• The Journal of Korean Physical Therapy
• /
• 제26권5호
• /
• pp.344-350
• /
• 2014

Purpose: The purpose of this study was to translate and culturally adapt the International Classification of Functioning, Disability and Health (ICF) into the Korean language. Methods: The process of translation and adaptation of the ICF used here followed the translation guidelines of WHO. Implementation of this procedure comprised of four steps; forward translation, expert panel back-translation, pre-testing and cognitive interviewing, and final adaptation. The translators included health professionals with knowledge of ICF and non-health professionals blinded to the ICF. Clinical academics with significant experience in the use of disability survey, medical doctors, special educators, related policy makers, clinicians, architecture professionals, and international experts in ICF were invited to integrate all versions of the ICF for testing; 151 clinicians volunteered from 19 medical institutes across the country. Four different core-sets and a questionnaire were used for testing its practical usability and adaptation. Results: All translations were reviewed and a consensus was reached on any discrepancy from the earlier versions. Over 90% of the newly translated version of K-ICF was found to be different from the 2004 K-ICF version in the ICF language. Understanding of K-ICF language was responded difficult and very difficult by 50% of participants, whereas its practical use was responded 'useful' by more than 50% of subjects. Conclusion: It can be suggested that the new version of K-ICF should be widely used for final adaptation in the field of areas. Future studies will be required for implementation of K-ICF.

• Journal of Interdisciplinary Genomics
• /
• 제1권1호
• /
• pp.10-13
• /
• 2019

A 10-year and 5 month-old girl with developmental delay, intellectual disability, attention deficit hyperactivity disorder, poor weight gain, and microcephaly was transferred to our pediatric clinic for genetic evaluation. Her height was within the 5-10th percentile, and her weight was under the 3rd percentile. On the social maturity scale, her developmental status was scored as 3 years 9 months for social age, and the social quotient was 35.98. A chromosomal microarray analysis was performed and the microduplication at chromosome 16p was observed: arr[GRCh37] 16p11.2 (29580020_30190029)${\times}3$. Currently, the patient is diagnosed with Grade 2 intellectual disability and is attending a computerized cognitive rehabilitation class twice weekly. In addition, nutritional support and growth follow up are also ensured in the Pediatric Gastrointestinal and Endocrinology clinic.

• Journal of Genetic Medicine
• /
• 제17권2호
• /
• pp.79-82
• /
• 2020

In epilepsy-aphasia spectrum (EAS) disorders, mutations in the glutamate receptor ionotropic N-methyl-D-aspartate type subunit 2A (GRIN2A) have become important for screening the disease. Research into the phenotypic variability of several types of neurologic impairment involving these mutations is in progress. However, the non-neurological problems related to these mutations are poorly understood. EAS disorders usually have epileptic, cognitive, or behavioral manifestations. In this case report, we present a female patient with epilepsy, delay in expressive language and social development, and intellectual disability with low intelligence quotient and memory quotient, but normal motor development. Through genetic analysis, she was found to have a missense and a nonsense mutation in GRIN2A (c.1770A>C; p.Lys509Asn and c.3187G>T; p.Glu1063∗, respectively) and we consider the nonsense mutation as 'pathogenic variant'. She was also discovered to have congenital hypothyroidism, growth hormone deficiency and Rathke's cleft cyst in the brain, which were previously unknown features of GRIN2A mutation. Our findings should widen understanding of the spectrum of GRIN2A phenotypes, and emphasize the need for more research into the association between GRIN2A mutations and non-neurologic clinical presentations.

• 재활복지
• /
• 제14권3호
• /
• pp.225-256
• /
• 2010

본 연구는 초등학교 지적장애아동의 자세조절 특성을 파악하기 위해 시각, 안뜰감각 그리고 몸감각을 조합하여, 실험 조건에 따라 자세유지를 위하여 어떤 감각을 활용하고 있는지, 부적절한 감각자극에 대해서 통합시스템에서 어떻게 반응하는지, 외부 동요에 대해 신경근육의 자세조절 전략 시 동원되는 근육의 수축 개시시간과 개시순서를 각각 측정하여, 지적장애 아동의 자세조절 특성을 살펴보고, 나아가 초등학교 지적장애아동과 일반아동 간에 어떠한 차이가 있는지를 비교분석하여 자세조절능력 향상 프로그램에 적용 시 방향을 제시해주는데 있다. 이를 위하여 성별과 연령을 고려하여 초등학교 지적장애아동 26명과 일반아동 26명의 아동으로부터 자세조절능력을 비교하였다. 그 결과 자세조절과 감각계와의 관계를 파악한 평형점수와 감각활용 분석, 엉덩관절 전략에 의지하는 자세조절 전략, 근수축 개시지연과 근수축 개시순서의 변화 등을 종합해 볼 때 초등학교 지적장애아동의 자세조절의 문제는 운동시스템, 감각시스템, 통합시스템의 자세조절 시스템 전반에 걸친 총체적인 문제로 나타났다. 따라서 초등학교 지적장애아동의 자세조절 문제 해결을 위해서는 운동시스템, 감각시스템, 통합시스템을 포함하는 포괄적 자세조절 훈련 프로그램의 접근이 필요하다는 것을 알 수 있다. 자세조절 프로그램을 구성할 때, 다양한 감각을 제공하여 주고, 제공된 감각을 효율적으로 활용할 수 있는 감각훈련과 함께 고위중추에서 입력된 감각들을 정상적인 자세조절 발달에 활용할 수 있도록 훈련 시켜주어야 한다. 적응 반응을 계획하고 조직화하여 의미 있는 활동을 통해 중추신경계의 처리능력을 향상시키는 치료프로그램이 제공되어야 한다. 또한 자세조절을 안정적으로 할 수 있는 안정성 한계를 넓힐 수 있는 신경발달학적 치료와 함께, 근골격계에서 빠른 근수축 반응과 효율적인 근수축 개시순서를 유발 할 수 있도록 고유수용성 운동조절 프로그램, 자세반응 촉진 프로그램과 같은 훈련이 필요하다고 할 수 있다.

