• Title/Summary/Keyword: Hye-seok

Search Result 2,047, Processing Time 0.033 seconds

Detection of Epstein-Barr virus in the inflammatory and neoplastic uterine cervical lesions (자궁경부의 염증 및 종양병변에서 Epstein-Barr 바이러스의 검출)

  • Jeong, Hye-Jin;Lee, Eung-Seok;Lin, Zhen-Hua;Park, Seol-Hee;Kang, Jae-Sung;Kim, In-Sun
    • The Korean Journal of Cytopathology
    • /
    • v.12 no.2
    • /
    • pp.73-80
    • /
    • 2001
  • The prevalence of Epstein-Barr virus(EBV) in the uterine cervix was investigated to define the possible etiologic role in cervical carcinogenesis. The viral genotyping and LMP-1 30bp deletion were also stooled. The materials included 169 uterine cervical swabs(152 within normal limits, 12 atypical squamous cells of uncertain significance, 3 low grade intraepithelial lesions, and 2 high grade squamous intraepithelial lesion) and 104 uterine cervical tissues obtained from hysterectomy specimens(32 carcinoma in situ, 9 microinvasive squamous cell carcinomas, 37 invasive squamous cell carcinomas, 7 adenocarcinomas, 7 adenosquamous carcinomas, and 12 cervicitis). EBV detected by PCR for EBNA-1 was positive in 52(56.5%) of 92 invasive and noninvasive cervical carcinomas, and 80(48.8%) of 164 inflammatory or normal cervices. The viruses detected in carcinomas were all type A, and LMP-1 30bp deletion form was more frequent in premalignant and malignant cervical lesions than in nonneoplastic cervices. From the above results, it may be concluded that EBV is one of common viruses detected in uterine cervix of Korean women, and type A virus and LMP-1 30bp deletion form may have a role in cervical carcinogenesis.

  • PDF

Pressure Sensitive Device Using Conductive and Porous Structures (전도성 다공성 구조 압력감지소자)

  • So, Hye-Mi;Park, Cheolmin;Chang, Won Seok
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.38 no.7
    • /
    • pp.601-605
    • /
    • 2014
  • Porous conductors are known to demonstrate excellent electrical, mechanical, and chemical resistance. These porous conductors demonstrated potential applications in various fields such as electrodes for supercapacitors, flexible heaters, catalytic electrodes, and sorbents. In this study, we described a pressure sensitive device using conductive and porous sponges. With an extremely simple "dipping and drying" process using a single-walled carbon nanotube (SWCNT) solution, we produced conductive sponges with sheet resistance of < $30k{\Omega}/sq$. These carbon nanotube sponges can be deformed into any shape elastically and repeatedly compressed to large strains without collapse. The pressure sensors developed from these sponges demonstrated high resistance change under pressure of up to a half of their initial resistance.

A Comparative Study on the Body Types between the Koreans Living in Russia and China -With the Focus on the Women in their 60's- (러시아와 중국 거주 한국인의 체형 비교 연구 -60대 여성을 중심으로-)

  • Im, Soon;Seok, Hye-Jung
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.31 no.5 s.164
    • /
    • pp.813-825
    • /
    • 2007
  • The purpose of this paper lies in the comparison of the body types between the subjects of Korean women in their 60's living in Russia and China. The findings are as follows. 1. The comparison of 80 items in physical measurements between the Korean women in their 60's living in Russia and China resulted in the differences in 57 items. While the height items including stature between them showed negligible differences, most of the length items relating to width, thickness, circumference, and obesity showed differences, which were big. 2. The analysis by using the physical measurements showed the differences in the number of the elements constituting the body types of the Korean women in their 60's, as 13 for those living in Russia and 11 for those living in China. 3. The cluster analysis for the comparison of the body types of each group, by categorizing the body types, produced three types for both groups. Koreans living in Russia were grouped as those with the short stature and light weight, the medium stature and medium weight, and the tall stature and heavy weight. Koreas living in China were classified as those with the short stature and medium weight, the tall stature and light weight, and the tall stature and heavy weight.

