• Title/Summary/Keyword: EUGENE

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Clinical and Radiological Outcomes of Foraminal Decompression Using Unilateral Biportal Endoscopic Spine Surgery for Lumbar Foraminal Stenosis

  • Kim, Ju-Eun;Choi, Dae-Jung;Park, Eugene J.
    • Clinics in Orthopedic Surgery
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    • v.10 no.4
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    • pp.439-447
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    • 2018
  • Background: Since open Wiltse approach allows limited visualization for foraminal stenosis leading to an incomplete decompression, we report the short-term clinical and radiological results of unilateral biportal endoscopic foraminal decompression using $0^{\circ}$ or $30^{\circ}$ endoscopy with better visualization. Methods: We examined 31 patients that underwent surgery for neurological symptoms due to lumbar foraminal stenosis which was refractory to 6 weeks of conservative treatment. All 31 patients underwent unilateral biportal endoscopic far-lateral decompression (UBEFLD). One portal was used for viewing purpose, and the other was for surgical instruments. Unilateral foraminotomy was performed under guidance of $0^{\circ}$ or $30^{\circ}$ endoscopy. Clinical outcomes were analyzed using the modified Macnab criteria, Oswestry disability index, and visual analogue scale. Plain radiographs obtained preoperatively and 1 year postoperatively were compared to analyze the intervertebral angle (IVA), dynamic IVA, percentage of slip, dynamic percentage of slip (gap between the percentage of slip on flexion and extension views), slip angle, disc height index (DHI), and foraminal height index (FHI). Results: The IVA significantly increased from $6.24^{\circ}{\pm}4.27^{\circ}$ to $6.96^{\circ}{\pm}3.58^{\circ}$ at 1 year postoperatively (p = 0.306). The dynamic IVA slightly decreased from $6.27^{\circ}{\pm}3.12^{\circ}$ to $6.04^{\circ}{\pm}2.41^{\circ}$, but the difference was not statistically significant (p = 0.375). The percentage of slip was $3.41%{\pm}5.24%$ preoperatively and $6.01%{\pm}1.43%$ at 1-year follow-up (p = 0.227), showing no significant difference. The preoperative dynamic percentage of slip was $2.90%{\pm}3.37%$; at 1 year postoperatively, it was $3.13%{\pm}4.11%$ (p = 0.720), showing no significant difference. The DHI changed from $34.78%{\pm}9.54%$ preoperatively to $35.05%{\pm}8.83%$ postoperatively, which was not statistically significant (p = 0.837). In addition, the FHI slightly decreased from $55.15%{\pm}9.45%$ preoperatively to $54.56%{\pm}9.86%$ postoperatively, but the results were not statistically significant (p = 0.705). Conclusions: UBEFLD using endoscopy showed a satisfactory clinical outcome after 1-year follow-up and did not induce postoperative segmental spinal instability. It could be a feasible alternative to conventional open decompression or fusion surgery for lumbar foraminal stenosis.

Study for implementation of smart water management system on Cisangkuy river basin in Indonesia (인도네시아 찌상쿠이강 유역의 지능형 물관리 시스템 적용 연구)

