• 대한수의학회지
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• 제50권4호
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• pp.285-295
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• 2010

Protein expression patterns in Salmonella enterica subspecies enterica serovar Typhimurium (S. Typhimurium) strains with diverse phenotypes, such as phage type, antibiotic resistance pattern and plasmid profiles were examined. For detailed analysis of proteins expressed by different S. Typhimurium strains, protein fractions were divided into detergent-rich phase (DP) and aqueous phase (AP) using triton X-114 detergent. The two phases were subjected to two-dimensional gel electrophoresis (2-DE), followed by protein identification using peptide mass fingerprinting (PMF). In the results, PMF showed that DP fractions consisted mainly of outer membrane proteins, whereas the AP fractions included cytosolic proteins. Comparison of 2-DE profiles of DP did not show any distinct protein spots which could be correlated with phage type, antibiotic resistance pattern or plasmid profile. However, comparisons of 2-DE profiles of the AP revealed differences in the protein spots, which could be correlated with the plasmid profile and phage types. Among these protein spots, flagellin was specific for strains containing a 90 kb plasmid. Compared to DT193 phage type, three protein spots in the range of pI 5.0-5.5 and MW 8-15 kDa of AP 2-DE profiles were absent in the DT104 phage types. Additionally, a protein spot with PI in the range of 4.5-5.0 and molecular weight (MW) between 51-69 kDa was specific for phage type DT104, while a protein spot with pI in the range of 4.0-4.8 and MW between 18-20 kDa was specific for DT193 phage type. These protein spots may be useful for discriminating phage types of S. Typhimurium.

• 대한간호학회지
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• 제27권3호
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• pp.541-549
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• 1997

This study was done to describe health promoting lifestyle and determine affecting factors in elderly based on the Heath Promotion Model by Pender. Cognitive-perceptual factors that were included in this study were self-efficacy and hardiness. Modifying factors were demographic characteristics (sex, age, partner, previous illness, education level. income and religion). The specific purpose of this study was to examine the relationships of self-efficacy, hardiness and the demographic chasteristics to health promoting lifestyle and to determine causal factors affecting the elderly. The subjects were a volunteer sample of 98 elderly in one city in? The instruments for this study were Health Promoting Lifestyle Profile(47items, 4scale), Health Related Hardiness Scale(22i1ems, 6scale), general Self-Efficacy Scale(13i1ems, 5scale). Frequency, percentage, t-test, ANOVA, Pearson's correlation coefficient and Stepwise Multiple regression technique with SAS program were used to analyse the data. The Results of the study are as follows : 1) The average item score for the health promoting lifestyle was 2.63, the highest score on the subscales was interpersonal support (M=3.3), followed by self-actulization(M=2.9), nutrition(M=2.8), stress management(M=2.7), health responsibility(M=2.1) with the lowest bring exercise(M=2.0) 2) A significant difference between education level, income, religion and health promoting lifestyle were found. 3) All of the subscales on health promoting lifestyle were positively related to total hardiness (r=0.330, p<0.001). The hardiness subscale of control was positively related to self-actulization(r=0.276, p<0.01), and commitment was positively related to self-actualization(r=0.315, p<0.001), exercise /nutrition(r=0.245, p<0.01), interpersonal support(r=0.278, p<0.01), stress management(r=0.250, p<0.01). Challenge was positively related to self-actualization(r=0.315, p<0.001), exercise /nutrition(r=0.245, p<0.01). There was no significant correlation between self-efficacy and all of the subscales of health promoting lifestyle. Self-efficacy showed a significant correlation only with control(r=0.469, p<0.001), comittment(r=0.507, p<0.001), challenge (r=0.489, p< 0.001). 4) Comittment, self-efficacy and income explained 25.01% of the variance for the total health promoting lifestyle. The results of this study show that commitment, self efficacy and income predicted the health promoting lifestyle of the elderly. So health promoting programs that increase commitement and self-efficacy should be developed to promote a healthy lifestyle of the elderly, especially those who have low income.

