• Journal of Sasang Constitutional Medicine
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• v.30 no.1
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• pp.32-42
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• 2018

The purpose of this study aimed to know the association between seven health practices and self rated health by Sasang constitution. We recruited 367 subjects aged from 30 to 59. KS 15 questionnaire was used to classify Sasang constitution and visual analogue scale was used to estimate self rated health. Chi-square test was used to know the difference of occupation distribution by Sasang constitution. Anova test, T-test and Chi-square test also used to analyze the difference of self rated health between the health practice group and non-health group in individual Sasang constitution. SPSS 21.0K was used and significant p was <.05. Regular morning meal, non-snaking, good sleeping and sufficient exercise had higher self rated health score (p<.05). Regular morning meal, good sleeping and sufficient exercise had higher score in Tae-eumin (p<.05). Good sleeping had higher self rated health score in Soeumin and Soyangin (p<.05). These results suggest there is possibility that health practices for health promotion could be different according to Sasang constitution.

• The Journal of Korean Medicine
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• v.30 no.4
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• pp.142-161
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• 2009

Objectives: There are many unknowns surrounding Jeong-Jo's death. To better understand Jeong-Jo's death, we closely inspected his medical records from the 20 days before his death in The Annals of the Chosun Dynasty (朝鮮王朝實錄) and Seungjeongwon Ilgi (承政院日記), Understanding medical treatment before death, we can correctly trace the cause of Jeong-Jo's death. Methods: According to The Annals of the Chosun Dynasty (朝鮮王朝實錄) and Seungjeongwon Ilgi (承政院日記), we examined his medical records between June 14 and June 28 of 1800, as to the change in chief complaint, cold and heat, thirst, syndrome differentiation, the opinions of Jeong-Jo, and the opinions of doctors, The original work, The Annals of the Chosun Dynasty and Seungjeongwon Ilgi were provided by NIKH (The National Institute of Korean History). The Korean translation of The Annals of the Chosun Dynasty was also provided by NIKH. Seungjeongwon Ilgi (original work written in Chinese characters) was directly translated into Korean by the study author. Results: 1. Jeong-Jo's is likely to have died of septicemia caused by an abscess on his back. 2. The cause of Jeong-Jo's death could be stroke due to hypertension, mental stress, and 'Wha (火) disease' Conclusions: The dominant view that Jeong-Jo was murdered by poison is not likely.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.1
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• pp.53-58
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• 2014

The object of this study was to evaluate the single dose toxicity of Choweseuncheng-tang (CWS), a polyherbal formula have been traditionally used as prevention or treatment agent for various diseases as Tae-eumin prescription on Korean medicinal theory, Sasang-euihak, in male and female mice. Aqueous extracts of CWS (yield = 11.00%) was administered to female and male mice as an oral dose of 2,000, 1,000 and 500 mg/kg (body weight) according to the recommendation of Korea Food and Drug Administration (KFDA) Guidelines. Animals were monitored for the mortality and changes in body weight, clinical signs and gross observation during 14 days after dosing, upon necropsy; organ weight and histopathology of 14 principle organs were also examined. As results, we could not find any CWS treatment related mortality and clinical signs, changes in the body and organ weights, gross findings and changes in histopathology of principle organs, except for some dose-independent accidental findings. The results obtained in this study suggest that the 50% lethal dose and approximate lethal dose of CWS aqueous extracts in both female and male mice were considered as over 2,000 mg/kg, the limited highest dosage recommended by KFDA Guidelines, and can be safety used in clinics.

• Journal of Sasang Constitutional Medicine
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• v.22 no.1
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• pp.9-16
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• 2010

1. Background: GalgeunNabokja-Tang(葛根蘿葍子湯) is suggested as treatment and prescription of Exterior Heat syndrome Diarrhea(表熱證泄瀉) in Donguisusebowon Tae-eumin Interior febrile disease induced form the liver affected by heat("東醫壽世保元" "太陰人肝受熱裏熱病論"), but is not recorded the treatment contents in Sinjungbang("新定太陰人病應用要藥二十四方"). 2. Methods: Accordingly, the writer surveyed, compared, and arranged the relevant contents by collecting books of doctors of Four-Constitutional Medicine(四象醫) since Lee Je-ma including Lee Je-ma's books. 3. Results: and Conclusions: 1) The treatment contents in GalgeunNabokja-Tang are thought to be valid to have the criterion as the contents of appearing in SanggyohyuntoDonguisusebowon Boyubang("詳校懸吐東醫壽世保元" "補遺方"). 2) The origin in GalgeunNabokja-Tang is GalgeunNabokja-Tang in Bimang-lok("備忘錄"). And the period of having made treatment for the first time may be estimated to be the one between Donguisuse- bowonSasangchobonguan("東醫壽世保元四象草本卷") and HamsansachonDonguisusebowonGabogubon ("咸山沙村東醫壽世保元甲午舊本"). 3) GalgeunNabokja-Tang is thought to be probably what Han Du-jeong recorded in Boyubang by searching for what Lee Je-ma modified some of GalgeunNabokja-Tang in Bimang-lok while writing Pathological Syndromes("病證論") in Donguisusebowon("東醫壽世保元").