  • Kim, Eugene;Ko, Ick Hwan;Park, Chan Ho
    • Proceedings of the Korea Water Resources Association Conference
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    • 2017.05a
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    • pp.469-469
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    • 2017
  • 기후 변화 및 환경오염으로 인하여 물부족 국가가 세계적으로 증가하고 있는 추세이며, 특히 집중형 강우의 형태가 많아짐에 따라 홍수피해 및 상수공급의 문제가 사회적으로 큰 이슈가 되고 있다. 최근 20여 년간의 급속한 경제성장과 도시화 과정에서 인도네시아는 인구와 산업의 과도한 도시집중으로 지난 1960-80년대 한국이 산업화 과정에서 겪었던 것보다 훨씬 심각한 환경문제에 직면하고 있으며, 자카르타와 반둥을 포함하는 광역 수도권 지역의 물 부족과 수질 오염, 환경문제가 이미 매우 위험한 수준에 도달하고 있는 실정이다. 특히, 찌따룸강 중상류에 위치한 인도네시아 3대 도시인 반둥시는 고질적인 용수부족 문제를 겪고 있다. 2010년 현재 약 일평균 15 CMS의 용수가 부족한 상황이며, 2030년에는 지속적인 인구증가로 약 23 CMS의 용수가 추가로 더 필요한 것으로 전망된다. 이러한 용수공급 문제 해결을 위해 반둥시 및 찌따룸강 유역관리청은 댐 및 지하수 개발, 유역 간 물이동 등의 구조적인 대책뿐만 아니라 비구조적인 대책으로써 기존 및 신규 저수지 연계운영을 통한 용수이용의 효율성을 높이는 방안을 모색하고 있다. 이에 따라 본 연구에서는 해당유역의 용수공급 부족 문제를 해소할 수 있는 비구조적인 대책의 일환으로써 다양한 댐 및 보, 소수력 발전, 취수장 등 유역 내 수리 시설물의 운영 최적화를 위한 지능형 물관리 시스템 적용 방안을 제시하고자 한다. 본 연구의 지능형 물관리 시스템은 센서 및 사물 인터넷(Internet of Things, IoT), 네트워크 기술을 바탕으로 시설물 및 운영자, 유관기관 간의 양방향 통신을 통해 유기적인 상호연계 체계를 제공 할 수 있다. 또한 유역의 수문상황과 시설물의 운영현황, 용수공급 및 수요 현황을 실시간으로 확인함으로써 수요에 따른 즉각적인 용수공급량의 조절이 가능하다. 또한, 빅데이터 분석 및 기계학습(Machine Learning)을 통해 개별 물관리 시설물에 대한 최적 운영룰을 업데이트할 수 있으며, 유역의 수문상황과 용수 수요 현황을 고려하여 최적의 용수공급 우선순위를 선정할 수 있다. 지능형 물관리 시스템 개발의 목적은 찌상쿠이 유역의 수문현황을 실시간으로 모니터링하고, 하천시설물의 운영을 분석하여 최적의 용수공급 및 배분을 통해 유역의 수자원 활용 효율성을 향상시키는 데 있다. 이를 위해 수문자료의 수집체계를 구축하고 기관간 정보공유체계를 수립함으로써 분석을 위한 기반 인프라를 구성하며, 이를 기반으로 유역 유출을 비롯한 저수지 운영, 물수지 분석을 수행하고, 분석 및 예측결과, 과거 운영 자료를 토대로 새로운 물관리 시설 운영룰 및 시설물 간 연계운영 방안, 용수공급 우선순위 의사결정 등을 지원하고자 한다. 본 연구의 지능형 물관리 시스템은 통합 DB를 기반으로 수리수문 현상의 모의 분석을 통해 하천 시설물 운영의 합리적 기준을 제시함으로써 다양한 관리주체들의 시설물운영에 대한 이견 및 분쟁을 해소하고, 한정된 수자원과 다양한 수요 간의 효율적이고 합리적인 분배 및 시설물 운영문제를 해결하기 위한 의사결정도구로써 활용할 수 있을 것으로 기대된다.

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MD Simulation Study for Preferred Structure of Glycerol Backbone in 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) Molecule According to Solvent Properties (용매 특성에 따른 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 분자에서 글리세롤 골격 구조에 대한 MD 시뮬레이션 연구)

  • Yang, Ji-yun;Huh, Eugene;Ahn, Ik-sung;Mhin, Byung-jin
    • Journal of the Korean Chemical Society
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    • v.65 no.3
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    • pp.179-184
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    • 2021
  • In this study, the molecular dynamics simulation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) single molecule was conducted by changing the solvent properties in order to investigate the change in the glycerol backbone structure in phospholipids according to the solvent properties. DOPC has three different conformations according to glycerol C1-C2 bond: A(θ3 = trans, θ4 = gauche), B(θ3 = gauche, θ4 = gauche-), C(θ3 = gauche-, θ4 = trans). Changes in the glycerol backbone structure of the DOPC were examined using the solvent's dielectric constant and surface tension constant as variables. As a result, the population of the B structure increased as the dielectric constant increased. The reason is that the solvation energy of the B structure is larger than that of A. In addition, as the surface tension constant increased, the population of the B structure increased because the surface area of B was smaller than that of A. The results of these studies are expected to be used in the study of phospholipid structure in the future.