• 대한간호학회지
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• 제35권5호
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• pp.879-887
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• 2005

Purpose: The purpose of this study was to understand depression in women with endometriosis and to identify the factors influencing depression. Method: The instruments used were the Beck Depression Inventory for depression, Lemaire Scale for endometriosis syndrome, Mishel Uncertainty in Illness Scale-Community form (MUIS-C), the Rosenberg Self-esteem Scale, and Quality of Life (Endometriosis Health Profile Questionnaire; EHP-5) by Jones et al. The Subjects of Study were 118 outpatients diagnosed with endometriosis from 7 hospitals in Busan City and Kyungsangnam-do. Data was collected from Aug 1, 2004 to Jan 31, 2005. For statistical analysis of collected data, frequency analysis, analysis of variance, and stepwise multiple regression analysis were used with the SPSS statistical program. Result: The general characteristic showing a statistically significant difference in depression in the women with endometriosis was marital status. The score of the depression showed a significantly positive correlation with the score of endometriosis TSD(r= .464, p= .000), uncertainty(r= .393, p= .000), and quality of life(r= .543, p= .000). Depression showed a significantly negative correlation with the score of self esteem(r= - .557, p= .000). Stepwise multiple regression analysis revealed that the most powerful predictor of depression in the women with endometriosis was self-esteem ($R^2$=0.311). A combination of self esteem, quality of life, and total symptom distress accounted for $50.0\%$ of the variance in depression in women with endometriosis. Conclusion: The influencing factor on depression in women with endometriosis was self- esteem, quality of life, and endometriosis TSD. Further studies need to be done to identify methods of overcoming and the presentation of depression in endometriosis.

• 대한예방한의학회지
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• 제15권3호
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• pp.67-81
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• 2011

Background : Complementary and alternative medicine has bee used to cardiovascular diseases. In recent years, many hospitals have tried to integrate complementary and alternative medicine(CAM) with conventional medical approaches for patients with chronic diseases. Recently, the prevalence of the use of traditional Korean medicine(TKM) among patients with chronic diseases, expecially, hemiplegia patients after cerebrovascular accident is increasing in Korea. To date, however, there were only few studies addressing the patients' attitudes, and utilization of TKM, compared to the well-documented escalating use of TKM among consumers in Korea. Objectives : The objective of this study was to analyze the prevalence of TKM use among hemiplegia patients after cerebrovascular accident and to determine what factors affect to use CAM among the patients. The study also aims to provide information on TKM and assist therapy selection among various CAM therapies for hemiplegia patients after cerebrovascular accident within health care system in which both practitioners of TKM and practitioners of modern Western medicine coexisted. Methods : The design of the study was descriptive cross-sectional, and data were collected using a 32-items questionnaire. The subjects were one hundred fifty nine patients with chronic diseases who visited or admitted to health care facilities in a hospital in Seoul Metropolitan city, Korea. Data were analyzed using 'SPSS Statistics 18.0 Network Version(on release 18.0.1 of PASW Statistics)' program. Various statistical methods were used to obtain a profile for participants and the therapies most frequently used by hemiplegia patients of TKM. Logistic regression analysis was employed in order to determine the predicting variables of TKM use. Results : The prevalence of the use of TKM was 51.6%. The most common TKM therapies used by the patients included acupuncture(93.2%), herbal medicine(64.8%), and cupping(37.5%). Results of logistic regression analysis revealed that the variables significantly related with TKM use were gender, marital status, job, No. of visiting health care facilities/week. Conclusions : This study shows that the use of TKM among the hemiplegia patients is relatively high in Korea, this topic should be taken into account in the development of a holistic approach for patients with chronic diseases and an efficient chronic disease management system in Korea.

• 대한감각통합치료학회지
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• 제8권1호
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• pp.27-40
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• 2010

목적 : 본 연구는 학교 방과 후 활동으로 감각통합치료를 제공하였을 때 작업수행요소와 더불어 작업수행영역인 학교에서의 기능적 과제수행에 미치는 영향을 알아보기 위하여 실시하였다. 연구 방법 : 실험은 대전 Y초등학교에 재학 중인 1-2학년 아동 3명을 대상으로 방과 후 활동 시간에 감각통합치료를 제공하였으며, 중재는 2010년 5월과 6월에 걸쳐 총 25회를 제공하였다. 감각통합치료효과를 알아보기 위해 단일집단 사전-사후 설계(one group pretest-posttest design)를 사용하였고, 작업수행요소에서의 변화를 알아보기 위하여 단축감각프로파일(SSP), 한국판 시지각 발달검사(K-DTVP-2), Bruininks-Oseretsky Test of Motor Proficiency 1(BOTMP)를 사용하였으며, 작업수행영역에서의 변화를 알아보기 위하여 학교에서의 기능적 과제 수행능력에 대한 평가(School Function Assessment)를 사용하였다. 결과 : 방과 후 감각통합프로그램(감각통합치료)을 적용한 결과 대상아동들은 작업수행요소인 단축감각력(SSP), BOTMP, 한국판 시지각 발달검사(K-DTVP-2)의 수치상 향상을 보였으며, 작업수행영역인 학교에서의 기능적 과제 수행(SFA)의 점수에서도 향상을 보였다. 결론 : 본 연구를 통해 방과 후 감각통합프로그램(감각통합치료)이 작업수행요소와 학교에서의 기능적 과제수행에 긍정적인 영향을 미친다는 것을 보여주었지만, 대상의 수가 적어 통계적 유의성을 찾는 데는 한계가 있었다. 따라서 향후 연구에서는 대상자의 수를 고려한 연구들이 필요할 것으로 사료된다.

