• Journal of Life Science
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• v.31 no.10
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• pp.954-959
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• 2021

Apoptosis is an important mechanism that regulates cellular populations to maintain homeostasis, and the caspases, a family of cysteine proteases, are key mediators of the apoptosis pathway. Caspase-8 is an initiator caspase of the extrinsic apoptotic pathway, which is initiated by extracellular stimuli. Caspase-8 have two conserved domains, N-terminal tandem death effector domains (DED) and C-terminal two catalytic domain, which are important for this extrinsic apoptosis pathway. In extrinsic apoptosis pathway, death receptors which members of TNF superfamily are activated by binding of death receptor specific ligands from cell outside. After the activated death receptors recruit adaptor protein Fas-associated death domain protein (FADD), death domains (DD) of death receptor and FADD bind to each other and FADD combined with death receptor recruits procaspase-8, a precursor form of caspase-8. The DED of FADD and procaspase-8 bind to one another and FADD-bound procaspase-8 is activated by cleavage of the prodomain. This death receptor-FADD-caspase-8 complex called death inducing signaling complex (DISC). Cellular FLICE-inhibitory proteins (c-FLIPs) regulate caspase-8 activation by acting both anti- and pro-apoptotically, and caspase-8 activation initiates the activation of executioner caspases such as caspase-3. Finally activated executioner caspases complete the apoptosis by acting critically DNA degradation, nuclear condensation, plasma membrane blebbing, and the proteolysis of certain caspase substrates.

• Korean Journal of Ecology and Environment
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• v.54 no.3
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• pp.151-155
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• 2021

The application of environmental DNA in the domestic ecosystem is also accelerating, but the processing and analysis of the produced data is limited, and doubts are raised about the reliability of the analyzed and produced biological taxa identification data, and the sample medium (target sample, water, air, sediment, Gastric contents, feces, etc.) and quantification and improvement of analysis methods are also needed. Therefore, in order to secure the reliability and accuracy of biodiversity research using the environmental DNA of the domestic ecosystem, it is a process of actively using the database accumulated through ecological taxonomy and undergoing verification procedures, and experts verifying the resolution of the data increased by gene sequence analysis. This is absolutely necessary. Environmental DNA research cannot be solved only by applying molecular biology technology, and interdisciplinary research cooperation such as ecology-taxa identification-genetics-informatics is important to secure the reliability of the produced data, and researchers dealing with various media can approach it together. It is an area in desperate need of an information sharing platform that can do this, and the speed of development will proceed rapidly, and the accumulated data is expected to grow as big data within a few years.

• The Journal of the Korea Contents Association
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• v.21 no.9
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• pp.372-390
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• 2021

The objective of this study is to understand the current status of damage to Korean musical caused by the COVID-19, and also to seek for the coping measures and development direction in the post-Corona era. Thus, to understand the current status of damage, this study mainly researched the contents of NAVER TV musical performance transmitted for three years from March 2018 to February 2021 for analyzing the online performance and performance statistical data of Performing Arts Box Office Information System. As a result, this study could find a hypothesis and grounds to simultaneously verify and draw the positive and negative sides, pessimistic implications, and optimistic possibility. First, the performing arts would be multilaterally expanded after being divided into offline performance and online performance. Second, the utilization of online performance could narrow the gap(polarization) between capital area and non-capital area. Third, it is urgently needed to develop a win-win model for the establishment of a new musical market. Fourth, the performers' copyrights should be fairly protected. Fifth, the visualization requires the Korean-style support foundation and talent equipped with convergent thinking and knowledge. In such temporal changes from offline performance to online performance, there should be more sophisticated qualitative and quantitative growth in musical market.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.481-487
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• 2018

This paper proposes a method to detect and monitor the land creeping area using a UAV to analyze the damaged area efficiently. Using a UAV, it was possible to secure the safety of the investigators before the field survey and effectively utilize it to establish an investigation plan because an orthophoto can be used to detect and scale the cracks in a land creeping area. In addition, it was possible to analyze the scale of the crack quantitatively by extracting the topographic information from the orthophoto. The study sites were found to have a total crack area of 1.01 ha, a length of 1.07 km, an average width of 10 m, and a step distance of 1 to 10 m. Periodic UAV measurements can be used to detect displacements on the land creeping area and monitor the direction and scale of crack spread. Therefore, it is expected to be used effectively during recovery planning. Applying the UAV to the land creeping area resulted in the qualitative and quantitative results quickly and easily in dangerous mountainous watersheds. Therefore, it is expected that it will contribute to the development of related industries because of the high availability of a UAV in forest soil sediment disasters, such as landslides, debris flow, and land creeping area.

• The Journal of the Korea Contents Association
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• v.19 no.7
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• pp.384-392
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• 2019

Big data-related research that deals with the amount of explosive information in the era of the Fourth Industrial Revolution is actively underway. Big data is an essential element that promotes the development of artificial intelligence with a wide range of data that become learning data for machine learning, or deep learning. The use of deep learning and big data in various fields has produced meaningful results. In this paper, we have investigated the use of Big Data in the cultural arts industry, focusing on video contents. Noteworthy is that big data is used not only in the distribution of cultural and artistic contents but also in the production stage. In particular, we first looked at what kind of achievements and changes the Netflix in the US brought to the OTT business, and analyzed the current state of the OTT business in Korea. After that, Netflix analyzed the success stories of 'House of Cards', which was produced / circulated through 'Deep Learning' cinematique, which is a prediction algorithm, through accumulated customer data. After that, FGI (Focus Group Interview) was held for cultural and artistic contents experts. In this way, the future prospects of Big Data in the domestic culture and arts industry are divided into technical aspect, creative aspect, and ethical aspect.

