• Preventive Nutrition and Food Science
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• 제22권1호
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• pp.1-8
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• 2017

About 20 chemical elements are nutritionally essential for humans with defined molecular functions. Several essential and nonessential biometals are either functional nutrients with antidiabetic actions or can be diabetogenic. A key question remains whether changes in the metabolism of biometals and biominerals are a consequence of diabetes or are involved in its etiology. Exploration of the roles of zinc (Zn) in this regard is most revealing because 80 years of scientific discoveries link zinc and diabetes. In pancreatic ${\beta}$- and ${\alpha}$-cells, zinc has specific functions in the biochemistry of insulin and glucagon. When zinc ions are secreted during vesicular exocytosis, they have autocrine, paracrine, and endocrine roles. The membrane protein ZnT8 transports zinc ions into the insulin and glucagon granules. ZnT8 has a risk allele that predisposes the majority of humans to developing diabetes. In target tissues, increased availability of zinc enhances the insulin response by inhibiting protein tyrosine phosphatase 1B, which controls the phosphorylation state of the insulin receptor and hence downstream signalling. Inherited diseases of zinc metabolism, environmental exposures that interfere with the control of cellular zinc homeostasis, and nutritional or conditioned zinc deficiency influence the pathobiochemistry of diabetes. Accepting the view that zinc is one of the many factors in multiple gene-environment interactions that cause the functional demise of ${\beta}$-cells generates an immense potential for treating and perhaps preventing diabetes. Personalized nutrition, bioactive food, and pharmaceuticals targeting the control of cellular zinc in precision medicine are among the possible interventions.

• STI Policy Review
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• 제1권3호
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• pp.1-15
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• 2010

This paper makes the case that a new policy strategy to enhance a global green recovery is needed urgently. The new strategy requires two essential elements. First, G20 economies should follow the lead of South Korea and China and turn their green stimulus investments into a serious long-term commitment, and to support these investments, they should adopt environmental pricing policies and instigate pricing and regulatory reforms to reduce carbon dependency. Second, the G20 also needs to target and coordinate assistance to developing economies in science, technology and innovation (STI) for clean energy. Such assistance is essential to help developing economies to overcome the skills, technological and capital gap that they face in clean energy technologies over the long term. Reform of the Clean Development Mechanism (CDM) is also necessary to establish a long-term global price signal for carbon, and to increase the coverage of developing economies, the sectors and technologies and the overall financing of clean energy projects. Formulating such a policy strategy should appeal to both the Asian-Pacific and Western economies comprising the G20, and by working together to formulate such a strategy, the G20 could lead the way toward a new era of global economic management and STI cooperation in clean energy.

• Journal of Astronomy and Space Sciences
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• 제35권3호
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• pp.175-183
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• 2018

Many recent satellites have mission periods longer than 10 years; thus, satellite-based local space weather monitoring is becoming more important than ever. This article describes the instruments and data applications of the Korea Space wEather Monitor (KSEM), which is a space weather payload of the GeoKompsat-2A (GK-2A) geostationary satellite. The KSEM payload consists of energetic particle detectors, magnetometers, and a satellite charging monitor. KSEM will provide accurate measurements of the energetic particle flux and three-axis magnetic field, which are the most essential elements of space weather events, and use sensors and external data such as GOES and DSCOVR to provide five essential space weather products. The longitude of GK-2A is $128.2^{\circ}E$, while those of the GOES satellite series are $75^{\circ}W$ and $135^{\circ}W$. Multi-satellite measurements of a wide distribution of geostationary equatorial orbits by KSEM/GK-2A and other satellites will enable the development, improvement, and verification of new space weather forecasting models. KSEM employs a service-oriented magnetometer designed by ESA to reduce magnetic noise from the satellite in real time with a very short boom (1 m), which demonstrates that a satellite-based magnetometer can be made simpler and more convenient without losing any performance.

