• Journal of The Korean Astronomical Society
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• v.24 no.2
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• pp.151-159
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• 1991

Using the photographic imagery of the SO galaxy NGC 5102, the equivalent luminosity profile and the fractional integrated luminosity curve have been derived. Several photometric parameters of the galaxy, such as a total magnitude ($B_T$), equivalent radius ($r^*_e$), effective surface brightness (${\mu}^*_e$), and concentration indices ($C_{21}$, $C_{32}$) were derived from the luminosity profiles. According to the decomposition method from the nonlinear least squares fitting, photometric parameters of the bulge (${\mu}_e$, $r_e$) and the exponential disk (${\mu}(0)$, ${\alpha}^{-1}$), and the bulge to total luminosity ratio (B/T) were obtained. The derived central disk surface brightness (${\mu} (0)\;=\;22.06\;{\pm}\;0.18\;mag/\Box"$) and the evaluated B/T ratio (= 0.52) of the NGC 5102 are close to the mean values (${\mu} (0)\;=\;21.65\;{\pm}\;0.3\;mag/\Box"$, B/T=0.63) of the SO galaxies. Analysis showed that a lens-like hump is embedded in the equivalent luminosity profile of the NGC 5102.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.1
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• pp.1-14
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• 2011

Objectives: The purpose of this study was to investigate the anti-inflammatory effects of aqueous extract from Picrasmae Lignum(PL). Methods: To evaluate the anti-inflammatory effects of PL extract, the productions of NO, PGE2 and expression of pro-inflammatory cytokine(IL-1b, IL-6 and TNF-a) were measured in LPS-induced RAW 264.7 cells. Furthermore Western blot analysis has been done to look into the inhibitory mechanisms such as MAPKs and NF-kB. Results: PL extract down-regulated LPS-induced NO, PGE2, IL-1b, IL-6 and TNF-a productions mainly through JNK and p38 MAPK pathway and NF-kB pathway. Conclusions: These results suggest that PL extract may be effective for the treatment of inflammatory diseases.

• Bulletin of the Korean Chemical Society
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• v.22 no.1
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• pp.25-29
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• 2001

Nucleophilic substitution reactions of O-imidomethyl derivatives of phenols with OH- were studied theoretically using the semiempirical AM1 and Solvation Model 2.1 (SM2.1) methods in the gas phase and aqueous solution, respectively. In the gas phase, the two reaction paths, in which the imide (1a) or phenol (1b) is functioning as a leaving group, can occur competitively. In contrast, in aqueous solution, path (1b) becomes more favorable than (1a) because the transition states (TS) of path (1b) are more stabilized by solvent. Differences in solvation energies are caused by the structural differences of TS, i.e., the TS via path (1b) is more dissociative than that via path (1a). Therefore we conclude that the solvent effects play an important role in the hydrolysis of O-imidomethyl derivatives of phenols. However, reactivity is dependent on the acidities of both the imide and the phenol fragments since the ρz values vary progressively from 4.2 (Z' = I) to 2.5 (Z' = IV) as the acidities of imide increase. These are in good agreement with the experimental results.

• Biomolecules & Therapeutics
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• v.18 no.3
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• pp.300-307
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• 2010

Photosensitized peroxidation of membrane lipids has been implicated in skin pathologies such as phototoxicity and premature aging. We have previously reported that syriacusin compounds isolated from Hibiscus Syriacus inhibited lipid peroxidation. Here, we investigated whether syriacusins could be effective inhibitor to skin aging using ultraviolet-irradiated human dermal fibroblast cells (HDFCs). Syriacusins A, B, and C inhibit the activity of human neutrophil elastase (HNE), a serine protease to degrade extracellular matrix (ECM) proteins including elastin, with $IC_{50}s$ of 8.0, 5.2, and $6.1\;{\mu}M$, respectively. No changes in cell viability were detected by syriacusins A and B in UV-B ($10\;mJ/cm^2$) irradiated HDFCs. Matrix metallo-proteinase (MMP)-1 expression in HDFCs was increased by UV-B irradiation. MMP-1 expression in UV-B irradiated HDFCs was decreased by $10\;{\mu}M$ and $20\;{\mu}M$ syriacusin A to 50% and 20% of untreated control, respectively. Syriacusin B treated with $20\;{\mu}M$ reduced MMP-1 expression in UV-B irradiated HDFCs to 60% of untreated control. Syriacusin A also inhibited MMP-2 expression accompanying the increase of type-I pro-collagen in UV-B irradiated HDFCs. These results demonstrate that syriacusin A could be a more effective compound to inhibit skin aging caused by UV irradiation. It suggests that syriacusins A and B might be developed as possible agents to treat or prevent skin aging.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.7
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• pp.1529-1536
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• 2010

