11권2호
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• pp.439-448
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• 1993

Leksell 감마나이프(B-형)가 1992년 3월 경희대학교 의과대학 병원에 설치되었다. 선택적 빔 Plugging방법을 이용하여 정상 민감 조직에 대한 저선량 분포를 현저히 줄일 수 있으며, 또한 치료 부위에 더 좋은 선량 분포를 얻을 수 있다. 저선량에 대한 여러가지 선량 분포의 변화에 대한 연구를 하였으며, 사용중인 KULA프로그램의 선량 분포 곡선을 평가하기 위해 필름을 이용한 방사선량 계측을 실시하였고, RFA-3자동 밀도 측정기를 이용하여 평가하였다. 1992년 3월부터 1993년 2월까지 1년동안 100명의 환자중 17명의 환자에 선택적 빔 차폐 방법이 적용되었다. 고선량 영역에서는 측정값과 프로그램에서 제공된 선량 분포가 잘 일치하였다. 뇌하수체 선종의 치료시 치료 부위가 클 경우에는 본 연구 방법의 적용이 매우 중요시 되었으며, 반면에 치료 영역이 작을 경우에는 적절한 헬맷의 선택이 중요함을 알 수 있었다. 치료 환자의 중요 민감 장기의 방사선 선량 평가에서는 뇌간에 3~12 Gy, 시신경 교차에 3~11.2 Gy이었다. 중추신경계 영역의 최적화된 치료를 위하여 다양한 Plugging형태를 임상에 적용하는 것이 방사선에 민감한 정상 조직을 보호하기 위해 매우 중요한 인자가 됨을 알았다.