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Stillbirth rates and their association with swine leucocyte antigen class II haplotypes in Microminipigs

  • Imaeda, Noriaki;Ando, Asako;Matsubara, Tatsuya;Takasu, Masaki;Nishii, Naohito;Miyamoto, Asuka;Ohshima, Shino;Kametani, Yoshie;Suzuki, Shingo;Shiina, Takashi;Ono, Tetsushi;Kulski, Jerzy K.;Kitagawa, Hitoshi
    • Animal Bioscience
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    • v.34 no.11
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    • pp.1749-1756
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    • 2021
  • Objective: Microminipig (MMP) is a miniature pig with an extra small body size for experimental use. In the present study, the occurrence of stillbirths and their genetic association with swine leukocyte antigen (SLA) class II haplotypes were evaluated in a population of MMPs. Methods: The occurrences of stillbirth and genetic association with SLA class II haplotypes using 483 stillborn and 2,246 live piglets, and their parents were compared among the three groups of newborn piglet litters; an all stillborn (AS) group consisting of only stillborn piglet litters, a partial stillborn (PS) group consisting of stillborn and live piglet litters, and an all alive (AA) group consisting of only live piglet litters. Results: The incidence of stillborn piglets was 483/2,729 (17.7%). Distributions of litter sizes, numbers of stillborn piglets in a litter, parities, and gestation periods were distinct among the three groups. The frequencies of low resolution haplotype (Lr)-0.7 or Lr-0.23 were higher in the AS group than in the PS or AA groups. In sires, the frequency of Lr-0.7 associated with the AS group was significantly higher in the AS group than with the AA group. In dams, the frequency of Lr-0.23 was significantly higher in the AS group than in the PS or AA groups, whereas the frequency of Lr-0.7 was not significantly different. Conclusion: The incidence of stillborn piglets in MMPs appears to be higher than those in other pig breeds. Several traits related with stillbirths such as the number of stillborn piglets and parities of the AS group were different from those of the PS and AA groups. Specific SLA class II haplotypes were associated significantly with a high incidence of stillbirths and could be used as genetic markers to adopt breeding strategies to lower the rate of stillbirth in MMPs.

A Study of Analysis Current state of the Apprenticeship Curriculum in Vocational Education and Training High Schools Participating in the Apprenticeship System (산학일체형 도제학교의 도제 교육과정 편성 현황 분석 연구)

  • Ahn, Jae-Yeong
    • Journal of vocational education research
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    • v.36 no.4
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    • pp.57-78
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    • 2017
  • This study aimed to make proposals to develop an apprenticeship program and organize the apprenticeship curriculum by conducting an overall analysis of how vocational education and training high schools participating in the apprenticeship system(apprenticeship schools) organized the apprenticeship program in the school curriculum. To that end, the study analyzed the current state of the apprenticeship curriculum of 33 apprenticeship schools and came up with the following results: First, the apprenticeship class and the general class had a similar relevance between 'departments' and 'areas and goals of student training' and between 'departments' and 'qualifications,' while the apprenticeship class had a higher relevance between 'areas and goals of student training' and 'qualifications' than the general class. Second, both the required and optional competency units of the apprenticeship program were relatively evenly included in the Off-JT and OJT. Third, the competency units of the apprentice program were included in the technical subjects of the 2009 revised curriculum as well as the NCS practical subjects of the 2015 revised curriculum. Fourth, although most of the competency units of the apprenticeship program have a high correlation with the technical subjects of the school curriculum, there were also many schools showing a low correlation. Fifth, although the hierarchy of organizing the competency units of the apprenticeship program by semester was mostly high, there were a considerable number of schools with a low hierarchy. As a result, this study made the following policy proposals: granting a grace period for approval of the changes in the curriculum of the apprenticeship, distributing the matching table before and after the revision of the NCS competency units, organizing subjects not included in the national curriculum, creating subjects specialized for companies, and monitoring and consulting the curriculum of the apprenticeship schools.

Professional Practical of Physical Activities and Support Requests from Child Care Center Teachers of Infants Aged 1 to 2 (어린이집 영아반교사(1~2세반)의 신체활동 실행과 지원요구)

  • Lee, Young Shim
    • Korean Journal of Child Education & Care
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    • v.19 no.2
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    • pp.101-116
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    • 2019
  • Objective: The purpose of this study is to provide basic data on physical activity management plans for different developmental levels in infants. This study analyses the difference between support requests and the professional practical of evaluations, content selection, and physical activity management plans displayed by teachers of one and two-year-old infants. Methods: The subjects of the study were 221 teachers from child care centers throughout J-do to whom a questionnaire containing 51 questions was distributed. Collected data was verified with a chi-squared test and an independent samples t-test. Results: First, among variables of professional practical of physical activities, some factors including class size, class planners and leaders, the number of outdoor classes per week and requisite time, parts of related education plans, parts of content selection for physical activities, and parts of the evaluation of physical activities showed significant differences depending on the class. Second, among variables of support requests when implementing physical activities, some factors including methods of preparing physical activity plans, teaching -learning methods, evaluation methods, body expression activity programs, and parts of physical exercise in the standardized child care curriculum of refresher and extension courses showed significant differences depending on the class. Conclusion/Implications: This study discusses the effective management of refresher and extension courses as a way to improve physical activity management plans and teachers' support requests for infants aged 1 to 2.