• 한국콘텐츠학회논문지
• /
• 제21권1호
• /
• pp.572-578
• /
• 2021

본 연구는 지체장애인을 대상으로 인공지능 스피커에 대한 인지적 요소와 감정적 요소가 인공지능 스피커 사용 의도에 미치는 영향을 검증하는 것을 목적으로 하였다. 연구방법은 지체장애인을 대상으로 온라인 설문 조사를 실시하였다. 인공지능 스피커에 대한 인지도와 필요도, 인지된 친밀함과 즐거움, 사용 의도를 파악하였으며, 각 변인이 지체장애인의 인공지능 스피커 사용 의도에 미치는 영향력을 확인하기 위해 다중회귀분석(Multiple linear regression analysis)을 실시하였다. 연구 결과, 지체장애인의 인공지능 스피커에 대한 인지된 즐거움은 사용 의도에 유의한 정적 영향을 나타내었다. 그러나 지체장애인의 인공지능 스피커에 대한 인지도와 필요도, 인지된 친밀함은 인공지능 스피커 사용 의도에 통계적으로 유의미한 영향을 나타내지 않는 것으로 분석되었다. 본 연구의 결과는 장애인의 인공지능 스피커 사용 의도 향상을 위해 즐거움 요소를 강화하는 것이 필요함을 시사하며, 장애인을 위한 인공지능 제품과 맞춤형 서비스를 개발하기 위한 기초자료를 제공하는 점에서 의의가 있다.

• 한국응용과학기술학회지
• /
• 제37권5호
• /
• pp.1454-1464
• /
• 2020

연구목적은 성인 지적장애인들의 수영 프로그램 참여에 따른 자아효능감과 운동 몰입, 건강관련 삶의 질의 변화를 분석하는 데 있다. 연구대상은 지적장애인 거주시설에서 거주하고 있는 성인 지적장애인 12명이며, 수영 프로그램에 12주간 참여하였다. 이에 따라 대상자들의 자아효능감과 운동 몰입, 건강관련 삶의 질의 변화를 분석하였다. 자아효능감 평가는 전반적 자아효능감 척도를 활용하였으며, 일반적, 사회적 신체적 자아효능감을 평가하였다. 운동 몰입 평가는 스포츠 몰입척도를 활용하였으며, 인지몰입과 행위몰입의 수준을 평가하였다. 건강관련 삶의 질 평가는 건강관련 삶의 질 척도를 활용하여 전반적 건강관련 삶의 질의 수준을 평가하였다. 그 결과, 대상자들은 수영 프로그램 참여에 따라 자아효능감과 운동 몰입, 건강관련 삶의 질의 수준이 통계적으로 유의미하게 향상되었다. 수영 프로그램의 참여는 성인 지적장애인들의 자아효능감과 운동 몰입, 건강관련 삶의 질의 수준을 향상시키는 데 긍정적으로 작용한다. 이에 따라서, 성인 지적장애인들을 대상으로 수영 프로그램의 적용을 고려해볼 필요가 있을 것이다.

• 한국의류학회지
• /
• 제45권5호
• /
• pp.788-803
• /
• 2021

This study aims to obtain basic data to develop clothes for dementia patients by classifying types of dementia patients. Data was collected from those dementia patients who entered a nursing home. This study analyzed a total of 221 sheets. Furthermore, descriptive statistics, cross-tabulation, and K-means clustering were performed for statistical processing using Minitab 14. As a result, dementia patients were classified into four types: inactive-dependent, active-problematic behavior, activity-autonomy, and inactive-offensive. Inactive-dependent type was a group with the most severe disability in cognitive and daily activity functions; however, they lacked behavioral and psychological symptoms and problematic behavior with clothes. Active-problematic behavior type showed the most behavioral and psychological problems and problematic behavior with clothes. Activity-autonomy type was a group without any problematic behaviors. Moreover, the inactive-offensive type had very good cognitive function toward humans. The study imply that it is necessary to provide clothes with proper functions based on the types of patients rather than providing them uniform clothes because clinical and clothes behaviors differ significantly depending on the types of dementia patients.