Analysis of Teacher Understanding After Adapting Collaborative Problem-Solving for Character Competence (CoProC) Program on Science Education (과학교육 기반 인성역량 함양을 위한 협력적 문제해결(CoProC) 프로그램 실천 교사들의 이해 분석)

  • Kang, Eugene;Park, Jihun;Park, Jongseok;Nam, Jeonghee
    • Journal of the Korean Chemical Society
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    • v.65 no.2
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    • pp.133-144
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    • 2021
  • Science teachers in elementary schools and secondary schools recognize the necessity of character education, feeling difficulties such as evaluation methods, mood of competition, extra work and lack of time according to previous research, which were based on answers from science teachers not experiencing character education. As a rare study of teacher experiencing, previous researches didn't fully address the problems and suggestions about adopting character education in science classrooms. This study is about teacher practice of character education on site with the CoProC (Collaborative Problem-Solving for Character Competence) program in science classes with which other previous studies shed new light. Five teachers, adapting the CoProC program in their science classes, participated in two interviews, sharing their student achievement in character education. Results showed that student achievement was high when their teacher had experienced the training program, development, and classes of CoProC rather than their normal teaching career. Teacher recognition on the aims of CoProC influenced difficulties, evaluation, and feedback.

Experimental Study on the Applicability of Reactivity SiO2 Nano-Materials as Cement Composites (실리케이트계 반응성 나노소재의 시멘트 혼화재로써 적용 가능성에 대한 실험적 연구)

  • Kim, Won-Woo;Moon, Jae-Heum;Baek, Chul-Woo;Yang, Keun-Hyeok
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.9 no.4
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    • pp.529-536
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    • 2021
  • In this study, nano-silica and nano-titanium were selected to determine the possibility of applying the binder to reactive nano materials. The basic characteristics of the nano material candidate group were reviewed. and the reactivity of nano materials was reviewed through K-value. The reactivity of the nano silicate materials was measured to be high. Therefore, as a final candidate group, nano silicate materials were selected. The finally selected reactive nano material was reviewed for its usability as a construction binder. The mechanical properties and unit weight of cement paste were reviewed using silica fume and blast furnace slag and nano materials. When cement composites with nano silicate materials, it was confirmed that it was effective in improving the mechanical performance and decrease the unit weight of cement composites.

The Pigments Variation of Phytoplankton in the Seomjin and Yeongsan River estuary (섬진강과 영산강 하구의 식물플랑크톤 기원 색소분포 변동)

  • Jeon, Hyeji;Lee, Eugene;Son, Moonho
    • Journal of Marine Life Science
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    • v.5 no.2
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    • pp.99-106
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    • 2020
  • To investigate effect of variation in physiochemical conditions due to river discharge on phytoplankton, field surveys were conducted in the Seomjin and Yeongsan River estuaries from April to November 2016. The concentrations of DIN and DSi in Seomjin River estuary were gradually low as distance from upstream. On the other hands, the concentrations of DIN and DSi in Yeongsan River estuary were critically high at upstream, due to which is characterized as semi-enclosed eutrophic area. A total of 12 phytoplankton pigments were analyzed, and the distribution of each taxa was investigated using indicator for each phytoplankton taxa. Fucoxanthin, an indicator pigment of diatoms, showed an average of 0.61±1.00 ㎍ l-1 and 0.76±1.22 ㎍ l-1 in the Seomjin and Yeongsan River estuaries, respectively. Concentration of fucoxanthin was more than twice that of other pigments except chlorophyll a., indicating that diatoms were dominant taxa. Peridinin, an indicator pigment of dinoflagellate, showed some similar tendency to the microscopic observation, but mismatch results were also present, indicating a technical limitation of pigment analysis. Chlorophyll b, alloxanthin, and zeaxanthin, which are indicator pigments of green algae, cryptomonads, and cyanobacteria, were detected in both estuaries even though those taxa were not detected in microscopic observation. This indicates that the two estuaries were affected by freshwater species. Here, we can suggest that phytoplankton composition in estuary was directly influenced by the inflow from upstream. In particular, the phytoplankton population dynamics in Yeongsan River estuary was greatly associated with a large-scale artificial dyke, especially in summer rainy season. On the other hands, the seasonal and horizontal distribution of phytoplankton in Seomjin River estuary has changed along the salinity gradients and inflow-related changes.

