• Title/Summary/Keyword: Alternative methods

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Recent Advances in Nanozyme Research for Disease Diagnostics (질병진단을 위한 나노자임 연구의 최근 동향)

  • Shin, Ho Yun;Yoon, Tae Young;Kim, Moon Il
    • KSBB Journal
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    • v.30 no.1
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    • pp.1-10
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    • 2015
  • Nanomaterial-based artificial enzymes (Nanozymes) have attracted recent attention because of their unique advantageous characteristics such as excellent robustness and stability, low-cost production by facile scale-up, and longterm preservation capability that are critically required as an alternative to natural enzymes. These nanozymes exhibit natural enzyme-like activity, and they have been applied to diverse kinds of detection methods for disease-associated biomolecules such as DNAs, proteins, cells, and small molecules including glucose. To highlight the progress in the field of disease diagnostics using nanozyme, this review discusses many nanozyme-based detection methods categorized by the types of target biomolecules. Finally, we address the current challenges and perspectives for the widespread utilization of nanozyme-based disease diagnostics.

Performance Analysis of Quaternion-based Least-squares Methods for GPS Attitude Estimation (GPS 자세각 추정을 위한 쿼터니언 기반 최소자승기법의 성능평가)

  • Won, Jong-Hoon;Kim, Hyung-Cheol;Ko, Sun-Jun;Lee, Ja-Sung
    • Proceedings of the KIEE Conference
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    • 2001.07d
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    • pp.2092-2095
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    • 2001
  • In this paper, the performance of a new alternative form of three-axis attitude estimation algorithm for a rigid body is evaluated via simulation for the situation where the observed vectors are the estimated baselines of a GPS antenna array. This method is derived based on a simple iterative nonlinear least-squares with four elements of quaternion parameter. The representation of quaternion parameters for three-axis attitude of a rigid body is free from singularity problem. The performance of the proposed algorithm is compared with other eight existing methods, such as, Transformation Method (TM), Vector Observation Method (VOM), TRIAD algorithm, two versions of QUaternion ESTimator (QUEST), Singular Value Decomposition (SVD) method, Fast Optimal Attitude Matrix (FOAM), Slower Optimal Matrix Algorithm (SOMA).

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Development of Methods to lmprove the Reliability of ELECTRE (복합기준 평가방법 ELECTRE의 신뢰도 증진을 위한 방안 연구)

  • 이인성
    • Journal of the Korean Institute of Landscape Architecture
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    • v.23 no.1
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    • pp.23-38
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    • 1995
  • ELEECTRE is a less demanding and potentially Bffective multiattribute evaluation method for pre-editing proeedure. The method, however, was developed based on probabilistic mathematicsand its reliability has never'been emprieally tested. This article examined the reliability of ELECTRo under various conditions of linear and non-linear utility func- tions using a Monte-Carlo shnulation, and found the method eausea a considerably high rate of error. To enhance the reliability of ELECTRE, two ways of modi(ication - adjust- ment of threshold values of concordance and discordance matrices, and adjustment of the required nunlber of probably-dominant alternatives to eliminate a probably-dominated alternative - were suggested, and their effctiveness was also tesed by a Monte-Carlo simulation. The simulation result chows that these modifications cponsiderably improve the reliability of ELECTRE, and yet maintain a reasonably high level of efficiency. Through these modifications, ELECTRE can be used as an efficient and feliable pre-editing method. Ways to implement ELECTRE in the construction of plainning decision support systens were discussed. The impli(els combination of this method and other multiattribute evaluation methods will help to create more effective decision suport systems.

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A Study on Water Supply Plans for Horticulture and Livestock Complexes within the Saemangeum Area (새만금 원예·축산단지 용수공급 방안 연구)

  • Choi, Kyung-Sook;Kim, Hae-Do
    • Journal of The Korean Society of Agricultural Engineers
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    • v.54 no.3
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    • pp.125-132
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    • 2012
  • Saemangeum development project is the world's largest tidal flat reclamation project. It is currently under construction, and proceeding with phased developments. The construction of agricultural areas within the Saemangeum reclamed lands is also a part of this project. These areas will have multi-functional complexes aiming to produce mainly eco-friendly horticultural crops and livestock products for the purpose of export. The major concern is to obtain sufficient water with appropriate quality to supply to those areas. The objective of this study is therefore to provide available water supply plans for agricultural purpose, especially for horticulture and livestock complexes. Alternative methods for water supply are purifying water from the Saemangenm lake or using water supply services providing by K-water or local governments. This study investigates to find an economical water supply plan through comparisons of these methods. As a result, the water purification method with Saemangeum lake water could be advantageous for given water supply conditions to horticulture and livestock complexes.

RBAC Method using Certificates (인증서를 이용한 역할기반 접근제어방안)

  • Park, Chong-Hwa;Kim, Ji-Hong
    • The Journal of Information Technology
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    • v.6 no.1
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    • pp.11-20
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    • 2003
  • With the development of Information Communication Technique, electronic commerce using PKIs is widely used over the Internet. The goal of access control is to counter the threat of unauthorized operations involving Web-server or data base systems. The RBAC(Role-Based Access Control) has recently received considerable attention as a promising alternative to traditional discretionary and mandatory access controls. In this paper we propose two methods, the RBAC system using attribute certificates and the RBAC system using SPKI certificates. And we analyze and compare the two methods.

