• Journal of Ginseng Research
• /
• v.45 no.1
• /
• pp.134-148
• /
• 2021

Background: Lung cancer has a high incidence worldwide, and most lung cancer-associated deaths are attributable to cancer metastasis. Although several medicinal properties of Panax ginseng Meyer have been reported, the effect of ginsenosides Rk1 and Rg5 on epithelial-mesenchymal transition (EMT) stimulated by transforming growth factor beta 1 (TGF-β1) and self-renewal in A549 cells is relatively unknown. Methods: We treated TGF-β1 or alternatively Rk1 and Rg5 in A549 cells. We used western blot analysis, real-time polymerase chain reaction (qPCR), wound healing assay, Matrigel invasion assay, and anoikis assays to determine the effect of Rk1 and Rg5 on TGF-mediated EMT in lung cancer cell. In addition, we performed tumorsphere formation assays and real-time PCR to evaluate the stem-like properties. Results: EMT is induced by TGF-β1 in A549 cells causing the development of cancer stem-like features. Expression of E-cadherin, an epithelial marker, decreased and an increase in vimentin expression was noted. Cell mobility, invasiveness, and anoikis resistance were enhanced with TGF-β1 treatment. In addition, the expression of stem cell markers, CD44, and CD133, was also increased. Treatment with Rk1 and Rg5 suppressed EMT by TGF-β1 and the development of stemness in a dose-dependent manner. Additionally, Rk1 and Rg5 markedly suppressed TGF-β1-induced metalloproteinase-2/9 (MMP2/9) activity, and activation of Smad2/3 and nuclear factor kappa B/extra-cellular signal regulated kinases (NF-kB/ERK) pathways in lung cancer cells. Conclusions: Rk1 and Rg5 regulate the EMT inducing TGF-β1 by suppressing the Smad and NF-κB/ERK pathways (non-Smad pathway).

• The Journal of the Korea Contents Association
• /
• v.20 no.12
• /
• pp.154-165
• /
• 2020

With a long-lasting pandemic of COVID-19, we have faced unprecedented socioeconomic threats. The regulation of human exchange has exposed us not only to the threat of health and medical care problems, but also to the burden of the contraction of economic activity. The outbreak of COVID-19 did give us an opportunity to reexamine the social safety net which has been prepared for such crisis situations. The current study, in this vein, aims to investigate the impact of evaluations of social safety nets on the trust in government and on individual willingness to accept tax increases. To this end, this study has explored the data from a survey conducted on 1,000 adult men and women across the country (South Korea) in May, 2020, when COVID-19 has entered a pandemic phase. The analysis result then has shown that the evaluation of social safety net after the outbreak of COVID-19 had a positive impact on the trust in the government, which in turn led to the increase of the willingness to accept tax increases. Moreover, the positive impact of trust in government on the willingness to accept tax increases has been more amplified when the income level was increased. These results could contribute to laying the theoretical foundation for restructuring the policies and systems for the post COVID-19 era.

• Journal of the Korea Society of Computer and Information
• /
• v.25 no.12
• /
• pp.279-291
• /
• 2020

It has already been a few years since the word Fintech in Korea started to attract attention. These days, they believed that Fintech was just a boom, but these days it is recognized as a catalyst for financial transformation. Large venture companies are also launching demonstration experiments by creating new organizations that can respond to Fintech. It feels like a big tide is coming to the cautious and conservative financial industry. Finance is made up of digital information. Fintech is an evolutionary process in which finance, expressed by digital information, is transformed into information technology (IT) and human economic activities are reorganized. It is FinTech. You won't be able to understand the real effects of Fintech by sticking to individual applications like remittance payments or household account book services. Fintech is an innovation that changes the structure of economic activity itself. In fact, it is from now on that a big impact will come. In other words, now is the time when we are thinking of a dream that we have not yet dreamed of. In this paper, I will examine how fintech originated, spread to Korea, and how it intends to change Korea's finance in the future. Financial institutions have used the fruits of information technology advances in the direction of pursuing stability and stability, without major changes in the way they work. However, the movement of Fintech that started in Silicon Valley in the United States shows that the fruit can be used in other directions. The fruit of technological progress is expected to expand year by year in the future. It is a request of the times to use it to improve user convenience and to pursue innovation that is beneficial to society. We expect the flow of Fintech to accelerate innovation in the Korean financial industry.