• Korean Journal of Remote Sensing
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• v.35 no.2
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• pp.337-342
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• 2019

This letter describes the development of WRI (Wildfire Risk Index) using GDAPS (Global Data Assimilation and Prediction System) and satellite data, and its application to the Goseong-Sokcho and Gangneung-Donghae wildfires in April 4, 2019. We made sure that the proposed WRI represented the change of wildfire risk of around March 19 and April 4 very well. Our approach can be a viable option for wildfire risk monitoring, and future works will be necessary for the utilization of GK-2A products and the coupling with the wildfire prediction model of the Korea Forest Service.

• Korean Journal of Environmental Biology
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• v.36 no.4
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• pp.576-583
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• 2018

Investigation of optimal temperature, irradiance and photoperiod conditions for free-living gametophytes of Saccharina sculpera for natural resources conservation and mass cultivation of endangered species in the eastern coast of Korea. Induction of regeneration and maturation of the free-living gametophytes of S. sculpera were cultured at temperatures (5, 10, 15, 20 and $25^{\circ}C$), irradiance (10, 20, 40, 60 and $80{\mu}mol\;photons\;m^{-2}\;s^{-1}$ and photoperiods (14:10, 12:12 and 10:14 h L:D). The female gametophyte were actively regenerated without reaching sexual maturity under $10^{\circ}C$, $20{\mu}mol\;photons\;m^{-2}\;s^{-1}$ and 12:12 h (L:D) conditions. In contrast, the conditions for male gametophytes were slightly different at $15^{\circ}C$, $10{\mu}mol\;photons\;m^{-2}\;s^{-1}$ and 12:12 h (L:D). The sexual maturation of female and male gametophytes took place under $15^{\circ}C$, $40{\mu}mol\;photons\;m^{-2}\;s^{-1}$, 14:10 h (L:D) and $10^{\circ}C$, $20{\mu}mol\;photons\;m^{-2}\;s^{-1}$, 10:14 h (L:D), respectively. These results provide basic information for controlling the regeneration and maturation of free-living gametophytes for conservation and utilization of S. sculpera.

• Korean Journal of Heritage: History & Science
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• v.52 no.3
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• pp.146-159
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• 2019

This study focuses on the understanding of human subsistence and pottery use during ancient times on the Korean peninsula through lipid analysis of potsherds from several major prehistoric settlement sites. Ancient human subsistence has been one of the long-standing topics in Korean archaeology. However, since the high acidity of sediments does not allow long-term preservation of organic remains, we still lack some critical information related to the prehistoric diet. Pottery contains relatively well-preserved organic remains created during past cooking events. Though pottery is one of the most studied material cultures in Korean archaeology, almost no attention has been given to analyzing the pottery itself. This is a surprising omission and represents a serious gap in our understanding of prehistoric technology and subsistence. The analysis of ancient lipids extracted from the pottery matrix using GC-MS and isotope analysis can contribute to our understanding of the true nature of past subsistence strategies. Potsherd samples for the analyses in this study were collected from six prehistoric and early historic settlement sites located in the central part of the Korean peninsula. The results showed that subsistence strategies differed by both location and time period. For example, at Jungdo, an inland open-air Bronze Age settlement site in Chuncheon City, we were able to see the presence of terrestrial mammals. At Gahak-dong, Gwangmyeong City, marine resources were utilized, as the location of the site is not far from the coastline. At the early historic site of Guwol-dong, Incheon City, we were able to detect dairy products. The results of this study suggest that there was utilization of a wider range of resources among ancient dwellers in the central part of the Korean peninsula.

• Journal of Convergence for Information Technology
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• v.9 no.6
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• pp.112-120
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• 2019

The purpose of this study is to explore educational methods for elementary, middle and high schools using school forests via IT convergence. To this aim, we reviewed the previous literature on education using school forests to identify the problems with the existing education using school forests, and conducted interviews with experts to analyze the demands. we proposed an educational method that can utilize the school forests via IT convergence, and explored its validity through content reviews conducted by experts. The findings of this study are as follows. First, we proposed the IT convergence instruction focused on hands-on activities on top of the existing educational contents. Second, we proposed IT convergence instruction that incorporates diverse materials, physical computing tools, and programming tools. Third, we presented methods for utilizing such IT convergence instruction in connection with various elements of the 2015 Revised Curriculum as well as with various other activities such as middle school free semester activities and after-school activities. The school forest is a crucial learning space for the areas related to agriculture and biotechnology. Thus, we anticipate that the IT convergence instruction proposed in this study will lead to the re-discovery and re-evaluation of a value of school forests as an educational space that contributes to fulfilling the objective of the 2015 Revised Curriculum to nurture creative convergent talent.

• Journal of Internet Computing and Services
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• v.19 no.6
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• pp.21-29
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• 2018

In the era of the 4-th industrial revolution, the concept of smart factory is emerging. There are efforts to predict the occurrences of facility errors which have negative effects on the utilization and productivity by using data analysis. Data composed of the situation of a facility error and the type of the error, called the facility error log, is required for the prediction. However, in many manufacturing companies, the types of facility error are not precisely defined and categorized. The worker who operates the facilities writes the type of facility error in the form with unstructured text based on his or her empirical judgement. That makes it impossible to analyze data. Therefore, this paper proposes a framework for constructing a phrase network to support the identification and classification of facility error types by using facility error logs written by operators. Specifically, phrase indicating the types are extracted from text data by using dictionary which classifies terms by their usage. Then, a phrase network is constructed by calculating the similarity between the extracted phrase. The performance of the proposed method was evaluated by using real-world facility error logs. It is expected that the proposed method will contribute to the accurate identification of error types and to the prediction of facility errors.