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A compare study on the Evaluation Method of Aircraft Noise (항공기 소음의 평가 척도에 대한 비교 연구)

  • 전지현;안병옥;송민정;장길수;김선우
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2001.11b
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    • pp.703-706
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    • 2001
  • Currently domestic criteria for the aircraft noise is being adapted WECPNL(weighted equivalent continuous perceived noise level), while internationally preferred method is which is originated from $L_{eq}$ and can evaluate even environmental noise. WECPNL used in domestic as a evaluation method is only for the aircraft noise. It is, therefore, not adequate for the evaluation of residents' injury, moreover, it is very difficult to measure the aircraft noise with WECPNL due to the complicated calculating procedures as long as automatic measuring system is not used. Accordingly, this study aims to propose alternative evaluation method for the aircraft noise. To achieve this purpose, the data measured by automatic measuring system were gathered and calculated with three evaluation methods: WECPNL, $L_{eq}$ and $L_{dn}$ and the results calculated from different methods were compared and analyzed.

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Adaptive inverse feedback control of periodic noise for systems with nonminimum phase cancellation path (비최소위상 상쇄계를 가진 시스템을 위한 주기소음의 적응 역 궤환 제어)

  • Kim, Sun-Min;Park, Young-Jin
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2000.11a
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    • pp.437-442
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    • 2000
  • An alternative inverse feedback structure for adaptive active control of periodic noise is introduced for systems with nonminimum phase cancellation path. To obtain the inverse model of the nonminimum phase cancellation path, the cancellation path model can be factorized into a minimum phase term and a maximum phase term. The maximum phase term containing unstable zeros makes the inverse model unstable. To avoid the instability, we alter the inverse model of the maximum phase system into an anti-causal FIR one. An LMS predictor estimates the future samples of the noise, which are necessary for causality of both anti-causal FIR approximation for the stable inverse of the maximum phase system and time-delay existing in the cancellation path. The proposed method has a faster convergence behavior and a better transient response than the conventional FX-LMS algorithms with the same internal model control structure since a filtered reference signal is not required. We compare the proposed methods with the conventional methods through simulation studies.

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An analysis of the effective multimedia transfer modes on internet. (인터넷에서 효율적인 멀티미디어 전송방식 분석)

  • 한계섭
    • Korea Multimedia Society
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    • v.1 no.1
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    • pp.19-32
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    • 1997
  • There are many kinds of predominant modes to transfer Multimedia information on internet in the world. Various methods are applied to get real time multimedia data as possible as we need. At the moment it is very difficult to use acceptable technologies for performe those methods effectively on the Networks. This paper gives the alternative directions and trends for research and development of multimedia transmission on the internet. ATM is one of the best mode to transfer mass-multimedia data at the high speed on the Broad-Band ISDN until now. And xDSL (xDigital Subscriber Line) is an excellent typical method on the PSTN (Public Switched Telephone Network) using old type telephone line. But they are not yet applied into the phase of practical use together this time. So this paper analyzes what we need and how to develop the multimedia transmission modes which we can send on the internet without a problem or any difficulty for our various multimedia information all the time under low cost and high speed.

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The efficacy of chemo-mechanical removal of dental caries

  • Lim, Soon-Bin;Choi, Kyoung-Kyu;Park, Sang-Jin
    • Proceedings of the KACD Conference
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    • 2003.11a
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    • pp.611-612
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    • 2003
  • Mechanical removal in decayed teeth has been performed using drill and sharp hand instruments. These methods have some major disadvantages. Namely mechanical preparation often induces pain, local anesthesia and often leads to overextended cavities. Therefore, to avoid these difficulties, a possible alternative method has been introduced for chemo-mechanical excavation of dentin caries lesions on the market. The purpose of this study was to evaluate the efficacy of between traditional mechanical and chemo-mechanical methods(Carisolv).(omitted)

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Uncertainty quantification and propagation with probability boxes

  • Duran-Vinuesa, L.;Cuervo, D.
    • Nuclear Engineering and Technology
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    • v.53 no.8
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    • pp.2523-2533
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    • 2021
  • In the last decade, the best estimate plus uncertainty methodologies in nuclear technology and nuclear power plant design have become a trending topic in the nuclear field. Since BEPU was allowed for licensing purposes by the most important regulator bodies, different uncertainty assessment methods have become popular, overall non-parametric methods. While non-parametric tolerance regions can be well stated and used in uncertainty quantification for licensing purposes, the propagation of the uncertainty through different codes (multi-scale, multiphysics) in cascade needs a better depiction of uncertainty than the one provided by the tolerance regions or a probability distribution. An alternative method based on the parametric or distributional probability boxes is used to perform uncertainty quantification and propagation regarding statistic uncertainty from one code to another. This method is sample-size independent and allows well-defined tolerance intervals for uncertainty quantification, manageable for uncertainty propagation. This work characterizes the distributional p-boxes behavior on uncertainty quantification and uncertainty propagation through nested random sampling.