• Proceedings of the KSPS conference
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• 2006.05a
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• pp.135-138
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• 2006

The communication method between human and robot is one of the important parts for a human-robot interaction. And speech is easy and intuitive communication method for human-being. By using speech as a communication method for robot, we can use robot as familiar way. In this paper, we developed TTS for human-robot interaction. Synthesis algorithms were modified for an efficient utilization of restricted resource in robot. And synthesis database were reconstructed for an efficiency. As a result, we could reduce the computation time with slight degradation of the speech quality.

• Biomolecules & Therapeutics
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• v.19 no.2
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• pp.155-173
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• 2011

Humans have and hold 100 trillion intestinal bacteria that are essential for health. For millions of years human-microorganisms interaction has co-evolved, and maintained close symbiotic relationship. Gut bacteria contributes to human health and metabolism, and humans provides the optimum nutrition-rich environment for bacteria. What is the mechanism of the host distinguishing the intestinal bacteria as its cohabiting partner and what kind of benefits does the gut microbiota provide the human are the fundamental questions to be asked and solved in order to make human life a higher quality. This review explains the physiological relationship and mutualism between the host and gut microorganism, and highlights the potential therapeutic approach for treating diseases, maintaining and improving health based on these correlations.

• Journal of the Korea Safety Management & Science
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• v.10 no.1
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• pp.83-90
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• 2008

Development of human-system interfaces (HSI) supporting the interaction between human and automation-based systems, particularly safety-critical sociotechnial systems, entails a wide range of design and evaluation problems. To help HSI designers deal with these problems, many methodologies from traditional human-computer interaction, software engineering, and systems engineering have been applied; however, they have been proved inadequate to develop cognitively well engineered HSI. This paper takes a viewpoint that HSI development is itself a cognitive process consisting of various decision making and problem solving activities and then proposes a design requirements-driven process for developing HSI. High-level design problems and their corresponding design requirements for visual information display are explained to clarify the concept of design requirements. Lastly, conceptual design of software system to support the requirements-driven process and designers' knowledge management is described.

• Fashion & Textile Research Journal
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• v.24 no.2
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• pp.229-240
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• 2022

This study explores the effect of anthropomorphism on fashion chatbot reliability, mediated by perceived intelligence and cognitive evaluation. The moderating effects of individuals' need for human interaction between chatbot anthropomorphism and perceived intelligence, cognitive evaluation, and chatbot reliability are also explored. Participants, who were recruited through the online research firm, responded to questions after watching a video clip showing a conversation with a fashion chatbot on a mobile screen. The data were collected through Mturk, a crowdsourcing platform with an online research panel. All responses (N = 212) were analyzed using SPSS 26.0 for the descriptive statistics, frequency analysis, reliability analysis, exploratory factor analysis, and PROCESS procedure. The results demonstrate that chatbot anthropomorphism increases chatbot reliability, and this is mediated by chatbot intelligence. Although chatbot anthropomorphism increases cognitive evaluation, the effect of cognitive evaluation on chatbot reliability is not significant; thereby, the effect of chatbot anthropomorphism on chatbot reliability is not mediated by the cognitive evaluation. The direct effect of anthropomorphism on chatbot reliability is also moderated by individuals' need for human interaction. For participants with a high need for human interaction, chatbot anthropomorphism increases chatbot reliability; however, anthropomorphism does not significantly affect chatbot reliability for participants with a low need for human interaction. The study's findings contribute to expanding the literature on consumers' new technology acceptance by testing the antecedents affecting service reliability.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2009.06a
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• pp.985-986
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• 2009

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.15 no.1
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• pp.1-11
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• 2015

A concept of Deep Level Situation Understanding is proposed to realize human-like natural communication (called casual communication) among multi-agent (e.g., humans and robots/machines), where the deep level situation understanding consists of surface level understanding (such as gesture/posture understanding, facial expression understanding, speech/voice understanding), emotion understanding, intention understanding, and atmosphere understanding by applying customized knowledge of each agent and by taking considerations of thoughtfulness. The proposal aims to reduce burden of humans in humans-robots interaction, so as to realize harmonious communication by excluding unnecessary troubles or misunderstandings among agents, and finally helps to create a peaceful, happy, and prosperous humans-robots society. A simulated experiment is carried out to validate the deep level situation understanding system on a scenario where meeting-room reservation is done between a human employee and a secretary-robot. The proposed deep level situation understanding system aims to be applied in service robot systems for smoothing the communication and avoiding misunderstanding among agents.

• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2317-2325
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• 2014

P-glycoprotein (P-gp) is a member of the ATP-Binding Cassette transporter superfamily and mediates transmembrane efflux of many drugs. Since it is involved in multi-drug resistance activity in various cancer cells, the development of P-gp inhibitor is one of the major concerns in anticancer therapy. Human P-gp protein has at least two "functional" drug binding sites that are called "H" site and "R" site, hence it has multi-binding-specificities. Though the amino acid residues that constitute in drug binding pockets have been proposed by previous experimental evidences, the shapes and the binding poses are not revealed clearly yet. In this study, human P-gp structure was built by homology modeling with available crystal structure of mouse P-gp as a template and docking simulations were performed with inhibitors such as verapamil, hoechst33342, and rhodamine123 to construct the interaction between human P-gp and its inhibitors. The docking simulations were performed 500 times for each inhibitor, and then the interaction frequency of the amino acids at the binding poses was analyzed. With the analysis results, we proposed highly contributing residues that constitute binding pockets of the human P-gp for the inhibitors. Using the highly contributing residues, we proposed the locations and the shapes of verapamil binding site and "R" site, and suggested the possible position of "H" site.

• Journal of KIISE:Software and Applications
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• v.35 no.5
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• pp.297-305
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• 2008

We present a cleaning robot algorithm that can be implemented on low-cost robot architecture while the cleaning performance far exceeds the conventional random style cleaning through human-robot interaction. We clarify the advantages and disadvantages of the two notable cleaning robot styles: the random and the mapping styles, and show the possibility how we can achieve the performance of the complicated mapping style under the random style-like robot architecture using the idea of human-aided cleaning algorithm. Experimental results are presented to show the performance.

• Journal of Pharmaceutical Investigation
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• v.36 no.4
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• pp.283-286
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• 2006

The present study aimed to investigate the interaction of nucleoside analogs with human organic anion transporter 1 and 3(hOAT1 and hOAT3) that play a primary role in the tubular uptake of endogenous and exogenous organic anions in the kidney. The interactions of ddC, ara-C, ara-A and ara-U with hOAT1 and hOAT3 were examined using MDCK cells stably overexpressing hOAT1 or hOAT3. Among the tested drugs, ddC showed the highest affinity to hOAT1 with $IC_{50}$ values of 5.2 mM, while ara-A, ara-C and ara-U weakly inhibited the cellular uptake of $[^3H]-PAH$ in MDCK-hOAT1 cells at 1 mM. In contrast, all the tested drugs did not have any inhibition effect on the cellular uptake of $[^3H]-estrone$ sulfate in MDCK-hOAT3 cells over the drug concentration of 0.01-2 mM, implying that they might not interact with hOAT3. Taken all together, the present study suggests that hOAT1 could weakly interact with nucleoside analogues such as ddC, ara-C, ara-A and ara-U but the interaction with hOAT3 during the urinary excretion of these nucleoside analogues may be negligible in the kidney.

• Journal of the HCI Society of Korea
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• v.12 no.3
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• pp.5-11
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• 2017

Korean traditional dance has cultural value and is human's cultural heritage. But they are in danger which is caused by lack of bearers and public interest. E-Learning of traditional dance using network technology and digital media can be a solution to extinction problem. The aim of this study is to propose the E-Learning courses and systems for learning traditional dance. E-Learning systems were evaluated in accordance with the HCI (Human Computer Interaction) user evaluation. This study contribute to overcoming distance constraints by offering synchronous E-Learning education system of traditional dance as intangible cultural heritage through new media experience.