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Evaluation of Peri-procedural Anticoagulation Drug Therapy undergoing Radiofrequency Ablation in Patients with Atrial Fibrillation (심방세동 환자의 고주파 도자절제술 전.후의 항응고약물요법 사용실태 분석)

  • Kim, Su-Hyun;An, Sung-Shim;Kim, Soon-Joo;Bang, Joon-Seok;La, Hyen-Oh
    • Korean Journal of Clinical Pharmacy
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    • v.20 no.2
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    • pp.159-164
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    • 2010
  • Radiofrequency ablation (RA) is being used to manage atrial fibrillation (AF) with patients failed at the $1^{st}$-line anti-arrhythmic medications. Patients undergoing this procedure are at increased risk of thromboembolism after ablation, and anticoagulation management surrounding the ablation remains controversial. Although no conclusive recommendations can be made, published guidelines and data support therapeutic anticoagulation with warfarin. The purpose of this study was to analyze effectiveness of current therapy and to find factors fluctuate International Normalized Ratio (INR) values in patients undergone RA followed by anticoagulation service (ACS). Retrospective review was conducted utilizing database in a hospital. Among 110 patients under warfarin around ablation between January 2006 to September 2007, 54 patients were selected and allocated into 2 groups: Group A included 47 who discontinued warfarin after ablation, while 7 in B continued the medication. Information on demographics, amount and length of warfarin dosing, INR values and measuring frequencies, and the causing factors on INR fluctuation were abstracted. Differences were analyzed using chi-squared test, Fisher's Exact test, and unpaired Student t-test. Mean amount of warfarin before and after surgery was 4.0 mg, 4.1 mg in Group A and was 5.1 mg, 4.6 mg in Group B, respectively. Average duration of warfarin doing before ablation was 73.7 days in Group A, 129.9 days in B with no significant difference (p = 0.312). The duration time of warfarin on groups after ablation lasted several months. The number of checking INRs was 4.1 and 7.6, respectively. Inter-individual variability of INR fluctuations were $2.1{\pm}0.6$ in Group A and $2.2{\pm}0.7$ in B which were not significantly different (p = 0.062). 164 cases of decreased INR were: 'omission in taking medication, stressfulness and headache, 'increased intake of high vitamin K foods', 'lifestyle change of increased physical activities', and 'increase of food-intakes'. To the contrary, 36 cases of increased INR were: 'reduce of food-intake', 'use of non-prescription drugs', 'reduction in physical activities', and 'excessive restriction on food-intake', consecutively. In conclusion, the study validated therapeutic outcomes of RA patients who we treated with standard guideline and demonstrated 9 factors of INR fluctuations in the patient. A well-trained, pharmacist-monitored anticoagulation service could reduce the risk of adverse effects and prevent complications in patients with AF around RA operation.

A Study on the Management System of Bioterrorism by the Phases of Crisis Management (위기관리단계별 생물테러 관리체계에 관한 연구)

  • Kim, Chang-Ho;Lee, Kwang-Lyeol
    • Korean Security Journal
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    • no.13
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    • pp.113-144
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    • 2007
  • The entire world has lived in terror threatened by new-terrorism since the 9.11 terror. Having appeared since 9.11, new-terrorism is new kind of terror targeting victims at random. Bioterrorism is one good example. Since bioterrorism happens secretly, it's hard to identify. The case becomes even harder to detect if it takes the form of a new epidemic. This study set out to apply the four phases of crisis management regarding outbreak and measures of SARS, the latest new epidemic, and to prepare against bioterrorism taking the form of a new epidemic, It also shows the efforts to study what to prepare and what kind of actions to take in case of bioterrorism by applying the four phases. There results demonstrate that the preventive measures against bioterrorism include arranging terror-related laws and identifying and monitoring expected pathogenic organs. In the preparation phases, they should integrate the related agencies, prepare for the standard operating procedures(SOP), execute integrated training sessions among the related agencies, and secure the necessary resources such as vaccine, cures, and exploration devices. In the response phases, they need to set up a rapid diagnosis system, quarantine and then cure the patients, and pursue cooperation from the media and promotions and further an international cooperation system to take appropriate measures. And the final recovery phases should involve offering emergency support by checking the situations and engaging in activities to prevent another terror attack by providing counseling, exchanging information, and analyzing and evaluating the causes.

