• Title/Summary/Keyword: Assessment Framework

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A DNA Microarray LIMS System for Integral Genomic Analysis of Multi-Platform Microarrays

  • Cho, Mi-Kyung;Kang, Jason Jong-ho;Park, Hyun-Seok
    • Genomics & Informatics
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    • v.5 no.2
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    • pp.83-87
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    • 2007
  • The analysis of DNA microarray data is a rapidly evolving area of bioinformatics, and various types of microarray are emerging as some of the most exciting technologies for use in biological and clinical research. In recent years, microarray technology has been utilized in various applications such as the profiling of mRNAs, assessment of DNA copy number, genotyping, and detection of methylated sequences. However, the analysis of these heterogeneous microarray platform experiments does not need to be performed separately. Rather, these platforms can be co-analyzed in combination, for cross-validation. There are a number of separate laboratory information management systems (LIMS) that individually address some of the needs for each platform. However, to our knowledge there are no unified LIMS systems capable of organizing all of the information regarding multi-platform microarray experiments, while additionally integrating this information with tools to perform the analysis. In order to address these requirements, we developed a web-based LIMS system that provides an integrated framework for storing and analyzing microarray information generated by the various platforms. This system enables an easy integration of modules that transform, analyze and/or visualize multi-platform microarray data.

The Development of Protocols for Equitable Testing and Evaluation in Ocean Energy - A Three-Year Strategy

  • Ingram, David M.;Villate, Jose Luis;Abonnel, Cyrille;Johnstone, Cameron
    • International Journal of Fluid Machinery and Systems
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    • v.1 no.1
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    • pp.33-37
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    • 2008
  • EquiMar (Equitable Testing and Evaluation of Marine Energy Extraction Devices in terms of Performance, Cost and Environmental Impact) is one of the first round of energy projects under the European Commissions 7th Framework Programme (FP7). The three year EquiMar project aims to deliver a suite of protocols for the evaluation of both wave and tidal converters, harmonizing testing and evaluation procedures across the wide range of available devices, accelerating adoption through technology matching and improving the understanding of both environmental and economic impacts associated with the deployment of devices. The EquiMar protocols will cover site selection, initial design, scaling up of designs, the deployment of arrays and environmental impact assessment as well as economic issues. EquiMar will build on existing protocols, e.g. UK DTI Marine Renewables Development Fund (MRDF) protocols for wave and tidal energy, and engage with international standards setting activities, e.g. IEC TC114.

Improvements to the analysis of floorbeams with additional web cutouts for orthotropic plated decks with closed continuous ribs

  • De Corte, Wouter;Van Bogaert, Philippe
    • Steel and Composite Structures
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    • v.7 no.1
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    • pp.1-18
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    • 2007
  • Additional cutouts in the floorbeam webs of orthotropic plated bridge decks relieve the highly stressed lower flange of the ribs passing through these floorbeam webs from possible fatigue damage. Conversely, the floorbeam webs themselves suffer from high stress concentrations, especially along the free edges of the additional cutouts. These stresses result from a combination of direct introduction of vertical traffic loads in the weakened web and from the truss action of the floorbeam. The latter differs from a simple beam action due to the presence of the openings and corresponds more to the behaviour of a Vierendeel truss. Close assessment of the appearing stresses, highly relevant for fatigue resistance, requires the use of elaborate finite element modelling. However, a full finite element analysis merely provides the results of total stresses, leaving the researcher or designer the difficult task of finding the origin of these stress components. This paper presents a calculation method for cutout stresses based on a combination of a framework analysis and a two dimensional finite element analysis of much smaller parts of the floorbeam. This method provides more insight in the origin of the stress components, as well as it simplifies any comparison of different additional cutout geometries, independent of the floorbeam topology.

Rapid S-N type life estimation for low cycle fatigue of high-strength steels at a low ambient temperature

  • Feng, Liuyang;Qian, Xudong
    • Steel and Composite Structures
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    • v.33 no.6
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    • pp.777-792
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    • 2019
  • This paper presents a new efficient approach to estimate the S-N type fatigue life assessment curve for S550 high strength steels under low-cycle actions at -60℃. The proposed approach combines a single set of monotonic tension test and one set of fatigue tests to determine the key material damage parameters in the continuum damage mechanics framework. The experimental program in this study examines both the material response under low-cycle actions. The microstructural mechanisms revealed by the Scanning Electron Microscopy (SEM) at the low temperature, furthermore, characterizes the effect due to different strain ratios and low temperature on the low-cycle fatigue life of S550 steels. Anchored on the experimental results, this study validates the S-N curve determined from the proposed approach. The S-N type curve determined from one set of fatigue tests and one set of monotonic tension tests estimates the fatigue life of all specimens under different strain ratios satisfactorily.

Analysis for the changes of the mathematics cognitive domain and for the international achievement in TIMSS (TIMSS 인지영역 평가틀의 변화와 우리나라 학생들의 국제적 수학 성취도)

  • Kim, Sun-Hee
    • Journal for History of Mathematics
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    • v.21 no.3
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    • pp.157-182
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    • 2008
  • TIMSS 2003 is the third and most recently round of IEA's Trends in International Mathematics and Science Study. In this study, I considered the changes of the mathematics cognitive domain in TIMSS and got some facts for developing assessment framework. And I analyzed 7 countries' achievement in the view of our country Korea, i.e. Singapore, Hongkong, Chinese Taipei, Japan, Netherlands, and Unites States. With the reliable and valid achievement scales for cognitive domains given by ISC, students' achievement scales were analyzed according to country, percentile, and sex in each cognitive domain.