• Journal of Sasang Constitutional Medicine
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• v.20 no.3
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• pp.199-207
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• 2008

1. Objectives Sasang Constitutional Medicine is Mind-Body medicine and it is based on difference of Nature & Emotion(性情) & real purpose(恒心). The purpose of this study is to evaluate the effect of Hyangbujapalmul-tang for somatoform disorders and is to drive the importance of psychiatric approach home. 2. Method The subject is about 49-year-old Soeumin patient presumed by Undifferentiated somatoform disorder based on his nature & emotion, physical characteristics, symptoms, and we have prescribed Soeumin Hyangsayangyui-tang, Ceongunggyegi-tang, Hyangbujapalmul-tang. Soeumin Hyangsayangyui-tang was prescribed based on oridinary symptoms(素症), Soeumin Ceongunggyegi-tang was prescribed based on real symptoms(病症), Soeumin Hyangsayangyui-tang was prescribed based on Nature & Emotion(性情) & real purpose(恒心). 3. Result and conclusions In result, Hyangbujapalmul-tang based on Nature & Emotion(性情) & real purpose(恒心) showed best positive response. It is necessary to approach to somatoform disorders not only in clinical view but also in psychiatric view based on Nature & Emotion(性情) & real purpose(恒心)

• Journal of Sasang Constitutional Medicine
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• v.18 no.1
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• pp.75-90
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• 2006

1. Objectives The Sasang Constitution has been studied in many parts and one of the most common inquiries is the self-reporting questionnaire. But the established investigation has the problem that the respondents are not fully aware of the questionnaires and answer them. To settle this problem, it's been made new questionnaires through two steps. 2. Methods At first step, the testers ate classified into Yangin(陽人) and Eumin(陰人). And then, Taeyangin is distinguished from Soyangin likewise Taeumin is told from Soeumin. It's called 'The Two Step Questionnaire for the Sasang Constitution Diagnosis(TS-QSCD)'. This new method is tested by 160 testers and Woosuk university students whose constitution ate confirmed to make clear clinical uses 3. Results and Conclusions Questionnaire Sasang Constitution corresponds with The Real Sasang Constitution at the rate of 71.87%. Only 5.63% has shown an error at the first step. Every experimenters by constitutions, the 56 objects of 74 Taeumin are confirmed the same as it is. It has 84.85% accuracy. The 27 objects of 32 Soeumin come to the same thing and it has 69.23% accuracy. Similarly, the 32 objects of 42 Soyangin come to the same conclusion and 72.73% accuracy high As the result, in comparison to the Real Constitution with the Constitution by questionnaires, the accord comes out Kappa Indices 0.6427866. This result is comparatively high. Chi-square Test can be shown statistical meaning as well.

• Journal of Sasang Constitutional Medicine
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• v.24 no.4
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• pp.75-83
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• 2012

Objectives : Although Yeoldahanso-tang (YDHST) has been widely used for treatment of obesity and its related diseases such as hyperinsulinemia and hypertension for Taeeumin, no scientific evidence has reported yet to support its ability to work against these metabolic disorders. Our study was aimed to investigate the anti-obesity effect of YDHST extract on the cellular differentiation of 3T3-L1 preadipocytes into adipocytes. Methods : 3T3-L1 preadipocytes were differentiated into adipocytes by adding insulin, dexamethasone and 3-isobutyl-1-methylxanthine (IBMX) for 8 days in the absence or presence of YDHST extract. Anti-obesity effects of YDHST extract were evaluated by Oil Red O staining, glycerol-3-phosphate dehydrogenase (GPDH) activity, triglyceride contents, and leptin production. Results : YDHST extract remarkably prevented lipid accumulation with no cytotoxicity in the differentiated 3T3-L1 cells. In addition, YDHST extract decreased contents of triglyceride 3T3-L1 adipocytes. Consistently, YDHST extract caused a significant inhibition of GPDH activity and leptin production in a dose-dependent manner. Conclusions : Our findings suggest that Sasang constitutional herbal formula YDHST for Tae-eumin has anti-obesity activity by regulation of the adipogenesis process in vitro. Additional study will be required to further confirm the inhibitory effect on adipocyte differentiation by using in vivo animal model.