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Effect of Location Error on the Estimation of Aboveground Biomass Carbon Stock (지상부 바이오매스 탄소저장량의 추정에 위치 오차가 미치는 영향)

  • Kim, Sang-Pil;Heo, Joon;Jung, Jae-Hoon;Yoo, Su-Hong;Kim, Kyoung-Min
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.29 no.2
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    • pp.133-139
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    • 2011
  • Estimation of biomass carbon stock is an important research for estimation of public benefit of forest. Previous studies about biomass carbon stock estimation have limitations, which come from the used deterministic models. The most serious problem of deterministic models is that deterministic models do not provide any explanation about the relevant effects of errors. In this study, the effects of location errors were analyzed in order to estimation of biomass carbon stock of Danyang area using Monte Carlo simulation method. More specifically, the k-Nearest Neighbor(kNN) algorithm was used for basic estimation. In this procedure, random and systematic errors were added on the location of Sample plot, and effects on estimation error were analyzed by checking the changes of RMSE. As a result of random error simulation, mean RMSE of estimation was increased from 24.8 tonC/ha to 26 tonC/ha when 0.5~1 pixel location errors were added. However, mean RMSE was converged after the location errors were added 0.8 pixel, because of characteristic of study site. In case of the systematic error simulation, any significant trends of RMSE were not detected in the test data.

Building an Analytical Platform of Big Data for Quality Inspection in the Dairy Industry: A Machine Learning Approach (유제품 산업의 품질검사를 위한 빅데이터 플랫폼 개발: 머신러닝 접근법)

  • Hwang, Hyunseok;Lee, Sangil;Kim, Sunghyun;Lee, Sangwon
    • Journal of Intelligence and Information Systems
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    • v.24 no.1
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    • pp.125-140
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    • 2018
  • As one of the processes in the manufacturing industry, quality inspection inspects the intermediate products or final products to separate the good-quality goods that meet the quality management standard and the defective goods that do not. The manual inspection of quality in a mass production system may result in low consistency and efficiency. Therefore, the quality inspection of mass-produced products involves automatic checking and classifying by the machines in many processes. Although there are many preceding studies on improving or optimizing the process using the data generated in the production process, there have been many constraints with regard to actual implementation due to the technical limitations of processing a large volume of data in real time. The recent research studies on big data have improved the data processing technology and enabled collecting, processing, and analyzing process data in real time. This paper aims to propose the process and details of applying big data for quality inspection and examine the applicability of the proposed method to the dairy industry. We review the previous studies and propose a big data analysis procedure that is applicable to the manufacturing sector. To assess the feasibility of the proposed method, we applied two methods to one of the quality inspection processes in the dairy industry: convolutional neural network and random forest. We collected, processed, and analyzed the images of caps and straws in real time, and then determined whether the products were defective or not. The result confirmed that there was a drastic increase in classification accuracy compared to the quality inspection performed in the past.

Studies on Organochlorine Pesticide Residues in Livestock Products 3. Organochlorine Pesticide Residues in Milk and Meat (축산식품(畜産食品)의 잔류농약(殘留農藥)에 관(關)한 연구(硏究) 제(第) 3 보(報) 우유(牛乳) 및 식육중(食肉中) 유기염소제(有機鹽素劑)의 잔류량조사(殘留量調査))