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Children and Adolescents' Assessments of Child Friendly Cities (아동 친화적인 도시에 대한 아동.청소년의 인식)

  • Hong, Seung-Ae;Lee, Jae-Yeon
    • Korean Journal of Child Studies
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    • v.32 no.2
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    • pp.53-70
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    • 2011
  • Child Friendly Cities (CFC) is a framework for action with the aim of implementing the UN CRC led by local government in an urban context. A number of surveys with 755 children and adolescents were conducted in order to assess the community's child-friendliness level of Seoul. The results of this study were as follows : 1) Comprehensive assessment of the city's child-friendliness was overall seen to be negative. 2) In regards to the city's child-friendliness, the assessments of Children were more positive than those of the adolescents. 3) Boys assessed the city's child-friendliness more positively than girls. 4) The children and adolescents living in more wealthy communities assessed the city's child-friendliness more positively than those living in poorer areas. This study suggested that a local action plan for the Child Friendly Cities must be implemented to fulfill the CFC standards.

Uncertainty Analysis for Parameters of Probability Distribution in Rainfall Frequency Analysis by Bayesian MCMC and Metropolis Hastings Algorithm (Bayesian MCMC 및 Metropolis Hastings 알고리즘을 이용한 강우빈도분석에서 확률분포의 매개변수에 대한 불확실성 해석)

  • Seo, Young-Min;Park, Ki-Bum
    • Journal of Environmental Science International
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    • v.20 no.3
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    • pp.329-340
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    • 2011
  • The probability concepts mainly used for rainfall or flood frequency analysis in water resources planning are the frequentist viewpoint that defines the probability as the limit of relative frequency, and the unknown parameters in probability model are considered as fixed constant numbers. Thus the probability is objective and the parameters have fixed values so that it is very difficult to specify probabilistically the uncertianty of these parameters. This study constructs the uncertainty evaluation model using Bayesian MCMC and Metropolis -Hastings algorithm for the uncertainty quantification of parameters of probability distribution in rainfall frequency analysis, and then from the application of Bayesian MCMC and Metropolis- Hastings algorithm, the statistical properties and uncertainty intervals of parameters of probability distribution can be quantified in the estimation of probability rainfall so that the basis for the framework configuration can be provided that can specify the uncertainty and risk in flood risk assessment and decision-making process.

IT Service Level Management Using Statistical Method: A Case of H Company (통계적 기법을 이용한 정보기술 서비스 수준관리: H 기업 사례)

  • Yang, Dong-Gu;Kim, Ki-Yoon
    • Information Systems Review
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    • v.8 no.2
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    • pp.211-234
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    • 2006
  • The purpose of IT Service Level Management(SLM) has recently shifted from being a simple financial contract(SLA contract itself) towards a system(SLA management system) for the management of the customer's expectations and the provider's service. The aim of this paper is to introduce and present the systematic SLM using statistical method. We discuss the service level according to two points of view: statistical method and service level management. First, we go into more detail on the objective service level using statistical method. Second, we give an overview of total service level assessment method. The proposed framework enables to measure total service level as IT outsourcing performance quantitatively from the aspect of business strategy.

Injury Assessment and Analysis under Blast Load Using MADYMO (MADYMO를 이용한 폭발 하중에 따른 인체 상해평가 및 분석)

  • Choi, Ho-Min;Kim, Jae-Ki;Pack, In-Seok;Lee, In-Young;Kwon, Dae-Ryeong;Lee, Seok-Soon
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.16 no.1
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    • pp.24-29
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    • 2017
  • There is a need for explosion experiments for explosion-related research. However, there are many restrictions in performing an actual experiment. Therefore, in this paper, an alternative method of overcoming the constraints of an explosion experiment has been conducted using a passenger behavior analysis program called MADYMO to assess and analyze the human body injury due to explosion load. To increase the reliability of the analysis, a drop test has been conducted with the analysis. We provide a new framework for performing the analysis. In future, we will further develop our research with the goal of reducing the opportunity cost for the study of the human body injury.

Quantitative assessment of offshore wind speed variability using fractal analysis

  • Shu, Z.R.;Chan, P.W.;Li, Q.S.;He, Y.C.;Yan, B.W.
    • Wind and Structures
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    • v.31 no.4
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    • pp.363-371
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    • 2020
  • Proper understanding of offshore wind speed variability is of essential importance in practice, which provides useful information to a wide range of coastal and marine activities. In this paper, long-term wind speed data recorded at various offshore stations are analyzed in the framework of fractal dimension analysis. Fractal analysis is a well-established data analysis tool, which is particularly suitable to determine the complexity in time series from a quantitative point of view. The fractal dimension is estimated using the conventional box-counting method. The results suggest that the wind speed data are generally fractals, which are likely to exhibit a persistent nature. The mean fractal dimension varies from 1.31 at an offshore weather station to 1.43 at an urban station, which is mainly associated with surface roughness condition. Monthly variability of fractal dimension at offshore stations is well-defined, which often possess larger values during hotter months and lower values during winter. This is partly attributed to the effect of thermal instability. In addition, with an increase in measurement interval, the mean and minimum fractal dimension decrease, whereas the maximum and coefficient of variation increase in parallel.