Surgical outcomes of sternal rigid plate fixation from 2005 to 2016 using the American College of Surgeons-National Surgical Quality Improvement Program database

  • Tran, Bao Ngoc N.;Chen, Austin D.;Granoff, Melisa D.;Johnson, Anna Rose;Kamali, Parisa;Singhal, Dhruv;Lee, Bernard T.;Fukudome, Eugene Y.
    • Archives of Plastic Surgery
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    • v.46 no.4
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    • pp.336-343
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    • 2019
  • Background Sternal rigid plate fixation (RPF) has been adopted in recent years in high-risk cases to reduce complications associated with steel wire cerclage, the traditional approach to sternal closure. While sternal RPF has been associated with lower complication rates than wire cerclage, it has its own complication profile that requires evaluation, necessitating a critical examination from a national perspective. This study will report the outcomes and associated risk factors of sternal RPF using a national database. Methods Patients undergoing sternal RPF from 2005 to 2016 in the American College of Surgeons-National Surgical Quality Improvement Program were identified. Demographics, perioperative information, and complication rates were reviewed. Logistic regression analysis was performed to identify risk factors for postoperative complications. Results There were 381 patient cases of RPF identified. The most common complications included bleeding (28.9%), mechanical ventilation >48 hours (16.5%), and reoperation/readmission (15.2%). Top risk factors for complications included dyspnea (odds ratio [OR], 2.672; P<0.001), nonelective procedure (OR, 2.164; P=0.010), congestive heart failure (OR, 2.152; P=0.048), open wound (OR, 1.977; P=0.024), and operating time (OR, 1.005; P<0.001). Conclusions Sternal RPF is associated with increased rates of three primary complications: blood loss requiring transfusion, ventilation >48 hours, and reoperation/readmission, each of which affected over 15% of the study population. Smokers remain at an increased risk for surgical site infection and sternal dehiscence despite RPF's purported benefit to minimize these outcomes. Complications of primary versus delayed sternal RPF are roughly equivalent, but individual patients may perform better with one versus the other based on identified risk factors.

Gestational Exposure to Pesticides Induces Oxidative Stress and Lipid Peroxidation in Offspring that Persist at Adult Age in an Animal Model

