• Journal of the Korean Society for Library and Information Science
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• v.36 no.4
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• pp.49-67
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• 2002

School libraries are one of the essential parts for high quality education. The Seventh Educational Cumiculum emphasizes the development of creative and autonomous students who can solve problems in a self-directed way. The Ministry of Education and Human Resources Development come into forcing the installation of school digital library since 2001. Also, the Ministry of Education and Human Resources Development has presented the Master Plan of School's Activation in July 2002. In this situation, the research and discussion on effective model of school digital library are very important. Thus, This study aims to design a model of school digital library differentiated School's sizes depending on primary and secondary school's current status. This study is proposed 4 facility model of school digital library based differentiated school's sizes and designed A-type, B-Type model on individual model.

• Korean Journal of Environmental Agriculture
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• v.28 no.4
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• pp.462-467
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• 2009

Exposure of formaldehyde (FA), one of the major compounds in pesticides and in the onset of sick house syndrome, has been implicated in the development of diverse diseases. Liver is a very important organ to body metabolism and drug detoxification. Apotosis of hepatocytes is associated with the onset of liver diseases such as hepatitis. However, the apoptotic effect of FA in hepatocytes is not clear. Therefore, this study was conducted to investigate the effect of FA on the apoptosis in HepG2 cells, a human hepatocyte cell line. As a result, FA (> $500\;{\mu}M$) decreased cell viability and increased lactate dehydrogenase activity in HepG2 cells, which was blocked by the treatment of vitamin E and N-acetylcysteine (NAC). In addition, FA decreased glutathione (GSH) contents and Bcl-2 levels, while increasing lipid peroxide formation and Bax levels. It also cleaved caspase-3 form, which was blocked by the treatment of vitamin E and NAC. It is insisted that FA induced apoptosis via oxidative stress in human hepatocytes.

• Journal of Animal Science and Technology
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• v.63 no.3
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• pp.593-602
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• 2021

Mammalian milk including microRNAs (miRNAs) as a novel class of noncoding RNAs, that can be transferred to infants and it plays on a critical role in biological functions such as immune regulation and development. However, the origin and functional importance of milk-derived miRNAs are still undetermined. This study applied RNA sequencing to explore the featured profiles of miRNA expression in colostrum and mature milk-originated exosomes from human, bovine, and caprine milk. These dietary exosome-derived miRNAs are highly conserved in human, bovine and caprine milk. Interestingly, abundant miRNAs expressed in human milk are similarly conserved across species. In addition, we confirmed that immune-related miRNAs (miR-30a-5p, miR-22-3p, and miR-26a) are commonly observed in the colostrum and mature milk of cows and caprines as well as humans. Our results provide new insights and resources for investigating the functionality of immune-associated miRNAs and evaluating physiological and biological condition in human, bovine and caprine milk as biomarkers.

• The Journal of Korean Association of Computer Education
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• v.20 no.1
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• pp.75-86
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• 2017

E-learning has become one of the popular educational method in these day. In recognition of the growing e-learning, numerous researchers of S&T have utilized for the training aimed at enhancing competency. In the circumstances, previous studies have yield interesting results regarding certain factors that competency based programs may increase effectiveness of education. Therefore this research described here contributes to design competency modeling and education roadmap for human resource in S&T. The study uses survey, FGI, delphi technique, and expert workshop for selecting the main competencies. In particular, the results are including training roadmap of 5 level in each of two groups as researchers and S&T managers. These findings can be possible to develop customized programs and supported long-term career development path plan for human resource in S&T.

• Proceedings of the SAREK Conference
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• 2008.06a
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• pp.1392-1397
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• 2008

This study is to measure the change of the $CO_2$ and floating dust concentration depending on the volume of the ventilation and the state of on/off the ventilation for the estimation of the air pollution in classroom. The results could be summarized as follows: the test cell was the two full scaled model and the one is set up with ventilation system another was not. the volume of classroom is 170.1m3 and the number of persons are 35. 1)when the ventilation system was not installed, The experimental results of the $CO_2$ concentration showed the average of 2,150ppm and the maximum of 2,740ppm in the classroom. This was the higher than 1,000ppm, the standard value of ASHRAE and the enforcement regulations of School Sanitation Code in Ministry of Education & Human Resources Development, 1000ppm. The $CO_2$ concentration was relatively increasing during school hours. 3)In case of the volume of ventilation of $800m^3$/h, the $CO_2$ concentration of classroom showed the average of 962 ppm and the maximum of 1,380 ppm. This was higher than 1,000ppm, the standard of ASHRAE and the enforcement regulations of School Sanitation Code in Ministry of Education & Human Resources Development. 4)The floating dust(PM10) was the maximum of 0.52 mg/$m^3$, the minimum of 0.25 mg/$m^3$, and the average of 0.32 mg/$m^3$ in case of the ventilation system off. Those were higher than the standard value 0.15 mg/$m^3$. In case of the ventilation system on, the floating dust(PM10) was the maximum of 0.174 mg/$m^3$ , the minimum of 0.048 mg/$m^3$, and the average of 0.078 mg/$m^3$. These were the lower than 0.15 mg/$m^3$, the standard of the enforcement regulations of School Sanitation Code in Ministry of Education & Human Resources Development. 5)The concentrations of $CO_2$ and PM10 were largely depending on the number of students and the ventilation system, The installation of the ventilation system is necessary for the amenity environment and the management of the indoor air quality.

