• Title/Summary/Keyword: GCT

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A Study on the Immune Modulation and Hepatoprotection of Gamichunggan-tang (GCT) (가미청간탕의 간보호 및 면역조절효과)

  • 손창규;한성수;조종관
    • The Journal of Korean Medicine
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    • v.23 no.2
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    • pp.28-38
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    • 2002
  • Objectives : This study was to examine the efficacy of GCT on the hepatoprotective effect in the liver function and immune octivity. Methods : The experiment to investigate the hepatoprotective effect of GCT on the liver damage was conducted with D-galactosamine. The experiments to verify the effects of GCT on the immune activity were conducted by carbon clearance assay, plaque-forming cell SRBC assay of IgM, lymphoproliferation assay of T and B cells, and adherence and phagocytosis of mocrophages. Results: In the damage of liver induced by D-galactosamine, GCT carried hepatoprotective effect on AST. In carbon clearance assay GCT showed significant effect on phagocytosis of Kuffer cells. In the plaque-forming cell assay, GCT improved the formation of IgM. In the lymphoproliferation assay, GCT activated the formation of T and B lymphocytes. In macrophages, GCT activated adherence and phagocytosis. Conclusion : Though further study is needed, our findings suggest that GCT could be recommended as hepatoprotector and immune modulator for liver disease.

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Process and Structure Design for High Power Reverse-Conducting Gate Commutated Thyristors (RC- GCTs) (고전압 역도통 Gate Commutated Thyristor (RC-GCT) 소자의 공정 및 구조 설계)

  • Kim, Sang-Cheol;Kim, Eun-Dong;Zhang, Chang-Li;Kim, Nam-Kyun;Baek, Do-Hyun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.07a
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    • pp.1096-1099
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    • 2001
  • The basic design structure of RC-GCTs (Reserve-Conducting Gate-Commutated Thyristors) is firstly given in this paper. The bulk of wafer is punch-through (PT) type with high resistivity and narrow N-base width. The photo-mask was designed upon the turn-off characteristics of GCT and solution of separation between GCT and diode part. The center part of Si wafer is free-wheeling diode (FWD) and outer is GCT part which has 240 fingers totally. The switching performance of GCT was investigated by Dessis of ISE. The basic manufacture process of 2500V-4500V RC-GCTs was given in this work. Additionally, the local carrier lifetime control by 5Mev proton irradiation was adopted so as to not only to have the softness of reverse recovering for FWD but for reduction of turn-off losses of GCT as well.

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Smooth Auricular Cutaneous Granular Cell Tumor Mimics Epidermoid Cyst

  • Choi, Jeong Hwan
    • Journal of Audiology & Otology
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    • v.24 no.2
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    • pp.103-106
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    • 2020
  • Granular cell tumor (GCT) is a rare, benign neoplasm of Schwann cell origin. GCT is composed of cells with eosinophilic granular cytoplasm. GCT presents as a solitary painless nodule. Because of their subtle clinical presentation, GCTs are often misdiagnosed. This report of a 47-year-old woman with an auricular GCT serves to highlight that complete excision and histopathological evaluation should be attempted even in apparently benign cases, to ensure complete cure.

Smooth Auricular Cutaneous Granular Cell Tumor Mimics Epidermoid Cyst

  • Choi, Jeong Hwan
    • Korean Journal of Audiology
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    • v.24 no.2
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    • pp.103-106
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    • 2020
  • Granular cell tumor (GCT) is a rare, benign neoplasm of Schwann cell origin. GCT is composed of cells with eosinophilic granular cytoplasm. GCT presents as a solitary painless nodule. Because of their subtle clinical presentation, GCTs are often misdiagnosed. This report of a 47-year-old woman with an auricular GCT serves to highlight that complete excision and histopathological evaluation should be attempted even in apparently benign cases, to ensure complete cure.

Design Consideration for Structure of 2500-4500V RC-GCT

  • Kim E. D.;Kim S. C.;Zhang C. L.;Kim N. K.;Bai J. B.;Li J. H.;Lu J. Q.
    • Proceedings of the KIPE Conference
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    • 2001.10a
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    • pp.36-38
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    • 2001
  • A basic structure of 2500V-4500V reverse-conducting GCT (RC-GCT) is given in this paper. The punch-through type (PT) is adopted for narrow N-base with high resistivity so that the fast turn-off and low on-state voltage can be achieved. The photo mask design was made upon the both turn-off performance and solution of separation between GCT and integrated freewheeling diode (FWD) part. The turn-on and turn-off characteristics for reserve-conducting gate commutated thyristors (RC-GCTs) were investigated by ISE simulation. Additionally, the local carrier lifetime control by proton irradiation was adopted so as not only to obtain the reduction of turn-off losses of GCT but also to reach a soft reverse recovering characteristics of FWD