In this paper, we propose a Axially displaced ellipse gregorian antenna with conical feed horn operating in Ku-band. For fast searching satellite position, it is designed the sub-reflector rotates about $1.5^{\circ}$ tilted by the central axis. the curvature and feed center of the main-reflector and sub-reflector are optimized to achieve maximum antenna efficiency. The designed reflector antenna shows the gain of 33dB and the cross polarization level of less than -21dB and the side-lobe level of less than －14 dB at 12.2 GHz. and C/N ratio of 19dB is proved by reception experiment of Koreasat with fabricated antenna.

• Journal of the Society of Naval Architects of Korea
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• v.39 no.1
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• pp.8-15
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• 2002

A two-dimensional higher order panel method using B-splines has been developed to overcome the disadvantages of the low order panel method and to obtain more accurate solution. The sources and the normal dipoles are distributed on both the body and the free surface. Instead of applying the upwind finite difference schemes to satisfy the linearized free surface and the radiation condition, the derivatives of the basis functions of the B-splines are directly applied to the linearized free surface condition. Numerical damping in the Dawson's method are avoided in the Present computations. In order to validate the present method, numerical computations are carried out for a submerged cylinder and a two-dimensional hydrofoil steadily moving beneath a free surface. The numerical results show that fast convergence and better accuracies have been achieved by the present method.

• Natural Product Sciences
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• v.20 no.4
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• pp.227-231
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• 2014

Cimicifuga heracleifolia extract (CHE) was investigated for its effects on the release of nitric oxide (NO) and at the level of inducible nitric oxide synthase (iNOS) gene expression in mouse macrophages. We found that C. heracleifolia elicited a dose-dependent increase in NO production and the level of iNOS mRNA. Since, iNOS transcription has been shown to be under the control of the transcription factor $NF-{\kappa}B$, the effects of CHE on $NF-{\kappa}B$ activation were examined. Transient expression assays with $NF-{\kappa}B$ binding sites linked to the luciferase gene revealed that the increased level of iNOS mRNA, induced by CHE, was mediated by the $NF-{\kappa}B$ transcription factor complex. By using DNA fragments containing the $NF-{\kappa}B$ binding sequence, CHE was shown to activate the protein/DNA binding of $NF-{\kappa}B$ to its cognate site, as measured by electrophoretic mobility shift assay. These results demonstrate that C. heracleifolia stimulates NO production and is able to up-regulate iNOS expression through $NF-{\kappa}B$ transactivation.

• IEIE Transactions on Smart Processing and Computing
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• v.2 no.2
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• pp.97-101
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• 2013

Bit-depth expansion is a process of enhancing the image quality by increasing the number of intensity levels. To solve this problem, a hybrid method is proposed, where the pixels are categorized into smooth and complex regions, and are processed using different methods. The pixels in the smooth region are reconstructed with a smooth prior, and a Bayesian estimator is used for the pixels in the complex region. The proposed method effectively removes the false contour artifacts while requiring less computation than conventional methods. In addition, the method shows good quantitative performance, and the PSNR gains over the best existing method are 1.45 dB and 0.26 dB for 4 bits and 3 bits expansion cases, respectively.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.22 no.1
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• pp.104-112
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• 1998

The mold filling process has been a central issue in the development of numerical methods to solve the casting processes. A mold filling which is inherently transient free surface fluid flow, is important because the quality of casting highly depends on such phenomenon, Most of the existing numerical schemes to solve mold filling process have severe limitations in time step restrictions or Courant criteria since explicit time integration is used. Therefore, a large computation time is required to analyze casting processes. In this study, the well known SOLA-VOF method has been modified implicitly to simulate the mold filling process. Solutions to example filling problems show that the proposed method is more efficient in computation time than the original SOLA -VOF method.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.1
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• pp.102-113
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• 2000

In this study, a three-dimensional gravity casting problem has been examined to investigate a coupled phenomenon of the filling and solidification process. This work simultaneously considers the two key phenomena of metal casting : the fluid flow during mold filling, and solidification process. The VOF method is used to analyze the free surface flow during filling and the equivalent specific heat method is employed to model the latent heat release during solidification. The time-implicit filling algorithm is applied to save the computational time for analyzing the mold filling process. The three-dimensional benchmark problem used in the MCWASP VII has been solved using both the implicit and explicit algorithm, and the present results are compared with the benchmark experimental results and the other numerical results.