• 대한간호학회지
• /
• 제22권4호
• /
• pp.464-475
• /
• 1992

Head Injuries due to traffic accidents are now the leading cause of death and long term disability in males between 30-50 years. Many patients with head injuries experience mild dysfunction of cognition without major neurosurgical problems, and this may interfere with successful rehabilitation. However, not many studies have been done to investigate the cognitive functioning following mild head injuries. The purpose of this study was to obtain injured patient's dermographic data including medical, neuropsychological and social data, and to investigate the cause of injury and alcohol use at the time of injury. This study focused on the recovery of cognitive function in patients with head injuries and used the Mini Mental State Examination(MMSE) score and its correlation with dermographic and social data. Data on 77 patients with minor head injuries who were admitted to the department of Neurosurgery in 3 and I hospital in Dae Jun from September 1991 to February 1992 were analyzed. The findings of this study are as follows ; 1) Out of the 77 cases reviewed in this study, 62 were male, 15 were female. 2) A higher incidence of injury was observed between 7:00 PM and 12:00 PM. 3) The most common cause of head injury in traffic accidents was pedestrian accidents, and the next most frequent cause was motorcycle accidents. 4) Thirteen of the 77 cases in this study were under the influence of alcohol at the time of injury, and they were all male. 5) The MMSE scores one month after injury and at discharge were significantly lower in patients with head injuries that included skull fractures than in patients without skull fractures, suggesting lower cognitive function in patients with skull fractures. 6) The level of consciousness at admission and three days after admission measured by the GCS for drivers under the influence of alcohol was lower than for sober drivers. The MMSE score was also lower for drunken drivers. 7) The MMSE score one month after the injury had a reciprocal relationship with the age of the patient. 8) The MMSE score one month after the injury and at discharge were highly correlated with the duration of unconsciousness. 9) The MMSE score one month after injury and at discharge were highly correlated with the GCS scores at admission, three days after admission, and one week after admission.

• Journal of Ginseng Research
• /
• 제31권1호
• /
• pp.44-50
• /
• 2007

Ginseng powerfully tonifies the original Qi. Ginseng used for insomnia, palpitations with anxiety, restlessness from deficient Qi and blood and mental disorientation. In order to investigate whether Ginseng cerebral ischemia-induced neuronal and cognitive impairments, we examined the effect of Ginseng on ischemia-induced cell death in the hippocampus, and on the impaired learning and memory in the Morris water maze and passive avoidance in rats. Ginseng when administered to rat at a dose of 200 mg/kg i.p. water extracts to 0 minutes and 90 minutes after 4-VO, significantly neuroprotective effects by 86.4% in the hippocampus of treated rats. For behavior test, rats were administered Ginseng (200mg/kg p.o.) daily for two weeks, followed by their training to the tasks. Treatment with Ginseng produced a marked improvement in escape latency to find the platform in the Morris water maze. Ginseng reduced the ischemia-induced learning disability in the passive avoidance. Consistent with behavioral data, treatments with Ginseng reduced jschemia-induced cell death in the hippocampal CA1 area. Oxidative stress is a causal factor in the neuropathogenesis of ischemic-reperfusion injury. Oxidative stress was examined in a rat model of global brain ischemia. The effects of Ginseng on lipid peroxidation (inhibition of the production of malondialdehyde, MDA) in different regions of the rat brain were studied. Ferrous sulfate and ascorbic acid (FeAs) were used to induce lipid peroxidation. The antiperoxidative effect showed 48-72% protection from tissue damage as compared with untreated animals. These results showed that Ginseng have a protective effect against ischemia-induced neuronal loss and learning and memory damage.

• 대한한방내과학회지
• /
• 제19권1호
• /
• pp.97-113
• /
• 1998

BACKGROUND The purpose of this study was to investigate disability of the patients after stroke, clinical applicability and usefulness of the FIM in evaluating the functional abilities and to assess the characteristics of the patients after stroke. And this study examined difference by predictive factors on the treatment outcome. METHOD The study was composed of 31 stroke patients who were within 1 week after stroke and had been treated in hospital more than 4 weeks. Improving rate was measured by using the Functional Independence Measure(FIM), and the correlation was analyzed between Motor FIM and Cognitive FIM. We analyzed significant meaning statistically in the mean value of FIM. RESULT 1. There was no significant meaning statistically in the mean value of FIM that was between both at admission and after 2 weeks. But there was proportional correlation between both at admission and after 4 weeks, and significant meaning statistically. 2. There was proportional correlation between both FIM and Motor FIM, and significant meaning statistically. But there was no significant meaning statistically between both FIM and Cognitive FIM. 3. There was no significant meaning statistically between both FIM and sex, age, side of weakness, stroke subtype, hypertension, hypercholesterolemia, diabetes mellitus, heart disease, starting point of rehabilitation therapy and past history of cerebral vascular accident. While dysarthria affected functional recovery in stroke patients, and significant meaning statistically. CONCLUSION 1. FIM appeared to be a valid and reliable method to measure the functional abilities of the patients after stroke. 2. Only one thing between Motor FIM and score didn't influence FIM score. 3. Dysarthria affected functional recovery in stroke patients, and it is the statistically significant factor.