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Recent Advances in Nanozyme Research for Disease Diagnostics

질병진단을 위한 나노자임 연구의 최근 동향

  • Shin, Ho Yun (Department of BioNano Technology, Gachon University) ;
  • Yoon, Tae Young (Department of BioNano Technology, Gachon University) ;
  • Kim, Moon Il (Department of BioNano Technology, Gachon University)
  • 신호연 (가천대학교 바이오나노학과) ;
  • 윤태영 (가천대학교 바이오나노학과) ;
  • 김문일 (가천대학교 바이오나노학과)
  • Received : 2014.12.08
  • Accepted : 2015.01.13
  • Published : 2015.02.27
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Abstract

Nanomaterial-based artificial enzymes (Nanozymes) have attracted recent attention because of their unique advantageous characteristics such as excellent robustness and stability, low-cost production by facile scale-up, and longterm preservation capability that are critically required as an alternative to natural enzymes. These nanozymes exhibit natural enzyme-like activity, and they have been applied to diverse kinds of detection methods for disease-associated biomolecules such as DNAs, proteins, cells, and small molecules including glucose. To highlight the progress in the field of disease diagnostics using nanozyme, this review discusses many nanozyme-based detection methods categorized by the types of target biomolecules. Finally, we address the current challenges and perspectives for the widespread utilization of nanozyme-based disease diagnostics.

Keywords

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