• 한국치위생학회지
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• 제8권4호
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• pp.153-163
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• 2008

The purpose of this study was to investigate the quality of life of clients who treated and equipped prosthesis in Eulji University Hospital in Dae-Jun City. The results of this study were as follows. The oral status of Female had more carious tooth than male had. Carious tooth(p<0.05) and losed tooth(p<0.001) was more popular in older female. The frequency of treated tooth was higher under 59 years old female than over 60 years old(p<0.01). In education category, carious tooth(p<0.05) and losed tooth(p<0.000) was more popular in low education than high education In the score of relation of OHIP-14 category and general characteristic, female was significantly higher than male in dysfunction( p<0.05), physical disorder(p<0.001) and activity disorder(p<0.05). The score was significantly higher in older than younger in dysfunction(p<0.05), physical disorder(p<0.001) and activity disorder(p<0.001). The score of education was significantly higher in low education group than high education group in physical pain (p<0.001), mental discomfort (p<0.001). The score of marriage status was significantly higher in marriaged group than other group in dysfunction (p<0.05) and mental discomfort (p<0.05). In the score of relation of OHIP-14 category and oral status, the score of carious tooth group was significantly higher in dysfunction(p<0.05), physical disorder(p<0.05) and activity disorder(p<0.05). The score of losed tooth group was significantly higher in dysfunction(p<0.05), physical pain (p<0.05), mental discomfort(p<0.05), physical disorder(p<0.05) and activity disorder(p<0.01). The score of non treated tooth group was significantly higher in dysfunction(p<0.05), mental discomfort(p<0.05), social disorder(p<0.05) and activity disorder(p<0.05). In the score of relation of OHIP-14 category and the sort of prosthesis, the score of being bridge group was significantly higher than being crown group in activity disorder(p<0.05). The OHIP-14 category and the number of prosthesis was not significant relationship. These results suggest that the information and services of the process of dental prosthesis based on subjective evaluation should be provided to clients rather than based on clinical evaluation. The continued system of oral management should be developed and provided.

• 한국사회복지학
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• 제57권3호
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• pp.415-435
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• 2005

본 연구는 '계획된 행동이론'과 '계층적 성격모델'을 이론적 근거로, 65세 이상 고령자의 '은퇴에 대한 재정적 준비행동'을 결정하는 개념적 구조를 고찰하였다. '충주지역 고령인구의 보건 복지실태'의 원자료를 이용하여 65세 이상 노인 253명의 자료를 분석하였다. 구조방정식모형을 이용한 분석결과, '은퇴준비를 위한 재정적 지식'과 '은퇴에 대한 재정적 준비행동' 사이의 인과관계만이 유의미한 것으로 나타났으며 가정된 구조방정식모형의 모형합치도는 매우 높은 것으로 분석되었다. 본 연구의 결과는 성격의 표면적 특성이 행동에 영향을 미친다는 계층적 성격이론과 지식은 행동의도가 실질적 행동으로 표면화되는데 결정적 변인이라는 계획된 행동이론의 논지를 실증하였다. 끝으로, 은퇴에 대한 재정적 준비를 위한 사회적 프로그램의 필요성 등 본 연구가 제안하는 사회복지의 실천적 함의가 논의되었다.