Novel Single-Nucleotide Polymorphisms of SOHLH2 in Korean Patients with Premature Ovarian Failure

  • Jeong, Ji-Hye;Choi, Mi-Kyung;Won, Hyung-Jae;Song, Seung-Hoon;Kim, You-Shin;Lyu, Sang-Woo;Seok, Hyun-Ha;Park, Mi-Ree;Kim, Nam-Keun;Yoon, Tae-Ki;Shim, Sung-Han;Choi, Young-Sok
    • Development and Reproduction
    • /
    • v.15 no.4
    • /
    • pp.309-313
    • /
    • 2011
  • SOHLH2 is a novel germ cell-specific transcription factor that is crucial for folliculogenesis in the ovary and spermatogenesis in the testis. SOHLH2 represents a candidate gene for infertility with premature ovarian failure. We analyzed whether mutations in the SOHLH2 gene in 98 Korean women with premature ovarian failure. The sequence analysis identified six novel SNPs (c.431-41G>C, c.656A>T, c.1000+27C>T, c.1000+33G>T, c1258-106G>A, and c.2094+ 11T>C) from Korean patients with premature ovarian failure. The c.656A>T found in exon 7 results in change of an amino acid, tyrosine to phenylalanine. Functional mutations in SOHLH2 gene are rare in Korean women with premature ovarian failure.

Comparative Analysis of the Morphometric Changes in Ussurian bullhead, Leiocassis ussuriensis, and Korean bullhead, Pseudobagrus fulvidraco, in the Early Period of Growth

  • Lim, Sang Gu;Han, Hyoung Kyun;Kang, Jung Ha;Park, Hye Jung;Oh, Ji Su;Lim, Ji Su;Goo, In Bon;Park, In-Seok
    • Development and Reproduction
    • /
    • v.17 no.3
    • /
    • pp.257-268
    • /
    • 2013
  • Morphometric changes in the Ussurian bullhead, Leiocassis ussuriensis, and the Korean bullhead, Pseudobagrus fulvidraco, were observed during the early period of growth. Yolk length, yolk height, and yolk volume in the two species decreased within 9 days post-hatching (DPH) (p<0.05). The body lengths and body heights of both species increased gradually to 150 and 130 DPH, respectively (p<0.05). The horizontal distance between the anteriormost extension of the head and the anterior insertion of the pectoral fin, the anteriormost extension of the head ${\times}$ the verticality position of the anterior insertion of the primary dorsal fin rays, and the anterior insertion of the primary dorsal fin ${\times}$ the anterior insertion of the pectoral fin were greater in the Korean bullhead than in the Ussurian bullhead (p<0.05). However, the relative sizes of the head region, pectoral fin, ventral fin, and anal fin were greater in the Ussurian bullhead than in the Korean bullhead (p<0.05), and relative body depth and the size of the outer-mandible barbel were greater in the Korean bullhead than in the Ussurian bullhead (p<0.05). The growth curves of the morphometric characteristics of both species were divided into three types.

Transverse Low Velocity Impact Failure Behavior of Triaxial Braided Composite Tube with Different Braiding Angles (Triaxial braiding 기술을 이용한 원형 튜브의 횡방향 저속충격파괴 거동분석)

  • Sim, Ji-hyun;Park, Sung-min;Kim, Ji-hye;Shin, Dong-woo;Chon, Jin-sung;Kim, Jae-kwan;Bae, Jin-Seok
    • Textile Coloration and Finishing
    • /
    • v.28 no.4
    • /
    • pp.246-252
    • /
    • 2016
  • In comparison to metal alloys, braided composite features a high impact resistance and crash energy absorption potential, and also it still remained competitive stiffness and strength properties. Braiding angle is one of the most important parameters which affect the mechanical behaviors of braided composite. This paper presents transverse low velocity impact failure behavior analysis on the carbon 3D triaxial braided composite tube with the braiding angle of $20^{\circ}$, $50^{\circ}$ and $80^{\circ}$. The flexural behaviour of 3D triaxial braided composite tube under bending loads was studied by conducting quasistatic three point bending test. Also, the low velocity impact responses of the braided composite tubes were also tested to obtain load-displacement curves and energy absorption. Consequently, the increase of the braided angle, the peak load also increases owing to the bigger bending stiffness.

Mechanical Characteristics of CF Laminated Prepreg with UV-thermal Dual Curable Epoxy Resin (광·열경화형 수지를 이용한 탄소섬유 프리프레그의 물리적 특성)