  • Cho, Tae Haeng;Whang, Dae Woo;Lee, Moon Han;Lee, Won Chang
    • Korean Journal of Veterinary Research
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    • v.17 no.2
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    • pp.63-71
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    • 1977
  • During the period of March, 1976 to December, 1976, 48 raw milk samples were taken from dairy cows at 48 different dairy farms in Korea analyzed by gas liquid chromatography to determine the seasonal variation of the amount of organochlorine pesticide residues. At the same time 80 market milk, 10 beef and 10 pork samples were analyed by the same procedure for checking residual levels. The results were summarized as follows; 1. Milk samples from 17 dairy farms (36 per cent of tatal) were shown to be contaminated with various organochlorine pesticides. The residua lrate of ${\gamma}-BHC$ in tested samples were 44per cent (14 sam ples) that of aldrine was 28 per cent (9 samples) and those of pp'-DDT, dieldrin and heptachlor were 9.3 percent (3 samples) respectively. 2. In raw milk pp'-DDT, ${\gamma}-BHC$, aldrin, dieldrin and heptachlor were detected, and aldrin, dieldrin and heptachlor were detected in the market milk. Any kinds of organochlorine pesticides were not detected in beef samples but dieldrin and heptachlor were detected in pork samples. Average residual values of aldrin, dieldrin and heptachlor in the market milk were 0.0077 ppm (0.0000~1.1100 ppm), 0.0001ppm (0.0000~0.0500 ppm) and 0.0008 ppm (0.0000~2.0520 ppm), respectively, and those of dieldrin and heptachlor in pork samples were 0.0010 ppm (0.0000~0.0100 ppm) and 0.0033 ppm (0.0000~0.0330 ppm). respectively. 3. Residues of organochlorine pesticides in raw milk were extremely variable; in fact pp'-DDT was detected in milk samples from A, B, C and D districts and endrin was not detected from all districts. The ${\gamma}-BHC$ and dieldrin were detected at the district of A, C and D, aldrin at the districts of A and C and heptachlor at the districts of both A and D. 4. Seasonal trends of residual values of organochlorine pesticides were, in general, noticeable. The residual level was much higher in Spring than in other seasons and showed the tendeney of decrease from spring through summer and autumn generally; in the case of pp'-DDT average residual values were 0.0121 ppm in spring, 0.0022 ppm in summer and not detected in autumn. But in winter ${\gamma}-BHC$ and aldrin residues were increased a little. Residual values in raw milk (when cow are fed on hay and silage) were appeared higher in winter than the other seasons. 5. Residues of organochlorine pesticides in raw milk were not related in respect to hygienic conditions of dairy farms pp'-DDT and heptachlor were, in general, detected in all farms and aldrin was more detected in milk from well sanitated farms than poor sanitated ones.

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The Contents of Emergency Treatment Practice Conducted by Emergency Medical Technician and Related Factors (일부 응급구조사들의 응급처치 시행내용과 관련 요인)

  • Jeong, Sang-Gil;Kim, Ki-Soon;Cho, Soo-Hyung;Kang, Myung-Geun;Han, Mi-Ah
    • Journal of agricultural medicine and community health
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    • v.34 no.3
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    • pp.346-358
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    • 2009
  • Objectives: A study was conducted by analysing the contents and frequency of emergency treatment practiced by emergency medical technicians(EMTs) in emergency situations and contains related factors. Methods: The study subjects included 80 EMTs who participated in ongoing education classes during the period from June 25th to June 26th, 2008. the survey included 53 EMTs employed within 119 first aid teams in fire stations in both a metropolitan city and a medium-sized city. From the survey results relation between frequency of emergency treatment and subjects characteristics explored statistically including t-test, X2 test, Pearson correlation and finally stepwise multiple regression. Results: The most frequent procedure by EMTs checking vital signs. The statistically significant related factors overall of the 23 items of emergency treatment frequency was the working area and the grading of EMT certification. In contrast, significant related factors with frequency of IV linkage were found to be the subjects gender, institution employed and the importance of recognizing the item. The statistically significant related factors of that of ECG monitoring was the gender of respondents. Conclusions: To keep the appropriate frequency of emergency treatment by EMT, active efforts to promote their individual importance and confidence cognition are necessary, especially towards males and persons who have 2nd class certification. Moreover, EMTs who work in small cities must be supported.

Study on development of the remote control door lock system including speeker verification function in real time (화자 인증 기능이 포함된 실시간 원격 도어락 제어 시스템 개발에 관한 연구)

  • Kwon, Soon-Ryang
    • Journal of the Korean Institute of Intelligent Systems
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    • v.15 no.6
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    • pp.714-719
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    • 2005
  • The paper attempts to design and implement the system which can remotely check visitors' speech or Image by a mobile phone. This system is designed to recognize who a visitor is through the automatic calling service, not through a short message, via the mobile phone, even when the home owner is outside. In general, door locks are controlled through the home Server, but it is more effective to control door locks by using DTMF signal from a real-time point of view. The technology suggested in this paper makes it possible to communicate between the visiter and the home owner by making a phone call to tile home owner's mobile phone automatically when the visiter visits the house even if the home owner is outside, and if necessary, it allows for the home owner to control the door lock remotely. Thanks to the system, the home owner is not restricted by time or space for checking the visitor's identification and controlling the door lock. In addition, the security system is improved by changing from the existing password form to the combination of password and speaker verification lot the verification procedure required for controlling the door lock and setting the environment under consideration of any disadvantages which may occur when the mobile Phone is lost. Also, any existing problems such as reconnection to tile network for controlling tile door lock are solved by controlling the door lock in real time by use of DTMF signal while on the phone.

