• The Korean Journal of Physiology and Pharmacology
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• v.11 no.2
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• pp.37-43
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• 2007

Adenosine has been reported to provide cytoprotection in the central nervous systems as well as myocardium by activating cell surface adenosine receptors. However, the exact target and mechanism of its action still remain controversial. The present study was performed to examine whether adenosine has a protective effect against $A{\beta}$-induced injury in neuroglial cells. The astrocyte-derived human neuroglioma cell line, A172 cells, and $A{\beta}_{25{\sim}35}$ were employed to produce an experimental $A{\beta}$-induced glial cell injury model. Adenosine significantly prevented $A{\beta}$-induced apoptotic cell death. Studies using various nucleotide receptor agonists and antagonists suggested that the protection was mediated by $A_1$ receptors. Adenosine attenuated $A{\beta}$-induced impairment in mitochondrial functional integrity as estimated by cellular ATP level and MTT reduction ability. In addition, adenosine prevented $A{\beta}$-induced mitochondrial permeability transition, release of cytochrome c into cytosol and subsequent activation of caspase-9. The protective effect of adenosine disappeared when cells were pretreated with 5-hydroxydecanoate, a selective blocker of the mitochondrial ATP-sensitive $K^+$ channel. In conclusion, therefore we suggest that adenosine exerts protective effect against $A{\beta}$-induced cell death of A172 cells, and that the underlying mechanism of the protection may be attributed to preservation of mitochonarial functional integrity through opening of the mitochondrial ATP-sensitive $K^+$ channels.

• Journal of the Korean Institute of Gas
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• v.6 no.4 s.18
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• pp.33-39
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• 2002

[ $9\%$ ] nickel steel LNG storage tank have double containments that can store cryogenic LNG independently. Inner tank material is used as $9\%$ nickel steel and outer tank is constructed by concrete. Comer protection which is installed on inner surface of concrete corner is consist of $9\%$ nickel steel liner and form glass insulator that make reduce tension at corner when LNG is leaked from inner tank. It is very difficult to design corner protection because expansion and contraction of liner make stress state complex. Corner protections of operating tank in KOGAS are designed by Japanese engineering company such as TKK, KHI and England company of WHESSOE. This paper is mainly focused on the integrity comparison of them according to requirements of Appendix 4 in ASME Section VIII Div. 2 by using FEM.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.38 no.8
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• pp.781-789
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• 2010

In the GPS/INS integrated system fault detection, algorithm based on a chi-square distribution is commonly used. In this paper, it has been proposed simplified GPS/INS fault detection algorithm that is combined conventional RAIM (Receiver Autonomous Integrity Monitor) and algorithm based on chi-square distribution for UAV using row-grade processor. It use a fault model to verify the proposed algorithm and produced the result.

• Journal of Positioning, Navigation, and Timing
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• v.11 no.4
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• pp.389-395
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• 2022

In order to ensure reliability the high-level automated driving such as Advanced Driver Assistance System (ADAS) and universal robot taxi provided by autonomous driving systems, the operation with high integrity must be generated within the defined Operation Design Domain (ODD). For this, the position and posture accuracy requirements of autonomous driving systems based on the safety driving requirements for autonomous vehicles and domestic road geometry standard are necessarily demanded. This paper presents localization requirements for safe road driving of autonomous ground vehicles based on the requirements of the positioning system installed on autonomous vehicle systems, the domestic road geometry standard and the dimensions of the vehicle to be designed. Based on this, 4 Protection Levels (PLs) such as longitudinal, lateral, vertical PLs, and attitude PL are calculated. The calculated results reveal that the PLs are more strict to urban roads than highways. The defined requirements can be used as a basis for guaranteeing the minimum reliability of the designed autonomous driving system on roads.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.4
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• pp.486-494
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• 2006