• Preventive Nutrition and Food Science
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• 제13권4호
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• pp.286-291
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• 2008

The objective of this study was to investigate the effects of a nutritional education and physical exercise program on obese children (47 boys and 36 girls). The nutritional education and physical exercise program was provided for 6 weeks and dietary habits, nutrient intake and hematological profiles were measured before and after the program. The BMI (body mass index, $kg/m^2$) in male children was significantly reduced to $24.58{\pm}2.81$ from $25.89{\pm}3.27$ (p<0.01) and it was significantly reduced to $24.29{\pm}3.51$ from $25.21{\pm}3.59$ in female children after the completion of nutritional education and exercise program. Body fat in male children was remarkably reduced to $32.69{\pm}7.74%$ after education from $37.38{\pm}9.21%$ (p<0.001). After the program total cholesterol concentration in male children was reduced to $176.48{\pm}29.10\;mg/dL$ from $196.03{\pm}29.10\;mg/dL$, whereas there was no significant difference in females before and after the nutritional education and exercise program. The grasping power of male children (p<0.05) and backmuscle strength of male (p<0.05) and female children (p<0.001) were significantly increased after the exercise program. The nutrient intakes that were different before and after the nutrition education were calories (p<0.05) and carbohydrate (p<0.05) in male children, and a significant increase in intake of vitamin A (p<0.05) was found in female children. There was a significant difference in meal time regularity before and after program. The findings of this study showed that there was a significant decrease in both body fat and weight, in addition to normalization of hematological profiles after the completion of nutrition education and physical exercise programs.

• 약학회지
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• 제34권1호
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• pp.54-63
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• 1990

These studies were made to assess the present stage of resistance of Shigella species to antibiotics and to find characteristics of R-plasmid of these bacteria. From 1986 to 1988, 125 strains of Shigella species were isolated from patients specimens collected in Chung Cheong-do Hospital, Kyunghee Medical Center, city an provincial health & environmental institutes. These specimens were tested for resistance to 12 kinds of antimicrobial agents by agar dilution method. Using Muller-Hinton agar for the assay of drug resistance and Trypticane Soy Broth as propagating medium for conjugation. All the strains (100%) were resistant to one or more antibiotics. Drug resistance patterns of isolated strains were found as the highest resistance to ampicillin (98%) in 1986, to tetracycline (98%) in 1987, to tetracycline (100%) in 1988, all strains were sensitive to gentamicin, amikacin, tobramycin. Chronologically, resistance decreased gradually as it was shown in relation to kanamycin, rifampicin in 1986, 1987 and 1988, (4%, 2%) (4%, 2%) (0%, 0%) respectively. But, resistance was increased year by year as it was shown in relation to tetracycline, nalidixic acid, streptomycin in 1986, 1987, 1988 (89%, 19%, 45%) (98%, 46%, 71%) and (100%, 58%, 88%). The resistance in correlation to more than 5 drugs, which was 13 strains among 47 strains in 1986, 38 strains among 87 strains in 1987, 23 strains among 26 strains in 1988, was increased gradually. In the transfer test of drug resistance by conjugation methods, the rate which was 3 strains (50%) in 1986, 8 strains (62%) in 1987, 3 strains (100%) in 1988, was increased gradually. When the donor strains were conjugated with the recipient strains, the conjugation rate was high in the multiple resistant strains. The relationships of transferring patterns of drug resistance and molecular weight of R-plasmid were variable. However, only a plasmid which has more than 35 Mgd was transferred.

• 한국컴퓨터정보학회논문지
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• 제20권2호
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• pp.157-167
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• 2015

알코올과 알코올 중독증을 문화적 면에서 연구하는 문헌이 있다. 하지만 사회 내부제도가 변화되면서 음주문화를 변화시킨 정부의 문화개입이 발생하였음에도 불구하고 음주행위나 알코올 중독증의 영향에 관한 연구는 거의 없다고 볼 수 있다. 이 문제는 본 연구의 주목적이다. 연구목적을 달성하기 위하여 연구사례로 몽골을 선정하였으며 몽골의 전통 음주문화 혹은 음주예절의 측정을 위해 몽골의 역사적 근원을 연구해서 1인당음주량, 알코올중독 관련 70년간의 인지도조사, 통계 등 다양한 연구자료에 의해 분석을 하였다. 각종 연구자료 분석 시 몽골의 청년 음주문화가 그들의 조상들이 엄숙하게 따르던 전통음주문화와 맥락부터 많이 변화된 것을 관찰할 수 있었다. 연구결과에 의하면 현대화 관련 음주문화 변화와 음주(소비)간에는 상관성이 있는 것으로 나타났다.