• Applied Chemistry for Engineering
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• v.20 no.6
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• pp.632-637
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• 2009

Poly(${\varepsilon}-caprolacton$)/ethyl cellulose (PCL/EC) microcapsules containing pluronic F127 were prepared by a spray drying method. The aqueous phase, 20% of pluronic F127 was dissolved in distilled water, and the organic phase, 5% of PCL and EC were dissolved in dichloromethane. The microcapsules were obtained by spray drying the water-in-oil (W/O) emulsion. According to the data of scanning electron microscopy and particle analyzer, tens of micro size microcapsules were observed. On a differential scanning calorimeter, the phase transition temperatures of microcapsules were observed and they were found around those of pluronic F127 and poly(${\varepsilon}-caprolacton$), which were the main components of the microcapsules. At the range of $30{\sim}45^{\circ}C$, temperature-dependent release properties were investigated using fluorescein isothicyanate-dextran (FITC-dextran) and blue dextran as a model drug. When the temperature was increased, the degree of release of microcapsule was also increased. FITC-dextran, the relative low molecular weight, was more released than blue-dextran.

• Journal of the Chungcheong Mathematical Society
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• v.28 no.1
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• pp.127-138
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• 2015

In this paper, we introduce the notion of f-derivation in a BE-algebra, and consider the properties of f-derivations. Also, we characterize the fixed set $Fix_d(X)$ and Kerd by f-derivations. Moreover, we prove that if d is a f-derivation of a BE-algebra, every f-filter F is a a d-invariant.

• Journal of the Chungcheong Mathematical Society
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• v.32 no.1
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• pp.127-138
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• 2019

In this paper, I investigate a stability of the following set-valued functional equation $$f(x+3y){\oplus}10f(x+y){\oplus}7f(-x){\oplus}5f(x-y)=5f(x+2y){\oplus}f(x){\oplus}f(2x){\oplus}f(x-2y)$$ in the sense of P. $G{\check{a}}vruta$.

• Journal of Pharmaceutical Investigation
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• v.31 no.1
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• pp.1-5
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• 2001

The aggregation behavior of nystatin (NYS) in the presence of pluronic F127, triblock copolymer of poly (ethylene oxide) (PEO) and poly (propylene oxide) (PPO), was measured and correlated with hemolytic activity. Antifungal activity was also studied using Saccharomyces cerevisiae as a model strain. The critical aggregation concentrations (CAC) of the drug were 50.1, 108.0, 134.2, 154.3, and $217.9\;{\mu}M$ at 0.1%, 0.5%, 1.0%, 1.5%, and 2.0% pluronic F127 solution, respectively. The levels of NYS required to start lysis of erythrocytes were about 80, 100, 125, 150, and $200\;{\mu}M$ at 0.1%, 0.5%, 1.0%, 1.5%, and 2.0% pluronic F127 solution, respectively. It was $50\;{\mu}M$ in the absence of the polymer. Minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) of NYS-pluronic F127 lyophilizate were same at $3\;{\mu}g/ml$, while MIC and MFC of pure NYS are $3\;{\mu}g/ml$ and $12\;{\mu}g/ml$, respectively. By modulating the aggregation behavior of NYS, pluronic F127 was able to reduce the toxicity of the drug without compromising the MIC and MFC.

• Journal of Pharmaceutical Investigation
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• v.20 no.3
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• pp.121-127
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• 1990

Mefenamic acid has been widely used clinically as an anti-inflammatory analgesic. It has poor solubility in water $(41\;{\mu}g/ml)$ and there is the difficulty of dissolution in the mefenamic acid capsules. A study was made to investigate the effect of various surfactants on the dissolution of mefenamic acid capsules. The surfactants used were sodium lauryl sulfate (SLS), Pluronic F-68, F-77, and F-127. Mefenamic acid capsule containing surfactant showed significantly improved dissolution characteristics. The dissolution rate was fast in the order of SLS > F-77 > F-68 > F-127 in mefenamic acid capsules containing 0.2 w/w % surfactant. SLS was selected for further study on the bioavailability in rabbits. The area under the plasma concentration-time curve $(AUC_{0-24})$ of mefenamic acid capsule containing SLS was higher than one of mefenamic acid capsule not containing surfactant.