• Korean Journal of Food Science and Technology
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• v.41 no.5
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• pp.572-577
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• 2009

The effects of cereal (rice, brown rice, barley, glutinous rice) ethanol extracts on the proliferation, nitric oxide (NO) production, and level of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) in B and T lymphocytes, isolated from human blood cells of sasang constitution, were examined in vitro. The rice, brown rice, and glutinous rice ethanol extract, which are known as suitable for eumin (taeumin and soeumin) constitutions, showed the highest activities for proliferation, NO production, and TNF-${\alpha}$ concentration, respectively. However, the barley ethanol extract, which is known tobe suitable for yangin (taeyangin and soyangin) constitutions, showed the highest overall activities for proliferation, NO production, and TNF-${\alpha}$ concentration. The different immunological activities of the cereal extracts in sasang constitution lymphocytes might be due to their individual components. Thus, determination of components from the cereal extracts suitable for sasang constitution could be useful in new food developments.

• Journal of Sasang Constitutional Medicine
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• v.21 no.2
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• pp.48-57
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• 2009

1. Objective : The object of this thesis is to find the basis of Constitution assignment of Nogeun(蘆根, Phragmites communis Trin.) used to the medication for Taeyangin. Also, it is to recognize what kind of Constitution of Mogeun(茅根, Imperata cylindrica var. koenigii) is needed to be assigned to. 2. Methods "Dongyi Soose Bowon", 'SinchukBon', 'ChobonKwun', other related Sasang Constitutional Medicine(SCM) books, herbal medicine books such as "Boncho Kangmok", and etc. were compared and researched. 3. Results & Conclusions : 1) Nogeun(蘆根) lowers Qi and harmonizes the body. Because of the effect of lowering soar-Qi(氣), it used to treat the symptoms of Taeyangin's vomiting(噎膈反胃, Stomach reflux due to dysphagia-occlusion). Also Yuksoo Nogeun(逆水蘆恨, Reed growing near the river in low scream) is the basis of considering inhale-gathering Qi effect as a major indication of Nogeun. 2) The theory of classifying White Mogeun as a Tae-eumin Medicinal is based on the effect of Radiating while classifying White Mogeun as a Taeyangin Medicinal is based on the effect of treating stomach reflux(反胃). But both basis are not conclusive and thus requires further study. 3) In "Sasang Geumge Bibang", the first text ever to write only about separate medicinals and Classified Foods (食物類) of each constitution, there were examples of Nogeun and Mogeun's usage based on other pre-existing medical texts. 4) Because White Mogeun is classified as Tae-yangin medication in "Dongmu Yugo", but classified as a Taeeumin's medication in "Dongyi Soose Bowon" 'ChobonKwun' and "Sasang Geumge Bibang", there remains a controversy.

• Journal of Sasang Constitutional Medicine
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• v.21 no.1
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• pp.44-52
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• 2009

1. Objectives Jeong-Jo's death has many mistery. So we understand rightly Jeong-Jo's death. we inspect closely medical records of 20 days before death(in The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書)， GukSoBoGam(國朝寶鑑). We understand medical treatment before death. It is based on Jeong-Jo's Constitution. So we trace the cause of a Jeong-Jo's death rightly. 2. Methods According to The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書) GukSoBoGam(國朝寶鑑). We found out Jeoung-Jo's Sasang constitutional elemet. We point on Jeoung-Jo's nature and emotion, temperament and talent, features and way of speaking, physical appearance, healthy state, ordinary symptom, pathological syndromes and pharmacology. so documentary records was worthy of notice. 3. Results and conclusions 1. Jeong-Jo has prominent cheekbones,flat face. It belong to Tae-eum. 2. Jeong-Jo's physical appearance is mild,around,large. It belong ro Tae-eum. 3. Jeong-Jo's favorite food and herb were belong to Tae-eum interior febrile disease herb. which is Exhale Dispersing Qi 4. So even though Jeoung-Jo is Tae-eum, He had a weak body. It main cause that Smoking, insomnia, heave work, Hwa disease. 5. Jeong-Jo's is Interior febrile disease induced form the liver affected by heat in Tae-eumin