DOI QR코드

DOI QR Code

Giant Cell Tumor of Upper Thoracic Spine

  • Lee, Chul Gab (Department of Environmental Medicine, School of Medicine, Chosun University) ;
  • Kim, Sung Hoon (Department of Rehabilitation Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine) ;
  • Kim, Dong Min (Department of Internal Medicine, School of Medicine, Chosun University) ;
  • Kim, Seok Won (Department of Neurosurgery, School of Medicine, Chosun University)
  • Received : 2013.06.14
  • Accepted : 2014.02.28
  • Published : 2014.03.28

Abstract

Giant cell tumor (GCT) of the spine is a rare benign tumor, but can be aggressive and can exhibit a high local recurrence rate. Furthermore, GCT of the upper thoracic spine may pose diagnostic and management difficulties. Here, we report a rare case of GCT of the upper thoracic spine with soft tissue extension to the spinal canal. The patient was managed by decompressive laminectomy and posterolateral fusion followed by an injection of polymethylmethacrylate into the vertebral lesion. The patient recovered clinically and showed radiological improvement after surgical treatment without tumor recurrence at his last follow-up of postoperative 7 years. We present this unusual case of GCT and include a review of the literature.

Keywords

References

  1. Bertoni F, Bacchini P, Staals EL : Malignancy in giant cell tumor of bone. Cancer 97 : 2520-2529, 2003 https://doi.org/10.1002/cncr.11359
  2. Bidwell JK, Young JW, Khalluff E : Giant cell tumor of the spine : computed tomography appearance and review of the literature. J Comput Tomogr 11 : 307-311, 1987 https://doi.org/10.1016/0149-936X(87)90104-4
  3. Hart RA, Boriani S, Biagini R, Currier B, Weinstein JN : A system for surgical staging and management of spine tumors. A clinical outcome study of giant cell tumors of the spine. Spine (Phila Pa 1976) 22 : 1773-1782; discussion 1783, 1997 https://doi.org/10.1097/00007632-199708010-00018
  4. Hwang GJ, Kim KN, Yoon DH, Yang WI : Total spondylectomy for giant cell tumor of cervical spine. J Korean Neurosurg Soc 34 : 262-264, 2003
  5. Larsson SE, Lorentzon R, Boquist L : Giant-cell tumors of the spine and sacrum causing neurological symptoms. Clin Orthop Relat Res (111) : 201-211, 1975
  6. Paúl L, Santonja C, Izquierdo E : Complete necrosis of a spinal giant cell tumor after vertebroplasty. J Vasc Interv Radiol 17 : 727-731, 2006 https://doi.org/10.1097/01.RVI.0000202646.96112.30
  7. Sanjay BK, Sim FH, Unni KK, McLeod RA, Klassen RA : Giant-cell tumours of the spine. J Bone Joint Surg Br 75 : 148-154, 1993
  8. Weill A, Chiras J, Simon JM, Rose M, Sola-Martinez T, Enkaoua E : Spinal metastases : indications for and results of percutaneous injection of acrylic surgical cement. Radiology 199 : 241-247, 1996 https://doi.org/10.1148/radiology.199.1.8633152
  9. Yan SC, Xu QM, Lin JR : Diagnosis and treatment of giant cell tumor in the thoracic spine. J Surg Oncol 40 : 128-131, 1989 https://doi.org/10.1002/jso.2930400213
  10. Zhen W, Yaotian H, Songjian L, Ge L, Qingliang W : Giant-cell tumour of bone. The long-term results of treatment by curettage and bone graft. J Bone Joint Surg Br 86 : 212-216, 2004 https://doi.org/10.1302/0301-620X.86B2.14362

Cited by

  1. Clinical Outcome of Treatment for Patients with Giant Cell Tumor in Spine vol.58, pp.3, 2014, https://doi.org/10.3340/jkns.2015.58.3.248
  2. Systematic Review and Meta-analysis of En Bloc Vertebrectomy Compared with Intralesional Resection for Giant Cell Tumors of the Mobile Spine vol.6, pp.8, 2014, https://doi.org/10.1055/s-0036-1579746
  3. Bone Cement-Augmented Percutaneous Screw Fixation for Malignant Spinal Metastases : Is It Feasible? vol.60, pp.2, 2014, https://doi.org/10.3340/jkns.2016.0909.003
  4. Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report vol.12, pp.1, 2014, https://doi.org/10.1159/000497379