• Communications of the Korean Mathematical Society
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• v.24 no.1
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• pp.127-144
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• 2009

Let f be a diffeomorphism of a compact $C^{\infty}$ manifold, and let p be a hyperbolic periodic point of f. In this paper we introduce the notion of $C^1$-stable inverse shadowing for a closed f-invariant set, and prove that (i) the chain recurrent set $\cal{R}(f)$ of f has $C^1$-stable inverse shadowing property if and only if f satisfies both Axiom A and no-cycle condition, (ii) $C^1$-generically, the chain component $C_f(p)$ of f associated to p is hyperbolic if and only if $C_f(p)$ has the $C^1$-stable inverse shadowing property.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.34 no.6
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• pp.384-390
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• 2012

Purpose: The purpose of this study is to examine in vivo osteogenesis of cultured human periosteal-derived cells and polydioxanone/pluronic F127 scaffold. Methods: Two one-year-old miniature pigs were used in this study. $2{\times}10^6$ periosteal-derived cells in 1 mL medium were seeded by dropping the cell suspension into the polydioxanone/pluronic F127 scaffold. These cell-scaffold constructs were cultured in osteogenic Dulbecco's modified Eagle's medium for 7 days. Under general anesthesia with azaperone and tiletamine-zolazepam, the mandibular body and ramus of the pigs were exposed. Three bony defects were created. Polydioxanone/pluronic F127 scaffold with periosteal-derived cells and the scaffold only were implanted into each defect. Another defect was left empty. Twelve weeks after implantation, the animals were sacrificed. Results: New bone formation was clearly observed in the polydioxanone/pluronic F127 scaffold with periosteal-derived cells. Newly generated bone was also observed in the scaffold without periosteal-derived osteoblasts and empty defect, but was mostly limited to the periphery. Conclusion: These results suggest that cultured human periosteal-derived cells have good osteogenic capacity in a polydioxanone/pluronic F127 scaffold, which provides a proper environment for the osteoblastic differentiation of these cells.

• Applied Chemistry for Engineering
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• v.32 no.2
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• pp.219-223
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• 2021

Considering the current COVID 19 pandemic, herein, we developed a material that can be used to fabricate a device for checking the body temperature of a person who has been exposed to influenza or corona virus. This material was formed by mixing pluronic F127 (F127) with a polydiacetylene (PDA) vesicle, which was formed with 10,12-pentacosadiynoic acid. The color of the system started to change from blue to light purple at 37 ℃, finally turning reddish at 40 ℃. Thus, the developed material can be used to detect changes in body temperature, and thus, detect signs of fever. The mixing ratio of the PDA vesicle and F127 was an important factor for controlling the temperature at which the color change started. The results showed that the color change accompanied by the separation of the PDA vesicle with F127. We believe that this phenomenon plays an important role in reducing the conjugation length in the double and triple bond of PDA.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.27 no.2
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• pp.107-110
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• 1982

Two strains of branched wheat introduced from CIMMYT were crossed with two varieties of normal headed common wheat (Triticum aestivum L.). The number of genes conditioning branching trait in the two strains was determined from the studies of $F_1$ and $F_2$ populations under longday and shortday conditions. Branching strains PH 119 appeared to have three recessive genes and PH 127 two receive genes. The segregating ratio of branching vs normal was unaffected by the different photoperods but the expression of branching trait was little more vigorous under the shortday condition. Both PH 119 and PH 127 had a single dominant gene for glume pubescence. Association between branching trait and glume pubescence was determined with the $X^2$ -test for independence. Glume pubescence was not associated with branching in PH119 $\times$ Chugoku 81 but was associated in PH119 $\times$ Olmil (p < 0.05).

• Journal of Convergence for Information Technology
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• v.8 no.3
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• pp.127-136
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• 2018

This study was to identify factors influencing satisfaction on clinical practice of dental hygienist students located in G, J region. The data was analyzed by t-test, Anova, Pearson correlation coefficient, and multiple regression using SPSS 21.0 program. There were significant in satisfaction of score(F=2.925, p<.05), perceive heath status(F=8.108, p<.001), satisfaction on department(F=8.198, p<.001). The relationship on peers with score(r=.277, p=.01) and perceive health status correlations with relationships on peers(r=.327, p=.01), The satisfaction on clinical practice had positive correlations with score(r=.127, p=.05), perceive health status(r=.226, p=.01), relationship on peers(r=.240, p=.01). The factors influencing satisfaction on clinical practice were satisfaction of relationship on peers, satisfaction of department, perceive health status. The results suggest that development of program to improve satisfaction on clinical practice of dental hygiene students.