A Study on the educational environment according to the teaching and learning method for the realization of the future school - Focused on the consumer needs analysis of K middle school & S middle school - (미래 교수학습방법에 따른 교과교실 교육 환경을 위한 기초 연구 - K중학교 & S중학교 수요자 요구 분석을 중심으로 -)

  • Lee, Jae-Lim
    • The Journal of Sustainable Design and Educational Environment Research
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    • v.21 no.2
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    • pp.11-24
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    • 2022
  • The purpose of this study is to derive a curriculum environment for operating various student-centered teaching and learning methods, and the following results were derived: First, most of the lectures, discussions and consultations, data search, report preparation, presentation, work exhibition, and others were commonly derived, regardless of the types of long-term and short-term project classes for each subject. In particular, the necessity of operating various classes at the same time was suggested, indicating the need for an integrated teaching and learning operation environment in the unit subject class. Second, considering that practical classes are linked concurrently to lectures and discussion classes to conduct one subject class, it is necessary to switch to a specialized curriculum system that allows various classes such as lectures to be carried out at the same time. Third, as a result of grasping the appropriateness of the space size of the subject class for realizing different class types in the future, it can be seen that the space size of the practice room, including the space for practice and the area for exhibition, should be expanded. Based on the research results, the spatial environment for the operation of future teaching and learning classes is based on the public curriculum classroom system, and whether professional curriculum classes, such as lecture rooms and discussion and presentation rooms, are secured according to the number of students.

Towards Achieving the Maximum Capacity in Large Mobile Wireless Networks under Delay Constraints

  • Lin, Xiaojun;Shroff, Ness B.
    • Journal of Communications and Networks
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    • v.6 no.4
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    • pp.352-361
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    • 2004
  • In this paper, we study how to achieve the maximum capacity under delay constraints for large mobile wireless networks. We develop a systematic methodology for studying this problem in the asymptotic region when the number of nodes n in the network is large. We first identify a number of key parameters for a large class of scheduling schemes, and investigate the inherent tradeoffs among the capacity, the delay, and these scheduling parameters. Based on these inherent tradeoffs, we are able to compute the upper bound on the maximum per-node capacity of a large mobile wireless network under given delay constraints. Further, in the process of proving the upper bound, we are able to identify the optimal values of the key scheduling parameters. Knowing these optimal values, we can then develop scheduling schemes that achieve the upper bound up to some logarithmic factor, which suggests that our upper bound is fairly tight. We have applied this methodology to both the i.i.d. mobility model and the random way-point mobility model. In both cases, our methodology allows us to develop new scheduling schemes that can achieve larger capacity than previous proposals under the same delay constraints. In particular, for the i.i.d. mobility model, our scheme can achieve (n-1/3/log3/2 n) per-node capacity with constant delay. This demonstrates that, under the i.i.d. mobility model, mobility increases the capacity even with constant delays. Our methodology can also be extended to incorporate additional scheduling constraints.

An Analysis on argumentation structure development of preservice teachers through argumentative writing on earth science related SSI (지구과학 관련 사회적 문제(socio-scientific issue)와 관련된 논증적 글쓰기를 통해 알아본 예비교사들의 논증구조 발달 분석)

  • Wee, Soo-Meen;Yoon, Ji-Young;Lim, Sung-Man
    • Journal of the Korean Society of Earth Science Education
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    • v.7 no.1
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    • pp.11-23
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    • 2014
  • The purpose of this study is to analyze the degree of argumentation structure development and factors of development of preservice teachers through SSI related argumentative writings. The study was conducted with 16 preservice teachers that students taking elementary science education theory class in K university located in Chungbuk. The testees wrote six SSI related argumentative writings (once a week), and we examined the degree of argumentation structure development and the change in the recognition of SSI of the preservice teachers by comparing the writings before and after the experiments. The experimental results showed that argumentation structure of the preservice teachers'writings improved and argument level (argument capability) of them also increased as the number of writing was increased. Factors that affect the argumentation structure improvement are mainly argumentation structure education, a number of writings, feedbacks, and subjects related to SSI. In this aspect, the argumentative writing on SSI has the effect of developing scientific sophistication and enhancing the decision-making power of students, and it has positive impacts in science education.