In order to protect the spermatozoa against cold shock, hen egg yolk is widely used as a cryoprotective agent in semen freezing extenders for domestic animals. The protective action of yolk is largely presumed to be due to low density lipoproteins (LDL). The effects of LDL on sperm quality of bull and northern pike (Esox lucius) after freezing-thawing have been reported, but no study has been made to evaluate the effect of LDL on boar sperm motility and other characteristics. The experiment was carried out to investigate the effect of LDL on the freezing of boar sperm in 0.25 ml straws. The aim was to evaluate the quality of boar spermatozoa cryopreserved in the presence of LDL. Motility of semen cryopreserved in LDL was analyzed and compared to semen cryopreserved with Tris-citric acid-glucose (TCG) and Tris-citric acid-fructose (TCF), two basic freezing extenders containing egg yolk. Similarly, acrosome and plasma membrane integrity were also evaluated and compared to semen cryopreserved with TCG and TCF. Analysis of sperm quality after freeze-thaw showed that the motility, acrosome and plasma membrane integrity were improved with LDL in the extender, as compared to the TCG and TCF. The highest post-thaw integrity of acrosome and plasma membrane and motility were obtained with 9% LDL (w/v). Consequently, the optimum LDL concentration in the extender was 9%. It is also suggested that the concentration of LDL addition is important for the effect on boar sperm protection during freezing and thawing. The percentage of motile spermatozoa was significantly higher after freezing in 9% LDL than in TCG and TCF 54.4% versus 30.4% and 30.1% (p<0.05), respectively. The integrity of acrosome and plasma membrane were also significantly higher at 70.3% and 50.5% respectively with semen frozen in 9% LDL extender compared to TCG at 37.8% and 30.3% and TCF at 36.4% and 29.9%, respectively (p<0.05),. In conclusion, we propose that extender containing LDL extracted from hen egg yolk could be used as a cryoprotective media with a better efficiency than TCG and TCF. LDL improved boar semen quality, allowing better spermatozoa motility, acrosome and plasma membrane integrity after the freeze-thaw process. Furthermore, we found out that the extender with 9% LDL concentration significantly enhanced motility, acrosome and plasma membrane integrity of boar sperm after freezing and thawing.

• ETRI Journal
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• v.29 no.6
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• pp.755-768
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• 2007

A very promising application of active RFID systems is the electronic seal, an electronic device to guarantee the authenticity and integrity of freight containers. To provide freight containers with a high level of tamper resistance, the security of electronic seals must be ensured. In this paper, we present the design and implementation of an electronic seal protection system. First, we propose the eSeal Protection Protocol (ePP). Next, we implement and evaluate various cryptographic primitives as building blocks for our protocol. Our experimental results show that AES-CBC-MAC achieves the best performance among various schemes for message authentication and session key derivation. Finally, we implement a new electronic seal system equipped with ePP, and evaluate its performance using a real-world platform. Our evaluation shows that ePP guarantees a sufficient performance over an ARM9-based interrogator.

• Corrosion Science and Technology
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• v.16 no.5
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• pp.235-240
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• 2017

Regional cathodic protection has significant impact on pipeline integrity management. After risk analyses of a newly built gas distribution station constructed in an area with large dwelling density, risk score was high because of potential threat caused by galvanic corrosion. Except reinforced steel in concrete, there are four kinds of metal buried under earth: carbon steel, galvanized flat steel, zinc rod and graphite module. To protect buried pipeline from external corrosion, design and construction of regional cathodic protection was proposed. Current density was measured with potential using potential dynamic test and boundary element method (BEM) was used to calculate current requirement and optimize best anode placement during design. From our calculation on the potential, optimized conditions for this area were that an applied current was 3A and anode was placed at 40 meters deep from the soil surface. It results in potential range between $-1.128V_{CSE}$ and $-0.863V_{CSE}$, meeting the $-0.85V_{CSE}$ criterion and the $-1.2V_{CSE}$ criterion that no potential was more negative than $-1.2V_{CSE}$ to cause hydrogen evolution at defects in coating of the pipeline.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.57 no.4
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• pp.706-714
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• 2008

In this paper, we suggest a practical and flexible system architecture for JTAG(Joint Test Action Group) protection of application processors. From the view point of security, the debugging function through JTAG port can be abused by malicious users, so the internal structures and important information of application processors, and the sensitive information of devices connected to an application processor can be leak. This paper suggests a system architecture that disables computing power of computers used to attack processors to reveal important information. For this, a user authentication method is used to improve security strength by checking the integrity of boot code that is stored at boot memory, on booting time. Moreover for user authorization, we share hard wired secret key cryptography modules designed for functional operation instead of hardwired public key cryptography modules designed for only JTAG protection; this methodology allows developers to design application processors in a cost and power effective way. Our experiment shows that the security strength can be improved up to $2^{160}{\times}0.6$second when using 160-bit secure hash algorithm.