• Applied Chemistry for Engineering
• /
• v.31 no.6
• /
• pp.674-678
• /
• 2020

In this study, a Pd/TiO2 catalyst which oxidized H2 at room temperature without an additional energy source was prepared. And a specific surface area of TiO2 as a support was not proportional to H2 oxidation reaction performance of Pd/TiO2 catalyst. In addition La2O3 was added to Pd/TiO2 catalyst in order to evaluate the performance effect due to the change of catalysts physical properties. A Pd/La2O3-TiO2 was prepared by adding different amounts of La2O3 to TiO2 and CO chemisorption analysis was performed. Compared to the conversion rate (14% at 0.5% H2) of the Pd/TiO2(G) catalyst, the Pd/La2O3-TiO2 catalyst showed 74% which was improved by more than five times. It was found that the larger the metal dispersion of Pd as an active metal is, the more favorable to H2 oxidation reaction is. However, when the added La2O3 amount exceeded 10%, the catalyst performance decreased again. Finally, it was concluded that the physical properties of the Pd/La2O3-TiO2 catalyst have a dominant influence on the catalytic activity until 0.3~0.5% of injected H2 concentrations and the catalyst reaction rate was controlled by substance transfer from 1% or more concentrations of H2.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.27 no.1
• /
• pp.135-144
• /
• 2021

In this study, we investigated the characteristics of the process of hydrogen production using boil-of gas (BOG) generated from an LNG-fueled ship and the application of hydrogen fuel cell systems as auxiliary engines. In this study, the BOG steam reformer process was designed using the UniSim R410 program, and the reformer outlet temperature, pressure, and the fraction and consumption of the product according to the steam/carbon ratio (SCR) were calculated. According to the study, the conversion rate of methane was 100 % when the temperature of the reformer was 890 ℃, and maximum hydrogen production was observed. In addition, the lower the pressure, the higher is the reaction activity. However, higher temperatures have led to a decrease in hydrogen production owing to the preponderance of adverse reactions and increased amounts of water and carbon dioxide. As SCR increased, hydrogen production increased, but the required energy consumption also increased proportionally. Although the hydrogen fraction was the highest when the SCR was 1.8, it was confirmed that the optimal operation range was for SCR to operate at 3 to prevent cocking. In addition, the lower the pressure, the higher is the amount of carbon dioxide generated. Furthermore, 42.5 % of the LNG cold energy based on carbon dioxide generation was required for cooling and liquefaction.

• Korean Journal of Remote Sensing
• /
• v.36 no.6_3
• /
• pp.1721-1732
• /
• 2020

Elementary school students spend a lot of time in a school and are more exposed to indoor air pollution. Also the students are physically growing and have a relatively high respiratory rate per unit weight compared to adults, so it is known that there is a high sensitivity to indoor air pollution. Therefore, indoor air quality in a school is becoming an important factor for the student's health. In this study, a correlation analysis using levels of indoor and outdoor Particulate Matter (PM) measured from five elementary schools in Seoul was performed to evaluate the effect of outdoor PM on indoor PM. PM ratio and indoor/outdoor (I/O) ratio were also analyzed to investigate the actual condition of indoor air quality and effect of outdoor PM on indoor PM. As a result, the correlation between indoor and outdoor PM in elementary school was more significant in PM2.5 and PM1 than PM10. In the case of I/O ratio, the I/O ratio of PM10 was higher than that of 1 in four elementary schools except SD (BB:2.21, NS: 1.67, IS: 1.73, SI: 1.17). This indicates that the activity of students has a great effect on the concentration of indoor PM10.

• Journal of Korean society of Dental Hygiene
• /
• v.21 no.4
• /
• pp.467-479
• /
• 2021

Objectives: The purpose of this study was to investigate the awareness of the performance and necessity of oral health promotion activities and seek ways to revitalize the professional role of dental hygienists in oral healthcare for the efficient oral care of the elderly. Methods: Eighty-five dental hygienists in charge of oral health promotion projects at public health centers and 38 dental hygienists in network dental clinical trials were investigated for their learning experience, performance experience, feasibility, and necessity of dental hygienists for general and oral health service items for the elderly. The collected data were analyzed using frequency analysis, chi-square test, and Mann-Whitney U test. Results: The degree of performance possibility according to the learning experience and performance experience of the dental hygienist for the whole body and oral health promotion activity items for the elderly showed that the degree of performance possibility was higher among those with experience compared to the non-experienced person, and it was statistically significantly higher (p<0.05). Conclusions: The dental hygienist's professional oral health service is a necessary system to improve practical knowledge and skills and to provide a wide range of professional oral health services for the elderly.