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Design of 4.5kV/1.5kA IGCT (4.5kV/1.5kA급 IGCT 설계 및 특성분석)

  • Kim, Hyoung-Woo;Kim, Sang-Cheol;Seo, Kil-Su;Kim, Eun-Dong
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.07a
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    • pp.357-360
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    • 2003
  • In this paper, we designed 4.5kV/1.5kA IGCT devices. GCT thyristor has many superior characteristics compared with GTO thyristor, for examples; snubberless turn-off capability, short storage time, high turn-on capability, small turn-off gate charge and low total power loss of the application system containing device and peripheral parts such as anode reactor and snubber capacitance. In this paper we designed GCT thyristor devices, and analyzed static and dynamic characteristics of GCT thyristor depending on the minority carrier lifetime, n-base thickness and doping concentration of n-base region, respectively. Especially, turn-on and turn-off characteristics are very important characteristics for GCT thyristor devices. So, we considered above characteristic for design and analysis of GCT devices.

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Intracranial Germ Cell Tumor in the Molecular Era

  • Phi, Ji Hoon;Wang, Kyu-Chang;Kim, Seung-Ki
    • Journal of Korean Neurosurgical Society
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    • v.61 no.3
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    • pp.333-342
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    • 2018
  • Intracranial germ cell tumors (iGCTs) are a heterogeneous group of tumors with peculiar characteristics clearly distinguished from other brain tumors of neuroepithelial origin. Diverse histology, similarity to gonadal GCT, predilection to one sex, and geographic difference in incidence all present enigmas and fascinating challenges. The treatment of iGCT has advanced for germinoma to date; thus, clinical attention has shifted from survival to long-term quality of life. However, for non-germinomatous GCT, current protocols provide only modest improvement and more innovative therapies are needed. Recently, next-generation sequencing studies have revealed the genomic landscape of iGCT. Novel mutations in the KIT-RAS-MAPK and AKT-MTOR pathways were identified. More importantly, methylation profiling revealed a new method to assess the pathogenesis of iGCT. Molecular research will unleash new knowledge on the origin of iGCT and solve the many mysteries that have lingered on this peculiar neoplasm for a long time.

Generating Test Data for Programs with Flag Variables using Goal-oriented Concolic Testing (목적 지향 콘콜릭 테스팅을 이용한 플래그 변수가 있는 프로그램에 대한 테스트 데이터 생성)

  • Chung, In-Sang
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.12 no.1
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    • pp.123-132
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    • 2012
  • This paper presents a goal-oriented test data generation technique that specializes concolic testing. The proposed technique, referred to as GCT (Goal-oriented Concolic Testing) produces test inputs which execute a specific target. Concolic testing can be seen as the brute force approach to search the space of all possible paths until a required test input is found. In contrast, GCT restricts the number of program paths that are explored by using data flow information to identify statements that should be executed beforehand in order for the target to be executed. We conducted experiments to evaluate the performance of GCT with programs with flag variables to show its effectiveness.

Developing a Standard Costing Model for a Container Terminal - A Case Study for to PECT and GCT - (컨테이너부두의 표준원가모델 구축)

  • 임종길;한국해상교통정책연구소연구위원
    • Journal of Korean Port Research
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    • v.13 no.2
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    • pp.279-288
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    • 1999
  • This paper is concerned with developing a standard costing model based on the case study of PECT and GCT in order to improve operation efficiency and design business strategy. In doing so the model can be a useful tool to analyze current calculation system of lease charge at the two terminals and to judge whether the level of lease charge currently applied to them is justifiable for thier profitability.

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Giant Cell Tumor of Upper Thoracic Spine

  • Lee, Chul Gab;Kim, Sung Hoon;Kim, Dong Min;Kim, Seok Won
    • Journal of Korean Neurosurgical Society
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    • v.55 no.3
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    • pp.167-169
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    • 2014
  • Giant cell tumor (GCT) of the spine is a rare benign tumor, but can be aggressive and can exhibit a high local recurrence rate. Furthermore, GCT of the upper thoracic spine may pose diagnostic and management difficulties. Here, we report a rare case of GCT of the upper thoracic spine with soft tissue extension to the spinal canal. The patient was managed by decompressive laminectomy and posterolateral fusion followed by an injection of polymethylmethacrylate into the vertebral lesion. The patient recovered clinically and showed radiological improvement after surgical treatment without tumor recurrence at his last follow-up of postoperative 7 years. We present this unusual case of GCT and include a review of the literature.