• Journal of Convergence for Information Technology
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• v.9 no.12
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• pp.30-38
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• 2019

The purpose of this study is to analyze the level of competitiveness of semiconductor design firms of Korea. The categories of competitiveness are divided into product development, accumulated technology, market-related competencies, human resources, and management system. The sample of 73 semiconductor design companies were used, and the analysis data were gathered by parallel with the questionnaire and the surveyor visited. For respondents, importance of competitiveness factor was prioritized using nominal scale and the competitiveness of each item is expressed based on 100 points. It was confirmed that there was a difference between the order of importance and the actual level of core competence. The ranking of the importance of core competencies is in the order of product development, technical capability, market-related competencies, human resources, and management system. However, in terms of actual competitiveness in each category, human resources were the best, followed by the management level. The product development and technology competencies were in order. The market-related competitiveness was found to be the most urgently raised. In order to increase the market related competitiveness, a new customer base must be developed and the information acquisition capability of the customer, and the ability to analyze their data needs to be improved.

• Korean Journal of Plant Resources
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• v.33 no.5
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• pp.428-435
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• 2020

In this study, we evaluated the inhibitory effect against cell growth and potential molecular mechanism of 100% ethanol extracts of branch from Sageretia thea in human colorectal cancer cells, HCT116. Ethanol dose-dependently extracts of STB significantly suppressed the growth of HCT116 cells through apoptosis. STB activated NF-κB signaling pathway through IκB-α proteasomal degradation and inducing p65 accumulation in nucleus. The inhibition of GSK3β by LiCl didn't affect STB mediated degradation IκB-α but STB mediated p65 accumulation in nucleus. In addition, STB phosphorylated GSK3β. Based on these findings, STB may be a potential candidate for the development of anti-cancer agents for human colorectal cancer.

• Journal of Korea Water Resources Association
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• v.33 no.4
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• pp.447-459
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• 2000

Since the development of water resources is getting more difficult than ever before because of human-sociological condition, it would be necessary to develop a practically applicable technique for the management of water resources based on demand-side concept that could reduce unusable release for more effective and appropriate allocation of limited water resources. The objective of the study is to develop an optimal reservoir system operation model for water supply and energy augmentation by the combination of water budget analysis method in downstream area by MIP technique. The applicable study of the developed model was carried out and water supply capability of Nakdong river basin was re-evaluated by the developed model. The model has been found successful to guarantee appropriate water supply to the basin by means of deficit-supply management method and also turned out to be more practical tool for an optimal reservoir system operation model than other existing models.

• Journal of Engineering Education Research
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• v.15 no.4
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• pp.14-20
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• 2012

The Regional Cooperative Development Center (RCDC) at Tokushima Bunri University was established in 2005. The role of the RCDC is to make a social contribution and to assist in the development of human resources. The RCDC has made contributions to society by organizing meetings to facilitate the exchange of technology, holding public lectures, supporting joint research projects, providing technical assistance for manufacturers, making available the free use of equipment owned by the university and so on. Additionally, the RCDC has put much effort into giving undergraduate students internship opportunities at industries in the eastern part of Kagawa Prefecture (the TOSAN area) in Japan. The RCDC also trained a contracted researcher from a small company about the creation of intellectual property, including how to conduct a patent prior art search, how to prepare a patent specification, etc. The RCDC has worked in partnership with industry, Sanuki City Society of Commerce and Industry and Higashi-Kagawa City Society of Commerce and Industry in order to revitalize local communities.

• Journal of Radiation Industry
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• v.11 no.1
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• pp.33-38
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• 2017

RI-Biomics technology is advanced convergence technologies that can be measured in real time and track in vivo behavior and metabolism of substances using characteristics of the radioactive isotope. Its application fields are increasing such as drug development, agriculture, development of new materials and their utilization, etc. In addition, according to domestic and international developments and changes in the RI-Biomics environment, RI-Biomics professionals are needed to train continuously. To develop systematic human resources basement and competency-based curriculum, we perform competency modeling of pedagogical perspective to targeted at high-performance on RI-Biomics. Furthermore, we redefine the competency model and verified by industry experts with focus group interviews. In the result, two general competencies and three professional competencies were extracted by interview. Each competencies are organized six sub-competencies and nine sub-competencies. In the finial steps, the same procedures were repeated to obtain the consensus of experts on derived competencies and behavioral objectives. The results of the study are applicable to enhance human resource management and to develop the curriculum for RI-Biomics expert training. It is expected to be used as reference material of long term-planning for RI-Biomics professional.