• The Korean Journal of Archival Studies
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• no.10
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• pp.3-26
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• 2004

ISO 15489:2001 addresses the principles and requirements with which organizations, both public and private, should comply on the management of their records to ensure that adequate records are created, captured and managed. The standard defines the characteristics that a record should have through records management system as follows: authenticity, reliability, integrity, and usability. Authenticity means that records can be proven to be what it purports to be, to have been created or sent by the person purported to have created or sent it, and to have been created or sent at the time purported. Reliability means that the contents of the records can be trusted as a full and accurate representation of the transactions, activities or facts to which they attest and can be depended upon in the course of subsequent transactions or activities. Integrity refers to ensuring that a record is complete and unaltered. Usability means that records can be located, retrieved, presented and interpreted. In order to have these characteristics, a record should be persistently linked to the metadata necessary to document a transaction. Metadata is "data describing context, content and structure of records and their management through time." Metadata ensure the creation and maintenance of authentic, reliable and usable records and the protection of the integrity of those records. It could be implemented by creating and capturing records management metadata in systems that create and manage records. There have been some projects and standard initiatives to identify a core set of records management metadata. Included are the Australian Recordkeeping Metadata Standard and the British Metadata Standard which is part of the Requirements for Electronic Records Management System. Recently ISO/TS 23081-1 is published to implement metadata requirements within the framework of ISO 15489. Public records management system in Korea is ruled by the Act on the Management of Archives by Public Agencies and Administrative Records Management Regulation. This article evaluates records and their descriptive elements captured and maintained by the records management system in Korea on the basis of the international metadata standards.

• Journal of Positioning, Navigation, and Timing
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• v.5 no.4
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• pp.181-191
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• 2016

A Satellite Based Augmentation System (SBAS) provides differential correction and integrity information through geostationary satellite to users in order to reduce Global Navigation Satellite System (GNSS)-related errors such as ionospheric delay and tropospheric delay, and satellite orbit and clock errors and calculate a protection level of the calculated location. A SBAS is a system, which has been set as an international standard by the International Civilian Aviation Organization (ICAO) to be utilized for safe operation of aircrafts. Currently, the Wide Area Augmentation System (WAAS) in the USA, the European Geostationary Navigation Overlay Service (EGNOS) in Europe, MTSAT Satellite Augmentation System (MSAS) in Japan, and GPS-Aided Geo Augmented Navigation (GAGAN) are operated. The System for Differential Correction and Monitoring (SDCM) in Russia is now under construction and testing. All SBASs that are currently under operation including the WAAS in the USA provide correction and integrity information about the Global Positioning System (GPS) whereas the SDCM in Russia that started SBAS-related test services in Russia in recent years provides correction and integrity information about not only the GPS but also the GLONASS. Currently, LUCH-5A(PRN 140), LUCH-5B(PRN 125), and LUCH-5V(PRN 141) are assigned and used as geostationary satellites for the SDCM. Among them, PRN 140 satellite is now broadcasting SBAS test messages for SDCM test services. In particular, since messages broadcast by PRN 140 satellite are received in Korea as well, performance analysis on GPS/GLONASS Multi-Constellation SBAS using the SDCM can be possible. The present paper generated correction and integrity information about GPS and GLONASS using SDCM messages broadcast by the PRN 140 satellite, and performed analysis on GPS/GLONASS Multi-Constellation SBAS performance and APV-I availability by applying GPS and GLONASS observation data received from multiple reference stations, which were operated in the National Geographic Information Institute (NGII) for performance analysis on GPS/GLONASS Multi-Constellation SBAS according to user locations inside South Korea utilizing the above-calculated information.