  • Ndonwi, Elvis Ngwa;Atogho-Tiedeu, Barbara;Lontchi-Yimagou, Eric;Shinkafi, Tijjani S.;Nanfa, Dieudonne;Balti, Eric V.;Indusmita, Routray;Mahmood, Amena;Katte, Jean-Claude;Mbanya, Armand;Matsha, Tandi;Mbanya, Jean Claude;Shakir, Ali;Sobngwi, Eugene
    • Toxicological Research
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    • v.35 no.3
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    • pp.241-248
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    • 2019
  • Pesticide exposure may induce biochemical alterations including oxidative stress and lipid peroxidation. However, in the context of developmental origin of health and disease, putative trans-generational effect of exposure to pesticides are insufficiently studied. We therefore aimed to evaluate the biochemical effect of gestational exposure to four pesticides on female Wistar rats and their offspring at adult age. We studied 30 female nulliparous Wistar rats divided into 5 equal groups. Group 1 served as the control group and received distilled water while group 2, 3, 4 and 5 received orally pesticide 1 (imidacloprid), pesticide 2 (chlorpyrifos), pesticide 3 (imidacloprid + lambda cyhalothrin) and pesticide 4 (oxamyl) respectively once daily throughout gestation at a dose equivalent to 1/10 lethal dose 50. The mothers were followed up until one month post gestation. The offspring were followed up from birth until adult age (12 weeks). In all animals at each time point we evaluated malondialdehyde (MDA), oxidative stress and liver function enzymes. There was similar variation of total body weight in all the groups during and after gestation. However, Female Wistar rats of the exposed groups had significant alterations in liver SOD (-30.8% to +64.1%), catalase (-38.8% to -85.7%) and GSH (-29.2% to -86.5%) and; kidney catalase (> 100%), GSH (> 100%). Moreover, MDA, alanine transaminase (ALT) and aspartate transaminase (AST) levels were significantly higher in pesticide exposed rats compared to the control group. Similar alterations in antioxidant enzymes, MDA and liver function enzymes were observed in offspring of treated rats evidenced at weaning and persisting until adult age. Exposure to pesticides causes oxidative stress and lipid peroxidation in exposed female Wistar rats and their offspring. The persistence in offspring at adult age suggests transgenerational adverse effects.

A study on World Heritage conservation policies through the case of the Dresden Elbe Valley (드레스덴 엘베계곡의 사례로 본 세계유산 보존 정책)

  • Jo, Eugene
    • Korean Journal of Heritage: History & Science
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    • v.48 no.2
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    • pp.96-109
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    • 2015
  • The Dresden Elbe Valley of Germany was delisted from the World Heritage List after a long dispute amongst the city of Dresden, UNESCO and the World Heritage Committee upon a plan to build a four-lane bridge within the boundaries of the property. The plan was claimed to threaten the Outstanding Universal Value of the heritage embedded in the view of the river landscape. However looking back on the necessity of the bridge in order to maintain the city dynamics and the needs of the local population, it is possible to diagnose that plans for the bridge had a rather different nature from the usual urban 'development' plans appearing in the vicinity of other World Heritage properties. This article examines the process that led to the delisting of the Elbe Valley from the World Heritage List and assesses the problems arising between the entities which determine the value of the heritage and the entities that implement conservation measures. Recognizing the necessity of involving the local residents, this article stresses the importance of the role of communities in heritage conservation. It is also important to set up dependable directions for establishing conservation policies which takes into account the changing dynamics of the living environment, and sound methods for assessing the impact of future projects on the heritage.

The Components of the Child-care Teachers' Professional Vision Through the Video-based Learning Community: Focusing on Selective Attention and Knowledge-based Reasoning (비디오 활용 학습공동체를 통해 나타난 보육교사의 전문적 시각의 구성 요소: 선택적 주의와 인지 기반 추론을 중심으로)

  • Kim, Soo Jung;Lee, Young Shin;Lee, Min Joo
    • Korean Journal of Child Education & Care
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    • v.19 no.1
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    • pp.27-43
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    • 2019
  • Objective: The purpose of this study is to investigate how the child care teachers experience about professional vision development through participating in video clubs with their peers while watching videos about their interactions with children in the classroom. Methods: We selected three child care teachers in a day care center in Seoul area and conducted the qualitative case study. Video clubs were designed to support the quality of teacher-child interaction by developing child-care teachers' professional vision. And the video clubs used the self-reflection process and cooperative self-reflection process as an important educational method. Results: Teachers were able to experience the change of attention in watching their interaction scene through the 4-time video club participation and to have opportunity for educational (knowledge based) reasoning. Particularly, through participation in the video club, the teacher could pay attention to teachers' intention, teachers' decision making process, and child's intention. In addition, through video club participation, the teachers experienced educational interpretation based on children's thinking and interest; and reasoning through reflective thinking about the results of teaching behavior. This change of professional vision was possible through mutual scaffolding through cooperative reflection among participating teachers. Conclusion/Implications: Based on the results of this study we discussed the importance of the professional vision development of the child care teachers and the effectiveness of the video club for supporting their professional vision development.