• 한국식품영양학회지
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• 제31권1호
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• pp.89-93
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• 2018

In this study, we investigated the nutritional composition including proximate, amino acid, vitamin, minerals, and the antioxidant activity of green tea (Camellia sinensis) pollen grains collected by Apis mellifera bees, for use as a health food. The crude protein and fat content was estimated at 26.14% and 3.49%, respectively. Eighteen amino acids were identified in green tea pollen, including 8 essential amino acids and 10 non-essential amino acids. The predominant amino acids were glutamic acid, proline and aspartic acid accounting for about 33.3% of total free amino acids. The concentration of vitamin C was the highest value of 35.7%, followed by $B_3$ and $B_2$ among the detected vitamins. The predominant minerals were potassium (790.32 mg/100g), followed by phosphorus (707.52 mg/100g) and sulfur (302.67 mg/100g), whereas copper, zinc and sodium were detected as minor elements. The antioxidant activity and phenolic content accounted for 33.8% at $500{\mu}g/mL$ extract and $2.55 {\mu}g/mg$, respectively.

• 한국문헌정보학회지
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• 제39권2호
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• pp.57-84
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• 2005

교구$\cdot$ 설비기준은 학교 교육과정을 위한 기본 요소를 의미한다. 지식기반사회에서 학교도서관은 교육과정을 지원하고 정보활용과 독서지도를 위한 기본적인 교육환경이다. 따라서 학교도서관 교구 설비기준은 학교도서관의 사명을 담아야 하며, 교육적 역할에 적합한 구성요소를 포함하여야 한다. 그러나 현행 기준은 양적 질적 측면에서 불충분하다. 따라서 학교교구·설비기준 개정 시, 학교도서관 교구 ·설비기준은 특히 다음과 같은 내용을 포함하여야 한다. 1. 시설 지침; 2. 기본 설비 방안; 3. 교육적 역할에 적합한 교구 기준; 4. 기본 공간별 설비 종목; 5. 보다 상세한 정보기기 종목; 6. 특수학교도서관 기준 개선

• 대한정형도수물리치료학회지
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• 제7권2호
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• pp.23-39
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• 2001

Dysfunction of the anterior and dorsal muscles of the trunk have been studied in relation to low back pain of many years. Many muscles of the trunk are capable of contributing to the stabilization and protection of the lumbar spine, recent evidence has suggested that transversus abdominis may be critically involved and has been the focus of rehabilitation. The delay in onset of contraction of trunk muscles associated with movement of the upper or lower limb in patients with low back pain indicates a significant deficit in the automatic motor command for control of disturbance to the spine. The function of transversus abdominis has been largely ignored in the evaluation of spinal stabilization and protection. The most essential stabilizing muscles for the lumbar column are the transversus abdominis and the multifidus. Sling exercise therapy(SET) concept consists of a system of diagnosis and treatment. The system of diagnosis involves testing the muscle's tolerance through progressive loading in open and close kinetic chains. The SET system contains elements such as relaxation, increasing the range of movement, traction, training the stabilizing musculature, sensorimotor exercises, training in open and close kinetic chains, dynamic training of the mobilizing musculature, cardiovasc+ular exercises, group exercise, personal exercise at home. Sensorimotor training is an essential element of the SET concept. The emphasis is on closed kinetic chain exercises on an unstable surface, thereby achieving optimum stimulation of the sensorimotor apparatus.

• 대한예방한의학회지
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• 제5권1호
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• pp.31-40
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• 2001

Legal permissible limit of herbal drugs metal level in Korea is define 'less 30.0ppm in total(except mineral drugs)' including Pb Hg Cd As Cr Ni etc. This limit has a lot of problems in several factors, that is, not divide hazard and essential elements, not consider high and low toxic effect in each metal, not calculate dose-response relationship and average health behavior in Korean etc. As a that result, It has strong limits and weakness in the basic toxicology and Oriental medicine. To improve and correct these factors, We need to several new approach as like below. It must be radical study following problems in short and middle-long period in the future, toxic metal and essential element must be divide to basic toxicology and also be diverse toxic effect. But mineral drugs that included a amount of severe toxic metals is being used as active prescription drug until now. If toxic, safety and side-effect of metals will be considered, mineral drugs must prohibit instantly or use at least after examined toxic effect. But one of the most important things about herbal drugs contamination, all people and department (government, farmer and trader, oriental medicine doctors and association) will be participate cooperative and collection for preventive or the least contamination in herbal drugs.