DRINKING AS AN EPIDEMIC: A MATHEMATICAL MODEL WITH DYNAMIC BEHAVIOUR

  • Sharma, Swarnali;Samanta, G.P.
    • Journal of applied mathematics & informatics
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    • v.31 no.1_2
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    • pp.1-25
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    • 2013
  • In this paper we have developed a mathematical model of alcohol abuse. It consists of four compartments corresponding to four population classes, namely, moderate and occasional drinkers, heavy drinkers, drinkers in treatment and temporarily recovered class. Basic reproduction number $R_0$ has been determined. Sensitivity analysis of $R_0$ identifies ${\beta}_1$, the transmission coefficient from moderate and occasional drinker to heavy drinker, as the most useful parameter to target for the reduction of $R_0$. The model is locally asymptotically stable at disease free or problem free equilibrium (DFE) $E_0$ when $R_0$ < 1. It is found that, when $R_0$ = 1, a backward bifurcation can occur and when $R_0$ > 1, the endemic equilibrium $E^*$ becomes stable. Further analysis gives the global asymptotic stability of DFE. Our aim of this analysis is to identify the parameters of interest for further study with a view for informing and assisting policy-makers in targeting prevention and treatment resources for maximum effectiveness.

Sialoglycoproteins of Mammalian Erythrocyte Membranes: A Comparative Study

  • Sharma, Savita;Gokhale, Sadashiv M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.12
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    • pp.1666-1673
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    • 2011
  • The presence of sialoglycoproteins (SGPs) in the membranes from goat (Capra aegagrus hircus), buffalo (Bubalus bubalis bubalis) and pig (Sus scrofa domestica) erythrocytes was investigated by partial purification with a chloroform-methanol extraction method followed by Sodium dodecyl sulphate - Polyacrylamide gel electrophoresis in comparison to human (Homo sapiens) erythrocytes. The results show that mammalian erythrocytes possess clear differences in the SGPs numbers and molecular weights although all animals studied in this experiment are from the same class i.e. mammalia. The SGPs number in human, goat, buffalo and pig are four (PAS-1 to PAS-4), ten (PAS-GI to PAS-GX), seven (PAS-BI to PAS-BVII) and four (PAS-PI to PAS-IV) respectively as indicated by staining the polyacrylamide gel with sialoglycoprotein-specific Periodic acid-Schiff's (PAS) stain. The new SGPs could be observed only after the partial purification of membrane fractions named as PAS-HI with molecular weight (Mr) 190 kDa and PAS-HII 150 kDa in human, PAS-BIA in buffalo and PAS-PIA and PAS-PIVA in pig. The gels were also stained with Coomassie brilliant blue (CBB) and Silver stain to check the contamination of other membrane proteins in the purified fractions. The quantitative distribution of SGPs was also determined by densitometry. Present study indicates that there are some basic differences in mammalian erythrocyte membrane SGPs, especially with respect to their number and molecular weights indicating major structural variations.

A novel classification approach based on Naïve Bayes for Twitter sentiment analysis

  • Song, Junseok;Kim, Kyung Tae;Lee, Byungjun;Kim, Sangyoung;Youn, Hee Yong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.6
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    • pp.2996-3011
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    • 2017
  • With rapid growth of web technology and dissemination of smart devices, social networking service(SNS) is widely used. As a result, huge amount of data are generated from SNS such as Twitter, and sentiment analysis of SNS data is very important for various applications and services. In the existing sentiment analysis based on the $Na{\ddot{i}}ve$ Bayes algorithm, a same number of attributes is usually employed to estimate the weight of each class. Moreover, uncountable and meaningless attributes are included. This results in decreased accuracy of sentiment analysis. In this paper two methods are proposed to resolve these issues, which reflect the difference of the number of positive words and negative words in calculating the weights, and eliminate insignificant words in the feature selection step using Multinomial $Na{\ddot{i}}ve$ Bayes(MNB) algorithm. Performance comparison demonstrates that the proposed scheme significantly increases the accuracy compared to the existing Multivariate Bernoulli $Na{\ddot{i}}ve$ Bayes(BNB) algorithm and MNB scheme.

Elementary Education in Korea : A Look to the Future (초등교육)

  • Kim, Chang-Bok;Lee, Kyung-Soon
    • Korean Journal of Child Studies
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    • v.30 no.6
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    • pp.223-235
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    • 2009
  • Elementary education in Korea has variously changed and developed during the last thirty years. Among all the progressive changes, the improvement of teaching conditions is considered to be the most fundamental one. The number of students assigned to a class or a teacher has decreased to a considerable extent. Cyber teaching-learning has been peformed at school and home, and English education has been emerged as a significant part of the Korean public education. The research issues constantly considered essential over the past three decades starting in the 1980's are those related to curricula, teaching-learning methods, training of teachers in-service, and education for upright characters. The practical and political issues should be dealt with to revise the three integrated subjects and text books into a sole integrated subject and text book, to double the credential of teachers in terms of professionalism and to decrease the number of students per teacher in Korea to the OECD level.

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