• The Journal of the Korea Contents Association
• /
• v.21 no.5
• /
• pp.398-408
• /
• 2021

The purpose of this study is to verify the mediating effects of difficult in emotional regulation and perceived social support on the relationship between adult ADHD tendency and smartphone addiction. For this study, Data were collected from 348 adults in 20s to 30s who live in Seoul, Gyeong-Gi Provinces. The SPSS 21.0 program was used to analyze the statistical data. The data was analyzed by structural equation modeling test mediating effects with AMOS and Mplus.. The results of the analysis were as follows: First adult ADHD tendency was positively correlated with difficulties in emotional regulation and smart phone addiction, while perceived social support was negatively correlated with those variables. Second difficulties in emotional regulation was partially mediated adult ADHD tendency and perceive social support. Third difficulties in emotional regulation and perceived social support had a dual mediating effect on adult ADHD tendency and smartphone addiction. These results reiterate the difficulties in emotional regulation is a determinant for the influence of adult ADHD on smartphone addiction, and suggest that smartphone addiction as an avoidant alternative activity could be reduced by overcoming the difficulties in emotional regulation and promoting the perceived social supports. Finally, some limitations of this study and suggestions for further researches were discussed.

• Journal of Korean Library and Information Science Society
• /
• v.52 no.2
• /
• pp.145-166
• /
• 2021

The study was aimed at verifying the effectiveness of Book-Coding reading education as a reader activity of older elementary school children at a time when high-dimensional thinking abilities were formed. To this end, 30 fifth-grade children of N Elementary School in N-si, Gyeonggi-do, comprised of 15 students from a reading education program using Book-Coding, and 15 students from a reading comprehension program, and applied the reading education program over a total of 12 sessions. The main results of the study are summarized as follows. First, when the effects of the convergence reading education program using Book-Coding on the logical thinking ability of the students in the upper grades in the elementary school were analyzed, all the six sub-factors of logical thinking ability, that is, conservation logic, proportional logic, variable controlling logic, probabilistic logic, correlational inference logic, and combinational logic, were proved to have statistically more meaningful difference than the group writing a book report. Second, the analysis result of the influence of the convergence reading education program using Book-Coding on the creativity of the students in the upper grades of the elementary school showed that all the 13 elements of curiosity, persistence, effectiveness, independence, adventurousness, openness, knowledge, imagination, originality, sensitivity, fluency, flexibility, and accuracy were statistically meaningfully different compared to the book report group. Third, when it was analyzed how the convergence reading education program using Book-Coding affected the creative personality of the elementary school students, all the six factors of curiosity, task commitment, independence, awareness of risk, and openness of thinking, and aesthetics were found out to have a statistically more meaningful difference than the group that wrote a book report.

• Journal of the Korean Institute of Traditional Landscape Architecture
• /
• v.39 no.4
• /
• pp.1-9
• /
• 2021

The purpose of this study was to determine the definition of traditional landscape and the appropriate English notation. To confirm the appropriate concept, the charter's relevant terminology was synthesised and the meaning of the vocabulary used in international studies was examined. ICOMOS The Charter on Historic Gardens(The Florebce Charter, 1981), ICOMOS-IFLA Document on Historic Urban Parks(New Delhi, 2017), and UNESCO Recommendation on The Historic Urban Landscape(Paris, 2011) were analysed to examine the concept, and the words describing definitions, space, objects, value, and activity were arranged. Big data was used to analyse the research literature related to overseas traditional landscapes. This study examined the characteristics of each word and examined the appropriate name for expressing the historic and cultural characteristics of landscape in research literature, which included traditional, historic, cultural, classical, vernacular, landscape-related gardens, parks, and landscape words related to historic culture. Consequently, the International Charter declared the suitability of 'historic' gardens and parks, as well as traditional landscape for expressing unique designs, composition technique, and ecological meaning of Korea, while historic landscape was deemed suitable for explaining gardens and parks in landscape history.