The Research about Efficient Control of the Territorial Base Point (영해기준점의 효율적 유지관리 방안에 관한 연구)

  • Choi, Yun-Soo;Kim, Jae-Myeong;Yun, Chang-Beom
    • Spatial Information Research
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    • v.18 no.1
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    • pp.39-48
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    • 2010
  • Recently, many countries are promoting the rapid development of marine for securing territorial sea. The importance of territorial sea has being emphasized as territorial disputes among countries has been increasing. The South Korea should be encouraged to expand the territory due to territorial disputes with neighborhood countries. The purpose of this study is to derive a improvement plan for the efficient control of the territorial base point through analyzing the existing territorial base point and checking the territorial base point. Therefore, we proposed a variety of new plans for accurate positioning by sea level observation and MBES, reduced the surveying procedure through analyzing the existing territorial base points and provided a basis for the territorial base points which can be the 2nd grade national control points by improving a grade. We also suggested that the territorial base points and sub-territorial base points' database should be given standardized number for increasing the efficient management of other national control points and territorial base points. Finally, we suggested a improved work regulation about analysis and maintenance for territorial base points, the information activity of territorial base points and the new plan of community relations. This study will be a basis for the foundation of maritime territory which could be superior to other countries and the expansion of maritime territory.

Optimal design of a nonparametric Shewhart-Lepage control chart (비모수적 Shewhart-Lepage 관리도의 최적 설계)

  • Lee, Sungmin;Lee, Jaeheon
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.2
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    • pp.339-348
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    • 2017
  • One of the major issues of statistical process control for variables data is monitoring both the mean and the standard deviation. The traditional approach to monitor these parameters is to simultaneously use two seperate control charts. However there have been some works on developing a single chart using a single plotting statistic for joint monitoring, and it is claimed that they are simpler and may be more appealing than the traditonal one from a practical point of view. When using these control charts for variables data, estimating in-control parameters and checking the normality assumption are the very important step. Nonparametric Shewhart-Lepage chart, proposed by Mukherjee and Chakraborti (2012), is an attractive option, because this chart uses only a single control statistic, and does not require the in-control parameters and the underlying continuous distribution. In this paper, we introduce the Shewhart-Lepage chart, and propose the design procedure to find the optimal diagnosis limits when the location and the scale parameters change simultaneously. We also compare the efficiency of the proposed method with that of Mukherjee and Chakraborti (2012).

Performance Analysis of Electronic Personal Dosimeter(EPD) for External Radiation Dosimetry (전자개인선량계(EPD)의 외부피폭방사선량 평가 성능분석)

  • Lee, Byoung-Il;Kim, Taejin;Lim, Young-Khi
    • Journal of Radiation Protection and Research
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    • v.40 no.4
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    • pp.261-266
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    • 2015
  • As performance of electronic personal dosimeter (EPD) used for auxiliary personal dosimeter in nuclear power plants (NPPs) has been being continuously improved, we investigated application cases in Korea and other countries and also tested it in NPPs to assess the performance of EPD for external radiation dosimetry. Result of performance tests done in domestic NPPs was similar to those obtained by IAEA in cooperation with EURADOS (IAEA-TECDOC-1564). In addition, EPD/TLD dose ratio has shown similar tendency of EPD/Film-badge dose ratio from the research by the Japan Atomic Power Company (JAPC) and EPD provided more conservative value than TLD or Film-badge. Although some EPD's failures have been discussed, EPD has shown continuous improvement according to the report of Institute of Nuclear Power Operation (INPO) and data from domestic NPPs. In conclusion, It is considered that the general performance of EPD is adequate for external radiation dosimetry compared with that of TLD, providing appropriate performance checking procedure and alternative measures for functional failure.