• The Journal of Asian Finance, Economics and Business
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• 제8권12호
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• pp.85-94
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• 2021

Infrastructure capacities are essential elements and one of the sustainable lines to drive economic growth. Infrastructure development, both physical and social, is vital to sector-wise economic development. However, there is limited evidence of how infrastructure development in certain sectors benefits the economy as a whole. This study explains the relationships between infrastructure and economic growth in selected middle-income Asian countries, highlighting the essential criteria to benefit from both physical and social infrastructure, as well as sectoral (agriculture, industry, and services) economic output. The research uses the data from 1990 to 2020 for empirical estimations. The study used Levin, Lin, & Chu test, ADF- Fischer chi- Square, and PP- Fischer Chi-Square to test unit root and to observe the stationary nature of the panel. Padroni and Kao cointegration is applied to check the cointegration among different panes. A Fully Modified OLS was employed for checking the association between physical and social infrastructure and economic growth. Results show that physical and social infrastructure negatively impact sectoral output in Asia's middle-income countries. Apart from infrastructure the per capita GDP growth, tax to GDP ratio, and population growth shows a simultaneous relation between infrastructure and sectoral economic growth.

• Computers and Concrete
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• 제33권5호
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• pp.545-557
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• 2024

A real-case incident occurred where a 9-meter-high segment of a pre-fabricated concrete separation wall unexpectedly collapsed. This collapse was triggered by improperly depositing excavated soil against the wall's back, a condition for which the wall segments were not designed to withstand lateral earth pressure, leading to a flexural failure. The event's analysis, integrating technical data and observational insights, revealed that internal forces at the time of failure significantly exceeded the wall's capacity per standard design. The Lattice Discrete Particle Model (LDPM) further replicates the collapse mechanism. Our approach involved defining various parameter sets to replicate the concrete's mechanical response, consistent with the tested compressive strength. Subsequent stages included calibrating these parameters across different scales and conducting full-scale simulations. These simulations carried out with various parameter sets, were thoroughly analyzed to identify the most representative failure mechanism. We developed an equation from this analysis that quickly correlates the parameters to the wall's load-carry capacity, aligned with the simulation. Additionally, our study examined the wall's post-peak behavior, extending up to the point of collapse. This aspect of the analysis was essential for preventing failure, providing crucial time for intervention, and potentially averting a disaster. However, the reinforced concrete residual state is far from being fully understood. While it's impractical for engineers to depend on the residual state of structural elements during the design phase, comprehending this state is essential for effective response and mitigation strategies after initial failure occurs.

• 한국실내디자인학회논문집
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• 제25권1호
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• pp.132-141
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• 2016

For those with disabilities, the residential area is the primary place to adapt the disabilities. Since the quality of the area gives a critical impact on their quality of life, it is essential to finding the measures to create the residential environment that supports their independence. In this regard, this study aimed to compare and analyze the interior elements of the houses that hinder the independence of the physically handicapped in the rural and urban areas, and conducted a survey on a total of 80 physically challenged in Seoul and Yeongwol (40 for each area). As a result, the respondents answered that the houses where they are currently living are hindering their independence regardless of area, and there were regional differences in the level of inconvenience with the size of living room, size of utility room, location of room, lighting and heating environment, ventilation system, deteriorated wallpapers and finishing materials, threshold and floor level difference and humidity control. This study has significance by providing the realistic measures to improve the housing environment of the physically challenged living in the rural and urban areas to be customized to them to increase their quality of life.