  • Sim, Ji-hyun;Kim, Ji-hye;Park, Sung-min;Koo, Kwang-hoe;Jang, Key-wook;Bae, Jin-seok
    • Textile Coloration and Finishing
    • /
    • v.29 no.1
    • /
    • pp.37-44
    • /
    • 2017
  • An issue of major concern in the utilization of laminated composites based epoxy resin is associated with the occurrence of delaminations or interlaminar cracks, which may be related to manufacturing defects or are induced in service by low-velocity impacts. A strong interfacial filament/brittle epoxy resin bonding can, however, be combined with the high fracture toughness of weak interfacial bonding, when the filaments are arranged to have alternate sections of shear stress. To improve this drawback of the epoxy resin, UV-thermal dual curable resin were developed. This paper presents UV-thermal dual curable resin which were prepared using epoxy acrylate oligomer, photoinitiators, a thermal-curing agent and thermoset epoxy resin. The UV curing behaviors and characteristics of UV-thermal dual curable epoxy resin were investigated using Photo-DSC, DMA and FTIR-ATR spectroscopy. The mechanical properties of UV-thermal dual curable epoxy resin impregnated CF prepreg by UV curable resin content were measured with Tensile, Flextural, ILSS and Sharpy impact test. The obtained results showed that UV curable resin content improves the epoxy toughness.

Isolation, Purification and Characterization of the β-Xylosidase from Klebsiella sp. Sc. (Klebsiella sp. Sc가 생산하는 β-xylosidase의 분리, 정제 및 특성)

  • Lee, Yong-Seok;Park, In-Hye;Ahn, Soon-Cheol;Choi, Yong-Lark
    • Journal of Life Science
    • /
    • v.20 no.12
    • /
    • pp.1801-1806
    • /
    • 2010
  • A $\beta$-xylosidase encoding gene from Klebsiella sp. Sc was cloned in Escherichia coli. The $\beta$-xylosidase gene consisted of an open reading frame of 1,680 nucleotides and encodes 559 amino acids with a deduced molecular weight of 63 kDa. The deduced amino acid sequence of the $\beta$-xylosidase from Klebsiella sp. Sc exhibits 90% identities and 95% positives compared to those from Klebsiella oxytoca (KOX), Lactobacillus lactis (LAC, 82%, 90%), Bacillus longum (BLON, 69%, 81%) and Escherichia coli (ECOLI, 47%, 63%). The $\beta$-xylosidase was purified by GST-fusion purification system. The pH and temperature optima of the enzyme were 6.6 and $55^{\circ}C$, respectively. The $\beta$-xylosidase hydrolyzes xylobiose to xylose.

Papillomatosis on the skin of the wild marbled sole Pleuronectes yokohamae (자연산 문치가자미, Pleuronectes yokohamae 피부의 육아종)

  • Park, Jung-Jun;Byoun, Ju-Young;Choi, Hye-Sung;Park, Myoung-Ae;Kwon, Mun-Gyeong;Kim, Seok-Ryel
    • Journal of fish pathology
    • /
    • v.24 no.3
    • /
    • pp.213-223
    • /
    • 2011
  • Among wild marbled sole, Pleuronectes yokohamae caught in west coastal area, Chungnam, tumor-bearing fish were found. Parasites and pathogenic bacteria were not detected and CPE was not observed. Using the light microscope, the epidermal layer of wild P. yokohamae was significantly thickened compared to the normal skin. The lesion was formed papillary folds. Hypertropical epithelial cells revealed karyolysis, marked nucleolus and cloud swelled cytoplasm. In the epidermal layer of the lesion, X-cell that is characterized by oval and small pale nucleus and prominent nucleolus was observed. Dermal layer had newly formed vessels. The size of mucous cell in the papilloma lesion was significantly increased compared to the normal. In this study, no pathogens were found, so future works for finding cause of the papilloma in the P. yokohamae are needed.

Histopathological observation of the crucian carp Carassius auratus with infected leech Limnotrachelobdella sinensis by scanning electron microscope (주사전자현미경을 이용한 거머리, Limnotrachelobdella sinensis 감염 붕어, Carassius auratus의 조직병리학적 관찰)

  • Park, Jung-Jun;Byoun, Ju-Young;Kim, Jung-Ho;Choi, Hye-Sung;Park, Myoung-Ae;Kim, Seok-Ryel
    • Journal of fish pathology
    • /
    • v.24 no.3
    • /
    • pp.205-211
    • /
    • 2011
  • All of the crucian carp, Carassius auratus and 50% of common carp. Cyprinus carpio examined in this study were infected with the leeches, Limnotrachelobdella sinensis. Especially, the infection of C. carpio with L. sinensis was the first report in Korea. The gill of C. auratus showed increased hydrophic degeneration of epithelial cell in the filament, blood congestion, hyperplasia of epithelial cell in the filament and lamellae. In the SEM observation, gill filament was transformed to the cylinder form by the lamellae fusion. The lamellae surface showed degeneration, fragmentation of microridges. The extracellular cartilaginous matrix of the filaments was exposed by the collapse of epidermal layer. In the 18S rRNA analysis of L. sinensis, the relationships among these groups are not clear and not concord with their morphological classification.